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    Simpsonville, SC
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    Simpsonville, SC Office Spaces for Sale

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    Greenville, SC Fountain Inn, SC Mauldin, SC
    6 results
    Professional Office Space in Simpsonville
    $425,000
    1,844 SF
    Professional Office Space in Simpsonville

    117 Hillcrest Avenue, Simpsonville, SC 29681

    Adaptable 1,844 sq ft office near downtown Simpsonville.
    • Prime location minutes from downtown Simpsonville, Fairview Road commercial corridor, and I‑385, offering excellent accessibility.
    • Flexible, efficient 1,844 sq ft layout suitable for various professional uses.
    • Split configuration allows for two independent office operations with a shared break room.
    • Located in a rapidly growing area with increasing population, new residential communities, and expanding commercial services.
    • Ample parking and straightforward access for clients and employees.
    Updated: Feb 10
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    Historic Mill Office Space Available
    Contact for pricing
    8,082 SF
    Historic Mill Office Space Available

    300 S St, Simpsonville, SC

    Office space in a renovated historic textile mill.
    • Located in the historic Cotton Mill Place, a renovated textile mill blending historic charm with modern amenities.
    • Large open concept first floor (±7,068 sq ft) suitable for various uses.
    • Total available space of ±8,082 sq ft.
    • Mezzanine level (±1,014 sq ft) includes three private offices and a breakroom.
    • Includes a front desk, three individual private rooms, and two restrooms on the first floor.
    Updated: Nov 24, 2025
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    Main Street Commercial Opportunity
    $750,000
    1.42 Acres
    Main Street Commercial Opportunity

    Property with high visibility and development potential on 1.42 acres.

    1306 NE Main St, Simpsonville, SC

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    Highway Frontage Property For Sale
    $550,000
    0.77 Acres
    Highway Frontage Property For Sale

    Versatile property with highway frontage, ideal for retail or office.

    1304 NE Main St, Simpsonville, SC

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    Simpsonville Commercial Building For Sale
    $3,995,000
    24,000 SF
    Simpsonville Commercial Building For Sale

    24,000 SF building in Simpsonville, SC, renovated in 2013.

    313 N Main St, Simpsonville, SC 29681

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    Versatile Commercial Property For Sale
    $725,000
    2,200 SF
    Versatile Commercial Property For Sale

    Adaptable commercial space with high visibility and convenient highway access.

    1306 NE Main St, Simpsonville, SC 29861

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 6 Active listings in Simpsonville, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 66 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Multi-Tenant Office Building For Sale
    $1,100,500
    5,000 SF
    Multi-Tenant Office Building For Sale

    Multi-tenant office building in Mauldin, SC, for sale.

    501 West Butler Road, Greenville, SC 29607

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    Two Greenville Office Buildings For Sale
    $2,750,000
    16,778 SF
    Two Greenville Office Buildings For Sale

    Two office buildings with excellent visibility near downtown Greenville.

    429 N Main St, Greenville, SC

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    Mauldin Office Building For Sale
    $299,000
    1,800 SF
    Mauldin Office Building For Sale

    Office building with private offices, conference room, and break area.

    108 Renaissance Cir, Mauldin, SC

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    Two Office Buildings For Sale
    $299,000
    1,800 SF
    Two Office Buildings For Sale

    Two-story office buildings in master-planned park, ideal for investors.

    102 Renaissance Cir, Mauldin, SC 29662

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Simpsonville Commercial Land Opportunity
    $873,910
    2.81 Acres
    Simpsonville Commercial Land Opportunity

    2.81 acres available in Simpsonville's Innovation District.

    Harrison Bridge Road, Simpsonville, SC 29680

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    Simpsonville Commercial Land For Sale
    $4,750,000
    15.60 Acres
    Simpsonville Commercial Land For Sale

    15+ acres suitable for commercial development near Fairview Road.

    602 Harrison Bridge Road, Simpsonville, SC 29680

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    Prime Corner Lot in Mauldin
    $200,000
    1.00 Acre
    Prime Corner Lot in Mauldin

    Highly visible commercial land with development potential in a growing area.

    Corn and Miller Road, Mauldin, SC 29607

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    Mauldin Commercial Lot For Sale
    $200,000
    1.00 Acre
    Mauldin Commercial Lot For Sale

    One-acre commercial lot in a rapidly growing Mauldin area.

