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Simpsonville, SC Office Spaces for Sale

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Greenville, SC Fountain Inn, SC Mauldin, SC Piedmont, SC Greer, SC Woodruff, SC Pelzer, SC Gray Court, SC
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Simpsonville Commercial Building For Sale
Updated: Mar 27
Simpsonville Commercial Building For Sale

313 N Main Street, Simpsonville, SC 29681

$3,995,000
24,000 sqft
24,000 SF building in Simpsonville
Renovated in 2013 and meticulously maintained
C2 zoning designation allows for versatile usage
High visibility location in the heart of Simpsonville
Easy access
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This listing looks promising.

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313 N Main Street, Simpsonville, SC 29681

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Historic Creative Workspace
Updated: Jun 25
Historic Creative Workspace

300 South St, Simpsonville, SC 29681

$1,750,000
8,082 sqft
±8,082 SF total property
±7,068 SF first‑floor open‑concept layout
±1,014 SF mezzanine with three private offices and a breakroom
Three individual private rooms plus two restrooms on the first floor
Outdoor patio space
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Second-Generation Medical Office
Second-Generation Medical Office

35 Ray E Talley Ct, Simpsonville, SC 29680

Contact for pricing
7,880 sqft

Well-maintained medical and office space in Simpsonville’s retail corridor near I-385 access.

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Office Building with Metal Roof
Office Building with Metal Roof

717 NE Main St, Simpsonville, SC 29681

$499,000

Office property featuring a metal roof and two existing HVAC systems.

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Mixed-Use Building
Mixed-Use Building

107 South Maple Street, Simpsonville, SC 29681

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2,057 sqft 0.41 AC lot

Office and retail use potential is supported by on-site parking and additional street parking.

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Versatile Commercial Property For Sale
Versatile Commercial Property For Sale

1306 NE Main St, Simpsonville, SC 29861

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2,200 sqft

Adaptable commercial space with high visibility and convenient highway access.

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Office Unit with Laydown Yard
Office Unit with Laydown Yard

205 New Harrison Bridge Rd, Simpsonville, SC 29680

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1,425 sqft

Office space paired with a dedicated outdoor storage and staging area.

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New Retail Space with End Caps
New Retail Space with End Caps

00 Scuffletown Road, Simpsonville, SC 29681

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Planned retail space offers flexible suite configurations for commercial users.

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Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 8 Active listings in Simpsonville, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 64 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Retail/Office Opportunity in Fountain Inn
Retail/Office Opportunity in Fountain Inn

129 North Main Street, Fountain Inn, SC 29644

Contact for pricing
13,421 sqft

Retail/office space for sale in downtown Fountain Inn, SC.

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Office Suite with 2 Units
Office Suite with 2 Units

140 Bridges Rd, Units F&G, Mauldin, SC 29662

Contact for pricing
4,856 sqft

Office space for sale featuring Units F and G within a single commercial building.

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Freestanding Office Building
Freestanding Office Building

16 West Point Boulevard, Mauldin, SC 29662

$395,000

Standalone office property with dual-street access and C-2 zoning near major regional roads.

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Downtown Mixed-Use Office and Retail
Downtown Mixed-Use Office and Retail

214 S Main Street, Fountain Inn, SC 29644

Contact for pricing

Versatile C-1 zoned suite with a lobby, four offices, kitchen, and restrooms, plus extra back-alley parking.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Simpsonville Commercial Land Opportunity
Simpsonville Commercial Land Opportunity

Harrison Bridge Road, Simpsonville, SC 29680

$873,910
2.81 AC lot

2.81 acres available in Simpsonville's Innovation District.

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Commercial Land with Public Water
Commercial Land with Public Water

602 Harrison Bridge Road, Simpsonville, SC 29680

$4,750,000
15.60 AC lot

Commercial land offering public water access near Fairview Road shopping and restaurants.

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Cleared C-2 Commercial Land
Cleared C-2 Commercial Land

Scuffletown Road, Simpsonville, SC 29681

$1,700,000
7.00 AC lot

Level, cleared site with public water near Woodruff Road.

