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Littleton, CO Medical Office Space for Lease

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11 results
Ken Caryl Business Center Suites
$19 SF/Yr
5,500 SF

Ken Caryl Business Center Suites

7610 - 7640 S Alkire Pl, Littleton, CO 80127

Office, medical, flex, and retail spaces available for lease.

  • Affordable lease rates at $19.50/SF Modified Gross.
  • Build‑to‑suit opportunity for Buildings 7630 & 7640.
  • Well‑located off C‑470 and W Ken Caryl Ave in Littleton, providing quick access to C‑470.
  • Suites available for professional office, medical office, high‑end flex, and quasi‑retail use.
  • Located in a dense retail corridor with numerous restaurants, banking, hotels, and shopping options.
Updated: Jan 27
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Littleton Medical Arts Building For Lease
$28 SF/Yr

Littleton Medical Arts Building For Lease

8340 Sangre de Cristo Rd., Littleton, CO 80127

Littleton Medical Arts Building For Lease

  • Recently updated by new owner in 2022
  • Motivated Landlord
  • Tenant improvement (TI) dollars available
  • Opportunity for building signage
Updated: May 19, 2025
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Medical Office Sublease Opportunity
Contact for pricing
7,430 SF

Medical Office Sublease Opportunity

Freestanding medical office building with ample parking available for sublease.

13351 W Bowles Ave, Littleton, CO
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Littleton Office Sublease Opportunity
$18 SF/Yr
1,500 SF

Littleton Office Sublease Opportunity

Office sublease with exam rooms, provider offices, and shared spaces.

7261 S Broadway, Littleton, CO
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Medical Office Space Available
Contact for pricing

Medical Office Space Available

Suburban medical office space with ample parking and strong demographics.

8340 Sangre De Cristo Rd, Littleton, CO 80127
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Medical Office Building For Lease
Contact for pricing
17,012 SF

Medical Office Building For Lease

Proposed medical office building with spaces available for lease.

7560 S Pierce St, Littleton, CO
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Modernized Medical and Professional Campus
Contact for pricing
4,259 SF

Modernized Medical and Professional Campus

Healthcare-ready property in Denver's southwest corridor near the Tech Center.

10184 W Belleview Ave, Littleton, CO 80127
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Retail Space for Neighborhood Uses
Contact for pricing

Retail Space for Neighborhood Uses

Retail spaces suitable for breweries, barbershops, fitness, and medical.

8250 W Coal Mine Ave, Littleton, CO 80123
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Littleton Office Space For Rent
$16 SF/Yr
3,866 SF

Littleton Office Space For Rent

Office space for lease near hospitals and shopping center.

801 W Mineral Ave, Littleton, CO
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Medical Office Space Available
$26 SF/Yr
2,045 SF

Medical Office Space Available

Medical office space near AdventHealth Littleton, 2045 square feet.

414 E Mineral Ave, Littleton, CO
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Redevelopment Opportunity in Littleton, Colorado
Contact for pricing
15,000 SF

Redevelopment Opportunity in Littleton, Colorado

Land and medical office space available for lease or purchase.

Ken Caryl Avenue & Pierce Street, Littleton, CO 80128
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Based on your search, we've compiled 26 Potential Opportunities for your consideration. Besides 11 Active listings in Littleton, CO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Explore Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Highlands Ranch Medical/Office Space
Contact for pricing

Highlands Ranch Medical/Office Space

Medical and office spaces available for lease in Highlands Ranch.

9135 South Ridgeline Boulevard, Highlands Ranch, CO 80129
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Hampden CenterEnglewood, CO 80110
$19 SF/Yr

Hampden CenterEnglewood, CO 80110

565 - 28,791 SF of Space Available

750 W Hampden Ave Englewood, CO 80110, Englewood, CO 80110
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Highlands Ranch Medical Office Space
Contact for pricing
7,976 SF

Highlands Ranch Medical Office Space

7,976 SF medical office space available for lease.

200 W County Line Rd, Highlands Ranch, CO
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Englewood Retail Space Available
Contact for pricing
2,600 SF

Englewood Retail Space Available

2,600 SF retail space with high visibility.

4989 S Broadway, Englewood, CO 80113
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Explore Similar Spaces for Sale in Littleton, CO

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Turnkey Medical Office Building
$3,750,000
14,846 SF

Turnkey Medical Office Building

Modernized 14,846 SF medical office in Littleton for sale.

20 W Dry Creek Circle, Littleton, CO 80120
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Multi-Tenant Office/Medical Investment Opportunity
$3,500,000
20,034 SF

Multi-Tenant Office/Medical Investment Opportunity

20,034 SF office/medical property with high occupancy and solar panels.

10789 Bradford Rd, Littleton, CO 80127
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Littleton Medical/Office Building For Sale
$4,750,000
30,447 SF

Littleton Medical/Office Building For Sale

30,447 SF medical/office building in Littleton, CO for sale.

7761 Shaffer Pkwy, Littleton, CO 80127
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Littleton Medical Office Building For Sale
$4,500,000
17,792 SF

Littleton Medical Office Building For Sale

17,792 SF medical office building in Southpark, Littleton.

8381 Southpark Ln, Littleton, CO 80120
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Ken Caryl Executive Plaza
$5,250,000
26,968 SF

Ken Caryl Executive Plaza

26,968 RSF medical office building with high occupancy.

10268 W Centennial Road, Littleton, CO 80127
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Littleton Commercial Property for Sale
$4,358,000
8,044 SF

Littleton Commercial Property for Sale

Commercial property in Littleton, Colorado, suitable for various uses.

7911 Shaffer Pkwy, Littleton, CO 80127
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Office
$1,800,000
5,000 SF

Office

Medical Office Space · 5,000 SF

9102 W Ken Caryl Ave, Littleton, CO 80128
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Grand Junction Commercial Land Opportunity
$17,728 /Mo

Grand Junction Commercial Land Opportunity

1.36 acre commercial land for lease in Grand Junction.

Sanford Drive, Grand Junction, CO 81505
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Grand Junction Commercial Land Lease
$9,656 /Mo

Grand Junction Commercial Land Lease

0.74 acre commercial land for lease in Grand Junction.

Highway 6&50, Grand Junction, CO 81505
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El Paso Commercial Land Lease
$3,600 /Mo

El Paso Commercial Land Lease

Commercial land for lease in a strategic El Paso location.

5538 E Paisano Drive, El Paso, TX 79905
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Highway 72 Corner Lot
$6,500 /Mo
1,875 SF

Highway 72 Corner Lot

1.6 acre commercial lot for rent on Highway 72.

30472 Highway 72, Madison, AL 35756
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Littleton, CO Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Littleton, CO with 11 listings featured on our commercial real estate exchange. The current inventory includes 1,786,613,400 square feet of properties with an estimated lease value of $100 SF/Yr.

Estimated lease rates for Medical Office Space in Littleton, CO begin at $16 SF/Yr, with an average of $25 SF/Yr and extend to $30 SF/Yr.
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