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    Littleton, CO Medical Office Space for Lease

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    Denver, CO Colorado Springs, CO Boulder, CO
    11 results
    Ken Caryl Business Center Suites
    $19 SF/Yr
    5,500 SF

    Ken Caryl Business Center Suites

    7610 - 7640 S Alkire Pl, Littleton, CO 80127

    Office, medical, flex, and retail spaces available for lease.

    • Affordable lease rates at $19.50/SF Modified Gross.
    • Build‑to‑suit opportunity for Buildings 7630 & 7640.
    • Well‑located off C‑470 and W Ken Caryl Ave in Littleton, providing quick access to C‑470.
    • Suites available for professional office, medical office, high‑end flex, and quasi‑retail use.
    • Located in a dense retail corridor with numerous restaurants, banking, hotels, and shopping options.
    Updated: Jan 27
    View details
    Littleton Medical Arts Building For Lease
    $28 SF/Yr

    Littleton Medical Arts Building For Lease

    8340 Sangre de Cristo Rd., Littleton, CO 80127

    Littleton Medical Arts Building For Lease

    • Recently updated by new owner in 2022
    • Motivated Landlord
    • Tenant improvement (TI) dollars available
    • Opportunity for building signage
    Updated: May 19, 2025
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    Medical Office Sublease Opportunity
    Contact for pricing
    7,430 SF

    Medical Office Sublease Opportunity

    Freestanding medical office building with ample parking available for sublease.

    13351 W Bowles Ave, Littleton, CO
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    Littleton Office Sublease Opportunity
    $18 SF/Yr
    1,500 SF

    Littleton Office Sublease Opportunity

    Office sublease with exam rooms, provider offices, and shared spaces.

    7261 S Broadway, Littleton, CO
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    Medical Office Space Available
    Contact for pricing

    Medical Office Space Available

    Suburban medical office space with ample parking and strong demographics.

    8340 Sangre De Cristo Rd, Littleton, CO 80127
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    Medical Office Building For Lease
    Contact for pricing
    17,012 SF

    Medical Office Building For Lease

    Proposed medical office building with spaces available for lease.

    7560 S Pierce St, Littleton, CO
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    Modernized Medical and Professional Campus
    Contact for pricing
    4,259 SF

    Modernized Medical and Professional Campus

    Healthcare-ready property in Denver's southwest corridor near the Tech Center.

    10184 W Belleview Ave, Littleton, CO 80127
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    Retail Space for Neighborhood Uses
    Contact for pricing

    Retail Space for Neighborhood Uses

    Retail spaces suitable for breweries, barbershops, fitness, and medical.

    8250 W Coal Mine Ave, Littleton, CO 80123
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    Littleton Office Space For Rent
    $16 SF/Yr
    3,866 SF

    Littleton Office Space For Rent

    Office space for lease near hospitals and shopping center.

    801 W Mineral Ave, Littleton, CO
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    Medical Office Space Available
    $26 SF/Yr
    2,045 SF

    Medical Office Space Available

    Medical office space near AdventHealth Littleton, 2045 square feet.

    414 E Mineral Ave, Littleton, CO
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    Redevelopment Opportunity in Littleton, Colorado
    Contact for pricing
    15,000 SF

    Redevelopment Opportunity in Littleton, Colorado

    Land and medical office space available for lease or purchase.

    Ken Caryl Avenue & Pierce Street, Littleton, CO 80128
    View details
    Based on your search, we've compiled 26 Potential Opportunities for your consideration. Besides 11 Active listings in Littleton, CO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Highlands Ranch Medical/Office Space
    Contact for pricing

    Highlands Ranch Medical/Office Space

    Medical and office spaces available for lease in Highlands Ranch.

