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    South Carolina Office Buildings for Lease

    82 results
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    Pawleys Island Professional Office Building
    $4,125 /Mo
    16,000 SF

    Pawleys Island Professional Office Building

    160 Willbrook Blvd, Pawleys Island, SC 29585

    Professional office building in Pawleys Island with flexible suite sizes.

    • Excellent location in the heart of Pawleys Island.
    • Flexible suite sizes with dedicated entries: 16,000 SF, 5,000 SF, 4,290 SF, or 2,250 SF.
    • Abundant on‑site parking with 93 spaces.
    • Like‑new delivery with landlord improvements, including new HVAC systems and roof replacement.
    • Tenant Improvement Allowance available, dependent on lease term and use.
    Last Update: Sep 22
    View details
    Pawleys Island Office For Lease
    $5,754 /Mo
    3,002 SF

    Pawleys Island Office For Lease

    38 Blackgum Rd, Pawleys Island, SC 29585

    3002 SF office space with bank components in place.

    • Former bank with existing infrastructure like a drive‑through and vault.
    • 3002 SF office space suitable for various businesses.
    • Includes 4 executive offices and a conference room.
    • Features a server room with dedicated mini‑split cooling.
    • Equipped with central heating and air conditioning.
    Last Update: Oct 21
    View details
    Free Standing Office Building For Lease
    $3,000 /Mo
    1,260 SF

    Free Standing Office Building For Lease

    Well-maintained 1,260 SF office building available for lease.
    516 29Th Ave N, Myrtle Beach, SC 29577
    View details
    North Augusta Commercial Building For Lease
    $16 SF/Yr
    7,100 SF

    North Augusta Commercial Building For Lease

    Office and warehouse spaces available in North Augusta, South Carolina.
    1305 Georgia Ave, North Augusta, SC 29841
    View details
    New Custom-Built Office Suites
    $1,500 /Mo
    3,049 SF

    New Custom-Built Office Suites

    Pre-leasing custom office suites with private entrances, available Q2 2026.
    101 Ladys Is Cmns, Ladys Island, SC 29907
    View details
    Prime Duncan Office Building
    Contact for pricing
    51,914 SF

    Prime Duncan Office Building

    51,914 SF Office Space For Sale
    2153 E Main St Duncan, SC 29334, Duncan, SC 29334
    View details
    Greenville Office Space Available
    $3,250 /Mo
    3,250 SF

    Greenville Office Space Available

    3250 SF Office, Modified Gross Lease
    86 Allen St, Greenville, SC 29605
    View details
    Spartanburg Office Building For Lease
    $15 SF/Yr
    1,800 SF

    Spartanburg Office Building For Lease

    1800 SF Office, Prime Location
    1971 S Pine St, Spartanburg, SC 29302
    View details
    Medical/Professional Office Near Conway Hospital
    $6,251 /Mo
    5,246 SF

    Medical/Professional Office Near Conway Hospital

    Medical/professional office building near Conway Medical Center with customizable space.
    8028 Myrtle Trace Dr, Conway, SC 29526
    View details
    Remodeled Office Building For Rent
    $1,800 /Mo
    1,874 SF

    Remodeled Office Building For Rent

    Remodeled office building with high traffic count in Dillon, SC.
    1013 Highway 301 N, Dillon, SC 29536
    View details
    Prime Mt. Pleasant Office Space
    $28 SF/Yr
    30,184 SF

    Prime Mt. Pleasant Office Space

    Class A Office Suites, 13 Spaces Available
    501 Wando Park Blvd, Mount Pleasant, SC 29464
    View details
    Spacious Office Building For Lease
    $5,900,000
    60,000 SF

    Spacious Office Building For Lease

    Single-level office space with flexible layout and ample parking.
    3245 Platt Spg Rd, West Columbia, SC
    View details
    Medical Office Space Available
    Contact for pricing
    39,722 SF

    Medical Office Space Available

    Accessible medical office space in a growing Columbia corridor.
    3221 Sunset Blvd, West Columbia, SC 29169
    View details
    Office Building Near I-77
    Contact for pricing
    105,844 SF

    Office Building Near I-77

    Two-story office building with ample parking and easy highway access.
    2341 Deerfield Dr, Fort Mill, SC 29715
    View details
    Office/Restaurant Building Near USC Stadium
    $299,000
    3,054 SF

    Office/Restaurant Building Near USC Stadium

    3,054 SF building near USC Stadium available for rent.
    1115 Bluff Industrial Blvd, Columbia, SC 29201
    View details
    Industrial Outdoor Storage with Office
    $50,000

    Industrial Outdoor Storage with Office

    10 acre industrial site with 7,040 SF office.
    625 Five Chop Rd, Orangeburg, SC 29115
    View details
    North Charleston Office Building Available
    $17 SF/Yr
    6,158 SF

    North Charleston Office Building Available

    One-story office building with contemporary design and ample parking.
    4995 Lacross Rd, North Charleston, SC
    View details
    Freestanding Office Building For Lease
    $20 SF/Yr
    3,400 SF

    Freestanding Office Building For Lease

    Two-story office property in a rapidly developing commercial corridor.
    890 Johnnie Dodds Blvd, Mount Pleasant, SC 29464
    View details
    Office/Flex Building with Warehouse
    $6,000,000
    31,835 SF

    Office/Flex Building with Warehouse

    Single-story office/flex building with warehouse and ample parking.
    127 Tanner Rd, Greenville, SC 29607
    View details
    Two-Story Office Building Available
    Contact for pricing
    5,500 SF

    Two-Story Office Building Available

    Two-story office building with ample parking and multiple access points.
    501 Roper Mountain Rd, Greenville, SC 29615
    View details
    West Ashley Freestanding Building
    $22 SF/Yr
    8,729 SF

    West Ashley Freestanding Building

    8,729 SF building on 3.53 acres in West Ashley.
    1025 Sam Rittenberg Blvd, Charleston, SC 29407
    View details
    Office Property Near Downtown Columbia
    Contact for pricing
    8,181 SF

    Office Property Near Downtown Columbia

    Office and flex spaces available near I-20 and I-26.
    720 Gracern Rd, Columbia, SC 29210
    View details
    Class A Office Space Available
    $59 SF/Yr
    3,700 SF

    Class A Office Space Available

    Class A office space for rent in Mount Pleasant.
    Bridgeside Blvd, Mount Pleasant, SC 29464
    View details
    Class A Office High-Rise
    Contact for pricing
    20,048 SF

    Class A Office High-Rise

    Class A office space in Columbia's Central Business District.
    1441 Main St, Columbia, SC 29201
    View details

    South Carolina Office buildings Leasing Opportunities Market Analysis

    Explore Office buildings leasing options in South Carolina with 300 listings featured on our commercial real estate exchange. The current inventory includes 24,890,497,630 square feet of properties with an estimated lease value of $5,599 /Mo.

    Estimated lease rates for Office buildings in South Carolina begin at $3 SF/Yr, with an average of $101 SF/Yr and extend to $3,000 /Mo.
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