Medical Premises

Littleton, CO Medical Office Space for Sale

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Medical Office Building with Multiple Suites
Updated: Oct 5
Medical Office Building with Multiple Suites

5401 S Prince Street, Littleton, CO 80120

$1,590,000
5,778 sqft 0.33 AC lot
5,778 SF professional and medical office building on 0.33 acres
12 suites ranging from approximately 138 to 848 SF
Approximately 709 SF available
84% leased on short‑term, full‑service gross leases
DMU 3 zoning within the Littleton Downtown Development Authority
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Turnkey Medical Office Building
Updated: Apr 24
Turnkey Medical Office Building

20 W Dry Creek Circle, Littleton, CO 80120

$3,750,000
14,846 sqft 2.00 AC lot
Turnkey 14,846 SF medical office building (MOB) delivered vacant for immediate owner‑user occupancy.
$1.5M in 2022 upgrades; fully modernized.
Located in Littleton’s premier healthcare corridor near C‑470, South Broadway, and Littleton Adventist Hospital.
Situated on a two‑acre site with 60 surface parking spaces.
Multiple direct‑entry suites offer superior functionality.
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Modernized Medical Office Building
Modernized Medical Office Building

20 W Dry Creek, Littleton, CO 80120

$3,750,000
14,846 sqft 2.00 AC lot

Vacant medical office property with direct-entry suites and on-site surface parking.

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Littleton Medical/Office Building For Sale
Littleton Medical/Office Building For Sale

7761 Shaffer Pkwy, Littleton, CO 80127

$4,750,000
30,447 sqft

30,447 SF medical/office building in Littleton, CO for sale.

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Office
Office

9102 W Ken Caryl Ave, Littleton, CO 80128

Contact for pricing
5,000 sqft

Medical Office Space · 5,000 SF

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Based on your search, we've compiled 64 Potential Opportunities for your consideration. Besides 5 Active listings in Littleton, CO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 55 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Office Suite with Waiting Area
Office Suite with Waiting Area

9364 TEDDY LN, Lone Tree, CO 80124

Contact for pricing
1,201 sqft

Built in 2006 with a functional layout for professional service use.

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Two-Building Office Campus
Two-Building Office Campus

3150 S Sheridan Blvd, Denver, CO 80227

$2,450,000

Two connected office buildings offer classroom/training and traditional office space with ample parking near major retail anchors.

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Medical Office Condo with Treatment Rooms
Medical Office Condo with Treatment Rooms

A5-8751 E Hampden Ave, Denver, CO 80222

$149,900

Two plumbed rooms, a private restroom, and reception area support flexible clinical or professional layouts.

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Medical Office Unit with Heavy Power
Medical Office Unit with Heavy Power

10463 Park Meadows Dr, Lone Tree, CO 80124

Contact for pricing

Class A space offers dual exterior access, a procedure room, lab area, and signage potential.

View details

Off-Market Properties in Littleton, CO

Consider similar Off-Market properties in Littleton, CO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

11 Dry Crk Cir
MEDICAL BUILDING

11 Dry Crk Cir, Littleton, CO 80120-8077

Estimated value:
$2,420,000
12,409 sqft 1.34 AC lot
View details
4260 Wadsworth Blvd
MEDICAL BUILDING

4260 Wadsworth Blvd, Littleton, CO 80123-1308

Estimated value:
$1,400,000
4,958 sqft 0.69 AC lot
View details
5590 Windermere St
MEDICAL BUILDING

5590 Windermere St, Littleton, CO 80120-1245

Estimated value:
$890,000
4,540 sqft 0.39 AC lot
View details
4535 Kipling Pkwy
MEDICAL BUILDING

4535 Kipling Pkwy, Littleton, CO 80127-1139

Estimated value:
$615,000
3,234 sqft 0.30 AC lot
View details
7325 Pierce St Ste, Unit 200
MEDICAL BUILDING

7325 Pierce St Ste, Littleton, CO 80128-4553

Unit 200
Estimated value:
$375,000
1,269 sqft
View details
7325 Pierce St Ste, Unit 102
MEDICAL BUILDING

7325 Pierce St Ste, Littleton, CO 80128-4553

Unit 102
Estimated value:
$310,000
1,976 sqft
View details
7325 Pierce St Ste, Unit 101
MEDICAL BUILDING

7325 Pierce St Ste, Littleton, CO 80128-4553

Unit 101
Estimated value:
$115,000
654 sqft
View details
1480 Canal Ct
MEDICAL BUILDING

1480 Canal Ct, Littleton, CO 80120-4529

Estimated value:
$1,540,000
4,371 sqft 1.25 AC lot
View details
8340 Sangre De Cristo Rd
MEDICAL BUILDING

8340 Sangre De Cristo Rd, Littleton, CO 80127-4248

Estimated value:
$3,260,000
19,247 sqft 2.14 AC lot
View details
991 Southpark Dr
MEDICAL BUILDING

991 Southpark Dr, Littleton, CO 80120-5688

Estimated value:
$5,715,000
17,636 sqft 1.11 AC lot
View details
5920 Estes St
MEDICAL BUILDING

5920 Estes St, Littleton, CO 80123-8618

Estimated value:
$7,145,000
22,281 sqft 0.74 AC lot
View details
7889 Lincoln Ct
MEDICAL BUILDING

7889 Lincoln Ct, Littleton, CO 80122-2651

Estimated value:
$6,960,000
18,688 sqft
View details
7720 Broadway
MEDICAL BUILDING

7720 Broadway, Littleton, CO 80122-2632

Estimated value: by Request
62,720 sqft 0.01 AC lot
View details
7750 Broadway
MEDICAL BUILDING

7750 Broadway, Littleton, CO 80122-2623

Estimated value:
$11,430,000
30,324 sqft 0.01 AC lot
View details
9859 Coal Mine Ave
MEDICAL BUILDING

9859 Coal Mine Ave, Littleton, CO 80123-8003

Estimated value:
$365,000
3,856 sqft 1.54 AC lot
View details
7325 Pierce St Ste, Unit 100
MEDICAL BUILDING

7325 Pierce St Ste, Littleton, CO 80128-4553

Unit 100
Estimated value:
$505,000
1,106 sqft
View details
20 Dry Crk Cir
MEDICAL BUILDING

20 Dry Crk Cir, Littleton, CO 80120-4413

Estimated value:
$2,185,000
14,846 sqft 1.37 AC lot
View details
7325 Pierce St Ste, Unit 203
MEDICAL BUILDING

7325 Pierce St Ste, Littleton, CO 80128-4553

Unit 203
Estimated value:
$325,000
1,570 sqft
View details
7335 Pierce St
MEDICAL BUILDING

7335 Pierce St, Littleton, CO 80128-4571

Estimated value:
$2,385,000
10,684 sqft 1.46 AC lot
View details

Littleton, CO Medical Office Space Market Trends and Statistics

Explore 60 medical office space for sale in Littleton, CO, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 70,917 square feet of properties for sale, with an estimated market value of $13,840,000.

Sale prices for medical spaces in Littleton, CO start at $1,590,000, averaging $3,460,000, and reaching up to $4,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 48
Office buildings 20
Medical Office Space 19
Coworking space 5

Demographics Overview

Population 341K
Population Growth (5Y) +0.2%
Median Household Income $131,357
College Educated 54.2%

High-Yield Neighborhoods for Investment

Identify Littleton submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
80120 $3.8M
80127 $4.8M

Taxes & Financing

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Arapahoe County

New Delisted

Total CRE Inventory on Market (SF)

Property Size Breakdown

The majority of commercial real estate listings in Littleton fall within the 100,000+ square foot range.

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