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    Madison County, IL Office Space for Lease

    39 results
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    Versatile Industrial Space in Godfrey
    $12 SF/Yr
    133,154 SF

    Versatile Industrial Space in Godfrey

    4436 Industrial Dr, Alton, IL 62002

    Industrial property with office and shop space for lease.

    • 15,100 sq ft versatile space: 9,421 sq ft of office and 5,679 sq ft of shop space.
    • Highway visibility and convenient access to MCT bus stops and the interstate.
    • Includes two outbuildings (24' x 24' and 74' x 36') for extra storage or specialized work areas.
    • Shop space features 6 oversized garage doors and an oil separator system.
    • Office area includes 3 ADA compliant bathrooms (with showers), 2 kitchens, and a lunch room with seating for 30.
    Updated: Nov 20, 2025
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    Alton Retail/Office Space Available
    $9 SF/Yr
    21,625 SF

    Alton Retail/Office Space Available

    90 North Prt Dr, Alton, IL 62002

    Highly visible retail or office space with flexible uses.

    • High visibility location on Hwy 67 and Homer Adams Parkway with 23,150 combined VPD
    • Versatile C‑2 General Commercial zoning allows for a wide range of uses
    • Handicap accessible with four ADA restrooms and accessible entry door
    • Loading dock with 10 x 10 overhead door and 14 x 18 loading area
    • Open floor plan with 10‑foot ceilings
    Updated: Jan 1
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    Alton Retail/Office Space Available
    $13 SF/Yr
    21,265 SF

    Alton Retail/Office Space Available

    Visible retail/office space with high traffic and flexible use.

    94 North Prt Dr, Alton, IL 62002
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    Versatile Commercial Space Available
    $5,000 / Mo
    5,000 SF

    Versatile Commercial Space Available

    Adaptable office space with modern finishes and customization options.

    1902 Vandalia St, Collinsville, IL 62234
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    Office Suite in Edwardsville, IL
    $500 / Mo

    Office Suite in Edwardsville, IL

    Single office suite for lease with utilities included.

    340 S Fillmore St, Edwardsville, IL 62025
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    Class A Office Space
    $2,300 / Mo

    Class A Office Space

    Prime office space in Edwardsville, IL for lease.

    3 Club Centre Ct, Edwardsville, IL 62025
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    Commercial Space in Alton, IL
    $950 / Mo
    10,955 SF

    Commercial Space in Alton, IL

    One-story brick building suitable for commercial use in Alton.

    2201 State St, Alton, IL 62002
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    Alton Office Space for Lease
    $700 / Mo
    30,980 SF

    Alton Office Space for Lease

    Office space available in full-service building with parking.

    307 Henry St, Alton, IL 62002
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    Alton Office/Retail Space For Rent
    $13 SF/Yr

    Alton Office/Retail Space For Rent

    Highly visible office/retail space near Alton Square Mall.

    235 E Center Dr, Alton, IL 62002
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    Collinsville Office Space For Lease
    $600 / Mo

    Collinsville Office Space For Lease

    Approximately 1500 sq ft office space available for lease.

    101 St Louis Rd, Collinsville, IL 62234
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    Office Space in Honke Building
    $665 / Mo
    500 SF

    Office Space in Honke Building

    500 SF office space available for lease in Alton.

    307 Henry St, Alton, IL 62002
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    Class A Office Space Available
    $1,500 / Mo
    3,603 SF

    Class A Office Space Available

    Class A office space with receptionist, utilities, and conference room.

    1305 Dadrian Professional Park, Godfrey, IL 62035
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    Visible Retail/Office Center For Rent
    $1,800 / Mo
    1,685 SF

    Visible Retail/Office Center For Rent

    Retail/office space with easy access and ample parking available for rent.

    2600 State St, Alton, IL 62002
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    Move-in Ready Office Suites
    $730 / Mo

    Move-in Ready Office Suites

    Office suites with private offices, bathrooms, and reception area.

    1352 Dadrian Prof Park Dr, Godfrey, IL 62035
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    Nameoki Road Office Space
    $10 SF/Yr
    25,696 SF

    Nameoki Road Office Space

    Granite City, IL Office Building - 15,500 SF Available

    3675 Nameoki Rd, Granite City, IL 62040
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    Collinsville Creative Office Space
    $18 SF/Yr
    18,310 SF

    Collinsville Creative Office Space

    6,223 SF Available in Class A Building

    1606 Eastport Plaza Dr, Collinsville, IL 62234
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    Mark Twain Plaza II Office Space
    $24 SF/Yr
    45,587 SF

    Mark Twain Plaza II Office Space

    Edwardsville, IL: Modern Office Suites Available

    103 Vandalia St, Edwardsville, IL 62025
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    Troy Office Complex: 11,900 SF
    $14 SF/Yr
    11,900 SF

    Troy Office Complex: 11,900 SF

    Three buildings, flexible suites, prime location.

    505 Buckeye Dr, Troy, IL 62294
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    Edwardsville Office Space Available
    $9 SF/Yr
    6,249 SF

    Edwardsville Office Space Available

    Flexible Offices, Coworking & More

    101 Vandalia St, Edwardsville, IL 62025
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    Collinsville Office Space for Lease
    $9 SF/Yr
    10,896 SF

    Collinsville Office Space for Lease

    Three Suites Available, Prime Location

    100 Regency Ctr, Collinsville, IL 62234
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    Godfrey, IL Office Space
    $9 SF/Yr
    96,921 SF

    Godfrey, IL Office Space

    Multiple suites, 1,104-6,301 sq ft.

    5771 Godfrey Rd, Godfrey, IL 62035
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    Office Space Near Interstate Access
    $695 / Mo
    575 SF

    Office Space Near Interstate Access

    Office space with lighted signage and easy interstate access.

    535 Edwardsville Rd, Troy, IL 62294
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    Edwardsville Office/Retail Suites Available
    $25 SF/Yr
    2,720 SF

    Edwardsville Office/Retail Suites Available

    Class A office/retail suites available in mixed-use development.

    1001-1010 Enclave Blvd, Edwardsville, IL
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    Professionally Managed Office Space
    $12 SF/Yr
    800 SF

    Professionally Managed Office Space

    Well-maintained office space in Maryville, IL, near major interstates.

    6201 W Main St, Maryville, IL 62062
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    Madison County, IL Office space Leasing Opportunities Market Analysis

    Explore Office space leasing options in Madison County, IL with 58 listings featured on our commercial real estate exchange. The current inventory includes 20,988,756,252 square feet of properties with an estimated lease value of $1,113 /Mo.

    Estimated lease rates for Office space in Madison County, IL begin at $3 SF/Yr, with an average of $34 SF/Yr and extend to $531 /Mo.
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    Office space by market

    Browse Office space for Lease Near Madison, IL

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