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    Pickens County, SC Mixed-use Properties for Sale

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    Columbia, SC Greenville, SC Spartanburg, SC
    Liberty SC Corner Commercial Lot
    $374,000
    5.00 Acres

    Liberty SC Corner Commercial Lot

    Ruhamah Road, Liberty, SC 29657

    5 acre corner lot ideal for commercial development.

    • Prime corner lot with high visibility and accessibility.
    • Strategic location suitable for commercial, retail, professional, or mixed‑use development.
    • Located in Upstate South Carolina, centrally positioned between Charlotte and Atlanta.
    • Approximately 5 acres with over 1,000 feet of combined road frontage.
    • Proximity to Industrial Commerce Park indicating future economic development.
    Updated: May 19
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    2,100 SF Industrial Land
    $599,000
    2,100 SF

    2,100 SF Industrial Land

    2227 Farrs Bridge Rd, Easley, SC 29640

    ±2100 SF metal building w/office

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    Based on your search, we've compiled 28 Potential Opportunities for your consideration. Besides 2 Active listings in Pickens County, SC, we suggest exploring several alternatives: similar 22 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Land in Greenville, SC
    $1,800,000
    2,500 SF

    Prime Land in Greenville, SC

    11+/- acre property ideal for development in a growing corridor.

    3900 Highway 153, Greenville, SC 29611
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    Prime Greenville Commercial Corner Lot
    $1,400,000
    5,000 SF

    Prime Greenville Commercial Corner Lot

    High-visibility corner lot near downtown Greenville, ideal for development.

    Poinsett Highway, Greenville, SC 29609
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    Prime Greenville Commercial Corner Lot
    $1,400,000
    10,000 SF

    Prime Greenville Commercial Corner Lot

    High-visibility mixed-use property near downtown Greenville with development potential.

    Poinsett Highway, Greenville, SC 29609
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    Prime Downtown Greenville Land
    $450,000
    0.15 Acres

    Prime Downtown Greenville Land

    Construction-ready lot near downtown Greenville with street frontage and alley access.

    15 Toy Street, Greenville, SC 29601
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    Off-Market Properties in Pickens County, SC

    Consider similar Off-Market properties in Pickens County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    104 Main St
    STORE/OFFICE (MIXED USE)
    6,240 SF
    Estimated value
    $500,000

    104 Main St, Easley, SC 29640-2078

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    405 College Ave
    OFFICE/RESIDENTIAL (MIXED USE)
    185,383 SF Lot: 2.52 Acres
    Estimated value
    $82,500,000

    405 College Ave, Clemson, SC 29631-2918

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    2510 Walhalla Hwya
    STORE/OFFICE (MIXED USE)
    7,186 SF Lot: 2.73 Acres
    Value Estimation by Request

    2510 Walhalla Hwya, Pickens, SC 29671-8706

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    900 Main St
    STORE/OFFICE (MIXED USE)
    89,788 SF Lot: 5.04 Acres
    Estimated value
    $1,140,000

    900 Main St, Easley, SC 29640-3176

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    100 Main St Ste A
    OFFICE/RESIDENTIAL (MIXED USE)
    5,844 SF
    Estimated value
    $710,000

    100 Main St Ste A, Easley, SC 29640-2079

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    205 Main St Ste A
    OFFICE/RESIDENTIAL (MIXED USE)
    7,636 SF
    Estimated value
    $545,000

    205 Main St Ste A, Pickens, SC 29671-2811

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    116 Main St
    OFFICE/RESIDENTIAL (MIXED USE)
    5,980 SF
    Estimated value
    $585,000

    116 Main St, Easley, SC 29640-2078

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    101 Market St
    STORE/OFFICE (MIXED USE)
    12,148 SF Lot: 0.31 Acres
    Estimated value
    $1,140,000

    101 Market St, Clemson, SC 29631-2164

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    109 Main St, Unit A
    OFFICE/RESIDENTIAL (MIXED USE)
    8,122 SF
    Estimated value
    $685,000
    Unit A

    109 Main St, Pickens, SC 29671-2281

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    221 Main St
    OFFICE/RESIDENTIAL (MIXED USE)
    6,466 SF Lot: 0.08 Acres
    Value Estimation by Request

    221 Main St, Easley, SC 29640-2040

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    141 Thomas Grn Blvd
    STORE/OFFICE (MIXED USE)
    13,930 SF Lot: 0.33 Acres
    Estimated value
    $1,285,000

    141 Thomas Grn Blvd, Clemson, SC 29631-2166

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    136 Front St Sta, Unit A
    OFFICE/RESIDENTIAL (MIXED USE)
    5,040 SF
    Estimated value
    $520,000
    Unit A

    136 Front St Sta, Liberty, SC 29657-1137

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    1070 Tiger Blvd
    STORE/OFFICE (MIXED USE)
    3,761 SF Lot: 0.43 Acres
    Value Estimation by Request

    1070 Tiger Blvd, Clemson, SC 29631-1422

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    100 Liberty Dr
    OFFICE/RESIDENTIAL (MIXED USE)
    10,473 SF Lot: 0.61 Acres
    Estimated value
    $855,000

    100 Liberty Dr, Clemson, SC 29631-1615

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    405 Main St
    STORE/OFFICE (MIXED USE)
    4,167 SF
    Value Estimation by Request

    405 Main St, Easley, SC 29640-2969

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    6404 Calhoun Memorial Hwy
    STORE/OFFICE (MIXED USE)
    5,220 SF Lot: 0.71 Acres
    Value Estimation by Request

    6404 Calhoun Memorial Hwy, Easley, SC 29640-3683

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    4237 Calhoun Memorial Hwy
    OFFICE/RESIDENTIAL (MIXED USE)
    2,026 SF Lot: 7.56 Acres
    Value Estimation by Request

    4237 Calhoun Memorial Hwy, Easley, SC 29640-9073

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    379 Old Greenville Hwy Ste, Unit 101
    STORE/OFFICE (MIXED USE)
    8,014 SF Lot: 1.07 Acres
    Estimated value
    $1,040,000
    Unit 101

    379 Old Greenville Hwy Ste, Clemson, SC 29631-3156

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    112 Main St Sta, Unit A
    OFFICE/RESIDENTIAL (MIXED USE)
    7,559 SF
    Estimated value
    $585,000
    Unit A

    112 Main St Sta, Pickens, SC 29671-2221

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    114 Main St
    OFFICE/RESIDENTIAL (MIXED USE)
    4,536 SF
    Value Estimation by Request

    114 Main St, Easley, SC 29640-2078

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    309 Main St
    Individual retail properties
    11,000 SF
    Value Estimation by Request

    309 Main St, Pickens, SC 29671

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    114 Earle St
    Restaurants
    253,000 SF
    Value Estimation by Request

    114 Earle St, Clemson, SC 29631

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    Pickens County, SC Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 24 mixed-use properties for sale in Pickens County, SC on our real estate platform. These investment opportunities span a total of 2,100 square feet of properties for sale, with an estimated market value of $599,000.

    Sale prices for multi use buildings in Pickens County, SC start at $599,000, averaging $599,000, and reaching up to $599,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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