Lancaster, SC Office buildings for sale

Updated: Dec 1, 2025

Medical Office Building with Two Suites

1201 Colonial Commons Court, Lancaster, SC 29720

$975,000

0.82 AC lot

Building 1 has new flooring and a new roof
PO zoning per the City of Lancaster
Medical setup includes an x‑ray room that is wired in Building 1
Building 1 offers about 14 rooms plus reception and waiting
Building 2 has three curtained areas, reception/waiting, and upper‑level work stations

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Updated: Jun 11

Historic Mixed-Use Retail/Office Buildings

209-227 S. Main Street, Lancaster, SC 29720

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29,151 sqft

1930s‑vintage commercial buildings in downtown Lancaster, SC, historically used for retail or office space
Currently vacant and in need of renovation—space offers a value‑add rehabilitation opportunity
Off Highway 521 and about 5 minutes from the Highway 9 intersection
Within 10 miles: population of over 56,000 grew 10% since 2020, with a forecast to grow an additional 16% by 2029
More than $641 million in consumer spending during 2024 within 10 miles

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Downtown Mixed-Use Building for Renovation

229 S. Main Street, Lancaster, SC 29720

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15,266 sqft

Vacant 1930s mixed-use property in downtown Lancaster, built for retail or office re-activation with renovation underway.

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Downtown Mixed-Use Redevelopment Property

210 S. White Street, Lancaster, SC 29720

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22,251 sqft

Vacant 1930s retail/office buildings in downtown Lancaster offer a renovation-ready canvas for mixed-use redevelopment.

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1930s Retail/Office Building Portfolio

116 Arch Street, Lancaster, SC 29720

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29,444 sqft

Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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Office Building

312 N Main Street N, Lancaster, SC 29720

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2,706 sqft

Office building with some furnishings staying, and utility split where tenant pays electricity and natural gas.

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Office Building with Live-Work Use

36-305 E Arch St, Lancaster, SC 29720

$250,000

B-2 zoning supports residential occupancy alongside a business, with parking and accessible entry.

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Versatile Commercial Building in Lancaster

302 N White St, Lancaster, SC 29720

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Two-story commercial building with offices in downtown Lancaster, SC.

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Based on your search, we've compiled 16 Potential Opportunities for your consideration. Besides 8 Active listings in Lancaster, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

General Commercial Development Site

1195 Albright Rd, Rock Hill, SC 29730

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7,300 sqft 3.44 AC lot

Commercial land zoned GC with conceptual plans for a future building and proposed access via easement.

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Manufacturing Building with Office Space

463 Lakeshore Pkwy, Rock Hill, SC 29730

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33,934 sqft 4.00 AC lot

PUD-zoned manufacturing building with dedicated office space and multiple loading doors for flexible operations.

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Office Building For Sale

1125 Skyway Dr, Monroe, NC 28110

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32,499 sqft

Office building offered for sale with a stated 7.96% capitalization rate.

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Office Building For Sale

300 N Hayne St, Monroe, NC 28110

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Office building offered for sale at 300 N Hayne St.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Brick Office Units

2836 Lynwood Drive, Lancaster, SC 29720

$149,900

0.47 AC lot

Brick construction with carpeted flooring, electric heat, and central air conditioning.

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Rock Hill Commercial Land Available

2164 Eden Terrace, Rock Hill, SC 29730

$350,000

3.64 AC lot

3.64 acre commercial land parcel in Rock Hill, SC.

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Commercial Lot in Rock Hill

2135 Eden Terrace, Rock Hill, SC 29730

$450,000

1.08 AC lot

Commercial land for sale, suitable for development or owner financing.

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Medical Office Park Land

Charles Hunley Lane, Monroe, NC 28112

$1,700,000

7.62 AC lot

Commercial acreage positioned for medical or office development near established healthcare and business services.

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Lancaster, SC Office Buildings Market Trends and Statistics

Explore 8 office buildings for sale in Lancaster, SC, showcased through 8 active listings on our real estate platform. These investment opportunities span a total of 98,818 square feet of properties for sale, with an estimated market value of $1,225,000.

Sale prices for office properties in Lancaster, SC start at $250,000, averaging $612,500, and reaching up to $975,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Neighborhood	Average Price
29720	$487.5K

Neighborhood

Average Price

29720

$487.5K