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    San Diego County, CA Mixed-use Properties for Sale

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    Mixed-Use Property with Residence
    Updated: Sep 25
    Mixed-Use Property with Residence

    2971 Imperial Avenue, San Diego, CA 92102

    $1,080,000
    1,775 sqft 0.13 AC lot
    Remodeled detached residence with 3 bedrooms and 2.5 bathrooms
    Separate commercial building faces Imperial Avenue
    Approximately 5,600‑square‑foot lot zoned CN‑1‑3
    Complete Communities Housing Solutions Tier 3 area; qualifying projects may offer up to 6.5 FAR
    Covered patio and gated driveway with alley access
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    Mixed-Use Building with Retail Space
    Updated: Oct 16
    Mixed-Use Building with Retail Space

    3580 Adams Ave, San Diego, CA 92116

    $2,600,000
    3,690 sqft 0.15 AC lot
    Five apartments: three 1 Bed / 1 Bath units, one studio, and one 2 Bed / 1 Bath unit
    Approximately 2,000 SF of retail space with a bathroom
    3,690 square feet of total property area
    53' x 123' lot with alley access
    Five or more parking spaces
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    Upgraded Mixed-Use Property
    Upgraded Mixed-Use Property

    110 Maple, San Diego, CA 92103

    $4,850,000
    3,750 sqft 0.13 AC lot

    Five-unit corner asset combines professional office space with remodeled residential units and shared landscaped courtyard.

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    Mixed-Use Property with Residence
    Mixed-Use Property with Residence

    2971 Imperial Ave, San Diego, CA 92102

    $1,080,000
    700 sqft 0.13 AC lot

    A detached home and separate Imperial Ave commercial building occupy a gated site with alley access.

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    Mixed-Use Storefront Property
    Mixed-Use Storefront Property

    3275 Euclid, San Diego, CA 92105

    $900,000
    0.11 AC lot

    Corner-lot commercial property with storefront space and separate entrances.

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    Mixed-Use Property with Rental Units
    Mixed-Use Property with Rental Units

    2560-66 Alpine Blvd, Alpine, CA 91901

    $2,300,000
    2.24 AC lot

    Two legal lots combine residential rentals with a commercial storefront along Alpine Boulevard.

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    Five-Suite Mixed-Use Property
    Five-Suite Mixed-Use Property

    2344 Highway 67, Ramona, CA 92065

    $1,295,000
    0.70 AC lot

    The property has commercial zoning, on-site parking, and five suites.

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    El Cajon Redevelopment Opportunity
    El Cajon Redevelopment Opportunity

    939 W Main, El Cajon, CA 92020

    $1,498,800
    3,800 sqft 0.48 AC lot

    Prime corner lot for mixed-use redevelopment in El Cajon.

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    Historic Cedar-Sided Mixed-Use Property
    Historic Cedar-Sided Mixed-Use Property

    780 Main Street, Ramona, CA 92065

    $2,300,000

    Tenant-occupied commercial building with a varied business mix and private lighted parking in Old Town Ramona.

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    Live-Work Space with Two Offices
    Live-Work Space with Two Offices

    2487 Kettner Blvd, San Diego, CA 92101

    $1,149,000
    1,610 sqft 0.02 AC lot

    Commercially zoned property with two kitchens, an upgraded full bath, and mixed-use flexibility for office or residential use.

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    Four-Story Mixed-Use Building
    Four-Story Mixed-Use Building

    920 Kline Street, La Jolla, CA 92037

    $5,800,000
    20,000 sqft 1.50 AC lot

    Mixed retail and office occupancy is supported by an updated elevator and private baths in many suites.

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    Mixed-Use Condominium Property
    Mixed-Use Condominium Property

    120 Ballantyne, El Cajon, CA 92020

    $3,500,000

    Eight residential units and two street-level commercial suites create a combined residential and business configuration.

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    Mixed-Use Commercial Site
    Mixed-Use Commercial Site

    2617 C St, Julian, CA 92036

    $725,000
    0.23 AC lot

    C34-zoned property with parking and a granted variance for office, retail, and industrial uses.

