Matlacha Isles, FL Commercial Real Estate for Lease

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116 properties
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First-Floor Office Suite
Updated: Aug 16
First-Floor Office Suite

1325 SE 47th Street, Cape Coral, FL 33904

$2,750/Mo
0.17 AC lot
1,186 SF first‑floor office suite
Open lobby and reception area with vaulted ceilings
Three private offices and a conference room
Kitchenette plus large storage closet/file station
South‑facing windows overlooking the parking lot
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Flex Space with Office and Warehouse
Updated: Aug 3
Flex Space with Office and Warehouse

4519 SE 16th Place, Cape Coral, FL 33904

$3,000/Mo
0.41 AC lot
Approximately 1,000 sf of warehouse space
Roughly 18' x 18' air‑conditioned office with two street‑facing windows
12' overhead door and 14 foot ceilings
ADA compliant restroom
3 designated parking spaces behind the unit
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Second-Floor Office Unit
Second-Floor Office Unit

923 Del Prado Boulevard S, Cape Coral, FL 33990

$2,450/Mo
0.16 AC lot

Configured with reception, private offices, conference space, storage, and a full-size refrigerator.

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Remodeled Medical Office Space
Remodeled Medical Office Space

1224 Del Prado Boulevard S C, Cape Coral, FL 33990

$16 SF/Yr
3,352 sqft

Updated professional space combines medical functionality, reception, storage, and dedicated parking.

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Executive Office Suite
Executive Office Suite

4706 Chiquita Boulevard S, Cape Coral, FL 33914

$585/Mo per office
1.00 AC lot

Office executive suites with 24/7 access, shared business services, and conference rooms available for rental.

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Ground-Floor Office Units
Ground-Floor Office Units

4645 SE 15th Avenue, Cape Coral, FL 33904

$2,500/Mo
0.16 AC lot

Professional workspace with private offices, a kitchen, two bathrooms, parking, and utilities included in the lease.

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Renovated Office Suite with Private Restroom
Renovated Office Suite with Private Restroom

1416 Lafayette Street, Cape Coral, FL 33904

$1,600/Mo
0.21 AC lot

Newly renovated downtown suite includes a front office/reception and separate air-conditioned rear workspace with private restroom.

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Second-Floor Office Unit
Second-Floor Office Unit

203-923 Del Prado Blvd S, Cape Coral, FL 33909

$2,450/Mo
1,015 sqft

Professional suite with private offices, conference space, reception, storage, and a full-size refrigerator.

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Two-Bath Office Suite
Two-Bath Office Suite

131 Del Prado Boulevard S, Cape Coral, FL 33990

$3,800/Mo

Large office space on Del Prado Boulevard S with two bathrooms and room for substantial office use.

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Storefront Commercial Space
Storefront Commercial Space

131 Del Prado Boulevard S, Cape Coral, FL 33990

$2,100/Mo

Commercial space at 131 Del Prado Boulevard S, with a 2007 construction year.

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Mall Plaza Retail Suite
Mall Plaza Retail Suite

1404 Del Prado Blvd S Ste 165, Cape Coral, FL 33990

$21 SF/Yr
1,620 sqft

Retail unit within Del Prado Mall plaza with a clean, open layout and access off Del Prado Blvd S.

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Flex Space with Warehouse Doors
Flex Space with Warehouse Doors

954 Country Club Boulevard, Cape Coral, FL 33990

$4,150/Mo
0.42 AC lot

Includes office rooms, a conference room, and open warehouse space.

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12-Unit Flex Office/Warehouse
12-Unit Flex Office/Warehouse

829 NE Pine Island Lane, Cape Coral, FL 33909

$1,920/Mo
0.28 AC lot

Concrete block flex property with individual office, restroom, warehouse areas, ample parking, and high ceilings.

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Freestanding Flex Showroom Building
Freestanding Flex Showroom Building

910/912 Del Prado Blvd S, Cape Coral, FL 33990

$18 SF/Yr
9,188 sqft

Standalone building on Del Prado Boulevard South with flexible interior layout and on-site parking for retail, showroom, service, or light industrial use.

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First-Floor Office Unit
First-Floor Office Unit

923 Del Prado Boulevard S, Cape Coral, FL 33990

$2,250/Mo
0.16 AC lot

Lobby, reception, private offices, kitchenette, and storage create a practical workplace layout.

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Office Units Near Midpoint Bridge
Office Units Near Midpoint Bridge

2930 Del Prado Boulevard S, Cape Coral, FL 33904

$1,575/Mo
0.34 AC lot

Cape Coral office space along Del Prado Boulevard S, positioned south of the Midpoint Bridge.

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Retail Space with New Finishes
Retail Space with New Finishes

1910 Del Prado Boulevard S, Cape Coral, FL 33990

$22 SF/Yr
2,850 sqft

C1 Commercial zoning, alley service access, and convenient entry from Del Prado Boulevard support retail use.

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Air-Conditioned Flex Space
Air-Conditioned Flex Space

4427 SE 16th Place, Cape Coral, FL 33904

$2,500/Mo
0.30 AC lot

Multi-tenant commercial property with office accommodations, workspace, and an overhead-door warehouse component.

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Flex Warehouse with Overhead Doors
Flex Warehouse with Overhead Doors

1056 NE Pine Island Rd, Cape Coral, FL 33990

$2,750/Mo
2,000 sqft

Recently renovated flex warehouse configuration with 17’ clear height and hurricane-rated overhead doors for versatile tenant use.

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Flex Space with Office Areas
Flex Space with Office Areas

1913 NE 10th Terrace, Cape Coral, FL 33909

$2,291-$14,583/Mo
0.55 AC lot

Under-construction commercial space offers divisible warehouse units with office areas and three-phase electrical service.

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Gulf Access Duplex Rental with Lanai
Gulf Access Duplex Rental with Lanai

4931 VICTORIA DRIVE, Cape Coral, FL 33904

$1,650/Mo
800 sqft

Freshly updated 2 bed, 2 bath Gulf Access duplex with enclosed lanai, in-unit washer/dryer, and about 80 feet of water frontage.

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Second-Floor Office Suite
Second-Floor Office Suite

3613 Del Prado Boulevard S, Cape Coral, FL 33904

$3,200/Mo

Second-floor office suite with four enclosed offices and a large open work area.

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Professional Office Suite
Professional Office Suite

4020 Del Prado Boulevard S B-3, Cape Coral, FL 33904

$1,975/Mo
4,825 sqft 0.59 AC lot

Open-plan workspace with private offices, storage, and an in-suite restroom at a signalized intersection.

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Retail Space With Pylon Signage
Retail Space With Pylon Signage

814 SW Pine Island Road, Cape Coral, FL 33991

$2,500-$5,000/Mo
3.65 AC lot

Flexible retail or office space offers a finished layout, dual HVAC, two bathrooms, and covered sidewalks.

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Matlacha Isles, FL Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Matlacha Isles, FL with 116 listings featured on our commercial real estate exchange. The current inventory includes 506,844 square feet of properties with an estimated lease value of $709.31.

Estimated lease rates for Commercial real estate in Matlacha Isles, FL begin at $1.77 SF/Yr, with an average of $20.86 SF/Yr and extend to $75 SF/Yr.
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