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Denison, TX Office Spaces for Lease

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30 properties
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Office Suite with Private Entrances
Updated: Sep 30
Office Suite with Private Entrances

214 N Rusk Avenue, Denison, TX 75020

$1,700/Mo
0.06 AC lot
Four offices, a reception area, and a break room with refrigerator
Private side entrances and designated off‑street parking
In Denison’s Historical District, within walking distance of restaurants, coffee bars, and breweries
Brick building constructed in 1995
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Fenced Flex Property with Warehouses
Updated: Aug 5
Fenced Flex Property with Warehouses

514-520 S Armstrong Avenue, Denison, TX 75020

$3,500/Mo
0.53 AC lot
0.525‑acre fenced and gated commercial site
Three buildings, including office and two separate warehouse structures
Office area of approximately 1,104 square feet with two restrooms and a breakroom
Larger warehouse contains approximately 2,100 square feet and has electricity
Roll‑up doors serve both warehouse buildings
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Office Suite with Loft
Office Suite with Loft

110 S Houston Avenue, Denison, TX 75021

$1,200/Mo
0.31 AC lot

Two levels pair an open work area with an upper loft offering additional office space.

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Medical Office Space with Kitchen
Medical Office Space with Kitchen

1725 S Austin Ave, Denison, TX 75020

$1,700/Mo
6,800 sqft

Office space includes a sink, refrigerator, trash compactor, and dedicated kitchen facilities.

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Two-Room Office Suites
Two-Room Office Suites

110 S Houston Avenue, Denison, TX 75021

$400/Mo
0.31 AC lot

Each suite pairs a private office with a connected room, alongside shared building amenities.

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Office Suite with Shared Amenities
Office Suite with Shared Amenities

110 S Houston Avenue, Denison, TX 75021

$600/Mo
0.31 AC lot

A private workspace is complemented by communal reception, kitchen, lounge, and exercise areas.

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Office Suite with Reception Area
Office Suite with Reception Area

1110 S Armstrong Avenue, Denison, TX 75020

$1,500/Mo
0.15 AC lot

The suite includes two restrooms, a break room, and parking serving the property.

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Office Unit with Warehouse Expansion
Office Unit with Warehouse Expansion

2531 W Morton St Unit 3, Denison, TX 75020

$1,100/Mo
600 sqft

Professional office unit with convenient customer parking and an adjacent warehouse available for additional space.

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Updated Office Unit with Breakroom
Updated Office Unit with Breakroom

1725 S Austin Avenue, Denison, TX 75020

$1,700/Mo
0.55 AC lot

The space offers practical support amenities and an ADA-compliant restroom for professional office operations.

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Flex Space with Fenced Yard
Flex Space with Fenced Yard

4109 Parkdale Lane, Denison, TX 75020

$3,000/Mo
0.53 AC lot

Office, showroom, and shop areas support varied commercial operations with vehicle access and outdoor storage.

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Updated Office Unit
Updated Office Unit

205 W Gandy St, Denison, TX 75020

$1,500/Mo
936 sqft

Renovated interior with refreshed finishes and modern lighting supports a professional business setting.

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Office Unit on Morton Street
Office Unit on Morton Street

2531 W Morton Street, Denison, TX 75020

$1,100/Mo
0.36 AC lot

Compact office suite with central HVAC, open parking, and an adjacent warehouse option for additional space.

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Updated Office Unit
Updated Office Unit

205 W Gandy Street, Denison, TX 75020

$1,500/Mo
0.15 AC lot

Recently renovated commercial space with new flooring, lighting, and flexible parking access.

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Streetfront Office Suite
Streetfront Office Suite

2531 W Morton Street 3, Denison, TX 75020

$1,100/Mo
600 sqft

Efficient office space on W Morton Street with convenient customer parking and strong street-level visibility.

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Two-Story Office Building
Two-Story Office Building

101 W US Highway 69, Denison, TX 75021

$1,900/Mo
0.29 AC lot

Flexible commercial space with restrooms on both floors and parking for customers and employees.

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Updated Flex Space
Updated Flex Space

807 S Austin Avenue, Denison, TX 75020

$1,500/Mo
0.09 AC lot

Brick construction, concrete flooring, and an improved restroom support a practical commercial workspace.

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Office Suite with High Visibility
Office Suite with High Visibility

3-2531 W Morton St, Denison, TX 75021

$1,100/Mo
600 sqft

Lease a 600-square-foot office suite on W Morton St with high daily traffic and excellent visibility.

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Second-Floor Church Rental Spaces
Second-Floor Church Rental Spaces

213 N Burnett Avenue, Denison, TX 75020

$10 SF/Yr
0.69 AC lot

Adaptable second-floor suites support offices, classrooms, studios, and meeting uses with shared restrooms and parking.

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Medical Office Space for Lease
Medical Office Space for Lease

5012 S US-75, Denison, TX 75020

$1,251/Mo
120,000 sqft

Medical office space available on US Highway 75 with addresses at 5012 S and 5125 US Highway 75 in Denison, TX.

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Four-Office Office Suite
Four-Office Office Suite

214 N Rusk Avenue, Denison, TX 75020

$1,700/Mo

Updated workspace includes a reception area, break room, and separate side entrances.

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Office Unit in Historic Building
Office Unit in Historic Building

A-110 S Houston Ave, Denison, TX 75021

$600/Mo

A private workspace is complemented by shared visitor areas, a kitchen, and workout equipment.

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Office Unit with Shared Facilities
Office Unit with Shared Facilities

110 S Houston Avenue A, Denison, TX 75021

$600/Mo per office

A private workspace is paired with shared kitchen, entry, waiting, and workout areas.

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Flex Space With Warehouse Buildings
Flex Space With Warehouse Buildings

514-520 S Armstrong Avenue, Denison, TX 75020

$3,500/Mo

Three-building commercial property combines office space with roll-up-door warehouse facilities and secured outdoor area.

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Two-Room Office Suite
Two-Room Office Suite

E-110 S Houston Ave, Denison, TX 75021

$250-$400/Mo

Each suite offers adjoining private rooms and access to shared kitchen and waiting areas.

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Denison, TX Office Spaces Lease Rates & Market Statistics

Browse 30 Office Spaces for lease in Denison, TX on Realmo, a commercial real estate marketplace serving the Denison area. The current inventory totals 131,585 square feet of properties — an average of ~4,400 SF per listing.

Asking lease rates for Office Spaces in Denison start at $3 SF/Yr, average $15.46 SF/Yr, and reach $22 SF/Yr at the top of the market. That's a 7x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $15.46 SF/Yr is 37% below the Texas state average of $24.41 SF/Yr.

Denison accounts for 31% of the 98 office spaces currently available across Grayson County, where nearby markets include Sherman and Van Alstyne. By space type, the market includes 25 office units, 6 creative space listings and 5 medical office space listings — medical office space options typically offer the lowest entry point, while office units command the highest rates.

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