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San Mateo, CA Office Spaces for Sale

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New Medical/Dental Condo For Sale
Updated: Jun 19, 2025
New Medical/Dental Condo For Sale

420 Peninsula Avenue #3, San Mateo, CA 94401

$1,499,000
4,000 sqft
Prime location on the San Mateo/Burlingame border in a high‑traffic area.
Turnkey medical/dental condo ready for immediate occupancy.
Three fully plumbed operatories ready for equipment installation.
Newly constructed in 2019 with high‑quality materials and finishes.
ADA‑compliant access and wheelchair lift.
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This listing looks promising.

Here's a quick look at some key insights for

420 Peninsula Avenue #3, SAN MATEO, CA 94401

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Corner Flex Office/Warehouse
Updated: Jun 5
Corner Flex Office/Warehouse

101 E 25th Ave, San Mateo, CA 94403

$2,800,000
3,850 sqft 0.26 AC lot
11,500 SF lot with a total of 3,850 SF renovated office and warehouse/storage space
Includes detached unit with restroom, shower, and employee lockers
Approximately 23 parking spaces with security gates
Corner parcel located on 25th and Palm Ave
Building signage available
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Versatile Building Near Caltrain
Versatile Building Near Caltrain

422-426 Peninsula Ave, San Mateo, CA 94401

$1,999,999

Adaptable building suitable for office, school, medical, or residential use.

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San Mateo Office Space Available
San Mateo Office Space Available

65-71 E 3rd Ave, San Mateo, CA

$9,900,000
5,051 sqft 0.13 AC lot

Second floor office space with elevator, conference room, and skylights.

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For-Sale Office Building
For-Sale Office Building

216 N San Mateo Drive, San Mateo, CA 94401

$2,400,000

Office building available for sale at 216 N San Mateo Drive, suited for owner-occupiers or office users.

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Medical/Dental Condo Suite
Medical/Dental Condo Suite

420 Peninsula Avenue 2, San Mateo, CA 94401

$3,000,000

Newly built medical/dental condo includes a waiting room, front desk area, and three operatories with ADA restroom and lift access.

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San Mateo Office Building Investment
San Mateo Office Building Investment

630 N San Mateo Dr, San Mateo, CA

$12,750,000
17,398 sqft 0.60 AC lot

Fully leased San Mateo office building with long-term tenant.

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San Mateo Office Building
San Mateo Office Building

1 Baywood Ave, San Mateo, CA 94402

Contact for pricing
10,960 sqft

Office building with 10,960 square feet of space.

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San Mateo Mixed-Use Investment
San Mateo Mixed-Use Investment

22 - 26 25th Avenue, San Mateo, CA 94403

$1,995,000
2,870 sqft

Fully leased mixed-use building in high-traffic San Mateo location.

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Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 9 Active listings in San Mateo, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 63 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Warehouse with Office
Warehouse with Office

330 Hatch Drive, Foster City, CA 94404

$7,850,000
17,875 sqft

Warehouse with grade-level loading and integrated office space, supported by 19’ clear height and multiple power disconnects.

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Move-In Ready Office Space
Move-In Ready Office Space

851 Burlway Rd, Burlingame, CA

Contact for pricing
2,858 sqft 1.87 AC lot

Office suites available near SFO with Bay and City views.

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Two-Story Office and Warehouse Campus
Two-Story Office and Warehouse Campus

831-839 Mitten Rd, Burlingame, CA 94010

Contact for pricing
540 sqft

Two-story campus combines office space with a standalone warehouse, plus EV charging and abundant natural light.

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Medical Building with Development Potential
Medical Building with Development Potential

1261 E Hillsdale Blvd, Foster City, CA

$6,950,000
12,760 sqft 0.99 AC lot

Single-story medical building on a prime one-acre lot.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Corner Lot in Burlingame
Prime Corner Lot in Burlingame

Hillsborough, CA 94010

$11,500,000
11,000 sqft 0.65 AC lot

Iconic building site with development potential near downtown.

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El Sobrante Land Opportunity
El Sobrante Land Opportunity

425 Appian Way, El Sobrante, CA 94803

$1,350,000
10,000 sqft

Commercial land available off San Pablo Dam Road.

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Commercial Parcel in Livermore Hub
Commercial Parcel in Livermore Hub

2901 Las Positas Road, Livermore, CA 94551

$1,900,000
0.93 AC lot

Prime commercial land in established retail and service hub.

