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South Carolina Office Buildings for Lease

85 results
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Aiken Commercial Office Building ForRent
$4,758 / Mo
2,595 SF

Aiken Commercial Office Building ForRent

160 Waterloo St SW, Aiken, SC 29801

Commercial office building in a convenient and accessible area.

  • Central location in Aiken with easy access to major roadways and downtown amenities.
  • Ample on‑site parking for employees and visitors.
  • Functional layout with private offices, open work areas, and flexible space.
  • Excellent visibility for businesses.
  • Accessible approach with ramp.
Updated: Mar 6
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Surfside Beach Freestanding Office Building
$2,500 / Mo
1,100 SF

Surfside Beach Freestanding Office Building

825 1St Ave N, Surfside Beach, SC 29575

Freestanding office building for lease in downtown Surfside Beach.

  • Prime location in downtown Surfside Beach, one block from Surfside Drive and near Hwy 17 Business.
  • High traffic area with 32,600 Avg Daily Traffic on US Hwy 17 Bus.
  • Strong demographics with a permanent population of 64,683 within a 5‑mile radius.
  • Well‑equipped 1,100 SF office space with reception area, four offices, restrooms, kitchen, and storage.
  • Excellent accessibility from Hwy 17 Business and proximity to the Atlantic Ocean (less than 1 mile).
Updated: Feb 27
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Remodeled Office Building For Rent
$1,800 / Mo
1,874 SF

Remodeled Office Building For Rent

Remodeled office building with high traffic count in Dillon, SC.

1013 Highway 301 N, Dillon, SC 29536
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Professional Office Building in Myrtle Beach
$5,000 / Mo
2,230 SF

Professional Office Building in Myrtle Beach

Well-maintained office building in the heart of Myrtle Beach.

607 19Th Ave N, Myrtle Beach, SC 29577
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New Custom-Built Office Suites
$1,500 / Mo
3,049 SF

New Custom-Built Office Suites

Pre-leasing custom office suites with private entrances, available Q2 2026.

101 Ladys Island Cmns, Ladys Island, SC 29907
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Medical/Professional Office Near Conway Hospital
$6,251 / Mo
5,246 SF

Medical/Professional Office Near Conway Hospital

Medical/professional office building near Conway Medical Center with customizable space.

8028 Myrtle Trace Dr, Conway, SC 29526
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Furnished Office Building Sublease Opportunity
$24 SF/Yr
78,394 SF

Furnished Office Building Sublease Opportunity

Well-appointed, fully furnished office building available for sublease on Daniel Island.

125 Fairchild St, Charleston, SC 29492
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Class B Office Space Available
$14 SF/Yr
16,966 SF

Class B Office Space Available

Multi-tenant office building with interstate visibility and ample parking.

1628 Browning Rd, Columbia, SC 29210
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Class A Office Space
$615 / Mo

Class A Office Space

Class A office suites for lease in North Myrtle Beach.

1016 2Nd Ave North, North Myrtle Beach, SC 29582
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Modern Office Space Available
$500 / Mo

Modern Office Space Available

Updated office space with 9 offices, conference room, and breakroom.

521 N Mcduffie St, Anderson, SC 29621
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Class A Office Space Available
$525 / Mo

Class A Office Space Available

Class A office building in Myrtle Beach's business district.

2411 N Oak St, Myrtle Beach, SC 29577
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Freestanding Office Building For Lease
$20 SF/Yr
4,200 SF

Freestanding Office Building For Lease

Single-story office building in Forest Acres with ample parking.

9 Calendar Ct, Columbia, SC 29206
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Spartanburg CBD Office Space
$1,000 / Mo
760 SF

Spartanburg CBD Office Space

Multi-tenant office building in Spartanburg's central business district.

389 E Henry St, Spartanburg, SC 29302
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Single Story Office Building
$15 SF/Yr
7,764 SF

Single Story Office Building

106,649 SF single-story office building available for lease.

1100 Brookfield Blvd, Greenville, SC 29607
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Class A Office Space
$25 SF/Yr
3,774 SF

Class A Office Space

Class A office building for lease in Buckwalter Place.

1 Carecore Dr, Bluffton, SC
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North Charleston Office Building Available
$17 SF/Yr
6,158 SF

North Charleston Office Building Available

One-story office building with contemporary design and ample parking.

4995 Lacross Rd, North Charleston, SC
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Class A Office in Columbia
$21 SF/Yr
87,249 SF

Class A Office in Columbia

Class A office building in Carolina Research Park for lease.

7 Technology Cir, Columbia, SC 29203
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Class A Medical Office Building
$28 SF/Yr
14,084 SF

Class A Medical Office Building

Renovated medical/office building in Mt. Pleasant, ample parking.

1200 Innovation Way, Mount Pleasant, SC 29466
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Class A Office Building For Rent
$18 SF/Yr
57,000 SF

Class A Office Building For Rent

Unique atrium-style office building with suites available for immediate occupancy.

115 Atrium Way, Columbia, SC 29223
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Farrow Road Office Building
$20 SF/Yr
57,375 SF

Farrow Road Office Building

Two-story office building with high visibility and ample parking.

101 Business Park Blvd, Columbia, SC 29223
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Class-A Suburban Office Building
$19 SF/Yr
108,000 SF

Class-A Suburban Office Building

108,000 SF office building near downtown Columbia for lease.

140 Stoneridge Dr, Columbia, SC 29210
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Downtown Columbia Office Space Available
$17 SF/Yr
9,000 SF

Downtown Columbia Office Space Available

Office building in historic district with parking and flexible layout.

1500 Richland St, Columbia, SC 29201
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Cayce Office/Medical Space Available
$20 SF/Yr
5,670 SF

Cayce Office/Medical Space Available

5,670 SF building suitable for office or medical use.

1105 State St, Cayce, SC 29033
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Historic Downtown Charleston Office Space
$30 SF/Yr
2,851 SF

Historic Downtown Charleston Office Space

Recently renovated office space in historic downtown Charleston.

11 Broad St, Columbia, SC 29203
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South Carolina Office buildings Leasing Opportunities Market Analysis

Explore Office buildings leasing options in South Carolina with 301 listings featured on our commercial real estate exchange. The current inventory includes 31,324,309,630 square feet of properties with an estimated lease value of $734 /Mo.

Estimated lease rates for Office buildings in South Carolina begin at $5 SF/Yr, with an average of $21 SF/Yr and extend to $39 SF/Yr.
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