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    Guadalupe County, TX Office Properties & Spaces for Lease

    32 results
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    Prime Commercial Space in Seguin
    $2,500 / Mo
    1,200 SF

    Prime Commercial Space in Seguin

    211 E Court St, Seguin, TX 78155

    Updated 1,200 SF commercial space in downtown Seguin.

    • Prime downtown Seguin location, just off the square.
    • 1,200 sq ft commercial space with immediate street visibility.
    • Turnkey‑ready with high‑appeal finishes, new flooring, and fresh paint.
    • Suitable for cafe, boutique, studio, office, or retail.
    • Kitchen equipment and furniture are negotiable.
    Updated: Mar 20
    View details
    Adaptable Commercial Building in Seguin
    $30 SF/Yr
    13,026 SF

    Adaptable Commercial Building in Seguin

    936 S Highway 123 Byp, Seguin, TX 78155

    Well-maintained commercial building in high-traffic area, ideal for business.

    • High‑visibility, high‑traffic location ideal for attracting clients/patients.
    • Adaptable space with multiple private offices/exam rooms.
    • Up to 4,000 sq. ft. available, suitable for a growing business.
    • Well‑maintained Class B commercial building.
    • Layout designed for seamless daily operations.
    Updated: Mar 21
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    Seguin Commercial Shop on Acres
    $3,000 / Mo
    1,856 SF

    Seguin Commercial Shop on Acres

    Spacious shop on 5 acres, ideal for various businesses.

    1758 Ilka Switch, Seguin, TX 78155
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    Office and Warehouse Building Available
    $4,500 / Mo
    16,555 SF

    Office and Warehouse Building Available

    16,555 sq ft office/warehouse on 2.61 acres.

    1012 Schriewer, Seguin, TX 78155
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    Renovated Commercial Space Available
    $1,595 / Mo
    1,565 SF

    Renovated Commercial Space Available

    Renovated commercial space with original hardwood floors, available April 2026.

    1427 N Austin St, Seguin, TX 78155
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    Historic Downtown Seguin Commercial Building
    $4,888 / Mo
    4,250 SF

    Historic Downtown Seguin Commercial Building

    Two-story commercial building in historic downtown Seguin available for rent.

    109 N River St, Seguin, TX 78155
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    Move-in Ready Commercial Space
    $1,500 / Mo
    5,400 SF

    Move-in Ready Commercial Space

    Commercial space near Guadalupe Regional Medical Center in Seguin, TX.

    412 N King St, Seguin, TX 78155
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    Highway Frontage Commercial Space
    $1,250 / Mo
    6,750 SF

    Highway Frontage Commercial Space

    Commercial space for lease with high traffic and visibility.

    2331 N State Highway 46, Seguin, TX 78155
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    Seguin Office Space For Rent
    $3,800 / Mo
    2,442 SF

    Seguin Office Space For Rent

    Office space available on IH 10 in Seguin, TX.

    3040 W Interstate 10 Expy, Seguin, TX 78155
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    Versatile Flex Space in Seguin
    $4,500 / Mo

    Versatile Flex Space in Seguin

    16,555 sq ft flex building on 2.61 acres.

    1012 Schriewer, Seguin, TX 78155
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    Adaptable Commercial Space For Rent
    $30 SF/Yr

    Adaptable Commercial Space For Rent

    Well-maintained Class B commercial building in high-traffic area.

    936 S Highway 123 Byp, Seguin, TX 78155
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    Industrial Warehouse with Office Space
    $2,750 / Mo

    Industrial Warehouse with Office Space

    Warehouse with offices, kitchen, and bathroom near Hwy 90.

    3701 Auxiliary Airport Rd, Seguin, TX 78155
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    Medical Office Space For Rent
    $1,500 / Mo

    Medical Office Space For Rent

    Move-in ready medical office space near Guadalupe Regional Medical Center.

    412 N King St, Seguin, TX 78155
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    Versatile Commercial Leasing Opportunity
    $0.95 SF/Yr

    Versatile Commercial Leasing Opportunity

    Premier commercial complex with flexible build-out options and ample yard space.

    7049 Fm 1044, Marion, TX 78124
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    Seguin Office Space For Rent
    $6 SF/Yr

    Seguin Office Space For Rent

    Opportunity to build out space to tenant desires.

    1115 N Bowie St, Seguin, TX 78155
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    Office Space Available For Rent
    Contact for pricing

    Office Space Available For Rent

    Office space for rent at 515 N King St.

    515 N King St, Seguin, TX 78155
    View details
    New Schertz Medical Office Building
    Contact for pricing
    9,010 SF

    New Schertz Medical Office Building

    New 9,010 SF medical office in Schertz, Texas.

    3795 Roy Richard Dr, Schertz, TX
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    Office Space Available For Rent
    Contact for pricing
    12,572 SF

    Office Space Available For Rent

    Office space available for rent in Seguin, Texas.

    515 N King St, Seguin, TX 78155
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    Schertz Office Space For Rent
    Contact for pricing
    902 SF

    Schertz Office Space For Rent

    Office space available for rent in Schertz, Texas.

    5000 Baptist Health Dr, Schertz, TX 78154
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    Schertz Medical Center Office Space
    $32 SF/Yr
    1,250 SF

    Schertz Medical Center Office Space

    New medical development in a rapidly growing area.

    3701 Fm 3009, Schertz, TX 78154
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    Seguin Medical Office Space for Lease
    $18 SF/Yr
    5,400 SF

    Seguin Medical Office Space for Lease

    Prime Medical Office Suites Available in Seguin, TX

    412 King St, Seguin, TX 78155
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    Seguin Medical Office Opportunity
    $18 SF/Yr
    10,200 SF

    Seguin Medical Office Opportunity

    1,200 SF Suite Available in Prime Location

    1405 Highway 123 Byp, Seguin, TX 78155
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    Cibolo Medical Office Space
    Contact for pricing
    6,526 SF

    Cibolo Medical Office Space

    Medical office building in growing Cibolo micro-market.

    580 Cibolo Valley Dr, Cibolo, TX 78108
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    New Braunfels Medical Office Space
    $34 SF/Yr
    15,759 SF

    New Braunfels Medical Office Space

    Prime Medical Office Suites Available in Texas

    711 Klein Rd, New Braunfels, TX 78130
    View details

    Guadalupe County, TX Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Guadalupe County, TX with 32 listings featured on our commercial real estate exchange. The current inventory includes 4,254,766,560 square feet of properties with an estimated lease value of $269 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Guadalupe County, TX begin at $2 SF/Yr, with an average of $17 SF/Yr and extend to $34 SF/Yr.
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    Office properties & Spaces by market

    Browse Office properties & Spaces for Lease Near Guadalupe, TX

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