    Corn and Miller Road, Mauldin, SC 29607

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    Off-Market Properties in Simpsonville, SC

    Consider similar Off-Market properties in Simpsonville, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    25 Holly Ctr Way
    RADIO OR TV STATION
    Lot: 1.73 Acres
    Value Estimation by Request

    25 Holly Ctr Way, Simpsonville, SC 29681-6819

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    306 Hwy 14
    MEDICAL BUILDING
    Lot: 0.08 Acres
    Estimated value
    $890,000

    306 Hwy 14, Simpsonville, SC 29681-6054

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    433 Main St
    OFFICE BUILDING
    Lot: 1.30 Acres
    Estimated value
    $2,795,000

    433 Main St, Simpsonville, SC 29681-2669

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    100 Woodruff Pl Cir
    DENTAL BUILDING
    Lot: 0.06 Acres
    Estimated value
    $1,400,000

    100 Woodruff Pl Cir, Simpsonville, SC 29681-3672

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    210 Trade St
    OFFICE BUILDING
    2,454 SF Lot: 0.16 Acres
    Estimated value
    $775,000

    210 Trade St, Simpsonville, SC 29681-2632

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    2814 Woodruff Rd
    MEDICAL BUILDING
    1,534 SF Lot: 3.71 Acres
    Estimated value
    $4,010,000

    2814 Woodruff Rd, Simpsonville, SC 29681-4806

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    101 Main St
    OFFICE BUILDING
    Lot: 0.06 Acres
    Estimated value
    $1,190,000

    101 Main St, Simpsonville, SC 29681

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    3930 Grandview Dr
    MEDICAL BUILDING
    Lot: 0.84 Acres
    Estimated value
    $1,760,000

    3930 Grandview Dr, Simpsonville, SC 29680-3163

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    304 Main St
    OFFICE BUILDING
    Lot: 0.70 Acres
    Estimated value
    $1,950,000

    304 Main St, Simpsonville, SC 29681-2606

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    140 Neely Fry Rda
    OFFICE BUILDING
    1,529 SF Lot: 0.80 Acres
    Value Estimation by Request

    140 Neely Fry Rda, Simpsonville, SC 29680-6137

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    805 Georgia Rd
    MEDICAL BUILDING
    1,831 SF Lot: 0.70 Acres
    Estimated value
    $2,875,000

    805 Georgia Rd, Simpsonville, SC 29680-6213

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    422 Scuffletown Rd
    OFFICE BUILDING
    1,398 SF Lot: 17.50 Acres
    Estimated value
    $575,000

    422 Scuffletown Rd, Simpsonville, SC 29681-7206

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    330 Harrison Brg Rd
    OFFICE BUILDING
    Lot: 0.87 Acres
    Estimated value
    $2,180,000

    330 Harrison Brg Rd, Simpsonville, SC 29680-7133

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    883 Main St
    OFFICE BUILDING
    Lot: 0.40 Acres
    Estimated value
    $745,000

    883 Main St, Simpsonville, SC 29681-2051

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    219 Batesville Rd
    DENTAL BUILDING
    Lot: 0.12 Acres
    Estimated value
    $1,300,000

    219 Batesville Rd, Simpsonville, SC 29681-4816

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    425 Main St
    OFFICE BUILDING
    Lot: 0.03 Acres
    Value Estimation by Request

    425 Main St, Simpsonville, SC 29681

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    273 Harrison Brg Rd
    MEDICAL BUILDING
    Lot: 1.35 Acres
    Estimated value
    $4,870,000

    273 Harrison Brg Rd, Simpsonville, SC 29680-7132

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    312 Harrison Brg Rd
    MEDICAL BUILDING
    Lot: 1.94 Acres
    Estimated value
    $4,450,000

    312 Harrison Brg Rd, Simpsonville, SC 29680-7133

    View details

    Simpsonville, SC Office Spaces Investment Opportunities Market Analysis

    Explore 72 office spaces for sale in Simpsonville, SC, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 28,044 square feet of properties for sale, with an estimated market value of $5,145,000.

    Sale prices for office spaces in Simpsonville, SC start at $425,000, averaging $1,715,000, and reaching up to $3,995,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Office Units 11
    Medical Office Space 1

    Demographics Overview

    Population 103K
    Population Growth (5Y) +13.4%
    Median Household Income $99,967
    College Educated 58.9%

    High-Yield Neighborhoods for Investment

    Identify Simpsonville submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    North Augusta $725K
    Simpsonville $2.2M

    Taxes & Financing

    Average Loan-to-Value 65.0%

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