Lake County, FL Medical Office Space for Rent & Lease

$3,000/Mo

9,800 SF

Leesburg Office Space Available

401 E NORTH BOULEVARD, Leesburg, FL 34748

Two office units available, suitable for various businesses.

Prime location near downtown Leesburg and the hospital, with easy access via 441 frontage.
Ample parking available for over 60 vehicles.
Two 2000 sq ft units available, connectable for a total of 4000 sq ft.
Existing layout includes reception areas, exam rooms, and waiting rooms, suitable for various businesses.
Monthly rent includes CAM and taxes.

Updated: Feb 25

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Medical Office Building with Surgery Room

$26 SF/Yr

8,642 SF

Medical Office Building with Surgery Room

640 S LAKE STREET, Leesburg, FL 34748

Well-maintained medical office offers 9 exam rooms and abundant parking directly across from UF Health Leesburg Hospital.

4,072 SF medical office for lease directly across from UF Health Leesburg Hospital
9 exam rooms plus multiple private offices, ample storage, and a dedicated surgery room
Separate private waiting room for the surgery room and a spacious waiting and reception area
Zoned C‑2; block construction and central air
Roof replaced about 3 years ago

Updated: Oct 6, 2025

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Medical/Professional Office Space Available

$57,200 SF/Yr

2,200 SF

Medical/Professional Office Space Available

2200 SF medical/professional office space for rent, move-in ready.

235 HATTERAS Ave 100, Clermont, FL 34711

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Medical/Professional Office Park Anchor Building

$25 SF/Yr

21,000 SF

Medical/Professional Office Park Anchor Building

Prominent medical/professional office building with high-end finishes and signage.

2757 Citrus Tower Blvd, Clermont, FL 34711

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1,756 SF

Inviting Retail/Medical Space in Eustis

Versatile retail/medical space in a prime Eustis location.

2 N Eustis St # 18, Eustis, FL 32726

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2,988 SF

Move-In Ready Clermont Medical Office

Move-in ready medical office space in South Lake Medical Arts Center.

805 Oakley Seaver Dr, Clermont, FL 34711

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$45,000 SF/Yr

Medical Office Near Southlake Hospital

Move-in ready medical office space with no CAM fees.

841 OAKLEY SEAVER Dr A, Clermont, FL 34711

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$20 SF/Yr

Medical Retail Space Available

Medical retail space in Clermont, close to healthcare providers.

3711 S US 27, Clermont, FL 34711

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Medical Office Building with Monument Signage

Contact for pricing

11,234 SF

Medical Office Building with Monument Signage

Recently renovated ground-floor medical suites with covered drop-off and signage for easy patient access.

600 W North Blvd, Leesburg, FL 34788

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$30,000 SF/Yr

Prime Commercial Office Space Available

Highly visible office space for lease with flexible options.

3360 US HIGHWAY 441/27, Fruitland Park, FL 34731

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$135,198 SF/Yr

7,511 SF

Turn-Key Medical Office Building

Medical office building near UF Health Hospital in Leesburg.

1414 E MAIN STREET, Leesburg, FL 34748

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5,396 SF

Medical Office Space Available

Move-in ready, renovated medical suites with ample parking.

600 W North Blvd, Leesburg, FL

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11,039 SF

Prime New Construction Office Space

New medical and professional office space for lease in Minneola.

17215 Grassy Lake Rd, Minneola, FL 34715

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$3,000/Mo

1,664 SF

Medical Office Suites For Lease

Newly renovated medical office suites available for lease in Clermont.

301 Frontage Rd, Clermont, FL

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3,375 SF

Retail/Medical Space on Highway 441

Retail or medical spaces available on a high-traffic corridor.

1450 E N Blvd, Leesburg, FL

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165,000 SF

Mixed-Use Commercial Space Available

Ground floor commercial space in mixed-use development for rent.

County Rd 561, Minneola, FL

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4,003 SF

Retail Space in Publix Outparcel

2,212 SF gray shell space ideal for various uses.

24430 State Road 44, Sorrento, FL 32776

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6,183 SF

Highway Frontage Retail/Office Space

Retail and office spaces available on a high-traffic highway.

Mount Dora, FL 32757

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Based on your search, we've compiled 49 Potential Opportunities for your consideration. Besides 18 Active listings in Lake County, FL, we suggest exploring alternatives. Similar 31 Properties for Sales.

Similar Spaces for Sale in Lake County, FL

Consider Similar Space for Sale. We found 31 Spaces matching your search parameters.

$1,250,000

9,800 SF

Leesburg Office Building on Highway 441

9,800 SF medical/professional office building with highway frontage.

401 E NORTH BOULEVARD, Leesburg, FL 34748

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$375,000

3,021 SF

Versatile Office Space in Eustis

Office space with private parking near downtown Eustis, Florida.

600 N EUSTIS STREET, Eustis, FL 32726

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Eustis Office Near AdventHealth Waterman

$500,000

1,950 SF

Eustis Office Near AdventHealth Waterman

Professional or medical office space in a convenient Eustis location.

1318 S EUSTIS STREET, Eustis, FL 32726

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Veterinary Hospital Investment Opportunity

$2,100,000

7,159 SF

Veterinary Hospital Investment Opportunity

Corporate-backed veterinary hospital with long-term NNN lease in place.

3300 N HIGHWAY 19A, Mount Dora, FL 32757

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$700,000

12,588 SF

Mixed-Use Property in Fruitland Park

Commercial properties with high visibility in a growing Central Florida corridor.

300 N DIXIE AVENUE, Fruitland Park, FL 34731

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$1,300,000

5,124 SF

Tavares Commercial Opportunity

Two office buildings with development potential in Tavares, Florida.

915 E ALFRED STREET, Tavares, FL 32778

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Lake County, FL Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Lake County, FL with 18 listings featured on our commercial real estate exchange. The current inventory includes 44,314 square feet of properties with an estimated lease value of $57,459.

Estimated lease rates for Medical Office Space in Lake County, FL begin at $3 SF/Yr, with an average of $9,576 /Mo and extend to $57,200.

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