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Simpsonville, SC Office Spaces for Sale

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Greenville, SC Fountain Inn, SC Mauldin, SC Piedmont, SC Greer, SC Woodruff, SC Pelzer, SC Gray Court, SC
6 properties
Historic Creative Workspace
Updated: Jun 25
Historic Creative Workspace

300 South St, Simpsonville, SC 29681

$1,750,000
8,082 sqft
±8,082 SF total property
±7,068 SF first‑floor open‑concept layout
±1,014 SF mezzanine with three private offices and a breakroom
Three individual private rooms plus two restrooms on the first floor
Outdoor patio space
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Simpsonville Commercial Building For Sale
Updated: Mar 27
Simpsonville Commercial Building For Sale

313 N Main Street, Simpsonville, SC 29681

$3,995,000
24,000 sqft
24,000 SF building in Simpsonville
Renovated in 2013 and meticulously maintained
C2 zoning designation allows for versatile usage
High visibility location in the heart of Simpsonville
Easy access
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Medical Office Space with Existing Buildout
Medical Office Space with Existing Buildout

717 NE Main St, Simpsonville, SC 29681

Contact for pricing
3,000 sqft

Existing chiropractic-office configuration supports continued professional use or conversion for legal and accounting services.

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Realmo Analytics Monitor Off-market properties and contact owners who are ready to sell. Many signals applied to make quality leads for you. Get Leads
Second-Generation Medical Office
Second-Generation Medical Office

35 Ray E Talley Ct, Simpsonville, SC 29680

Contact for pricing
7,880 sqft

Well-maintained medical and office space in Simpsonville’s retail corridor near I-385 access.

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Office Unit with Laydown Yard
Office Unit with Laydown Yard

205 New Harrison Bridge Rd, Simpsonville, SC 29680

Contact for pricing
1,425 sqft

Office space paired with a dedicated outdoor storage and staging area.

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Versatile Commercial Property For Sale
Versatile Commercial Property For Sale

1306 NE Main St, Simpsonville, SC 29861

Contact for pricing
2,200 sqft

Adaptable commercial space with high visibility and convenient highway access.

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Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 6 Active listings in Simpsonville, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 66 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Single-Level Brick Medical Office
Single-Level Brick Medical Office

203 S Weston Street, Fountain Inn, SC 29644

$1,500,000
0.59 AC lot

C-1 zoning, an included adjacent lot, and a detached brick outbuilding support flexible medical-office use.

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Two Office Buildings For Sale
Two Office Buildings For Sale

102 Renaissance Cir, Mauldin, SC 29662

$299,000
1,800 sqft

Two-story office buildings in master-planned park, ideal for investors.

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Retail/Office Opportunity in Fountain Inn
Retail/Office Opportunity in Fountain Inn

129 North Main Street, Fountain Inn, SC 29644

Contact for pricing
13,421 sqft

Retail/office space for sale in downtown Fountain Inn, SC.

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Mauldin Office Building For Sale
Mauldin Office Building For Sale

108 Renaissance Cir, Mauldin, SC

Contact for pricing
1,800 sqft 0.08 AC lot

Office building with private offices, conference room, and break area.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Innovation District Commercial Land
Innovation District Commercial Land

Harrison Bridge Road, Simpsonville, SC 29680

$873,910
2.81 AC lot

Commercial land with available utilities near the Harrison Bridge Road and Fairview Road intersection.

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C-3 Commercial Land
C-3 Commercial Land

Old Piedmont Highway, Greenville, SC 29605

$50,000
0.60 AC lot

C-3-zoned commercial land with public water service.

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Haywood Road Land Opportunity
Haywood Road Land Opportunity

7 Alford Ct, Greenville, SC 29607

$148,900

Land near Haywood Road, suitable for office or residential development.

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Downtown Greenville Lot For Sale
Downtown Greenville Lot For Sale

110 Wakefield St, Greenville, SC 29601

$450,000

Prime lot near Augusta Road, County Square, and Fluor Field.