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Corner Lot Near Downtown
Corner Lot Near Downtown

310 310 Central Ave, Pittsburg, CA 94565

$1,650,000

Commercial land near downtown and E-Bart Station.

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Off-Market Properties in San Mateo, CA

Consider similar Off-Market properties in San Mateo, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

2 3rd Ave
OFFICE BUILDING (MULTI-STORY)

2 3rd Ave, San Mateo, CA 94401-4285

$8,035,000
Estimated value
24,780 sqft 0.20 AC lot
View details
2015 Pioneer Ct
OFFICE BUILDING (MULTI-STORY)

2015 Pioneer Ct, San Mateo, CA 94403-1781

$5,650,000
Estimated value
0.44 AC lot
View details
1 Baywood Ave
PROFESSIONAL BUILDING

1 Baywood Ave, San Mateo, CA 94402-1523

$790,000
Estimated value
0.49 AC lot
View details
1840 Gtwy Dr
OFFICE BUILDING (MULTI-STORY)

1840 Gtwy Dr, San Mateo, CA 94404-4027

$12,160,000
Estimated value
69,000 sqft 2.54 AC lot
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215 San Mateo Dr
PROFESSIONAL BUILDING

215 San Mateo Dr, San Mateo, CA 94401-2622

Value Estimation by Request
6,250 sqft 0.33 AC lot
View details
330 Claremont St
OFFICE BUILDING (MULTI-STORY)

330 Claremont St, San Mateo, CA 94401-3314

$22,730,000
Estimated value
65,625 sqft 0.51 AC lot
View details
1700 El Camino Real
OFFICE BUILDING (MULTI-STORY)

1700 El Camino Real, San Mateo, CA 94402-3047

$13,110,000
Estimated value
77,715 sqft 3.10 AC lot
View details
675 Mariners Is Blvd Ste, Unit 109
PROFESSIONAL BUILDING

675 Mariners Is Blvd Ste, San Mateo, CA 94404-1040

Unit 109
Value Estimation by Request
0.04 AC lot
View details
2070 Pioneer Ct
OFFICE BUILDING (MULTI-STORY)

2070 Pioneer Ct, San Mateo, CA 94403-1720

$1,085,000
Estimated value
0.30 AC lot
View details
1919 Ofarrell St
PROFESSIONAL BUILDING

1919 Ofarrell St, San Mateo, CA 94403-1384

$2,850,000
Estimated value
3,798 sqft 0.69 AC lot
View details
477 9th Ave
OFFICE BUILDING (MULTI-STORY)

477 9th Ave, San Mateo, CA 94402-1888

Value Estimation by Request
1.61 AC lot
View details
2322 El Camino Real
OFFICE BUILDING (MULTI-STORY)

2322 El Camino Real, San Mateo, CA 94403-2214

$695,000
Estimated value
3,666 sqft 0.17 AC lot
View details
3155 Clearview Way
OFFICE BUILDING (MULTI-STORY)

3155 Clearview Way, San Mateo, CA 94402-3711

$20,725,000
Estimated value
65,977 sqft 4.69 AC lot
View details
3000 Clearview Way
OFFICE BUILDING (MULTI-STORY)

3000 Clearview Way, San Mateo, CA 94402-3710

$34,755,000
Estimated value
110,876 sqft 17.16 AC lot
View details
2121 El Camino Real
OFFICE BUILDING (MULTI-STORY)

2121 El Camino Real, San Mateo, CA 94403-1855

Value Estimation by Request
208,550 sqft 3.15 AC lot
View details

San Mateo, CA Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in San Mateo, CA, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 33,169 square feet of properties for sale, with an estimated market value of $28,944,000.

Sale prices for office spaces in San Mateo, CA start at $1,499,000, averaging $5,788,800, and reaching up to $12,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 58
Office buildings 19
Medical Office Space 6
Creative space 3
Coworking space 2

Demographics Overview

Population 141K
Population Growth (5Y) -1.2%
Median Household Income $165,615
College Educated 74.2%

High-Yield Neighborhoods for Investment

Identify San Mateo submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
94401 $2.2M
94403 $2.7M
94402 $3.9M

Taxes & Financing

Tax Rate (average for all types) 1.30%
Property Tax per SF $7.54 per SF
Tax Rate vs County Average 0.17 pp above county avg
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in San Mateo County

New Delisted

Total CRE Inventory on Market (SF)

Average Property Price per SF

For-sale pricing trends across core commercial property types in San Mateo County

Retail

Residential Income

Property Size Breakdown

The majority of commercial real estate listings in San Mateo fall within the 100,000+ square foot range.

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