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    Lancaster, SC Office Buildings for Sale

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    Heath Springs, SC Van Wyck, SC Fort Lawn, SC Waxhaw, NC Catawba, SC Richburg, SC Edgemoor, SC Great Falls, SC
    9 properties
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    Commercial Land with Office Building
    Updated: Sep 8
    Commercial Land with Office Building

    731 S Market Street, Lancaster, SC 29720

    $140,000
    1.62 AC lot
    1.62‑acre commercial parcel
    B3 General Business zoning
    Existing office building positioned along the edge of the lot
    Approximately 270 feet of frontage on S Market Street
    Public water and sewer on site
    View details
    Two-Building Medical Office Property
    Updated: Dec 1, 2025
    Two-Building Medical Office Property

    1201 Colonial Commons Court, Lancaster, SC 29720

    $975,000
    0.82 AC lot
    Two professional buildings on a 0.82‑acre property
    Building 1 includes approximately 14 rooms, reception, waiting, and file areas
    Building 1 has new flooring and a new roof
    Building 2 features three curtained areas and a large open space
    PO Professional Office zoning per the City of Lancaster
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    Historic Mixed-Use Retail/Office Buildings
    Historic Mixed-Use Retail/Office Buildings

    209-227 S. Main Street, Lancaster, SC 29720

    Contact for pricing
    29,151 sqft

    Vacant 1930s buildings offer retail or office space and renovation opportunity in downtown Lancaster, South Carolina.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Downtown Mixed-Use Redevelopment Property
    Downtown Mixed-Use Redevelopment Property

    210 S. White Street, Lancaster, SC 29720

    Contact for pricing
    22,251 sqft

    Vacant 1930s retail/office buildings in downtown Lancaster offer a renovation-ready canvas for mixed-use redevelopment.

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    1930s Retail/Office Building Portfolio
    1930s Retail/Office Building Portfolio

    116 Arch Street, Lancaster, SC 29720

    Contact for pricing
    29,444 sqft

    Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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    Office Building
    Office Building

    312 N Main Street N, Lancaster, SC 29720

    Contact for pricing
    2,706 sqft

    Office building with some furnishings staying, and utility split where tenant pays electricity and natural gas.

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    Versatile Commercial Building in Lancaster
    Versatile Commercial Building in Lancaster

    302 N White St, Lancaster, SC 29720

    $325,000

    Two-story commercial building with offices in downtown Lancaster, SC.

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    Office Building with Live-Work Use
    Office Building with Live-Work Use

    36-305 E Arch St, Lancaster, SC 29720

    $250,000

    B-2 zoning supports residential occupancy alongside a business, with parking and accessible entry.

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    Commercial Land with Office Building
    Commercial Land with Office Building

    731 S Market St, Lancaster, SC 29720

    $140,000

    B3-zoned parcel with an existing office building and city utilities on site.

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    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 9 Active listings in Lancaster, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Freestanding Office Building
    Freestanding Office Building

    500 Lakeshore Parkway, Rock Hill, SC 29730

    Contact for pricing
    6,560 sqft 1.18 AC lot

    Single-story layout includes private offices, reception areas, conference space, workstations, and on-site parking.

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    Renovated Stand-Alone Office Building
    Renovated Stand-Alone Office Building

    120 E Phifer St, Monroe, NC 28110

    Contact for pricing
    3,000 sqft 0.40 AC lot

    OM-zoned office property with modern renovations and convenient access to major regional routes.

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    Monroe Office/Medical Building For Sale
    Monroe Office/Medical Building For Sale

    315 S Sutherland Ave, Monroe, NC

    Contact for pricing
    0.36 AC lot

    Two-story office/medical building in Monroe's medical and professional district.

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    Freestanding Medical Office Space
    Freestanding Medical Office Space

    611 E Main Street, Rock Hill, SC 29730

    $200,000

    Existing configuration includes a reception area, multiple offices, and a kitchen.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Brick Storefront Property
    Brick Storefront Property

    2836 Lynwood Drive, Lancaster, SC 29720

    $149,900
    0.47 AC lot

    Commercial space with central air, electric heat, carpet flooring, and a bathroom.

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    Commercial Land with Dual Frontage
    Commercial Land with Dual Frontage

    2164 Eden Terrace, Rock Hill, SC 29730

    $350,000
    3.64 AC lot

    GC-zoned development site with public sewer and access from two road frontages.

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    O-I Zoned Commercial Land
    O-I Zoned Commercial Land

    2135 Eden Terrace, Rock Hill, SC 29730

    $450,000
    1.08 AC lot

    The parcel is zoned O-I and has public sewer service for commercial land planning.

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    Medical Office Development Land
    Medical Office Development Land

    Charles Hunley Lane, Monroe, NC 28112

    $1,700,000
    7.62 AC lot

    Commercial land within a medical and office park, positioned near major highways, healthcare services, restaurants, and businesses.

    View details

    Lancaster, SC Office Buildings Market Trends and Statistics

    Explore 9 office buildings for sale in Lancaster, SC, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 83,552 square feet of properties for sale, with an estimated market value of $1,830,000.

    Sale prices for office properties in Lancaster, SC start at $140,000, averaging $366,000, and reaching up to $975,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office buildings 9
    Medical Office Space 2
    Office Units 2

    Demographics Overview

    Population 52K
    Population Growth (5Y) +8.0%
    Median Household Income $59,039
    College Educated 9.5%

    High-Yield Neighborhoods for Investment

    Identify Lancaster submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29720 $387.5K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Lancaster County

    New Delisted

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