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    Simpsonville, SC Office Properties & Spaces for Sale

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    Columbia, SC Greenville, SC Aiken, SC
    9 results
    Professional Office Space in Simpsonville
    $425,000
    0.49 Acres

    Professional Office Space in Simpsonville

    107 Hillcrest Avenue, Simpsonville, SC 29681

    Adaptable office space near downtown Simpsonville and Fairview Road.

    • Prime location minutes from downtown Simpsonville, Fairview Road, and I‑385.
    • Flexible, efficient 1,844 sq ft layout suitable for various professional services.
    • Split configuration allows for two independent office operations with a shared break room.
    • Located in an area with steady commercial and residential growth.
    • Ample parking and straightforward access.
    Updated: Apr 2
    View details
    Charming Updated Office in Simpsonville
    Contact for pricing
    0.37 Acres

    Charming Updated Office in Simpsonville

    312 S Main Street, Simpsonville, SC 29681

    Prime location in Historic Downtown Simpsonville with rustic charm.

    • Prime location in Historic Downtown Simpsonville with excellent visibility.
    • Five potential offices, including one convertible to a conference room.
    • Elegantly finished reception area.
    • Full kitchen and full bathroom.
    • Ample parking with approximately 12–14 spaces.
    Updated: Feb 5
    View details
    Office Space in Simpsonville, SC
    Contact for pricing
    0.18 Acres

    Office Space in Simpsonville, SC

    Office property for sale in Simpsonville, South Carolina.

    131 SE Main Street, Simpsonville, SC 29681
    View details
    Professional Office Space in Simpsonville
    $425,000
    1,844 SF

    Professional Office Space in Simpsonville

    Adaptable 1,844 sq ft office near downtown Simpsonville.

    117 Hillcrest Avenue, Simpsonville, SC 29681
    View details
    Historic Mill Office Space Available
    Contact for pricing
    8,082 SF

    Historic Mill Office Space Available

    Office space in a renovated historic textile mill.

    300 S St, Simpsonville, SC
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    Main Street Commercial Opportunity
    $750,000
    1.42 Acres

    Main Street Commercial Opportunity

    Property with high visibility and development potential on 1.42 acres.

    1306 NE Main St, Simpsonville, SC
    View details
    Highway Frontage Property For Sale
    $550,000
    0.77 Acres

    Highway Frontage Property For Sale

    Versatile property with highway frontage, ideal for retail or office.

    1304 NE Main St, Simpsonville, SC
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    Versatile Commercial Property For Sale
    $725,000
    2,200 SF

    Versatile Commercial Property For Sale

    Adaptable commercial space with high visibility and convenient highway access.

    1306 NE Main St, Simpsonville, SC 29861
    View details
    Simpsonville Commercial Building For Sale
    $3,995,000
    24,000 SF

    Simpsonville Commercial Building For Sale

    24,000 SF building in Simpsonville, SC, renovated in 2013.

    313 N Main St, Simpsonville, SC 29681
    View details
    Based on your search, we've compiled 165 Potential Opportunities for your consideration. Besides 9 Active listings in Simpsonville, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 148 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Multi-Tenant Office Building For Sale
    $1,100,500
    5,000 SF

    Multi-Tenant Office Building For Sale

    Multi-tenant office building in Mauldin, SC, for sale.

    501 West Butler Road, Greenville, SC 29607
    View details
    Two Office Buildings For Sale
    $299,000
    1,800 SF

    Two Office Buildings For Sale

    Two-story office buildings in master-planned park, ideal for investors.

    102 Renaissance Cir, Mauldin, SC 29662
    View details
    Mauldin Office Building For Sale
    $299,000
    1,800 SF

    Mauldin Office Building For Sale

    Office building with private offices, conference room, and break area.

    108 Renaissance Cir, Mauldin, SC
    View details
    Two Greenville Office Buildings For Sale
    $2,750,000
    16,778 SF

    Two Greenville Office Buildings For Sale

    Two office buildings with excellent visibility near downtown Greenville.

    429 N Main St, Greenville, SC
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Simpsonville Commercial Land Opportunity
    $4,750,000
    15.60 Acres

    Simpsonville Commercial Land Opportunity

    15+ acres of commercial land near Fairview Road corridors.

    602 Harrison Bridge Road, Simpsonville, SC 29680
    View details
    Simpsonville Commercial Site Available
    $873,910
    2.81 Acres

    Simpsonville Commercial Site Available

    2.81 acre commercial site in Simpsonville, South Carolina.

