Seminole County, FL Commercial Real Estate for Sale

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330 properties
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Freestanding Medical Office
Updated: Aug 31
Freestanding Medical Office

2105 S PARK Avenue, Sanford, FL 32771

$549,000
1,550 sqft 0.28 AC lot
1,550‑square‑foot freestanding medical office
0.28‑acre property at 2105 S PARK Avenue, Sanford, FL 32771
Private parking lot and fenced yard
PD zoning
Central air with stone and stucco construction
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Freestanding Medical Office
Updated: Sep 15
Freestanding Medical Office

2711 W STATE ROAD 434, Longwood, FL 32779

$850,000
3,230 sqft 0.36 AC lot
3,230‑square‑foot freestanding medical office
Existing medical buildout with waiting area, reception, and private exam rooms
Open training room and 2 restrooms
Almost 100 feet of frontage along SR‑434
Over 40,000 Annual Average Daily Traffic through the area
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Two-Story Live-Work Building
Two-Story Live-Work Building

1150 N RONALD REAGAN Boulevard, Longwood, FL 32750

$725,000
2,480 sqft 0.31 AC lot

Renovated standalone property combines business space with residential-style accommodations and separate second-floor access.

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Mixed-Use Building with Private Offices
Mixed-Use Building with Private Offices

121 E 1st St Unit 101, Sanford, FL 32771

$1,500,000
7,987 sqft

A two-level configuration combines adaptable ground-floor space with a dedicated professional office layout upstairs.

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Warehouse Property With Industrial Land
Warehouse Property With Industrial Land

1101 ALBRIGHT Road, Sanford, FL 32771

$6,950,000
13,675 sqft 5.09 AC lot

Metal-frame warehouse improvements on an industrially zoned site with office space and access to major Central Florida routes.

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Freestanding Office Building
Freestanding Office Building

221 W STATE ROAD 434, Longwood, FL 32750

$1,350,000
4,549 sqft 0.63 AC lot

Flexible professional space with private offices, open work areas, support rooms, and prominent building signage.

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Modern Office Building with Generator
Modern Office Building with Generator

741 CIARA CREEK Cove, Longwood, FL 32750

$1,750,000
6,834 sqft 0.16 AC lot

Under-construction office property with private offices, open work areas, storage, and C-2 zoning for office and medical uses.

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Freestanding Flex Space Building
Freestanding Flex Space Building

221 W State Road 434, Longwood, FL 32750

$1,350,000
4,549 sqft 0.63 AC lot

Versatile commercial facility with private offices, open work areas, bathrooms, a kitchen, and flexible interior space.

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Five-Unit Mixed-Use Property
Five-Unit Mixed-Use Property

585 S RONALD REAGAN Boulevard, Longwood, FL 32750

$2,750,000
13,800 sqft 1.62 AC lot

Three units are vacant and available for lease, while two currently have tenants.

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Two-Building Office Property
Two-Building Office Property

180 S RONALD REAGAN Boulevard, Longwood, FL 32750

$799,999
3,202 sqft 0.23 AC lot

General Commercial zoning supports multiple office configurations across two freestanding buildings with separate entrances.

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Mixed-Use Commercial Complex
Mixed-Use Commercial Complex

2516 Sanford Ave, Sanford, FL 32773

$825,000
4,493 sqft 0.71 AC lot

Three-building property combines restaurant, live/work, and flex-space components.

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Auto Shop with Office Space
Auto Shop with Office Space

377 E STATE ROAD 434, Longwood, FL 32750

$650,000
1,002 sqft 0.62 AC lot

Transferable auto sales and repair licenses accompany this commercial property.

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Three-Building Mixed-Use Property
Three-Building Mixed-Use Property

2516 SANFORD Avenue, Sanford, FL 32773

$825,000
4,493 sqft 0.71 AC lot

Three-building commercial property with restaurant, apartment, and adaptable flex space under GC2 zoning.

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Office Building with Six Suites
Office Building with Six Suites

131 S Country Club Rd, Lake Mary, FL 32746

$3,880,000
10,592 sqft 1.10 AC lot

NNN-leased office property with flexible multi-tenant configuration, modern finishes, elevator access, and EV charging stations.

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Updated Office Building
Updated Office Building

657 MAITLAND Avenue, Altamonte Springs, FL 32701

$485,000
1,518 sqft 0.27 AC lot

A multi-room layout includes reception, conference, kitchen, flex space, restrooms, and dedicated parking.

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Freestanding Brewery Building
Freestanding Brewery Building

417 & 419 SANFORD Avenue, Sanford, FL 32771

$889,000
2,152 sqft 0.21 AC lot

Connected commercial suites offer a full kitchen, outdoor dining, and sidewalk cafe seating near Sanford’s waterfront district.

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Freestanding Flex Office Building
Freestanding Flex Office Building

1665 EE Williamson Road, Longwood, FL 32779

$1,899,999
9,648 sqft 1.67 AC lot

Freestanding building with flexible interior layout and ample parking, well-suited for office, school, daycare, or religious use.

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Combined Medical Office Suite
Combined Medical Office Suite

7560 RED BUG LAKE RD, Oviedo, FL 32765

$1,850,000
4,690 sqft 0.03 AC lot

Second-floor medical office with elevator access, specialized clinical rooms, furnishings, and equipment in place.

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Renovated Flex Space
Renovated Flex Space

541 N US HIGHWAY 17 92, Longwood, FL 32750

$1,999,900
7,100 sqft

Updated interiors and a refreshed exterior accommodate a mix of commercial occupants.

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Furnished Office Building
Furnished Office Building

78 S WINTER PARK Drive, Casselberry, FL 32707

$440,000
2,166 sqft 0.30 AC lot

A renovated, furnished interior includes four bedrooms, three bathrooms, and an updated kitchen.

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Shopping Center with Diverse Tenant Mix
Shopping Center with Diverse Tenant Mix

1007 W State Rd 434, Winter Springs, FL 32708

$2,300,000
8,729 sqft

Multi-tenant plaza combines retail, service, food, and childcare businesses in Winter Springs.

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Equestrian Facility With Covered Arena
Equestrian Facility With Covered Arena

3287 N COUNTY ROAD 426, Geneva, FL 32732

$1,630,000
4,066 sqft 10.06 AC lot

Established horse property with barns, arenas, paddocks, residences, and support facilities for ongoing equine operations.

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Multi-Tenant Shopping Center
Multi-Tenant Shopping Center

767 S State Rd 434, Altamonte Springs, FL 32714

$3,009,500
6,543 sqft

The fully leased retail property sits along a state road with nearby college, healthcare, and grocery destinations.

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Equestrian Facility with Covered Arena
Equestrian Facility with Covered Arena

2121 Dressage Cove, Chuluota, FL 32766

$4,650,000
46,861 sqft 38.89 AC lot

Multi-building equine compound with residences, barns, paddocks, and dedicated operational infrastructure.

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Seminole County, FL Commercial Real Estate Market Trends and Statistics

Explore 330 commercial real estate for sale in Seminole County, FL, showcased through 330 active listings on our real estate platform. These investment opportunities span a total of 4,657,493 square feet of properties for sale, with an estimated market value of $299,966,718.

Sale prices for business properties in Seminole County, FL start at $34,950, averaging $1,369,711, and reaching up to $9,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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