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    Big Pine Key, FL Commercial Real Estate for Sale

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    Little Torch Key, FL Cudjoe Key, FL Key Colony Beach, FL
    10 listings
    High-Visibility Commercial Property in Big Pine
    $3,100,000
    5,250 SF
    High-Visibility Commercial Property in Big Pine

    30330 - 30348 Overseas Highway, Big Pine Key, FL 33043

    Prime commercial property with high traffic and income potential.
    • Prime commercial location on Big Pine Key with 215 feet of high‑visibility frontage on Overseas Highway (U.S. 1), near the island's only traffic light and major retailers.
    • Substantial income‑producing property with 5,250 sq. ft. of retail space occupied by 9 tenants, including long‑term tenants (15+ years), plus additional yard space rentals and a 200' radio tower for potential added revenue.
    • Solid concrete construction with robust roofing system providing exceptional structural strength and durability.
    • Rare opportunity to own commercial land (35,475 sq. ft.) in the Florida Keys.
    • Buildings are elevated and equipped with a handicap‑accessible ramp servicing all retail spaces.
    Updated: Dec 10, 2025
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    Commercial Land in Big Pine
    $895,000
    0.72 Acres
    Commercial Land in Big Pine

    30582 5th Avenue, Big Pine Key, FL 33043

    Six contiguous commercially zoned lots totaling approximately 31,500 square feet.
    • Six contiguous commercially zoned lots totaling approximately 31,500 sq ft.
    • Flexible commercial zoning allows for a variety of uses, contractor storage, or redevelopment.
    • Includes both 30562 and 30582 5th Avenue.
    • 150' x 210' site dimensions.
    • Mix of cleared land and existing structure.
    Updated: Apr 13
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    Commercial Waterfront Land with Deep-Water Access
    $420,000
    0.14 Acres
    Commercial Waterfront Land with Deep-Water Access

    Zoned for commercial fishing with deep-water canal access to both the Gulf and Atlantic, plus an included trailer.

    29517 Big Pine Street, Big Pine Key, FL 33043

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    Oceanfront Bed and Breakfast Opportunity
    $3,899,000
    Oceanfront Bed and Breakfast Opportunity

    Waterfront B&B in Big Pine Key with income potential.

    1557 Long Beach Dr, Big Pine Key, FL 33043

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    Land Parcel Off US-1
    $120,000
    0.09 Acres
    Land Parcel Off US-1

    Commercial land parcel with high visibility and accessibility.

    Vacant Land lot: 6, Big Pine Key, FL 33043

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    NNN Leased Property in Keys
    $3,500,000
    8,810 SF
    NNN Leased Property in Keys

    100% NNN leased property with a national A-rated tenant.

    30251 Overseas Hwy, Big Pine Key, FL 33043

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    Commercial Land in Big Pine
    $920,000
    0.86 Acres
    Commercial Land in Big Pine

    Commercial zoned wooded lot in Big Pine Key, Florida.

    Overseas N Us Highway 1, Big Pine Key, FL 33043

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    High-Visibility Commercial Property on Overseas Highway
    $3,100,000
    5,250 SF
    High-Visibility Commercial Property on Overseas Highway

    Commercial property with 5,250 SF retail space on 35,475 SF land.

    Big Pine Key, FL 33043

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    Oceanfront Bed and Breakfast Opportunity
    $3,899,000
    3,029 SF
    Oceanfront Bed and Breakfast Opportunity

    Waterfront property with income potential in the Florida Keys.

    1557 Long Beach Dr, Big Pine Key, FL 33043

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    Commercially Zoned Land on A1A
    Contact for pricing
    1.45 Acres
    Commercially Zoned Land on A1A

    1.453 acre commercially zoned land with highway frontage.

    30464 Overseas Hwy, Big Pine Key, FL 33043

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    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 10 Active listings in Big Pine Key, FL, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 62 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Ramrod Key Commercial Property
    $1,250,000
    1,234 SF
    Ramrod Key Commercial Property

    Commercial property on Ramrod Key with highway frontage.

    27001 Overseas Highway, Ramrod Key, FL 33042

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    Florida Keys Income-Producing Assets
    $12,250,000
    1.67 Acres
    Florida Keys Income-Producing Assets

    Rare opportunity: licenses, restaurant, hotel, dive shop, and vessel.