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    Del Mar Coastal Investment Opportunity
    Del Mar Coastal Investment Opportunity

    1237 Camino Del Mar, Del Mar, CA 92014

    $8,000,000
    4,820 sqft

    Two-story commercial building in sought-after beach community.

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    Multi-Parcel Mixed-Use Property
    Multi-Parcel Mixed-Use Property

    Bankhead Spring Old Highway 80, Jacumba, CA 91934

    $1,950,000

    Large acreage with former hospitality improvements, homes, and additional structures across multiple parcels.

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    Landmark Multifamily Property
    Landmark Multifamily Property

    Desert View Tower & 3 Homes, Jacumba, CA 91934

    $1,695,000
    1,800 sqft

    Expansive desert holding with three homes, a historic tower, and distinctive carved-rock grounds.

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    Mixed-Use Property with Retail
    Mixed-Use Property with Retail

    7968-70 BROADWAY, Lemon Grove, CA 91945

    $3,475,000
    4,704 sqft 0.53 AC lot

    Commercially zoned property combines retail space with residential units and a detached house.

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    Mixed-Use Property with Alley Access
    Mixed-Use Property with Alley Access

    1434-44 Garnet Ave, San Diego, CA 92109

    $1,795,000
    1,622 sqft 0.14 AC lot

    Retail/office space includes a detached studio and rear open area.

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    Mixed-Use Retail/Multifamily Investment Opportunity
    Mixed-Use Retail/Multifamily Investment Opportunity

    710-730 8Th St, National City, CA 91950

    $4,200,000
    9,818 sqft 0.61 AC lot

    Mixed-use property with retail and multifamily units, high cap rate.

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    Mixed-Use Property with Retail Frontage
    Mixed-Use Property with Retail Frontage

    3783-89 Park Blvd, San Diego, CA 92103

    $3,750,000
    7,310 sqft

    Eight residences include studios, cottages, and duplex units, with an on-site laundry room serving the property.

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    National City Redevelopment Opportunity
    National City Redevelopment Opportunity

    205 E 8th Street, National City, CA 91950

    $3,200,000
    10,400 sqft 0.24 AC lot

    Mixed-use redevelopment opportunity in downtown National City.

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    Mixed-Use Property with Bar and Residence
    Mixed-Use Property with Bar and Residence

    9141-43 Campo Road, Spring Valley, CA 91977

    $997,500
    4,000 sqft

    Two-parcel commercial property combines an established bar space with an adjoining two-bedroom residence and General Commercial zoning.

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    Corner-Lot Mixed-Use Building
    Corner-Lot Mixed-Use Building

    2754 Imperial Avenue, San Diego, CA 92102

    Contact for pricing
    4,272 sqft 0.13 AC lot

    Private offices, four restrooms, a kitchenette, and on-site parking accommodate flexible commercial occupancy.

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    Mixed-Use Property with Residence
    Mixed-Use Property with Residence

    4741 Point Loma Ave, San Diego, CA 92106

    Contact for pricing
    3,376 sqft

    Three-part configuration combines commercial suites with a two-level upper residence.

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    San Diego County, CA Mixed-Use Properties Market Trends and Statistics

    Explore 80 mixed-use properties for sale in San Diego County, CA, showcased through 80 active listings on our real estate platform. These investment opportunities span a total of 359,181 square feet of properties for sale, with an estimated market value of $129,691,105.

    Sale prices for multi use buildings in San Diego County, CA start at $599,000, averaging $2,646,757, and reaching up to $8,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Featured San Diego County Real Estate Agencies

    Realmo connects you with licensed San Diego County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Century 21 Horizon
    4134 Adams Ave., #101 San Diego, CA 92116
    Phone: 16192805888
    www.century21horizon.com
    The Roby Company
    13410 Pomerado Road Poway, CA 92064
    Phone: 18587488002
    www.therobycompany.com
    Coldwell Banker West
    2300 Boswell Road, Suite 100 Chula Vista, CA 91914
    Phone: 16197372126
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