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Cleared Commercial Land
Cleared Commercial Land

Scuffletown Road, Simpsonville, SC 29681

$1,700,000
7.00 AC lot

Level, cleared acreage with C-2 zoning and public water service.

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Off-Market Properties in Simpsonville, SC

Consider similar Off-Market properties in Simpsonville, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

25 Holly Ctr Way
RADIO OR TV STATION

25 Holly Ctr Way, Simpsonville, SC 29681-6819

$220,000
Estimated value
1.73 AC lot
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306 Hwy 14
MEDICAL BUILDING

306 Hwy 14, Simpsonville, SC 29681-6054

$890,000
Estimated value
0.08 AC lot
View details
433 Main St
OFFICE BUILDING

433 Main St, Simpsonville, SC 29681-2669

$2,560,000
Estimated value
1.30 AC lot
View details
100 Woodruff Pl Cir
DENTAL BUILDING

100 Woodruff Pl Cir, Simpsonville, SC 29681-3672

$1,280,000
Estimated value
0.06 AC lot
View details
210 Trade St
OFFICE BUILDING

210 Trade St, Simpsonville, SC 29681-2632

$745,000
Estimated value
2,454 sqft 0.16 AC lot
View details
2814 Woodruff Rd
MEDICAL BUILDING

2814 Woodruff Rd, Simpsonville, SC 29681-4806

$3,695,000
Estimated value
1,534 sqft 3.71 AC lot
View details
101 Main St
OFFICE BUILDING

101 Main St, Simpsonville, SC 29681

$1,025,000
Estimated value
0.06 AC lot
View details
3930 Grandview Dr
MEDICAL BUILDING

3930 Grandview Dr, Simpsonville, SC 29680-3163

$1,760,000
Estimated value
0.84 AC lot
View details
304 Main St
OFFICE BUILDING

304 Main St, Simpsonville, SC 29681-2606

$1,950,000
Estimated value
0.70 AC lot
View details
140 Neely Fry Rda
OFFICE BUILDING

140 Neely Fry Rda, Simpsonville, SC 29680-6137

$120,000
Estimated value
1,529 sqft 0.80 AC lot
View details
805 Georgia Rd
MEDICAL BUILDING

805 Georgia Rd, Simpsonville, SC 29680-6213

$2,875,000
Estimated value
1,831 sqft 0.70 AC lot
View details
422 Scuffletown Rd
OFFICE BUILDING

422 Scuffletown Rd, Simpsonville, SC 29681-7206

$575,000
Estimated value
1,398 sqft 17.50 AC lot
View details
330 Harrison Brg Rd
OFFICE BUILDING

330 Harrison Brg Rd, Simpsonville, SC 29680-7133

$2,180,000
Estimated value
0.87 AC lot
View details
883 Main St
OFFICE BUILDING

883 Main St, Simpsonville, SC 29681-2051

$745,000
Estimated value
0.40 AC lot
View details
219 Batesville Rd
DENTAL BUILDING

219 Batesville Rd, Simpsonville, SC 29681-4816

$1,300,000
Estimated value
0.12 AC lot
View details
425 Main St
OFFICE BUILDING

425 Main St, Simpsonville, SC 29681

$275,000
Estimated value
0.03 AC lot
View details

Simpsonville, SC Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in Simpsonville, SC, showcased through 8 active listings on our real estate platform. These investment opportunities span a total of 45,644 square feet of properties for sale, with an estimated market value of $6,244,000.

Sale prices for office spaces in Simpsonville, SC start at $499,000, averaging $2,081,333, and reaching up to $3,995,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 14
Medical Office Space 6
Office buildings 4
Creative space 1

Demographics Overview

Population 103K
Population Growth (5Y) +13.4%
Median Household Income $99,967
College Educated 58.9%

Taxes & Financing

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Greenville County

New Delisted

Total CRE Inventory on Market (SF)

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