    9135 South Ridgeline Boulevard, Highlands Ranch, CO 80129
    View details
    Hampden CenterEnglewood, CO 80110
    $19 SF/Yr

    Hampden CenterEnglewood, CO 80110

    565 - 28,791 SF of Space Available

    750 W Hampden Ave Englewood, CO 80110, Englewood, CO 80110
    View details
    Highlands Ranch Medical Office Space
    Contact for pricing
    7,976 SF

    Highlands Ranch Medical Office Space

    7,976 SF medical office space available for lease.

    200 W County Line Rd, Highlands Ranch, CO
    View details
    Englewood Retail Space Available
    Contact for pricing
    2,600 SF

    Englewood Retail Space Available

    2,600 SF retail space with high visibility.

    4989 S Broadway, Englewood, CO 80113
    View details

    Explore Similar Spaces for Sale in Littleton, CO

    Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

    Turnkey Medical Office Building
    $3,750,000
    14,846 SF

    Turnkey Medical Office Building

    Modernized 14,846 SF medical office in Littleton for sale.

    20 W Dry Creek Circle, Littleton, CO 80120
    View details
    Multi-Tenant Office/Medical Investment Opportunity
    $3,500,000
    20,034 SF

    Multi-Tenant Office/Medical Investment Opportunity

    20,034 SF office/medical property with high occupancy and solar panels.

    10789 Bradford Rd, Littleton, CO 80127
    View details
    Littleton Medical/Office Building For Sale
    $4,750,000
    30,447 SF

    Littleton Medical/Office Building For Sale

    30,447 SF medical/office building in Littleton, CO for sale.

    7761 Shaffer Pkwy, Littleton, CO 80127
    View details
    Littleton Medical Office Building For Sale
    $4,500,000
    17,792 SF

    Littleton Medical Office Building For Sale

    17,792 SF medical office building in Southpark, Littleton.

    8381 Southpark Ln, Littleton, CO 80120
    View details
    Ken Caryl Executive Plaza
    $5,250,000
    26,968 SF

    Ken Caryl Executive Plaza

    26,968 RSF medical office building with high occupancy.

    10268 W Centennial Road, Littleton, CO 80127
    View details
    Littleton Commercial Property for Sale
    $4,358,000
    8,044 SF

    Littleton Commercial Property for Sale

    Commercial property in Littleton, Colorado, suitable for various uses.

    7911 Shaffer Pkwy, Littleton, CO 80127
    View details
    Office
    $1,800,000
    5,000 SF

    Office

    Medical Office Space · 5,000 SF

    9102 W Ken Caryl Ave, Littleton, CO 80128
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Grand Junction Commercial Land Opportunity
    $17,728 /Mo

    Grand Junction Commercial Land Opportunity

    1.36 acre commercial land for lease in Grand Junction.

    Sanford Drive, Grand Junction, CO 81505
    View details
    Grand Junction Commercial Land Lease
    $9,656 /Mo

    Grand Junction Commercial Land Lease

    0.74 acre commercial land for lease in Grand Junction.

    Highway 6&50, Grand Junction, CO 81505
    View details
    El Paso Commercial Land Lease
    $3,600 /Mo

    El Paso Commercial Land Lease

    Commercial land for lease in a strategic El Paso location.

    5538 E Paisano Drive, El Paso, TX 79905
    View details
    Highway 72 Corner Lot
    $6,500 /Mo
    1,875 SF

    Highway 72 Corner Lot

    1.6 acre commercial lot for rent on Highway 72.

    30472 Highway 72, Madison, AL 35756
    View details

    Littleton, CO Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Littleton, CO with 11 listings featured on our commercial real estate exchange. The current inventory includes 1,786,613,400 square feet of properties with an estimated lease value of $100 SF/Yr.

    Estimated lease rates for Medical Office Space in Littleton, CO begin at $16 SF/Yr, with an average of $25 SF/Yr and extend to $30 SF/Yr.
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    Browse Medical Office Space for Lease Near Littleton, CO

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    Most Searched ZIP Codes in Littleton, CO

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    • 80123
    • 80128

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