Hilton Head Island, SC Mixed-use properties for sale

Updated: Nov 21, 2025

Mixed-Use Commercial Building

127 Mathews Dr, Hilton Head Island, SC 29926

Contact for pricing

3,100 sqft

3,100 SF mixed‑use building
Light Commercial zoning
Constructed in 1966
Potential uses include multifamily, educational, restaurant, and office applications
Redevelopment options include car wash, grocery, and self‑storage uses

View details

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 1 Active listings in Hilton Head Island, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 2 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Updated Mixed-Use Property

217 Goethe Road, Bluffton, SC 29910

$1,749,900

Two commercial buildings provide office, retail, and flex configurations with existing tenant occupancy.

View details

Prime Corner Lot in Port Royal

1008 Paris Avenue, Port Royal, SC 29935

$950,000

0.23 AC lot

0.23-acre mixed-use parcel in vibrant Port Royal's T4-Urban Center.

View details

Renovated Mixed-Use Property

1503 Paris Avenue, Port Royal, SC 29935

$739,777

0.12 AC lot

MU1 zoning supports residential, commercial, and combined mixed-use occupancy.

View details

Mixed-Use Development Lot

25 Maiden Lane, Bluffton, SC 29910

$450,000

Create a business with living space near Bluffton’s dining, shopping, waterways, and boat access.

View details

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

General Mixed-Use Commercial Land

42 Plantation Park Drive, Bluffton, SC 29910

$1,099,000

Mostly cleared site with existing master stormwater detention and no wetlands.

View details

Waterfront Commercial Land

110 Windrush Lane, Bluffton, SC 29910

$50,000

1.73 AC lot

Mixed-use zoning accompanies uplands, wetlands, a pond, and lagoon waterfront features.

View details

Commercial Land with Restaurant Approval

1750 Ribaut Road, Port Royal, SC 29935

$825,000

0.87 AC lot

Commercial development site with approved restaurant plans, public water, and public sewer service.

View details

Beaufort Commercial Land For Sale

2619 Holmes Drive, Beaufort, SC 29902

$35,000

0.56 AC lot

Land approved for 12 condominiums in Beaufort, South Carolina.

View details

Off-Market Properties in Hilton Head Island, SC

Consider similar Off-Market properties in Hilton Head Island, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

OFFICE/RESIDENTIAL (MIXED USE)

6 Executive Park Rd, Hilton Head Island, SC 29928-4741

$350,000

Estimated value

3,240 sqft 0.30 AC lot

View details

Residential offices

5 Dunmore Court Hilton, Head Island, SC 29926

$2,200,000

Estimated value

View details

Hilton Head Island, SC Mixed-use Properties for Sale

127 Mathews Dr, Hilton Head Island, SC 29926