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San Mateo County, CA Mixed-use Properties for Sale

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120 results
Mixed-Use Property in Mission District
$3,750,000
4,302 SF

Mixed-Use Property in Mission District

3265 22nd Street, San Francisco, CA 94110

Well-maintained mixed-use property with retail and residential units in San Francisco.

  • Prime Mission District location, steps from City College Mission Campus, restaurants, shops, and public transit.
  • Stable income from fully occupied residential units (three 1BD/1BA and one 2BD/1BA).
  • Two established retail tenants on the ground floor: a popular cafe and a neighborhood grocery store.
  • Well‑maintained 3‑story mixed‑use property.
  • Strong history of full occupancy in residential units.
Updated: Oct 9, 2025
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San Francisco Mixed-Use Trophy Asset
$18,000,000
3,356 SF

San Francisco Mixed-Use Trophy Asset

3516-3518 Sacramento Street, San Francisco, CA 94118

Rare mixed-use property with income and residential development potential.

  • Exceptional income generation from high‑end commercial tenants ($20,000/month per floor).
  • Approved plans for a two‑story Penthouse residential unit with Golden Gate Bridge views.
  • Prime location at the crest of Sacramento Street, near premier shops and restaurants.
  • Retail space on the ground floor.
  • Immaculately maintained and tastefully updated with a 'no‑expense‑spared' approach.
Updated: Dec 1, 2025
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Remodeled Mixed-Use San Mateo Property
$1,599,000
2,317 SF

Remodeled Mixed-Use San Mateo Property

Versatile live-work opportunity in central Peninsula location.

869 Woodside Way, San Mateo, CA 94401
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Victorian Mixed-Use San Francisco Property
$1,698,000
4,350 SF

Victorian Mixed-Use San Francisco Property

Charming Victorian with commercial space and residential units in San Francisco.

418-422 Haight Street, San Francisco, CA 94117
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Mixed-Use Property in San Francisco
$998,000
2,900 SF

Mixed-Use Property in San Francisco

Mixed-use property with income potential in Excelsior District.

4487-4489 Mission Street, San Francisco, CA 94112
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Mixed-Use Building, Inner Richmond District
$1,899,000
1,980 SF

Mixed-Use Building, Inner Richmond District

Mixed-use property in Inner Richmond near Golden Gate Park.

558-560 Balboa St, San Francisco, CA 94118
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Mixed-Use Property in San Francisco
$1,200,000
3,075 SF

Mixed-Use Property in San Francisco

Mixed-use property with retail space and residential units in San Francisco.

4871 Mission ST, San Francisco, CA 94112
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Mixed-Use Property with Income Potential
$995,000
0.06 Acres

Mixed-Use Property with Income Potential

Multi-unit, mixed-use property in San Francisco with income potential.

345-347 Brazil Avenue, San Francisco, CA 94112
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Boutique Commercial Condo in Japantown
$565,000
521 SF

Boutique Commercial Condo in Japantown

521 SF commercial condo ideal for owner-user in central location.

1600 Webster Street #C2, San Francisco, CA 94115
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Mixed-Use Investment Property, San Francisco
$1,650,000
2,400 SF

Mixed-Use Investment Property, San Francisco

Two-unit mixed-use property in Laurel Heights neighborhood.

2843 Geary, San Francisco, CA 94118
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Updated Mixed-Use Building Near Civic
$3,680,000
13,500 SF

Updated Mixed-Use Building Near Civic

Three-level mixed-use building near transportation and amenities.

1118 Howard Street, San Francisco, CA 94103
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West Portal Mixed-Use Investment
$6,950,000
5,972 SF

West Portal Mixed-Use Investment

Prime mixed-use property in San Francisco's West Portal neighborhood.

24 West Portal Avenue, San Francisco, CA 94127
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Iconic Castro Bar Investment Opportunity
$6,800,000
6,032 SF

Iconic Castro Bar Investment Opportunity

Landmark building with established tenants in prime San Francisco location.

292 Noe Street, San Francisco, CA 94114
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San Mateo Mixed-Use Building
$2,200,000
5,005 SF

San Mateo Mixed-Use Building

Two-story building near Downtown San Mateo with flexible options.

709 B Street, San Mateo, CA 94401
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Menlo Park Mixed-Use Investment
$6,700,000
9,187 SF

Menlo Park Mixed-Use Investment

Mixed-use property with office and live/work suites in Menlo Park.

1800 El Camino Real, Menlo Park, CA 94025
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San Francisco Mixed-Use Investment Property
$1,650,000
0.02 Acres

San Francisco Mixed-Use Investment Property

Mixed-use property in San Francisco's Chinatown with retail and residential.

550-552 Grant Avenue, San Francisco, CA 94108
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SOMA Mixed-Use Work/Live Building
$1,200,000
3,750 SF

SOMA Mixed-Use Work/Live Building

Two-unit mixed-use building in San Francisco's SOMA neighborhood.

22-24 Russ Street, San Francisco, CA 94103
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Versatile Mixed-Use Industrial Warehouse
$2,125,000
9,770 SF

Versatile Mixed-Use Industrial Warehouse

Mixed-use industrial warehouse in San Francisco's Lower Nob Hill.

934 Larkin Street, San Francisco, CA 94109
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Mixed-Use Property in Bayview
$1,390,000
3,150 SF

Mixed-Use Property in Bayview

Versatile mixed-use property with income potential in a vibrant location.

6246 3rd St, San Francisco, CA 94124
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Versatile Mixed-Use Industrial Warehouse
$2,125,000

Versatile Mixed-Use Industrial Warehouse

Mixed-use industrial warehouse in San Francisco's Lower Nob Hill area.

934 Larkin Street, San Francisco, CA 94109
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Union Street Mixed-Use Building
$4,100,000
7,800 SF

Union Street Mixed-Use Building

Four-story mixed-use building in Cow Hollow with Golden Gate views.

2250 Union St, San Francisco, CA 94123
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Renovated Mixed-Use Building For Sale
$5,950,000
11,500 SF

Renovated Mixed-Use Building For Sale

Corner building with retail and office spaces in high-traffic location.

1311 23rd Avenue, San Francisco, CA 94122
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SOMA Mixed-Use Work/Live Building
$1,200,000
3,750 SF

SOMA Mixed-Use Work/Live Building

Two-unit mixed-use building in San Francisco's SOMA neighborhood.

22 Russ Street, San Francisco, CA 94103
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Mission District Assemblage Opportunity
Contact for pricing
65,174 SF

Mission District Assemblage Opportunity

Two-parcel assemblage in vibrant Mission District with mixed-use potential.

3550 Cesar Chavez, San Francisco, CA 94110
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San Mateo County, CA Mixed-Use Properties Investment Opportunities Market Analysis

Explore 120 mixed-use properties for sale in San Mateo County, CA, showcased through 120 active listings on our real estate platform. These investment opportunities span a total of 46,556,552 square feet of properties for sale, with an estimated market value of $213,049,000.

Sale prices for multi use buildings in San Mateo County, CA start at $90,000, averaging $755,492, and reaching up to $18,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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