Littleton, CO Commercial real estate for sale

Updated: Oct 5

Medical Office Building with Multiple Suites

5401 S Prince Street, Littleton, CO 80120

$1,590,000

5,778 sqft 0.33 AC lot

5,778 SF professional and medical office building on 0.33 acres
12 suites ranging from approximately 138 to 848 SF
Approximately 709 SF available
84% leased on short‑term, full‑service gross leases
DMU 3 zoning within the Littleton Downtown Development Authority

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Updated: Oct 23

Live-Work Space with Private Offices

5721 S Spotswood St, Littleton, CO 80120

$585,000

1,120 sqft

Four private offices, a conference room, and a kitchen
1,120 SF freestanding property built in 1928
Basement includes a nonconforming bedroom or office
Five dedicated parking spaces, plus street parking
Private backyard

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Industrial Auto Shop with Secured Yard

8537 S Reed Street, Littleton, CO 80128

$1,600,000

4,608 sqft 0.36 AC lot

4,608-square-foot shop on a fenced corner lot with three drive-in bays, vehicle lift, office, restroom, and secured yard.

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Turnkey Medical Office Building

20 W Dry Creek Circle, Littleton, CO 80120

$3,750,000

14,846 sqft 2.00 AC lot

Modernized medical office building in Littleton's healthcare corridor.

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Upgraded Flex Condominium with Mezzanine

9337 Commerce Center #C4, Littleton, CO 80129

$789,000

2,900 sqft

Climate-controlled mezzanine, expanded electrical service, and automotive equipment support varied workspace needs.

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Modernized Medical Office Building

20 W Dry Creek, Littleton, CO 80120

$3,750,000

14,846 sqft 2.00 AC lot

Vacant medical office property with direct-entry suites and on-site surface parking.

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Office Condo with Private Reception

B-13976 W Bowles Ave, Littleton, CO 80127

$357,740

1,276 sqft

Thoughtfully laid-out suite with private reception, four offices, private restroom, kitchenette, and Quantum Fiber connectivity.

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Heavy Industrial Flex Warehouse

9861 Titan Park Circle, Littleton, CO 80125

$1,650,000

3,750 sqft

2019-built flex warehouse zoned heavy industrial with drive-in doors, ADA restrooms, and outdoor storage.

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Restaurant Space with Bar

8100 W Crestline Avenue, Littleton, CO 80123

$225,000

2,535 sqft

A commercial kitchen, walk-in cooler, booth seating, and bar area support the existing restaurant layout.

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Multi-Building Industrial Portfolio

5239 5259 & 5265 S Rio Grande St., Littleton, CO 80120

$14,000,000

78,489 sqft 5.95 AC lot

Several industrial buildings occupy a contiguous site with current tenants in place.

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Littleton Medical/Office Building For Sale

7761 Shaffer Pkwy, Littleton, CO 80127

$4,750,000

30,447 sqft

30,447 SF medical/office building in Littleton, CO for sale.

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Open Flex Condominium

11786 Shaffer Place S202, Littleton, CO 80127

$399,000

1,098 sqft

Versatile commercial condominium with shared clubhouse amenities and on-site vehicle service facilities.

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Two-Story Office Building

10390 Bradford Road, Littleton, CO 80127

$2,500,000

12,462 sqft

Shared conference and break areas complement an elevator-served, ADA-compliant layout.

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Historic Mixed-Use Main Street Building

2340 W Main St, Littleton, CO 80120

$750,000

1,742 sqft

Two-story downtown property combines leased ground-floor retail with adaptable upper-level space for residential or office conversion.

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Retail Building at Signalized Intersection

9106 West Bowles Avenue, Littleton, CO 80123

Contact for pricing

5,500 sqft 1.37 AC lot

Established retail space with prominent Bowles Avenue exposure and a location across from major retail anchors.

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Classic Littleton Office Building

709 W Littleton Boulevard, Littleton, CO 80120

$1,575,000

10,530 sqft

Three-level office building in revitalizing Littleton Boulevard area.

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Multi-Tenant Office Building

7800 S Elati Street, Littleton, CO 80120

Contact for pricing

26,835 sqft 1.22 AC lot

Three-story office property with four suites ready for lease and a layout centered on smaller offices.

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Pad Site Commercial Land

5869 S Alkire St, Littleton, CO 80127

$1,200,000

1.00 AC lot

One-acre pad site available for sale, ground lease, or build-to-suit development planning.

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Live-Work Space with Rooftop Deck

5439 South Prince Street, Littleton, CO 80120

Contact for pricing

4,275 sqft

Vacant mixed-use property combines flexible office space with a refined residential loft and multiple outdoor areas.

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Ground-Level Office Condo Suite

7621 Shaffer Pkwy, Littleton, CO 80127

Contact for pricing

1,993 sqft

Ground-level office condo features two HVAC units, ADA restrooms, and a kitchenette with private main entrance.

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Historic Mixed-Use Live-Work Property

2606 West Alamo Avenue, Littleton, CO 80120

$1,375,000

4,942 sqft

Two downtown buildings combine retail, office, and flexible live-work potential.

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Fully Fixtured Dry Cleaners Space

Littleton, CO 80126

Contact for pricing

3,390 sqft

Equipped dry cleaning space available for lease.

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Specialty Property with Mountain Views

7833 S Estes Ct, Littleton, CO 80128

$69,000

12,197 sqft

Specialty property with mountain views in Jefferson County, Colorado.

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Fully Occupied Three-Tenant Strip Mall

Littleton, CO 80124

$6,888,000

Established retail center with corporate leases, expense reimbursements, and an additional wireless communications facility.

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Littleton, CO Commercial Real Estate Market Trends and Statistics

Explore 75 commercial real estate for sale in Littleton, CO, showcased through 75 active listings on our real estate platform. These investment opportunities span a total of 929,392 square feet of properties for sale, with an estimated market value of $64,129,540.

Sale prices for business properties in Littleton, CO start at $69,000, averaging $2,068,694, and reaching up to $14,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Littleton, CO CRE market trends — vacancy, lease rates and price per SF, updated monthly

Neighborhood	Average Price
80129	$496.3K
80128	$834.5K
80125	$1.1M
80127	$1.3M
80123	$1.7M

Neighborhood

Average Price

80129

$496.3K

80128

$834.5K

80125

$1.1M

80127

$1.3M

80123

$1.7M