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San Diego County, CA Mixed-use Properties for Sale

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51 results
Mixed-Use Property Near U.S.-Mexico Border
$4,099,000
0.31 Acres

Mixed-Use Property Near U.S.-Mexico Border

165 W San Ysidro Blvd, San Ysidro, CA 92173

New mixed-use property in San Ysidro, near U.S.-Mexico border.

  • Prime location: Just 1.5 miles from the world's busiest U.S.-Mexico border crossing.
  • New construction (2021) featuring 7 units and 7,989 SF of rentable space.
  • Flexible CC‑3‑4 zoning allows for diverse business uses.
  • Mixed‑use property ideal for owner‑users or investors.
  • Equipped with grease interceptors and elevator service.
Updated: Apr 3
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Fallbrook Multi-Use Opportunity
$999,000
3.25 Acres

Fallbrook Multi-Use Opportunity

5461 Rainbow Creek, Fallbrook, CA 92028

Flexible commercial/residential property near I-15 in Fallbrook, California.

  • Rare multi‑use property suitable for commercial or residential use.
  • Located minutes from the I‑15 corridor, providing convenient access.
  • Property size is over 3 acres, offering privacy and space.
  • Expansive great room adaptable to living room and kitchen.
  • Features 5‑6 private offices easily convertible to bedrooms.
Updated: Mar 22
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Escondido Commercial Asset For Sale
$1,500,000
2,400 SF

Escondido Commercial Asset For Sale

Commercial building in Escondido with redevelopment potential.

1025-29 E Valley Pkwy, Escondido, CA 92025
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Oceanside Mixed-Use Investment Opportunity
$1,800,000
2,369 SF

Oceanside Mixed-Use Investment Opportunity

Mixed-use property near the beach with income potential.

110 S Freeman Street, Oceanside, CA 92054
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Bankers Hill Mixed-Use Opportunity
$2,849,000
3,800 SF

Bankers Hill Mixed-Use Opportunity

Three-story mixed-use building in Bankers Hill with flexible zoning.

2368 2nd AVE, San Diego, CA 92101
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National City Mixed-Use Development Opportunity
$899,999
19,738 SF

National City Mixed-Use Development Opportunity

Three units on a commercially zoned lot for sale.

2641 E 18th Street 45, National City, CA 91950
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Mixed-Use Property Near Downtown
$850,000

Mixed-Use Property Near Downtown

Mixed-use investment property near Downtown San Diego and Petco Park.

2557-59 Imperial Ave, San Diego, CA 92102
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Alpine Mixed-Use Development Opportunity
$3,000,000
6,000 SF

Alpine Mixed-Use Development Opportunity

2.24 acres with commercial, residential, and expansion potential.

2560 ALPINE BLVD 66, Alpine, CA 91901
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San Ysidro Vacant Lot Opportunity
$425,000
4,442.00 Acres

San Ysidro Vacant Lot Opportunity

Vacant lot with residential and commercial zoning in San Ysidro.

N Lane, San Ysidro, CA 92173
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Remodeled Mixed-Use Property in Hillcrest
$1,189,000
1,778 SF

Remodeled Mixed-Use Property in Hillcrest

Upgraded office and retail space in a vibrant San Diego neighborhood.

825-829 Washington St., San Diego, CA 92103
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Versatile Mixed-Use Commercial Property
$1,149,000
1,610 SF

Versatile Mixed-Use Commercial Property

Mixed-use property with office spaces, kitchens, and flex space.

2487 Kettner Blvd, San Diego, CA 92101
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Mixed-Use Development Opportunity, San Diego
$1,890,000
4,569 SF

Mixed-Use Development Opportunity, San Diego

Mixed-use development site with income potential in up-and-coming Encanto.

6365 Imperial Avenue, San Diego, CA 92114
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Landmark Multifamily Investment Opportunity
$4,995,000
5,506 SF

Landmark Multifamily Investment Opportunity

Signature income property in prime San Diego location.

3574 4th Ave. (-80), San Diego, CA 92103
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Multi-Use Property on Greenfield Drive
$1,640,000
6,300 SF

Multi-Use Property on Greenfield Drive

Multi-use property with office, retail, and warehouse space.

1250 Greenfield Dr, El Cajon, CA 92021
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Freestanding Commercial Property on Mission Avenue
$1,600,000
4,599 SF

Freestanding Commercial Property on Mission Avenue

Commercial property with dual storefronts in high-traffic Oceanside location.

1708 - 1710 Mission Avenue, Oceanside, CA 92058
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Downtown San Diego Mixed-Use Building
$7,900,000
29,096 SF

Downtown San Diego Mixed-Use Building

Mixed-use building in downtown San Diego with redevelopment potential.

640 Broadway, San Diego, CA 92101
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Downtown San Diego Corner Unit
$1,149,900

Downtown San Diego Corner Unit

Versatile corner unit in vibrant East Village, San Diego.

875 G St, San Diego, CA 92101
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Leased Multi-Tenant Escondido Asset
$3,950,000
15,806 SF

Leased Multi-Tenant Escondido Asset

100% leased multi-tenant asset in downtown Escondido.

201 E Grand Ave, Escondido, CA 92025
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Multi-Use Property Near I-15
$999,000

Multi-Use Property Near I-15

Flexible commercial/residential property with great room and private offices.

5461 Rainbow Creek Unit Three Legal Lots, Fallbrook, CA 92028
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La Mesa Village Twin-Home
$1,650,000
2,600 SF

La Mesa Village Twin-Home

Craftsman twin-home zoned for residential and commercial use.

8318 Allison, La Mesa, CA 91942
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Mixed-Use Redevelopment Opportunity
$1,688,888

Mixed-Use Redevelopment Opportunity

Prime mixed-use property with redevelopment potential near 3rd Avenue Promenade.

402 Church Ave, Chula Vista, CA 91910
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North Park Mixed-Use Investment Property
$4,495,000
3,360 SF

North Park Mixed-Use Investment Property

Rebuilt mixed-use property with restaurant and luxury boutique suites.

2611 Adams Ave, San Diego, CA 92116
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Bankers Hill Mixed-Use Opportunity
$2,849,000
3,800 SF

Bankers Hill Mixed-Use Opportunity

Three-story mixed-use building in Bankers Hill with flexible zoning.

2368 2nd Ave, San Diego, CA 92101
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Mixed-Use Redevelopment Opportunity
$1,688,888
0.15 Acres

Mixed-Use Redevelopment Opportunity

Mixed-use property with redevelopment potential near 3rd Avenue Promenade.

402 Church Ave, Chula Vista, CA 91910
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San Diego County, CA Mixed-Use Properties Investment Opportunities Market Analysis

Explore 51 mixed-use properties for sale in San Diego County, CA, showcased through 51 active listings on our real estate platform. These investment opportunities span a total of 1,421,321,386 square feet of properties for sale, with an estimated market value of $57,579,999.

Sale prices for multi use buildings in San Diego County, CA start at $220,000, averaging $3,030,526, and reaching up to $32,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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