    Harrison Bridge Road, Simpsonville, SC 29680
    View details
    Mauldin Commercial Site For Sale
    $200,000
    1.00 Acre

    Mauldin Commercial Site For Sale

    1+ acre lot approved for medical offices in growing area.

    Corn and Miller Road, Mauldin, SC 29607
    View details
    Prime Commercial Corner Lot Available
    $200,000
    1.00 Acre

    Prime Commercial Corner Lot Available

    1+ acre corner lot in rapidly growing Mauldin, SC.

    Corn and Miller Road, Mauldin, SC 29607
    View details

    Explore Off-Market Properties in Simpsonville, SC

    Consider similar Off-Market properties in Simpsonville, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    25 Holly Ctr Way

    25 Holly Ctr Way

    RADIO OR TV STATION • 1.73 Acres
    Value Estimation by Request
    25 Holly Ctr Way, Simpsonville, SC 29681-6819
    View details
    306 Hwy 14

    306 Hwy 14

    MEDICAL BUILDING • 0.08 Acres
    Value Estimation
    $890,000
    306 Hwy 14, Simpsonville, SC 29681-6054
    View details
    433 Main St

    433 Main St

    OFFICE BUILDING • 1.30 Acres
    Value Estimation
    $2,795,000
    433 Main St, Simpsonville, SC 29681-2669
    View details
    100 Woodruff Pl Cir

    100 Woodruff Pl Cir

    DENTAL BUILDING • 0.06 Acres
    Value Estimation
    $1,400,000
    100 Woodruff Pl Cir, Simpsonville, SC 29681-3672
    View details
    210 Trade St

    210 Trade St

    OFFICE BUILDING • 2,454 SF
    Value Estimation
    $775,000
    210 Trade St, Simpsonville, SC 29681-2632
    View details
    2814 Woodruff Rd

    2814 Woodruff Rd

    MEDICAL BUILDING • 1,534 SF
    Value Estimation
    $4,010,000
    2814 Woodruff Rd, Simpsonville, SC 29681-4806
    View details
    101 Main St

    101 Main St

    OFFICE BUILDING • 0.06 Acres
    Value Estimation
    $1,190,000
    101 Main St, Simpsonville, SC 29681
    View details
    3930 Grandview Dr

    3930 Grandview Dr

    MEDICAL BUILDING • 0.84 Acres
    Value Estimation
    $1,760,000
    3930 Grandview Dr, Simpsonville, SC 29680-3163
    View details
    304 Main St

    304 Main St

    OFFICE BUILDING • 0.70 Acres
    Value Estimation
    $1,950,000
    304 Main St, Simpsonville, SC 29681-2606
    View details
    140 Neely Fry Rda

    140 Neely Fry Rda

    OFFICE BUILDING • 1,529 SF
    Value Estimation by Request
    140 Neely Fry Rda, Simpsonville, SC 29680-6137
    View details
    805 Georgia Rd

    805 Georgia Rd

    MEDICAL BUILDING • 1,831 SF
    Value Estimation
    $2,875,000
    805 Georgia Rd, Simpsonville, SC 29680-6213
    View details
    422 Scuffletown Rd

    422 Scuffletown Rd

    OFFICE BUILDING • 1,398 SF
    Value Estimation
    $575,000
    422 Scuffletown Rd, Simpsonville, SC 29681-7206
    View details
    330 Harrison Brg Rd

    330 Harrison Brg Rd

    OFFICE BUILDING • 0.87 Acres
    Value Estimation
    $2,180,000
    330 Harrison Brg Rd, Simpsonville, SC 29680-7133
    View details
    883 Main St

    883 Main St

    OFFICE BUILDING • 0.40 Acres
    Value Estimation
    $745,000
    883 Main St, Simpsonville, SC 29681-2051
    View details
    219 Batesville Rd

    219 Batesville Rd

    DENTAL BUILDING • 0.12 Acres
    Value Estimation
    $1,300,000
    219 Batesville Rd, Simpsonville, SC 29681-4816
    View details

    Simpsonville, SC Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 157 office properties & spaces for sale in Simpsonville, SC, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 4,813,390 square feet of properties for sale, with an estimated market value of $70,425,000.

    Sale prices for office spaces in Simpsonville, SC start at $60,000, averaging $978,125, and reaching up to $5,540,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Office properties & Spaces for Sale Near Simpsonville, SC

    Popular Searches in Simpsonville, SC

    Most Searched ZIP Codes in Simpsonville, SC

    • 29681
    • 29861

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