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Seneca, SC Commercial Real Estate for Sale

101 results
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Seneca Commercial Buildings For Sale
$450,000
1.02 Acres

Seneca Commercial Buildings For Sale

306 Byp Unit Building B And,Unit C, Seneca, SC 29678

Two industrial buildings with flexible space and manufacturing potential.

  • Two buildings included: Building B (4650 SF) with office space and Building C (5000 SF) with an open floor plan
  • Ample level parking available
  • Utilities in place: Seneca Light, Water, Sewer, and Garbage services
  • Multiple power options available: 120 volt 1 phase, 220 volt 3 phase, and 480 volt 3 phase
  • Each building has two roll‑up doors and a walk‑in door
Last Update: Sep 25
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Seneca Commercial Property with Expansion Potential
$687,500
3.95 Acres

Seneca Commercial Property with Expansion Potential

298 Worth St, Seneca, SC 29678

High-visibility commercial property ideal for storage, sales, or service center.

  • Prime Location: Direct access and high visibility on By‑Pass 123, a major traffic corridor.
  • Large Scale Facility: Over 21,000 sq ft under roof on nearly 4 acres, designed to accommodate large vehicles.
  • Expansion Potential: Includes adjacent parcel on Worth Street.
  • Engineer‑Approved Building: Structure reviewed and approved.
  • Tax Credit Eligibility: Qualifies for South Carolina's Abandoned Buildings Tax Credit program, potentially offering significant savings up to $700K.
Last Update: Sep 22
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Studio Condo Near Clemson Campus
$270,000

Studio Condo Near Clemson Campus

Studio condo near Clemson University with rental management options.
13500 Clemson Blvd, Seneca, SC 29678
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Affordable Townhome Near Clemson University
$152,500

Affordable Townhome Near Clemson University

Townhome near Clemson University, ideal for rental or affordable living.
1034 Ridgeview Ln, Seneca, SC 29678
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Seneca Office Building - High Traffic Area
$250,000
0.78 Acres

Seneca Office Building - High Traffic Area

Prime Seneca location, high visibility, multiple uses.
108 Keowee School Rd, Seneca, SC 29672
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Seneca Commercial Land - 33.9 Acres
$1,577,000
33.90 Acres

Seneca Commercial Land - 33.9 Acres

Prime Seneca acreage, development potential.
Unit 31.66 ac 31.54 Acres Frontage Rd, Seneca, SC 29678
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Seneca Office Building For Sale
$499,950
0.15 Acres

Seneca Office Building For Sale

Modern Office Space, Turn-Key Ready
8 Accountants Cir, Seneca, SC 29678
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Seneca Commercial Land Opportunity
$325,000
8.04 Acres

Seneca Commercial Land Opportunity

8 Acres, Highway Frontage, Three Parcels
000000 Wells Hwy, Seneca, SC 29678
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Seneca Commercial Land - 1.8 Acres
$790,000
1.80 Acres

Seneca Commercial Land - 1.8 Acres

High-traffic location, unrestricted, near major retailers.
1.8 Acres Rochester Hwy, Seneca, SC 29672
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Downtown Seneca Office Space
Contact for pricing
0.11 Acres

Downtown Seneca Office Space

Prime Seneca location, flexible office suites.
108 North 1St St, Seneca, SC 29678
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Seneca Industrial Building - Great Location!
$349,900
0.50 Acres

Seneca Industrial Building - Great Location!

Versatile 4218 sq ft building, ideal for retail or light industrial use.
310 North 2Nd St, Seneca, SC 29678
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Seneca Commercial Land - 77 Acres
$3,833,000
78.90 Acres

Seneca Commercial Land - 77 Acres

Prime Seneca acreage, city limits, development potential.
Unit Keowee I 76.66 Acres Frontage Rd And Knollwood Dr Rd, Seneca, SC 29678
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Seneca Commercial Land - Highway 123
$1,050,000
1.45 Acres

Seneca Commercial Land - Highway 123

High-traffic location, build-to-suit option available.
994 Us 123 Hwy, Seneca, SC 29678
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Seneca Commercial Land - Prime Location
$325,000
1.29 Acres

Seneca Commercial Land - Prime Location

1.29 Acres, High Visibility, Zoned GC
911 North 1St St, Seneca, SC 29678
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Historic Seneca Mill Property
$169,000
1.30 Acres

Historic Seneca Mill Property

Prime 1.3-acre Mill Site, Seneca, SC
00 Hwy 24 Hwy, Seneca, SC 29678
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Lake Keowee Commercial Land
$2,250,000
45.00 Acres

Lake Keowee Commercial Land

45 Acres, Seneca, SC - Investment Opportunity
Unit Keowee I 45+/- Acres Knollwood Dr, Seneca, SC 29678
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Seneca Medical Office Building
$2,283,233
6,227 SF

Seneca Medical Office Building

High-yield, single-tenant medical office
10110 Clemson Blvd, Seneca, SC 29672
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Luxury Condo Hotel Near Campus
$292,110

Luxury Condo Hotel Near Campus

Studio condo in luxury hotel with rental management options.
13500 Clemson Blvd, Seneca, SC 29678
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Medical Office NNN Investment
$2,283,233
6,227 SF

Medical Office NNN Investment

Single tenant medical office building with long-term lease.
10110 Clemson Blvd, Seneca, SC 29672
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Retail Property on Main Corridor
$1,000,000
7,250 SF

Retail Property on Main Corridor

Retail property with excellent visibility and heavy traffic.
1592 Sandifer Blvd, Seneca, SC 29678
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Two Warehouses Near Clemson
$490,000
9,650 SF

Two Warehouses Near Clemson

Two warehouse buildings totaling 9,650 SF on one acre.
306 By Pass 123, Seneca, SC 29678
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Seneca Office Space For Sale
$599,000
2,400 SF

Seneca Office Space For Sale

Office space conveniently located off Bypass 123 in Seneca, SC.
631 By Pass 123, Seneca, SC 29678
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Explore Off-Market Properties in Seneca, SC

Consider similar Off-Market properties in Seneca, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

108 North 1St St

108 North 1St St

Office Properties & Spaces • 0.11 Acres
Value Estimation by Request
108 North 1St St, Seneca, SC 29678
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1.8 Acres Rochester Hwy

1.8 Acres Rochester Hwy

Commercial real estate • 1.80 Acres
Value Estimation by Request
1.8 Acres Rochester Hwy, Seneca, SC 29672
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Seneca, SC Commercial Real Estate Investment Opportunities Market Analysis

Explore 1070 commercial real estate investment opportunities in Seneca, SC with 101 listings featured on our commercial real estate marketplace. The current inventory includes 70,452,492 square feet of properties with an estimated value of $281,217,418.

Estimated prices for commercial real estate in Seneca, SC begin at $38,500, with an average of $904,236 and extend to $24,940,000.

In Seneca, SC, current investment values show:

  • Retail properties positioned at $725,468
  • Land measuring $675,948
  • Individual retail properties assessed at $535,666
  • Office Properties & Spaces calculated at $1,520,174
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