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    Key Largo, FL Commercial Real Estate for Sale

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    Lehigh Acres, FL Cape Coral, FL Port Charlotte, FL
    35 results
    Key Largo Inn Investment Opportunity
    $14,800,000

    Key Largo Inn Investment Opportunity

    99202 Overseas Highway, Key Largo, FL 33037

    Turnkey inn with restaurant, bar, and development potential.

    • Turnkey, income‑producing inn in a prime Key Largo location.
    • Includes 50 transferable transient licenses (nightly rentals) offering exceptional short‑term rental income.
    • Features a 5COP full liquor license for the on‑site restaurant and bar.
    • 50 total guest rooms, including 12 spacious two‑room suites.
    • Highly visible location with 450 feet on US 1 and 9 parcels included.
    Updated: Apr 11
    View details
    Prime US-1 Mixed-Use Opportunity
    $2,995,000

    Prime US-1 Mixed-Use Opportunity

    92295 Old State Road, Key Largo, FL 33070

    Mixed-use commercial building with highway frontage in Tavernier!

    • Seller financing available: $500,000 down, 6% interest, 20‑year amortization, and a 5‑year balloon.
    • Prime US‑1 highway frontage (313 feet) in Tavernier, offering exceptional visibility.
    • Mixed‑use commercial building with approximately 6,214 sq. ft. of space on a 37,477 sq. ft. fenced lot.
    • Six separate units/suites, each with a half bathroom.
    • Excellent accessibility on the northbound side of US‑1 with convenient access to the southbound lane.
    Updated: Apr 13
    View details
    Key Largo Vacant RV Lot
    $300,000

    Key Largo Vacant RV Lot

    Vacant RV lot in Key Largo Kampground & Marina.

    101551 Overseas Highway, Key Largo, FL 33037
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    Highway Frontage Commercial Building
    Contact for pricing

    Highway Frontage Commercial Building

    Commercial building with highway frontage and upstairs space for lease.

    106600 Overseas Highway, Key Largo, FL 33037
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    Iconic Waterfront Restaurant and Bar
    $4,900,000

    Iconic Waterfront Restaurant and Bar

    Legendary waterfront restaurant/bar with long-term lease in Key Largo, FL.

    58000 Card Sound Road, Key Largo, FL 33037
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    Oceanfront Estates with Development Potential
    $9,500,000

    Oceanfront Estates with Development Potential

    Oceanfront estates with vacation rental income and development opportunities.

    95351 Overseas Highway, Key Largo, FL 33037
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    Key Largo Restaurant with Drive-Through
    $2,199,000

    Key Largo Restaurant with Drive-Through

    Profitable franchise with real estate and drive-through in Key Largo.

    92661 Overseas Highway, Key Largo, FL 33037
    View details
    Key Largo Retail Investment Opportunity
    $2,965,000

    Key Largo Retail Investment Opportunity

    2,400 SF building with adjacent lot in Key Largo.

    102970 Overseas Highway, Key Largo, FL 33037
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    Key Largo Commercial Space Available
    Contact for pricing

    Key Largo Commercial Space Available

    5,457 sqft commercial space in Key Largo for lease.

    99451 Overseas Highway, Key Largo, FL 33037
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    Waterfront Property for Rehab/Assisted Living
    $13,499,000

    Waterfront Property for Rehab/Assisted Living

    Waterfront property ideal for rehab center or assisted living facility.

    97340-60 Overseas Highway, Key Largo, FL 33037
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    Key Largo Commercial Lot
    $457,000

    Key Largo Commercial Lot

    Commercial lot with frontage on Overseas Highway in Key Largo.

    104.5 Mm 104 5 Overseas Highway, Key Largo, FL 33037
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    Private Island with Marina
    Contact for pricing
    26.00 Acres

    Private Island with Marina

    26-acre private island with marina and mainland home.

    10 Cannon Point, Key Largo, FL 33037
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    Unfinished Retail Space Opportunity
    Contact for pricing

    Unfinished Retail Space Opportunity

    Second floor unfinished retail space available for sale.

    106600 Overseas Highway, Key Largo, FL 33037
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    Key Largo Lot with RV
    $319,000
    0.03 Acres

    Key Largo Lot with RV

    Lot with RV in Key Largo, short-term rentals allowed.

    325 Calusa St #5, Key Largo, FL 33037
    View details
    Commercial Building Lot Opportunity
    $1,295,000

    Commercial Building Lot Opportunity

    Approved site plan for a 2,500 sq. ft. commercial building.

    101201 Overseas Highway, Key Largo, FL 33037
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    Key Largo Oceanside Commercial Building
    $5,400,000

    Key Largo Oceanside Commercial Building

    Commercial building with deep water dockage and direct ocean access.

    522 Caribbean Drive, Key Largo, FL 33037
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    Key Largo Retail Investment Opportunity
    $2,965,000
    0.46 Acres

    Key Largo Retail Investment Opportunity

    2,400 SF building with adjacent lot in Key Largo.

    102970 Overseas Hwy, Key Largo, FL 33037
    View details
    Key Largo Mixed-Use Property
    $1,790,000

    Key Largo Mixed-Use Property

    High-visibility mixed-use property with commercial storefront and residential apartment.

    100636 Overseas Highway, Key Largo, FL 33037
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    Oceanside Marina in Florida Keys
    $5,000,000

    Oceanside Marina in Florida Keys

    Marina with deep-water dockage, RV pads, and investment potential.

    199 Morris Avenue, Key Largo, FL 33037
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    Luxury Residences at Fisherman's Cove
    $299,000
    2,300 SF

    Luxury Residences at Fisherman's Cove

    Fractional ownership of designer-decorated residences with resort-style amenities.

    104000 Overseas Highway, Key Largo, FL 33037
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    Key Largo Auto/Marine Repair Facility
    $4,000,000
    4,000 SF

    Key Largo Auto/Marine Repair Facility

    Turnkey auto and marine repair facility on Overseas Highway.

    98250 Overseas Hwy, Key Largo, FL 33037
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    Key Largo Boutique Hotel For Sale
    $13,775,000

    Key Largo Boutique Hotel For Sale

    21-room boutique hotel on nearly 3 acres in Key Largo.

    000 Overseas Highway, Key Largo, FL 33037
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    Key Largo Storage and Marina
    Contact for pricing

    Key Largo Storage and Marina

    Storage and marina with dockage in Key Largo, Florida.

    106600 Overseas Highway, Key Largo, FL 33037
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    Vacant Land in Key Largo
    $355,000

    Vacant Land in Key Largo

    Vacant land near pool with water access in Key Largo.

    325 Calusa Street, Key Largo, FL 33037
    View details

    Key Largo, FL Commercial Real Estate Investment Opportunities Market Analysis

    Explore 35 commercial real estate for sale in Key Largo, FL, showcased through 35 active listings on our real estate platform. These investment opportunities span a total of 1,742,901 square feet of properties for sale, with an estimated market value of $122,500,000.

    Sale prices for business properties in Key Largo, FL start at $319,000, averaging $13,611,111, and reaching up to $75,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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