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Littleton, CO Office Spaces for Lease

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Renovated Medical Office Suite
Updated: May 1
Renovated Medical Office Suite

8089 S Lincoln St, Littleton, CO 80122

$2,261/Mo
1,085‑square‑foot Suite 201
Renovated medical office building constructed in 1984
Elevator service and 24‑hour building access
Monument signage opportunities and on‑site parking
Near Littleton Adventist Hospital and UCHealth Highlands Ranch Hospital
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Corner Office Suite with Restrooms
Updated: Jun 23
Corner Office Suite with Restrooms

1350 - 1360 West Littleton Boulevard, Littleton, CO 80120

$15 SF/Yr
1,868 sqft
Unit D is a 1,868 SF corner unit in a shopping center
Includes 2 offices and 2 restrooms
NNN shopping center expenses listed as $11.92/SF
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Flexible First-Generation Flex Space
Flexible First-Generation Flex Space

5391 S Alkire St, Littleton, CO 80127

$12 SF/Yr
2 sqft

Adaptable commercial space supports office, showroom, light industrial, and research and development operations.

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Littleton Office Suites For Lease
Littleton Office Suites For Lease

10390 Bradford Rd, Littleton, CO 80127

$20 SF/Yr
1,557 sqft

Multiple office spaces available in Littleton, from 350 to 1,557 SF.

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Freestanding Office Building with Parking
Freestanding Office Building with Parking

5639 South Curtice Street, Littleton, CO 80120

$2,950/Mo
750 sqft

Freestanding 750 SF office suite with off-street dedicated parking, open layout, and private restroom with shower.

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Updated Office Unit with Kitchenette
Updated Office Unit with Kitchenette

102a-13984 W Bowles Avenue, Littleton, CO 80127

$1,800/Mo

Light-filled office suite with private restroom, storage, and gross lease structure including utilities and building services.

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Littleton Office Suites For Lease
Littleton Office Suites For Lease

10390 Bradford Road, Littleton, CO 80127

$20 SF/Yr
12,462 sqft

Multiple office spaces available in Littleton, from 350 to 1,557 SF.

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Flexible workspace at Shea Center. Contact us today to book a tour!
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Medical Office Suite Near Hospital Campus
Medical Office Suite Near Hospital Campus

6179 S Balsam Way, Littleton, CO 80123

Contact for pricing
8,690 sqft

Outpatient medical space with surface parking, directory signage, and after-hours security sweeps.

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Versatile Office Space Available
Versatile Office Space Available

5808 S Rapp St, Littleton, CO 80120

$19.50 SF/Yr
30,678 sqft

Office space for lease in a convenient Littleton location.

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Littleton Office Space for Rent
Littleton Office Space for Rent

7851 S Elati St 101, Littleton, CO 80120

$975/Mo per office

Affordable private and shared office spaces with amenities in Littleton.

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Professional Office Building with Open Layout
Professional Office Building with Open Layout

5878 S Rapp St, Littleton, CO 80120

$20 SF/Yr

Well-maintained office building off Santa Fe Dr with an open floorplan and permissive zoning for flexible use.

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Office Building For Lease
Office Building For Lease

300 Plaza Drive, Littleton, CO 80221

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9,393 sqft

Office building available for lease at 300 Plaza Drive in Littleton.

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Divisible Office Floor
Divisible Office Floor

10901 West Toller Drive, Littleton, CO 80127

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18,860 sqft 5.20 AC lot

Highly efficient full-floor office space offers 9-foot ceilings and can be divided into smaller suites.

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Updated Office Space For Rent
Updated Office Space For Rent

1510 W Canal Ct, Littleton, CO 80120

$14 SF/Yr
16,369 sqft

Modern office space with natural light and ample parking.

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Medical Office Building with Surgery Center
Medical Office Building with Surgery Center

8381 Southpark Lane, Littleton, CO 80120

Contact for pricing
17,792 sqft

A zoned BC/PL-O medical office building with multiple suites anchored by a licensed surgery center.

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Flex Office and Warehouse Suite
Flex Office and Warehouse Suite

8122 Southpark Ln, Littleton, CO 80120

Contact for pricing
27,390 sqft

Suite 100 includes five offices, a restroom, about 2,000 sf of warehouse, and two overhead doors.

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Second-Generation Medical Office Suite
Second-Generation Medical Office Suite

5920 S Estes St, Littleton, CO 80123

Contact for pricing
4,532 sqft

Move-in ready 4,532 SF second-floor medical suite with direct first-floor access from the main entrance.

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Littleton Office Space For Rent
Littleton Office Space For Rent

7851 S Elati Street #101, Littleton, CO 80120

$975/Mo per office

Affordable office spaces with shared amenities and convenient location.

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First-Generation Flex Space
First-Generation Flex Space

5391 South Alkire Street, Littleton, CO 80127

Contact for pricing
41,825 sqft

Adaptable commercial space supports office, showroom, light industrial, research, development, technology, and service-oriented operations.

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Professional Office and Medical Suites
Professional Office and Medical Suites

8 West Dry Creek Circle, Littleton, CO 80122

$22 SF/Yr

Office and medical-dental space within Highline Professional Center, with convenient access near major roadways and amenities.

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Freestanding Office Building
Freestanding Office Building

1979 W Littleton Blvd, Littleton, CO 80120

Contact for pricing
12,632 sqft

Well-maintained freestanding converted office building with updated exterior doors and windows and strong visibility off Littleton Blvd.

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Office Space with Natural Light
Office Space with Natural Light

7991 Shaffer Pkwy, Littleton, CO 80127

Contact for pricing
3,161 sqft

3,161 SF office space featuring private offices and amenities.

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Ground-Level Coworking Space
Ground-Level Coworking Space

101-7851 S Elati St, Littleton, CO 80120

$500-$975/Mo per office

Flexible shared and private offices include conference facilities, kitchen access, and weekday on-site reception.

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Littleton, CO Office Spaces Lease Rates & Market Statistics

Browse 60 Office Spaces for lease in Littleton, CO on Realmo, a commercial real estate marketplace serving the Littleton area. The current inventory totals 332,486 square feet of properties — an average of ~5,550 SF per listing.

Asking lease rates for Office Spaces in Littleton start at $12 SF/Yr, average $20.65 SF/Yr, and reach $47.20 SF/Yr at the top of the market. That's a 4x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $20.65 SF/Yr is in line with the Colorado state average.

Littleton accounts for 6% of the 1,063 office spaces currently available across Arapahoe County, where nearby markets include Denver and Greenwood Village. By space type, the market includes 42 office units, 15 medical office space listings and 9 office buildings — office units typically offer the lowest entry point, while office buildings command the highest rates.

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