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San Mateo County, CA Office Spaces for Sale

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Mixed-Use Duplex with Office Unit
Updated: Jun 6
Mixed-Use Duplex with Office Unit

5480 Mission ST, San Francisco, CA 94112

$999,000
2,500 sqft 0.05 AC lot
Mixed‑use duplex with residential unit plus an additional unit designed for office/boutique business/creative studio uses
Residential unit offers a 2‑bedroom, 2‑bath layout
Forced air central heating and public water
Composition roof
Built in 1924
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5480 Mission ST, SAN FRANCISCO, CA 94112

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Turnkey Office & Retail Building
Updated: Jun 26
Turnkey Office & Retail Building

1939 Divisadero Street, San Francisco, CA 94115

$3,500,000
7,179 sqft 0.07 AC lot
Built in 1923; converted from an original apartment building into professional office suites
24 individual office spaces plus 1 ground‑floor retail suite
Tenant roster primarily includes therapists and counseling professionals
Only three office vacancies; in‑place 6.5% capitalization rate reported
Flexible lease structure offers option for an owner‑user to occupy space while keeping income from existing tenants
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Mixed-Use Retail Showroom Property
Mixed-Use Retail Showroom Property

423 Valencia Street, San Francisco, CA 94103

$5,800,000
8,700 sqft 0.10 AC lot

Flexible building space with curbside parking along Valencia Corridor supports retail, showroom, creative office, and gallery concepts.

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Ground-Floor Commercial Condo
Ground-Floor Commercial Condo

5020 Mission Street Unit 1, San Francisco, CA 94112

$399,900
831 sqft 0.02 AC lot

Flexible ground-floor unit with open layout, set in an NC-3 zone and supported by established monthly HOA dues.

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Mixed-Use Commercial Property with Parking
Mixed-Use Commercial Property with Parking

423 Valencia Street, San Francisco, CA 94103

$5,800,000
8,700 sqft 0.23 AC lot

Flexible showroom, retail, and office space with curbside parking on a substantial lot in San Francisco’s Valencia Corridor.

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Mixed-Use Retail and Residential Building
Mixed-Use Retail and Residential Building

3774 Mission ST, San Francisco, CA 94110

$1,900,000
2,536 sqft 0.06 AC lot

Mixed-use building with a Mission Street storefront plus three renovated residential units delivered vacant for sale.

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Office Space
Office Space

617 7th ST, San Francisco, CA 94103

$350,000
0.02 AC lot

For-sale commercial suite zoned C3 in San Francisco’s Financial District.

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Two-Story Commercial Building
Two-Story Commercial Building

729 Bush Street, San Francisco, CA 94108

$2,795,000
5,072 sqft 0.09 AC lot

Two-story building with basement, located near Downtown transit and offered for sale in an RC-4 flexible-use zone.

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Corner Flex Office/Warehouse
Corner Flex Office/Warehouse

101 E 25th Ave, San Mateo, CA 94403

$2,800,000
3,850 sqft 0.26 AC lot

Renovated office and warehouse/storage with a detached restroom, shower, and lockers plus gated parking on a corner parcel.

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Fully Secured Biotech Lab Facility
Fully Secured Biotech Lab Facility

560 Eccles AVE, South San Francisco, CA 94080

$48,000,000
3.65 AC lot

2019-built lab and warehouse facility on 3.65 acres with secured access, dock-high loading, and backup power.

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Light Industrial Condominium with Roll-Up
Light Industrial Condominium with Roll-Up

San Francisco, CA 94124

$795,000
1,592 sqft

Turnkey unit with finished office, kitchenette, warehouse space, 16-foot ceilings, and a 10-foot roll-up door.

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Three-Unit Mixed-Use Building
Three-Unit Mixed-Use Building

1014 Clement Street, San Francisco, CA 94118

$2,100,000
5,964 sqft

Mixed-use building with ground-floor retail and office space on upper floors, including a partially vacant third floor.

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Redwood City Redevelopment Opportunity
Redwood City Redevelopment Opportunity

65 Winslow, Redwood City, CA 94063

$4,400,000
6,324 sqft 0.42 AC lot

Corner lot near downtown Redwood City primed for redevelopment.

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Corner Retail and Office Building
Corner Retail and Office Building

701 Laurel St, San Carlos, CA 94070

$7,000,000
14,000 sqft

Two-story building with ground-floor retail/office units and 19 second-floor offices on a corner site.

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Integrated Live/Work Creative Property
Integrated Live/Work Creative Property

266 14th Street, San Francisco, CA 94103

$4,500,000
10,102 sqft

Adaptable live/work property designed for functionality and creative expression.

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SoMa Mixed-Use Building Opportunity
SoMa Mixed-Use Building Opportunity

471 Jessie St, San Francisco, CA 94103

$1,740,000
4,650 sqft

Mixed-use building in SoMa, San Francisco, ideal for owner-user.

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Creative Office Building
Creative Office Building

948-950 Howard Street, San Francisco, CA 94107

$1,950,000
4,100 sqft

Fee-simple creative office space with mostly open collaboration layout, kitchenette, breakout rooms, and a conference room.

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Mixed-Use Retail and Office Building
Mixed-Use Retail and Office Building

726730 El Camino Real, Redwood City, CA 94063

$1,250,000
2,580 sqft

Ground-floor retail storefront with separate second-floor office suite, offering flexibility for an owner-user or investor.

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Prime Design District Opportunity
Prime Design District Opportunity

San Francisco, CA 94103

$2,900,000
4,800 sqft 0.15 AC lot

Commercial property with parking, warehouse, and office space for sale.

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Cold Shell Office Suite
Cold Shell Office Suite

101a-600 El Camino Real, Belmont, CA 94002

$3,000,000
3,057 sqft

Cold shell office suite with dedicated parking and flexible space for professional or healthcare use in a mixed-use setting.

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Warehouse with Office
Warehouse with Office

330 Hatch Drive, Foster City, CA 94404

$7,850,000
17,875 sqft

Warehouse with grade-level loading and integrated office space, supported by 19’ clear height and multiple power disconnects.

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Versatile Flex Space Available
Versatile Flex Space Available

Menlo Park, CA 94025

$8,000,000
2,400 sqft

Adaptable flex space suitable for various commercial uses.

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Creative Live/Work Loft Building
Creative Live/Work Loft Building

1066 Bryant Street, San Francisco, CA 94103

$2,998,000
6,600 sqft 0.06 AC lot

Vacant live/work building with city views and creative potential.

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Downtown San Francisco Mixed-Use Building
Downtown San Francisco Mixed-Use Building

34-38 Mason St, San Francisco, CA 94102

$5,250,000
12,375 sqft

12,375 sqft mixed-use building in prime downtown location.

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San Mateo County, CA Office Spaces Market Trends and Statistics

Explore 183 office spaces for sale in San Mateo County, CA, showcased through 183 active listings on our real estate platform. These investment opportunities span a total of 975,867 square feet of properties for sale, with an estimated market value of $493,680,676.

Sale prices for office spaces in San Mateo County, CA start at $333,000, averaging $4,114,005, and reaching up to $48,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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