For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Retail
1
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
  • Hospitality
  • Sports & Entertainment
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

Florence County, SC Retail Properties for Lease

18 results
List
Map
Versatile Commercial Space in Florence
$5,000 / Mo
11,390 SF

Versatile Commercial Space in Florence

374 Darlington St, Florence, SC 29501

Commercial property with bay doors, ideal for automotive or warehouse.

  • Prime Downtown Florence, SC location
  • Multiple bay doors for easy access and operations
  • Versatile space suitable for automotive, warehouse, or service‑related businesses
  • Abundant open space for vehicles, equipment, or flexible use
  • Dedicated office space for administrative functions
Updated: Oct 11, 2025
View details
Restaurant Space Near I-95
$7,680 / Mo
4,190 SF

Restaurant Space Near I-95

3751 W Palmetto St, Florence, SC 29501

Restaurant space for lease with high visibility and traffic.

  • High traffic location with 36,300 vehicles daily on I‑95 and 17,800 vehicles daily on US‑76.
  • Excellent visibility and accessibility with copious road frontage, two driveway entrances, and ample parking.
  • Located off I‑95 Exit 157.
  • Surrounded by established national brands (McDonald’s, Waffle House, etc.).
  • 4,190 SF restaurant space available for lease.
Updated: Sep 2, 2025
View details
Restaurant Space Near I-95
$7,680 / Mo
4,190 SF

Restaurant Space Near I-95

Restaurant space for lease with high visibility and traffic.

3751 W Palmetto St, Florence, SC 29501
View details
Retail Space in Florence, SC
Contact for pricing

Retail Space in Florence, SC

Located at a busy intersection with high visibility and access.

Florence, SC 29501
View details
Retail Space in Regional Destination
Contact for pricing
4,475 SF

Retail Space in Regional Destination

Retail spaces available in premier shopping destination near major highways.

110 Woody Jones Blvd, Florence, SC 29501
View details
Retail Space in Regional Destination
Contact for pricing
2,400 SF

Retail Space in Regional Destination

Retail spaces available in premier shopping destination, built in 2015.

104 Woody Jones Blvd, Florence, SC 29501
View details
Retail Space in Regional Destination
Contact for pricing
2,800 SF

Retail Space in Regional Destination

Retail space available in premier shopping center, built in 2015.

112-120 Woody Jones Blvd, Florence, SC 29501
View details
Retail Space in Lake City
Contact for pricing
1,200 SF

Retail Space in Lake City

Retail spaces available in a busy Lake City shopping center.

252 Kelley St, Lake City, SC 29560
View details
Retail Space in Florence, SC
Contact for pricing
8,000 SF

Retail Space in Florence, SC

8,000 SF retail space available for lease.

2600 David H Mcleod Blvd, Florence, SC 29501
View details
Claussen Retail Center Space Available
$12 SF/Yr
47,905 SF

Claussen Retail Center Space Available

Grocery-anchored retail space in Florence, SC.

2332 Pamplico Hwy, Florence, SC 29505
View details
Downtown Florence Mixed-Use Gem
$25 SF/Yr
7,748 SF

Downtown Florence Mixed-Use Gem

Historic District, prime location, flexible space.

127 Evans St, Florence, SC 29501
View details
West End District Warehouse
$90 SF/Yr
36,360 SF

West End District Warehouse

36,360 SF Warehouse, Prime Location

2295 Hoffmeyer Rd, Florence, SC 29501
View details
Southside Commons Retail Space
Contact for pricing
37,488 SF

Southside Commons Retail Space

Florence, SC Retail Center - 1 Space Available

2014 Irby St, Florence, SC 29505
View details
Florence Crossing Retail Center
$22 SF/Yr
9,775 SF

Florence Crossing Retail Center

Prime Retail Space Available in Florence, SC

100-110 Woody Jones Blvd, Florence, SC 29501
View details
Florence Mall Retail Space
Contact for pricing
329,345 SF

Florence Mall Retail Space

Prime Florence, SC retail center

1945 Palmetto St, Florence, SC 29501
View details
Logan Plaza: Prime Office Space
Contact for pricing
7,900 SF

Logan Plaza: Prime Office Space

Florence, SC Office Suites Available

1800 2Nd Loop Rd, Florence, SC 29501
View details
Irby Street Retail Opportunity
Contact for pricing
86,324 SF

Irby Street Retail Opportunity

High-traffic retail space available

1611 Irby St, Florence, SC 29505
View details
Langston Loop Outparcel: Prime Retail Site
Contact for pricing
32,670 SF

Langston Loop Outparcel: Prime Retail Site

Florence, SC retail land: build-to-suit or ground lease.

500 2Nd Loop Rd, Florence, SC 29505
View details
Based on your search, we've compiled 39 Potential Opportunities for your consideration. Besides 18 Active listings in Florence County, SC, we suggest exploring alternatives. Similar 21 Properties for Sales.

Explore Similar Spaces for Sale in Florence County, SC

Consider Similar Space for Sale. We found 21 Spaces in Nearby Locations matching your search parameters.

Versatile Commercial Property Near Downtown
$550,000
67,518 SF

Versatile Commercial Property Near Downtown

Office, showroom, and warehouse space near downtown Florence, SC.

121 Lawson St, Florence, SC 29501
View details
Industrial Buildings with Power & Access
$199,000
40,000 SF

Industrial Buildings with Power & Access

Two industrial buildings ideal for fabrication, automotive, or storage.

120 N Guerry St, Florence, SC 29501
View details
Established Auto Body Business For Sale
$1,305,000
4,125 SF

Established Auto Body Business For Sale

Turn-key auto body business with equipment, client roster, and real estate.

803 Ranch Rd, Florence, SC 29506
View details
Olanta Commercial Building on US 301
$75,000
1,500 SF

Olanta Commercial Building on US 301

Commercial building in Olanta, SC, with restaurant and retail potential.

405 N Jones Rd, Olanta, SC 29114
View details
Florence Commercial Building on Evans
$79,000
1,200 SF

Florence Commercial Building on Evans

Standalone building on Evans Street with redevelopment potential.

617 W Evans St, Florence, SC 29501
View details
Commercial Lot in Lake City
$160,000
0.47 Acres

Commercial Lot in Lake City

0.47 acre commercial lot with rental income potential.

0.47 Acres-Tbd Sumter St, Lake City, SC 29560
View details

Florence County, SC Retail properties Leasing Opportunities Market Analysis

Explore Retail properties leasing options in Florence County, SC with 39 listings featured on our commercial real estate exchange. The current inventory includes 5,295,066,480 square feet of properties with an estimated lease value of $198 SF/Yr.

Estimated lease rates for Retail properties in Florence County, SC begin at $5 SF/Yr, with an average of $28 SF/Yr and extend to $90 SF/Yr.
List
Map