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Off-Market Properties in Simpsonville, SC

Consider similar Off-Market properties in Simpsonville, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

25 Holly Ctr Way
RADIO OR TV STATION

25 Holly Ctr Way, Simpsonville, SC 29681-6819

Estimated value:
$220,000
1.73 AC lot
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306 Hwy 14
MEDICAL BUILDING

306 Hwy 14, Simpsonville, SC 29681-6054

Estimated value:
$890,000
0.08 AC lot
View details
433 Main St
OFFICE BUILDING

433 Main St, Simpsonville, SC 29681-2669

Estimated value:
$2,560,000
1.30 AC lot
View details
100 Woodruff Pl Cir
DENTAL BUILDING

100 Woodruff Pl Cir, Simpsonville, SC 29681-3672

Estimated value:
$1,280,000
0.06 AC lot
View details
210 Trade St
OFFICE BUILDING

210 Trade St, Simpsonville, SC 29681-2632

Estimated value:
$745,000
2,454 sqft 0.16 AC lot
View details
2814 Woodruff Rd
MEDICAL BUILDING

2814 Woodruff Rd, Simpsonville, SC 29681-4806

Estimated value:
$3,695,000
1,534 sqft 3.71 AC lot
View details
101 Main St
OFFICE BUILDING

101 Main St, Simpsonville, SC 29681

Estimated value:
$1,025,000
0.06 AC lot
View details
3930 Grandview Dr
MEDICAL BUILDING

3930 Grandview Dr, Simpsonville, SC 29680-3163

Estimated value:
$1,760,000
0.84 AC lot
View details
304 Main St
OFFICE BUILDING

304 Main St, Simpsonville, SC 29681-2606

Estimated value:
$1,950,000
0.70 AC lot
View details
140 Neely Fry Rda
OFFICE BUILDING

140 Neely Fry Rda, Simpsonville, SC 29680-6137

Estimated value:
$120,000
1,529 sqft 0.80 AC lot
View details
805 Georgia Rd
MEDICAL BUILDING

805 Georgia Rd, Simpsonville, SC 29680-6213

Estimated value:
$2,875,000
1,831 sqft 0.70 AC lot
View details
422 Scuffletown Rd
OFFICE BUILDING

422 Scuffletown Rd, Simpsonville, SC 29681-7206

Estimated value:
$575,000
1,398 sqft 17.50 AC lot
View details
330 Harrison Brg Rd
OFFICE BUILDING

330 Harrison Brg Rd, Simpsonville, SC 29680-7133

Estimated value:
$2,180,000
0.87 AC lot
View details
883 Main St
OFFICE BUILDING

883 Main St, Simpsonville, SC 29681-2051

Estimated value:
$745,000
0.40 AC lot
View details
219 Batesville Rd
DENTAL BUILDING

219 Batesville Rd, Simpsonville, SC 29681-4816

Estimated value:
$1,300,000
0.12 AC lot
View details
425 Main St
OFFICE BUILDING

425 Main St, Simpsonville, SC 29681

Estimated value:
$275,000
0.03 AC lot
View details
273 Harrison Brg Rd
MEDICAL BUILDING

273 Harrison Brg Rd, Simpsonville, SC 29680-7132

Estimated value:
$4,510,000
1.35 AC lot
View details
312 Harrison Brg Rd
MEDICAL BUILDING

312 Harrison Brg Rd, Simpsonville, SC 29680-7133

Estimated value:
$4,245,000
1.94 AC lot
View details

Simpsonville, SC Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in Simpsonville, SC, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 46,587 square feet of properties for sale, with an estimated market value of $5,745,000.

Sale prices for office properties in Simpsonville, SC start at $1,750,000, averaging $2,872,500, and reaching up to $3,995,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 7
Medical Office Space 3
Creative space 1
Office buildings 1

Demographics Overview

Population 103K
Population Growth (5Y) +13.4%
Median Household Income $99,967
College Educated 58.9%

High-Yield Neighborhoods for Investment

Identify Simpsonville submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
29681 $2.9M

Taxes & Financing

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Greenville County

New Delisted

Total CRE Inventory on Market (SF)

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