Matlacha Isles, FL Commercial Real Estate for Sale

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North Fort Myers, FL Lehigh Acres, FL Fort Myers, FL Miami, FL
663 properties
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Two-Story Retail Building
Updated: Sep 11
Two-Story Retail Building

3724 Del Prado Boulevard S, Cape Coral, FL 33904

$2,195,000
0.57 AC lot
Approximately 6,062 SF enclosed building area and approximately 6,720 gross SF
0.574‑acre site with approximately 200 feet of Del Prado Boulevard frontage
Two‑story layout with restaurant plus three service‑retail suites
Restaurant seats approximately 200 people and includes a full‑service bar and commercial kitchen
Roof replaced in 2023; building constructed in 1977
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Two-Unit Office Building
Updated: Oct 7
Two-Unit Office Building

1224 & 1228 Lafayette Street, Cape Coral, FL 33904

$1,275,000
0.21 AC lot
Two office suites: 1,550 square feet and 1,450 square feet
Adjoining lot measures 0.214 acres
Architect occupies one suite; civil engineer occupies the other
Second‑suite tenant is open to a longer lease with a new owner
Built in 1972; building has undergone recent remodeling
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Two-Story Retail Building with Patios
Two-Story Retail Building with Patios

1313 SE 47th Terrace, Cape Coral, FL 33904

$1,350,000
0.15 AC lot

Two-level commercial space with patio areas and a layout that can accommodate one or two businesses.

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Two-Story Mixed-Use Property
Two-Story Mixed-Use Property

3724 Del Prado Blvd S, Cape Coral, FL 33904

$2,195,000
6,062 sqft

Freestanding commercial building with an operating restaurant, three service-retail suites, separate entrances, and on-site parking.

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Two-Unit Retail Property
Two-Unit Retail Property

1336 Cape Coral Parkway E, Cape Coral, FL 33904

$1,300,000
0.14 AC lot

Leased retail building with updated roof and HVAC plus parking at the front and rear.

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Two-Unit Office Building
Two-Unit Office Building

1615 SE 47th Terrace, Cape Coral, FL 33904

$1,072,000
0.22 AC lot

SC-zoned commercial property with one unit currently occupied by a bakery tenant.

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Fully Leased Office Building
Fully Leased Office Building

1314-1322 Lafayette Street, Cape Coral, FL 33904

$1,295,000
0.42 AC lot

Five configured office units are fully occupied, with a new roof, new A/C systems, and updated plumbing.

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Two-Story Professional Office Building
Two-Story Professional Office Building

1323 Viscaya Parkway, Cape Coral, FL 33990

$1,250,000
4,865 sqft 0.34 AC lot

Commercially zoned office property with medical use potential, on-site parking, and an existing tax and accounting service occupant.

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Commercial Land Near Industrial Park
Commercial Land Near Industrial Park

1217 NE 23rd Terrace, Cape Coral, FL 33909

$995,000
1.61 AC lot

Commercial land positioned within North Cape’s expanding employment and development corridor.

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Commercial Land
Commercial Land

428-444 Andalusia Boulevard, Cape Coral, FL 33909

$1,400,000
1.10 AC lot

CC zoning within the Pine Island Road District supports retail, medical, and professional office uses.

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Two-Story Bar & Pub Building
Two-Story Bar & Pub Building

1313 SE 47th Terrace, Cape Coral, FL 33904

$1,350,000
5,920 sqft

Flexible hospitality layout with patio areas and the option to operate as one business or two separate units.

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Commercial Land Along Pine Island Road
Commercial Land Along Pine Island Road

Pine Island Rd NE, Cape Coral, FL 33909

$766,000
0.57 AC lot

Assembled parcel bordered by city-owned land designated for public parking, with city water already in place.

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Commercial Land Across From Publix
Commercial Land Across From Publix

1712 Kismet Parkway E, Cape Coral, FL 33909

$749,900
0.48 AC lot

Development parcel positioned along Kismet Pkwy E within Cape Coral’s North Cape commercial corridor.

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Office, Retail & Flex Portfolio
Office, Retail & Flex Portfolio

1328 Lafayette St & 1323-1325, 1403 Miramar St, Cape Coral, FL 33904

$3,350,000
14,893 sqft

The assemblage combines adaptable buildings with conditioned office and warehouse areas and roll-up door access.

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Commercial Land with City Water
Commercial Land with City Water

Pine Island Rd NE, Cape Coral, FL 33909

$779,000
0.72 AC lot

Commercial parcel with city water in place and adjacent city-owned land designated for public parking.

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Commercial Land Across From Publix
Commercial Land Across From Publix

1720 Kismet Parkway E, Cape Coral, FL 33909

$749,900
0.23 AC lot

Commercial land positioned across from Publix near the Kismet Parkway E and Del Prado Boulevard N intersection.

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Two-Suite Office Building
Two-Suite Office Building

1224 & 1228 Lafayette St, Cape Coral, FL 33904

$1,275,000
3,000 sqft

Two occupied office suites offer distinct footprints for professional operations.

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Commercial Land Across From Publix
Commercial Land Across From Publix

1724 Kismet Parkway E, Cape Coral, FL 33909

$749,900
0.23 AC lot

Commercial land near Del Prado Boulevard, established residential development, and planned public improvement projects.

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Fitness Center with Outdoor Courts
Fitness Center with Outdoor Courts

326 SW 2nd Ter, Cape Coral, FL 33991

$2,950,000
8,550 sqft 2.30 AC lot

2019 concrete block facility with a tenant-occupied training area, private office, solar panels, and expansion room.

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Commercial Land Across From Publix
Commercial Land Across From Publix

1812 Kismet Parkway E, Cape Coral, FL 33909

$749,900
0.23 AC lot

Commercial land on Kismet Parkway E near Del Prado Boulevard N, positioned within North Cape’s commercial corridor.

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Industrial Building with Fenced Storage
Industrial Building with Fenced Storage

1215 SE 10 ST, Cape Coral, FL 33990

$3,000,000
12,023 sqft 1.05 AC lot

12,023 SF industrial building includes fenced outdoor storage and six overhead doors on 1.05 acres.

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Commercial Land Across from Publix
Commercial Land Across from Publix

1808 Kismet Parkway E, Cape Coral, FL 33909

$749,900
0.23 AC lot

Positioned on Kismet Pkwy E near Del Prado Blvd N and established residential development.

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Leased Professional Office Building
Leased Professional Office Building

1314-1322 Lafayette St, Cape Coral, FL 33904

$1,295,000
6,498 sqft

Fully leased office building configured as five units, with improvements including a new roof, new A/C, and updated plumbing.

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Entitled Mixed-Use Development Site
Entitled Mixed-Use Development Site

570 NE 4th Terrace, Cape Coral, FL 33909

$1,895,000
0.69 AC lot

Approved plans allow workforce residences alongside contractor-oriented commercial suites.

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Matlacha Isles, FL Commercial Real Estate Market Trends and Statistics

Explore 663 commercial real estate for sale in Matlacha Isles, FL, showcased through 663 active listings on our real estate platform. These investment opportunities span a total of 1,555,096 square feet of properties for sale, with an estimated market value of $332,018,455.

Sale prices for business properties in Matlacha Isles, FL start at $30,000, averaging $653,579, and reaching up to $17,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 26K
Population Growth (5Y) +16.3%
Median Household Income $82,927
College Educated 33.2%

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New vs delisted commercial listings in Lee County

New Delisted

Total CRE Inventory on Market (SF)

Average Property Price per SF

For-sale Residential Income pricing trends in Lee County

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