Galveston County, TX Office Spaces for Rent & Lease

Flexible Offices and Coworking at South Shore. Contact us today to book a tour!

2600 South Shores Blvd, Unit 300, League City, TX 77573

16 available spaces from 11 to 1,992 sqft

$129-$25,211/Mo per office

(972) 764-8885

Flexible workspace in South Shore. Book a tour & get info

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Updated: May 27

Office Condo with Reception Area

1501 North Amburn Road, Texas City, TX 77591

$216 SF/Yr

2,956 sqft

2,956 SF two‑level office condo in a well‑maintained professional complex in Texas City, TX
Downstairs layout includes reception/waiting area, multifunctional workstation area, restroom, break area, two offices, and storage room
Upstairs offers two private rooms, full bathroom with shower, spacious common area, and large storage closet
Located just off FM 1764, across from College of the Mainland
Easy access to Emmett F. Lowry Expressway, with close proximity to I‑45 and Highway 146

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Updated: Oct 30

Flex Space with Finished Offices

404 Newport Blvd, League City, TX 77573

Contact for pricing

2,400 sqft

Approximately 2,400 SF of finished office space
Office layout includes reception, two private offices, shared workspace, and a conference and break area
Updated with laminate flooring, commercial carpeting, LED flat‑panel lighting, and upgraded cabinetry
Access control system and security cameras included; monthly monitoring and service fees apply
At 404 Newport Blvd, just off FM 518 and approximately ¼ mile from I‑45

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Office Unit with Dual Entrances

880 Lawrence Road, League City, TX 77573

Triple net (NNN)

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4–6 people 1 space 1,000 sqft 1-story

A ground-level office suite has two separate entry points, insulated concrete walls, and hurricane-rated windows.

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Medical Office with Exam Rooms

2095 West Main Street, League City, TX 77573

Triple net (NNN)

$17 SF/Yr

Patient-care space includes imaging, laboratory, examination, and administrative areas.

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One-Story Medical Office Building

7236 Medical Center Drive, Texas City, TX 77591

Contact for pricing

7,860 sqft 1-story 0.84 acres

Highway access

Vacant one-story medical facility near a hospital campus, offering flexible single-tenant or two-suite use with ample parking.

24 parking spaces

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Office Unit with Pylon Signage

107 S Friendswood Dr, Friendswood, TX 77546

Full service

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2–4 people 1 space 610 sqft

Utilities are included, with tenant-paid internet and no NNN charges.

Pylon sign

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New Medical Professional Center

1070 FM 646 Road East, League City, TX 77573

$24 SF/Yr

Highway access

Newly constructed medical and professional center offering space suited for an imaging center and physical therapy clinic.

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First-Floor Office Space with Two Entrances

820 Lawrence Road, League City, TX 77573

Triple net (NNN)

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3–6 people 1 space 900 sqft 1-story

Single-story office suite features two entry doors, 10-foot ceilings, concrete walls, and hurricane glass windows.

High-speed internet

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Professional/Medical Office Space Available

1455 FM 646 West, League City, TX 77573

$20 SF/Yr

Built 2015

Two-story office building near Gulf Freeway and UTMB Health.

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Office/Retail Space on High-Traffic Road

549 Egret Bay Boulevard, League City, TX 77573

$24 SF/Yr

1 space

Versatile space suitable for office or retail use.

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Medical Office Space For Rent

3023 Marina Bay Dr -Ste 205, League City, TX 77573

$15 SF/Yr

Professional Center at South Shore Harbour, League City, TX

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Medical Office Space Available

6807 Emmett F Lowry Expy, Texas City, TX

Contact for pricing

3,511 sqft 1.92 acres

Medical office space for lease near HCA Houston Healthcare.

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High-Visibility Retail and Flex Space

2403 Gulf Freeway S, League City, TX

Triple net (NNN)

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10,000 sqft

Newly built 10,000 SF retail/flex space with freeway visibility.

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Multi-Level Elevator-Served Medical Building

18009 Blackhawk Boulevard, Friendswood, TX 77546

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Road access

Proposed multi-level medical and professional building with elevator service and multi-level covered parking garage.

Multi-level covered parking garage Potential exclusive signage rights Elevator

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Prime Medical and Retail Space

1320 West League City Parkway, League City, TX 77573

$30 SF/Yr

Medical and retail spaces available in League City, Texas.

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Value-Add Office Building Opportunity

3027 Marina Bay Dr, League City, TX 77573

Gross

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4–7 people 7 spaces 1,059 sqft

Class B office building with value-add potential in Clear Lake.

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Two-Story Office Building with Bank Anchor

6501 Stewart Rd, Galveston, TX 77551

Modified gross

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22–36 people 1 space 5,500 sqft 2-story

Two-story office building anchored by Texas First Bank, offering access to Downtown Galveston, the Port, and heavily traveled roadways.

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Three-Story Atrium Office Building

3027 Marina Bay Dr, League City, TX 77573

Gross

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4–8 people 1 space 1,225 sqft 3-story

Three-story atrium office building with upscale interior finishes, ample parking, and monument signage opportunity.

Atrium Upscale interior finishes Ample parking Monument signage opportunity

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Two-Story Office Building

104 Twin Oaks Boulevard, Kemah, TX 77565

Modified gross

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20–33 people 1 space 5,000 sqft 2-story

Well-maintained two-story office center with first-floor build-outs and a second-floor shell suite ready for customization.

Monument signage

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Atrium Office Building

3027 Marina Bay Dr, League City, TX 77573

Gross

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19–33 people 1 space 4,997 sqft 3-story

Road access

Three-story atrium office building offering upscale interior finishes and ample parking.

Monument signage

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21 active listings match your search: Office for lease in Galveston County, TX. Based on your search, we've also compiled 18 Potential Opportunities for your consideration: 18 properties for sale.

Similar Spaces for Sale in Galveston County, TX

Consider Similar Space for Sale. We found 18 Spaces matching your search parameters.

Remodeled Twin Flex Office-Warehouse Spaces

404- 406 Newport Boulevard, League City, TX 77573

$990,000

33,773 sqft 0.77 AC lot

Two modern flex suites combine private offices, warehouse areas, and parking for service-oriented business operations.

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Mixed-Use Live-Work Opportunity

4609 Broadway Street 3, Galveston, TX 77551

$500,000

2,500 sqft

Mixed-use property combining updated residential space with ground-floor commercial area in shell condition.

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Creative Space with Chapel Architecture

4720 Avenue O 1/2, Galveston, TX 77551

$1,100,000

7,664 sqft

Two adaptable structures surround a central courtyard with workshop and studio-style interiors.

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