Denison, TX Office Spaces for Rent & Lease

Updated: Aug 5

Fenced Flex Property with Warehouses

514-520 S Armstrong Avenue, Denison, TX 75020

$3,500/Mo

0.53 AC lot

0.525‑acre fenced and gated commercial site
Three buildings, including office and two separate warehouse structures
Office area of approximately 1,104 square feet with two restrooms and a breakroom
Larger warehouse contains approximately 2,100 square feet and has electricity
Roll‑up doors serve both warehouse buildings

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Updated: Jul 11

Updated Office Unit with Breakroom

1725 S Austin Avenue, Denison, TX 75020

$1,700/Mo

0.55 AC lot

Breakroom includes sink, refrigerator, and trash compactor
ADA‑compliant restroom included
Central air conditioning and multiple heating systems
Brick and fiber cement construction
Laminate and linoleum flooring

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Office Building with Natural Light

1331 Memorial Drive, Denison, TX 75020

$4,000/Mo

2.87 AC lot

Flexible commercial layout with finished bathrooms, private rooms, open areas, and a secured concrete room with steel doors.

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Medical Office Space with Kitchen

1725 S Austin Ave, Denison, TX 75020

$1,700/Mo

6,800 sqft

Office space includes a sink, refrigerator, trash compactor, and dedicated kitchen facilities.

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Two-Story Office Building

101 W US Highway 69, Denison, TX 75021

$1,900/Mo

0.29 AC lot

Flexible commercial space with restrooms on both floors and parking for customers and employees.

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Flex Space with Fenced Yard

4109 Parkdale Lane, Denison, TX 75020

$3,000/Mo

0.53 AC lot

Office, showroom, and shop areas support varied commercial operations with vehicle access and outdoor storage.

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Office Unit on Morton Street

2531 W Morton Street, Denison, TX 75020

$1,100/Mo

0.36 AC lot

Compact office suite with central HVAC, open parking, and an adjacent warehouse option for additional space.

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Updated Office Unit

205 W Gandy St, Denison, TX 75020

$1,500/Mo

936 sqft

Renovated interior with refreshed finishes and modern lighting supports a professional business setting.

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Updated Flex Space

807 S Austin Avenue, Denison, TX 75020

$1,500/Mo

0.09 AC lot

Brick construction, concrete flooring, and an improved restroom support a practical commercial workspace.

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Office Suite with Reception Area

1110 S Armstrong Avenue, Denison, TX 75020

$1,500/Mo

0.15 AC lot

The suite includes two restrooms, a break room, and parking serving the property.

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Office Suite with High Visibility

3-2531 W Morton St, Denison, TX 75021

$1,100/Mo

600 sqft

Lease a 600-square-foot office suite on W Morton St with high daily traffic and excellent visibility.

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Updated Office Unit

205 W Gandy Street, Denison, TX 75020

$1,500/Mo

0.15 AC lot

Recently renovated commercial space with new flooring, lighting, and flexible parking access.

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Second-Floor Church Rental Spaces

213 N Burnett Avenue, Denison, TX 75020

$10 SF/Yr

0.69 AC lot

Adaptable second-floor suites support offices, classrooms, studios, and meeting uses with shared restrooms and parking.

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Medical Office Space for Lease

5012 S. & 5125 US-75, Denison, TX 75020

$1,251/Mo

120,000 sqft

Medical office space available on US Highway 75 with addresses at 5012 S and 5125 US Highway 75 in Denison, TX.

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Updated Retail Space with Lobby

714 W Chestnut Street, Denison, TX 75020

$11 SF/Yr

0.69 AC lot

Refreshed interiors, street-facing windows, and customer parking support office or retail occupancy in Denison’s downtown district.

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Newly Renovated Executive Suite

231 W Main Street, Denison, TX 75020

$5,000/Mo

1.50 AC lot

Newly renovated office suite building with central HVAC, public utilities, and ample parking in a downtown Denison streetscape.

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Streetfront Office Suite

2531 W Morton Street 3, Denison, TX 75020

$1,100/Mo

600 sqft

Efficient office space on W Morton Street with convenient customer parking and strong street-level visibility.

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Flex Space With Warehouse Buildings

514-520 S Armstrong Avenue, Denison, TX 75020

$3,500/Mo

Three-building commercial property combines office space with roll-up-door warehouse facilities and secured outdoor area.

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Office Building with Secure Imaging Room

1331 Memorial Drive, Denison, TX 75020

$4,000/Mo

Expansive office building with framed interiors, modern lighting, finished bathrooms, and a former imaging room with steel doors.

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Second-Floor Office Units

213 N Burnett Avenue, Denison, TX 75020

$10 SF/Yr

Adaptable rental suites offer room for offices, classrooms, studios, or meetings with shared restrooms and parking available.

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Renovated Open-Plan Retail Space

103-231 W Main St, Denison, TX 75021

$5,000/Mo

Flexible commercial space offers pedestrian exposure, executive suites, and neighboring office accommodations within the same building.

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Denison Office Space For Lease

101 N Hwy 75, Denison, TX 75020

Contact for pricing

6,289 sqft 0.96 AC lot

Office suite for lease with high visibility and traffic.

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Medical Office Space For Lease

3025 FM691, Denison, TX

Contact for pricing

1,477 sqft 5.76 AC lot

Class-A medical office space on Texoma Medical Center campus.

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Endcap Retail/Office Suite

102-320 S Mirick Ave, Denison, TX 75020

$1,200/Mo

End unit suite with a connecting door, previously used as a beauty salon, suitable for office or retail.

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Denison, TX Office Spaces Lease Rates & Market Statistics

Browse 25 Office Spaces for lease in Denison, TX on Realmo, a commercial real estate marketplace serving the Denison area. The current inventory totals 136,702 square feet of properties — an average of ~5,450 SF per listing.

Asking lease rates for Office Spaces in Denison start at $3 SF/Yr, average $13.89 SF/Yr, and reach $22 SF/Yr at the top of the market. That's a 7x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $13.89 SF/Yr is 42% below the Texas state average of $23.86 SF/Yr.

Denison accounts for 23% of the 108 office spaces currently available across Grayson County, where nearby markets include Sherman and Van Alstyne. By space type, the market includes 20 office units and 6 medical office space listings — medical office space options typically offer the lowest entry point, while office units command the highest rates.