Littleton, CO Office Spaces for sale

Updated: Oct 5

Medical Office Building with Multiple Suites

5401 S Prince Street, Littleton, CO 80120

$1,590,000

5,778 sqft 0.33 AC lot

5,778 SF professional and medical office building on 0.33 acres
12 suites ranging from approximately 138 to 848 SF
Approximately 709 SF available
84% leased on short‑term, full‑service gross leases
DMU 3 zoning within the Littleton Downtown Development Authority

View details

Updated: Apr 24

Turnkey Medical Office Building

20 W Dry Creek Circle, Littleton, CO 80120

$3,750,000

14,846 sqft 2.00 AC lot

Turnkey 14,846 SF medical office building (MOB) delivered vacant for immediate owner‑user occupancy.
$1.5M in 2022 upgrades; fully modernized.
Located in Littleton’s premier healthcare corridor near C‑470, South Broadway, and Littleton Adventist Hospital.
Situated on a two‑acre site with 60 surface parking spaces.
Multiple direct‑entry suites offer superior functionality.

View details

Modernized Medical Office Building

20 W Dry Creek, Littleton, CO 80120

$3,750,000

14,846 sqft 2.00 AC lot

Vacant medical office property with direct-entry suites and on-site surface parking.

View details

Realmo Analytics Monitor Off-market properties and contact owners who are ready to sell. Many signals applied to make quality leads for you. Get Leads

Office Condo with Private Reception

B-13976 W Bowles Ave, Littleton, CO 80127

$357,740

1,276 sqft

Thoughtfully laid-out suite with private reception, four offices, private restroom, kitchenette, and Quantum Fiber connectivity.

View details

Littleton Medical/Office Building For Sale

7761 Shaffer Pkwy, Littleton, CO 80127

$4,750,000

30,447 sqft

30,447 SF medical/office building in Littleton, CO for sale.

View details

Historic Mixed-Use Main Street Building

2340 W Main St, Littleton, CO 80120

$750,000

1,742 sqft

Two-story downtown property combines leased ground-floor retail with adaptable upper-level space for residential or office conversion.

View details

Classic Littleton Office Building

709 W Littleton Boulevard, Littleton, CO 80120

$1,575,000

10,530 sqft

Three-level office building in revitalizing Littleton Boulevard area.

View details

Multi-Tenant Office Building

7800 S Elati Street, Littleton, CO 80120

Contact for pricing

26,835 sqft 1.22 AC lot

Three-story office property with four suites ready for lease and a layout centered on smaller offices.

View details

Ground-Level Office Condo Suite

7621 Shaffer Pkwy, Littleton, CO 80127

Contact for pricing

1,993 sqft

Ground-level office condo features two HVAC units, ADA restrooms, and a kitchenette with private main entrance.

View details

Historic Mixed-Use Live-Work Property

2606 West Alamo Avenue, Littleton, CO 80120

$1,375,000

4,942 sqft

Two downtown buildings combine retail, office, and flexible live-work potential.

View details

Live-Work Space with Rooftop Deck

5439 South Prince Street, Littleton, CO 80120

Contact for pricing

4,275 sqft

Vacant mixed-use property combines flexible office space with a refined residential loft and multiple outdoor areas.

View details

Freestanding Converted Office Building

1979 W Littleton Blvd, Littleton, CO 80120

Contact for pricing

3,320 sqft

Well-maintained office building with updated exterior paint and newly installed windows and exterior doors.

View details

Professional Office Building

5878 S Rapp St, Littleton, CO 80120

$2,800,000

Well-maintained office building with an open floorplan concept and flexibility to customize for new uses.

View details

Small Office Suite

1100 W Littleton Blvd, Littleton, CO 80120

Contact for pricing

1,019 sqft

Small office space with included desks, a conference table, and always-available parking.

View details

Littleton Office Space For Sale

1100 W Littleton Blvd, Littleton, CO

Contact for pricing

777 sqft

Remodeled office space near downtown Littleton and light rail.

View details

Second-Floor Remodeled Office Unit

1100 W Littleton Blvd, Littleton, CO 80120

Contact for pricing

777 sqft

Completely remodeled second-floor office with open bullpen and two private offices, move-in ready with HOA services included.

View details

Office Building in Business Park

8381 Southpark Ln, Littleton, CO 80120

Contact for pricing

17,792 sqft

Office building within the Southpark Business Centre, accessed from County Line Road and near major highway routes.

View details

Historic Live-Work Properties

2606-5765 W Alamo Ave, Littleton, CO 80120

Contact for pricing

4,942 sqft

Two historic-district properties offer flexible commercial, residential, and mixed-use possibilities in a walkable downtown setting.

View details

Remodeled Littleton Office Space

1100 W Littleton Blvd #210, Littleton, CO 80120

$135,000

Move-in ready office near Downtown Littleton and Light Rail.

View details

Flex Space Condo/Office/Warehouse

5361-5399 S Alkire Cir, Littleton, CO

Contact for pricing

4,244 sqft 3.42 AC lot

Condo units for sale or lease, from 4,000 SF.

View details

Mixed-Use Office and Retail Building

739 West Littleton Boulevard, Littleton, CO 80120

Contact for pricing

Flexible interior arrangement supports professional, medical, legal, financial, and other service-oriented operations.

View details

Office-Flex Warehouse Condos

5361-5399 S Alkire Cir, Littleton, CO 80127

Contact for pricing

2,550 sqft

Cold dark shell office-flex units with varying ceiling heights, plus drive-in and dock-high loading.

View details

Office-Flex Warehouse Condos

5361-5399 S Alkire Cir, Littleton, CO 80127

Contact for pricing

3,232 sqft

Cold dark shell office-flex and warehouse units with varying ceiling heights, plus drive-in doors and dock-high access.

View details

Ken Caryl Ranch Office Opportunity

10394 W Chatfield Ave, Littleton, CO 80127

Contact for pricing

5,500 sqft

Office space for sale in excellent southwest location.

View details

Littleton, CO Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in Littleton, CO, showcased through 28 active listings on our real estate platform. These investment opportunities span a total of 269,663 square feet of properties for sale, with an estimated market value of $20,832,740.

Sale prices for office properties in Littleton, CO start at $135,000, averaging $2,083,274, and reaching up to $4,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Neighborhood	Average Price
80120	$2M
80127	$2.5M

Neighborhood

Average Price

80120

$2M

80127

$2.5M