    27340 Overseas Highway, Ramrod Key, FL 33042

    View details
    Commercially Zoned Land Parcel
    $225,000
    0.17 Acres
    Commercially Zoned Land Parcel

    Vacant land parcel on Overseas Highway in Ramrod Key.

    26837 Overseas Highway, Summerland Key, FL 33042

    View details
    Commercial Lot on Cudjoe Key
    $275,000
    Commercial Lot on Cudjoe Key

    Vacant commercial lot with highway frontage near popular establishment.

    Summerland Key, FL 33042

    View details

    Off-Market Properties in Big Pine Key, FL

    Consider similar Off-Market properties in Big Pine Key, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    31044 Ave B B
    RESTAURANT
    3,252 SF Lot: 0.11 Acres
    Estimated value
    $740,000

    31044 Ave B B, Big Pine Key, FL 33043-4507

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    1557 Long Bch Dr
    HOTEL/MOTEL
    2,315 SF Lot: 0.80 Acres

    1557 Long Bch Dr, Big Pine Key, FL 33043-3511

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    30410 Seagrape Ter
    OFFICE BUILDING
    2,440 SF Lot: 0.24 Acres
    Estimated value
    $640,000

    30410 Seagrape Ter, Big Pine Key, FL 33043-3436

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    3rd Ave, Unit 1
    STORAGE YARD, OPEN STORAGE
    Lot: 0.92 Acres
    Value Estimation by Request
    Unit 1

    3rd Ave, Big Pine Key, FL 33043

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    540 Key Deer Blvd
    OFFICE BUILDING
    666 SF Lot: 1.52 Acres
    Value Estimation by Request

    540 Key Deer Blvd, Big Pine Key, FL 33043-4910

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    30770 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    5,600 SF Lot: 1.71 Acres
    Estimated value
    $3,500,000

    30770 Overseas Hwy, Big Pine Key, FL 33043-3420

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    31133 Ave A A
    VEHICLE SALES, RENTALS
    2,460 SF Lot: 0.52 Acres
    Estimated value
    $1,250,000

    31133 Ave A A, Big Pine Key, FL 33043-4502

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    30646 Overseas Hwy
    PROFESSIONAL BUILDING
    1,025 SF Lot: 0.43 Acres
    Value Estimation by Request

    30646 Overseas Hwy, Big Pine Key, FL 33043-3423

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    30387 Quail Roost Trl
    RETAIL STORES (PERSONAL SERVICES)
    2,500 SF Lot: 1.01 Acres
    Value Estimation by Request

    30387 Quail Roost Trl, Big Pine Key, FL 33043-3350

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    30330 Overseas Hwy
    MINI-MALL
    5,250 SF Lot: 0.82 Acres

    30330 Overseas Hwy, Big Pine Key, FL 33043-3352

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    31067 Ave A A
    VACANT COMMERCIAL LAND
    Lot: 0.09 Acres
    Value Estimation by Request

    31067 Ave A A, Big Pine Key, FL 33043-4574

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    2875 Central Ave
    DISTRIBUTION WAREHOUSE
    1,080 SF Lot: 0.15 Acres
    Value Estimation by Request

    2875 Central Ave, Big Pine Key, FL 33043-6227

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    2875 Central Ave, Unit R
    VACANT COMMERCIAL LAND
    Lot: 0.15 Acres
    Value Estimation by Request
    Unit R

    2875 Central Ave, Big Pine Key, FL 33043-6227

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    Northridge Rd
    VACANT COMMERCIAL LAND
    Lot: 0.15 Acres
    Value Estimation by Request

    Northridge Rd, Big Pine Key, FL 33043

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    Big Pine Key, FL Commercial Real Estate Investment Opportunities Market Analysis

    Explore 72 commercial real estate for sale in Big Pine Key, FL, showcased through 10 active listings on our real estate platform. These investment opportunities span a total of 22,339 square feet of properties for sale, with an estimated market value of $13,599,000.

    Sale prices for business properties in Big Pine Key, FL start at $3,100,000, averaging $3,399,750, and reaching up to $3,899,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Demographics Overview

    Population 4,632
    Population Growth (5Y) -6.0%
    Median Household Income $92,955
    College Educated 36.6%

    High-Yield Neighborhoods for Investment

    Identify Big Pine Key submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    33043 $2.4M

    Taxes & Financing

    Tax Rate (average for all types) 0.87%
    Property Tax per SF $12.38 per SF
    Tax Rate vs County Average 0.13 pp above county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Monroe County

    New Delisted

    Total CRE Inventory on Market (SF)

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