Lake County, FL Medical Office Space for Rent & Lease

Updated: Feb 25

Leesburg Office Space Available

401 E NORTH BOULEVARD, Leesburg, FL 34748

$3,000/Mo

9,800 sqft

Prime location near downtown Leesburg and the hospital, with easy access via 441 frontage.
Ample parking available for over 60 vehicles.
Two 2000 sq ft units available, connectable for a total of 4000 sq ft.
Existing layout includes reception areas, exam rooms, and waiting rooms, suitable for various businesses.
Monthly rent includes CAM and taxes.

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Updated: Oct 6, 2025

Medical Office Building with Surgery Room

640 S LAKE STREET, Leesburg, FL 34748

$26/Mo

8,642 sqft

4,072 SF medical office for lease directly across from UF Health Leesburg Hospital
9 exam rooms plus multiple private offices, ample storage, and a dedicated surgery room
Separate private waiting room for the surgery room and a spacious waiting and reception area
Zoned C‑2; block construction and central air
Roof replaced about 3 years ago

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Medical Office Near UF Health

640 S LAKE St, Leesburg, FL 34748

$105,872 SF/Yr

4,072 sqft

4,072 SF medical office space for lease.

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Medical Office Suite with Exam Rooms

A-841 Oakley Seaver Dr, Clermont, FL 34711

$45,000 SF/Yr

1,494 sqft

Medical office suite with three exam rooms, patient and staff washrooms, and wired IT space for straightforward move-in.

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Single-Story Outpatient Medical Facility

305 County Road 466A, Fruitland Park, FL 34731

Contact for pricing

2,189 sqft

Purpose-built outpatient healthcare space with 14-foot clear height and signage facing Miller Blvd.

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Medical Office Building with Monument Signage

600 W North Blvd, Leesburg, FL 34788

Contact for pricing

11,234 sqft

Recently renovated ground-floor medical suites with covered drop-off and signage for easy patient access.

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Inviting Retail/Medical Space in Eustis

2 N Eustis St # 18, Eustis, FL 32726

Contact for pricing

1,756 sqft

Versatile retail/medical space in a prime Eustis location.

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Medical Office Near Southlake Hospital

841 OAKLEY SEAVER Dr A, Clermont, FL 34711

$45,000 SF/Yr

Move-in ready medical office space with no CAM fees.

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Move-In Ready Clermont Medical Office

805 Oakley Seaver Dr, Clermont, FL 34711

Contact for pricing

2,988 sqft

Move-in ready medical office space in South Lake Medical Arts Center.

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Prime New Construction Office Space

17215 Grassy Lake Rd, Minneola, FL 34715

$45 SF/Yr

11,039 sqft

New medical and professional office space for lease in Minneola.

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Turn-Key Medical Office Building

1414 E MAIN STREET, Leesburg, FL 34748

$135,198 SF/Yr

7,511 sqft

Medical office building near UF Health Hospital in Leesburg.

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Medical Retail Space Available

3711 S US 27, Clermont, FL 34711

$20 SF/Yr

Medical retail space in Clermont, close to healthcare providers.

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Prime Commercial Office Space Available

3360 US HIGHWAY 441/27, Fruitland Park, FL 34731

$30,000 SF/Yr

Highly visible office space for lease with flexible options.

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Mixed-Use Commercial Space Available

County Rd 561, Minneola, FL

Contact for pricing

165,000 sqft

Ground floor commercial space in mixed-use development for rent.

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Leesburg Medical Park Office Space

704 DOCTORS COURT, Leesburg, FL 34748

$14,112/Mo

1,008 sqft

Medical office space for lease near UF Health Leesburg.

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Medical Office Space Available

33041 PROFESSIONAL DRIVE, Leesburg, FL 34788

$36,720 SF/Yr

2,040 sqft

Nicely finished medical office space, convenient location, available for lease.

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Medical Office Suites For Lease

301 Frontage Rd, Clermont, FL

$3,000/Mo

1,664 sqft

Newly renovated medical office suites available for lease in Clermont.

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Retail/Medical Space on Highway 441

1450 E N Blvd, Leesburg, FL

Contact for pricing

3,375 sqft

Retail or medical spaces available on a high-traffic corridor.

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Based on your search, we've compiled 42 Potential Opportunities for your consideration. Besides 18 Active listings in Lake County, FL, we suggest exploring alternatives. Similar 24 Properties for Sales.

Similar Spaces for Sale in Lake County, FL

Consider Similar Space for Sale. We found 24 Spaces matching your search parameters.

Leesburg Office Building on Highway 441

401 E NORTH BOULEVARD, Leesburg, FL 34748

$1,250,000

9,800 sqft 1.13 AC lot

9,800 SF medical/professional office building with highway frontage.

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Veterinary Hospital Investment Opportunity

3300 N HIGHWAY 19A, Mount Dora, FL 32757

$2,100,000

7,159 sqft 0.89 AC lot

Corporate-backed veterinary hospital with long-term NNN lease in place.

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Tavares Commercial Opportunity

915 E ALFRED STREET, Tavares, FL 32778

$1,300,000

5,124 sqft 1.25 AC lot

Two office buildings with development potential in Tavares, Florida.

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Versatile Office Space in Eustis

600 N EUSTIS STREET, Eustis, FL 32726

$375,000

3,021 sqft 0.39 AC lot

Office space with private parking near downtown Eustis, Florida.

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Leesburg Mixed-Use Commercial Property

711 N 3RD ST, Leesburg, FL 34748

$1,600,000

15,300 sqft 0.87 AC lot

Turnkey investment opportunity with medical suites and self-storage units.

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Medical/Professional Office Space on 441

401 E NORTH Blvd, Leesburg, FL 34748

$1,250,000

9,800 sqft

9,800 SF medical/professional office space with highway frontage.

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Lake County, FL Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Lake County, FL with 18 listings featured on our commercial real estate exchange. The current inventory includes 47,270 square feet of properties with an estimated lease value of $323,054.

Estimated lease rates for Medical Office Space in Lake County, FL begin at $3.67 SF/Yr, with an average of $35,894 and extend to $135,198.