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    Florence County, SC Retail Properties for Lease

    17 results
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    Restaurant Space Near I-95
    $7,680 / Mo
    4,190 SF

    Restaurant Space Near I-95

    3751 W Palmetto St, Florence, SC 29501

    Restaurant space for lease with high visibility and traffic.

    • High traffic location: 36,300 vehicles daily on I‑95 and 17,800 on US‑76.
    • Excellent visibility and accessibility: Copious road frontage and two driveway entrances.
    • Ample parking available.
    • Located off I‑95 Exit 157.
    • Surrounded by established national brands.
    Updated: Aug 28, 2025
    View details
    Restaurant Space Near I-95
    $7,680 / Mo
    4,190 SF

    Restaurant Space Near I-95

    3751 W Palmetto St, Florence, SC 29501

    Restaurant space for lease with high visibility and traffic.

    • High traffic location with 36,300 vehicles daily on I‑95 and 17,800 vehicles daily on US‑76.
    • Excellent visibility and accessibility with copious road frontage, two driveway entrances, and ample parking.
    • Located off I‑95 Exit 157.
    • Surrounded by established national brands (McDonald’s, Waffle House, etc.).
    • 4,190 SF restaurant space available for lease.
    Updated: Sep 2, 2025
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    Versatile Commercial Space in Florence
    $5,000 / Mo
    11,390 SF

    Versatile Commercial Space in Florence

    Commercial property with bay doors, ideal for automotive or warehouse.

    374 Darlington St, Florence, SC 29501
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    Claussen Retail Center Space Available
    $12 SF/Yr
    47,905 SF

    Claussen Retail Center Space Available

    Grocery-anchored retail space in Florence, SC.

    2332 Pamplico Hwy, Florence, SC 29505
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    Florence Crossing Retail Center
    $22 SF/Yr
    9,775 SF

    Florence Crossing Retail Center

    Prime Retail Space Available in Florence, SC

    100-110 Woody Jones Blvd, Florence, SC 29501
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    Irby Street Retail Opportunity
    Contact for pricing
    86,324 SF

    Irby Street Retail Opportunity

    High-traffic retail space available

    1611 Irby St, Florence, SC 29505
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    Logan Plaza: Prime Office Space
    Contact for pricing
    7,900 SF

    Logan Plaza: Prime Office Space

    Florence, SC Office Suites Available

    1800 2Nd Loop Rd, Florence, SC 29501
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    Southside Commons Retail Space
    Contact for pricing
    37,488 SF

    Southside Commons Retail Space

    Florence, SC Retail Center - 1 Space Available

    2014 Irby St, Florence, SC 29505
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    Downtown Florence Mixed-Use Gem
    $25 SF/Yr
    7,748 SF

    Downtown Florence Mixed-Use Gem

    Historic District, prime location, flexible space.

    127 Evans St, Florence, SC 29501
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    Florence Mall Retail Space
    Contact for pricing
    329,345 SF

    Florence Mall Retail Space

    Prime Florence, SC retail center

    1945 Palmetto St, Florence, SC 29501
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    West End District Warehouse
    $90 SF/Yr
    36,360 SF

    West End District Warehouse

    36,360 SF Warehouse, Prime Location

    2295 Hoffmeyer Rd, Florence, SC 29501
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    Retail Space in Regional Destination
    $22 SF/Yr
    2,800 SF

    Retail Space in Regional Destination

    Retail space available in premier shopping center, built in 2015.

    112-120 Woody Jones Blvd, Florence, SC 29501
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    Retail Space in Regional Destination
    $25 SF/Yr
    2,400 SF

    Retail Space in Regional Destination

    Retail spaces available in premier shopping destination, built in 2015.

    104 Woody Jones Blvd, Florence, SC 29501
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    Retail Space in Regional Destination
    $22 SF/Yr
    4,475 SF

    Retail Space in Regional Destination

    Retail spaces available in premier shopping destination near major highways.

    110 Woody Jones Blvd, Florence, SC 29501
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    Retail Space in Lake City
    $3 SF/Yr
    1,200 SF

    Retail Space in Lake City

    Retail spaces available in a busy Lake City shopping center.

    252 Kelley St, Lake City, SC 29560
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    Retail Space in Florence, SC
    Contact for pricing
    8,000 SF

    Retail Space in Florence, SC

    8,000 SF retail space available for lease.

    2600 David H Mcleod Blvd, Florence, SC 29501
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    Retail Space in Florence, SC
    Contact for pricing

    Retail Space in Florence, SC

    Located at a busy intersection with high visibility and access.

    Florence, SC 29501
    View details
    Based on your search, we've compiled 37 Potential Opportunities for your consideration. Besides 17 Active listings in Florence County, SC, we suggest exploring alternatives. Similar 20 Properties for Sales.

    Explore Similar Spaces for Sale in Florence County, SC

    Consider Similar Space for Sale. We found 20 Spaces in Nearby Locations matching your search parameters.

    Established Auto Body Business For Sale
    $1,305,000
    4,125 SF

    Established Auto Body Business For Sale

    Turn-key auto body business with real estate in Florence, SC.

    803 Ranch Rd, Florence, SC 29506
    View details
    Olanta Commercial Building on US 301
    $75,000
    1,500 SF

    Olanta Commercial Building on US 301

    Commercial building in Olanta, SC, with restaurant and retail potential.

    405 N Jones Rd, Olanta, SC 29114
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    Commercial Lot in Lake City
    $160,000
    0.47 Acres

    Commercial Lot in Lake City

    0.47 acre commercial lot with rental income potential.

    0.47 Acres-Tbd Sumter St, Lake City, SC 29560
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    Retail Property in Prime Location
    $1,389,000
    4,160 SF

    Retail Property in Prime Location

    Single-tenant net-leased The Vitamin Shoppe in Florence, SC.

    2590 David H Mcleod Blvd, Florence, SC 29501
    View details
    Historic Mixed-Use Building in Florence
    $3,000,000
    13 SF

    Historic Mixed-Use Building in Florence

    16,000 sq ft historic building in Downtown Florence for sale.

    248 W Evans St Florence, Florence, SC 29501
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    Pamplico Highway Commercial Opportunity
    $229,900
    0.80 Acres

    Pamplico Highway Commercial Opportunity

    Commercial lot on heavily traveled Pamplico Highway with multiple driveways.

    1424 Pamplico Hwy, Florence, SC 29505
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    Wendy's Restaurant For Sale
    Contact for pricing
    2,058 SF

    Wendy's Restaurant For Sale

    Wendy’s in Florence, South Carolina, leased for 20 years.

    4010 E Palmetto St, Florence, SC 29501
    View details

    Florence County, SC Retail properties Leasing Opportunities Market Analysis

    Explore Retail properties leasing options in Florence County, SC with 37 listings featured on our commercial real estate exchange. The current inventory includes 5,768,781,480 square feet of properties with an estimated lease value of $270 SF/Yr.

    Estimated lease rates for Retail properties in Florence County, SC begin at $3 SF/Yr, with an average of $24 SF/Yr and extend to $90 SF/Yr.
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    Retail properties by market

    Browse Retail properties for Lease Near Florence, SC

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