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    South Carolina Office Buildings for Lease

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    Greenville, SC Columbia, SC Charleston, SC Myrtle Beach, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Mount Pleasant, SC
    178 properties
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    Downtown Greenville Office Space Available
    Downtown Greenville Office Space Available

    101 North Main Street, Greenville, SC 29601

    $38.50 SF/Yr
    11,085 sqft

    Office space for rent in downtown Greenville with amenities.

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    Renovated Class A Office Building
    Renovated Class A Office Building

    4055 Faber Place Drive, North Charleston, SC 29405

    $30 SF/Yr
    1,947 sqft

    Three-story office building with high-end finishes, available April 2026.

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    Class A Medical Office Building
    Class A Medical Office Building

    1200 Innovation Way, Mount Pleasant, SC 29466

    $28 SF/Yr
    14,084 sqft

    Renovated medical/office building with ample parking in Mt. Pleasant.

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    Class A Office Building
    Class A Office Building

    1103 48th Avenue North, Myrtle Beach, SC 29577

    $28.50 SF/Yr
    8,209 sqft

    New Class A office space available for lease in Myrtle Beach.

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    Class A Office Space Available
    Class A Office Space Available

    4401 Leeds Avenue, North Charleston, SC 29405

    $34.50 SF/Yr
    8,452 sqft

    Four-story, 102,024 SF Class A office building for lease.

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    Medical Office Park Buildings
    Medical Office Park Buildings

    3700 Forest Dr, Columbia, SC 29204

    $22 SF/Yr
    150,000 sqft

    Two office/medical buildings comprise an approximately 150,000 RSF park on Forest Drive.

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    Class A Office Space
    Class A Office Space

    100 Calhoun Street, Charleston, SC 29401

    $43 SF/Yr
    9,675 sqft

    Multi-tenant office building in Charleston's Historic District.

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    Professional Office Suite
    Professional Office Suite

    1101 Johnson Avenue Unit 302, Myrtle Beach, SC 29577

    $27 SF/Yr
    43,323 sqft

    Professional office space in The Offices at Market Common, located between Highway 17 Business and Highway 17 Bypass.

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    Class A Medical Office Space
    Class A Medical Office Space

    655 Scholar Way, Summerville, SC 29486

    $37 SF/Yr
    12,000 sqft

    Class A medical/general office space in Nexton mixed-use development.

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    Downtown Columbia Office Space Available
    Downtown Columbia Office Space Available

    1333 Main Street, Columbia, SC 29201

    $21.75 SF/Yr
    17,594 sqft

    Prime office space for rent in downtown Columbia.

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    Greenville Office Space For Rent
    Greenville Office Space For Rent

    1 Marcus Drive, Greenville, SC 29615

    $16.50 SF/Yr
    13,566 sqft

    Office building with easy access to major roads and downtown.

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    Columbia Office Building For Lease
    Columbia Office Building For Lease

    1628 Browning Road, Columbia, SC 29210

    $15.75 SF/Yr
    24,683 sqft 4.00 AC lot

    Class B office space with interstate visibility and modern amenities.

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    Class A Office Space Available
    Class A Office Space Available

    1400 Browning Road, Columbia, SC 29210

    $20.75 SF/Yr
    35,838 sqft

    Premium office building with high-tech infrastructure and convenient access.

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    Premier Office Complex in Columbia
    Premier Office Complex in Columbia

    300 Arbor Lake Drive, Columbia, SC 29223

    $12.50 SF/Yr
    20,733 sqft

    Centrally located office complex with amenities and interstate visibility.

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    Fully Furnished Office Suite
    Fully Furnished Office Suite

    30 Patewood Drive, Greenville, SC 29615

    $31 SF/Yr
    7,915 sqft

    Fully furnished office suite with on-site fitness center and tenant lounge, offering excellent exposure from I-385.

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    Class-A Suburban Office Building
    Class-A Suburban Office Building

    140 Stoneridge Dr., Columbia, SC 29210

    $19.50 SF/Yr
    108,000 sqft

    108,000 SF office building near downtown Columbia for rent.

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    Greenville Office Building For Rent
    Greenville Office Building For Rent

    84 Villa Road, Greenville, SC 29615

    $21.50 SF/Yr
    25,640 sqft 1.00 AC lot

    Up to 25,640 SF available near I-385.

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    Premier Office Complex in Columbia
    Premier Office Complex in Columbia

    200 Arbor Lake Drive, Columbia, SC 29223

    $20 SF/Yr
    58,829 sqft

    Centrally located office complex with amenities and interstate visibility.

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    Prime Office Space Near Museums
    Prime Office Space Near Museums

    301 College St, Greenville, SC 29601

    $28 SF/Yr
    130,000 sqft

    Up to 130,000 SF available near Greenville's cultural hub.

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    Furnished Office Building Sublease Opportunity
    Furnished Office Building Sublease Opportunity

    125 Fairchild Street, Charleston, SC, USA, Charleston, SC 29492

    $24 SF/Yr
    78,394 sqft

    Well-appointed, fully furnished office building available for sublease.

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    Office Units With Suite Options
    Office Units With Suite Options

    402 Cane Creek Landing Road, Seneca, SC 29672

    $26.26-$74.38 SF/Yr

    Flexible leasing includes private offices, floor suites, and full-building occupancy with shared conference and reception areas.

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    Suburban Office Park in Greenville
    Suburban Office Park in Greenville

    124 Verdae Blvd, Greenville, SC 29607

    $22.50 SF/Yr
    164,299 sqft

    Office park in prime business district near shopping and restaurants.

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    Greenville Office Space for Lease
    Greenville Office Space for Lease

    2000 Wade Hampton Boulevard, Greenville, SC 29615

    $19 SF/Yr
    188,900 sqft

    Up to 188,900 SF available, near Downtown Greenville.

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    Class A Office Downtown Charleston
    Class A Office Downtown Charleston

    525 East Bay Street, Charleston, SC 29403

    $39 SF/Yr
    14,515 sqft

    Class A office space for rent in downtown Charleston.

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