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    Daniel Island, SC Commercial Real Estate for Lease

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    231 results
    Charleston Historic District Office Space
    $22 SF/Yr
    4,204 SF

    Charleston Historic District Office Space

    2 Cumberland St, Charleston, SC 29401

    Renovated office suites with harbor views in historic Charleston.

    • Rare views of Charleston Harbor, Ravenel Bridge, US Customs House, and USS Yorktown.
    • Newly renovated suites with modern finishes ready for immediate occupancy.
    • Located in the historic district of Charleston's peninsula.
    • Open floorplans provide functional versatility.
    • Suites available on the 2nd and 3rd floors, each with 4,204 RSF.
    Updated: Mar 6
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    West Ashley Retail Space Available
    $33 SF/Yr
    2,983 SF

    West Ashley Retail Space Available

    3863 West Ashley Circle, Charleston, SC 29414

    Retail space in shopping center anchored by Harris Teeter.

    • Anchored by the #1 visited Harris Teeter in the state.
    • Located in a high‑growth residential area with 44,021 housing units within 5 miles and 4,500 proposed homes.
    • Easy access with multiple points of ingress/egress.
    • Close proximity to other shops, schools, recreation facilities, and Walmart Supercenter.
    • Built in 2019.
    Updated: Mar 7
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    Class A Office Space
    $37 SF/Yr
    5,153 SF

    Class A Office Space

    Class A office space in downtown Charleston for lease.

    40 Calhoun Street, Charleston, SC 29401
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    Prime Retail Space on King
    $75 SF/Yr
    3,740 SF

    Prime Retail Space on King

    High-profile retail space in downtown Charleston near Charleston Place.

    229 King St, Charleston, SC 29401
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    Downtown Charleston Freestanding Building
    $29 SF/Yr
    14,518 SF

    Downtown Charleston Freestanding Building

    Freestanding building in historic downtown Charleston with on-site parking.

    276 East Bay Street, Charleston, SC 29401
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    Prime Showroom/Office/Automotive Space Available
    $8,700,000 SF/Yr
    24,000 SF

    Prime Showroom/Office/Automotive Space Available

    Rare opportunity on US Hwy 17 corridor in West Ashley.

    2137 Savannah Highway, Charleston, SC 29414
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    Wappoo Creek Office Space Available
    $20 SF/Yr
    2,944 SF

    Wappoo Creek Office Space Available

    Office space for lease in a convenient Charleston location.

    125 Wappoo Creek Dr, Charleston, SC 29412
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    Daniel Island Office Space Available
    $32 SF/Yr
    3,975 SF

    Daniel Island Office Space Available

    Second-floor office suite in Daniel Island's Town Center.

    115 Riverlanding Dr, Charleston, SC
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    James Island Office Space Available
    $20 SF/Yr
    2,200 SF

    James Island Office Space Available

    Office space for lease in a convenient Charleston location.

    125 Wappoo Creek Dr, Charleston, SC 29412
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    Prime Retail Space on George
    $45 SF/Yr
    2,030 SF

    Prime Retail Space on George

    Retail space for lease in downtown Charleston near King Street.

    51 George Street, Charleston, SC 29401
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    Class A Office Space
    $43 SF/Yr
    9,675 SF

    Class A Office Space

    Multi-tenant office building in Charleston's Historic District.

    100 Calhoun Street, Charleston, SC 29401
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    Office Suite with Direct Elevator
    $42 SF/Yr
    2,625 SF

    Office Suite with Direct Elevator

    Third-floor office suite with open workspace and outdoor patio.

    121 Calhoun St, Charleston, SC 29401
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    Prime Retail Space on George
    $45 SF/Yr
    3,641 SF

    Prime Retail Space on George

    Retail space for lease in downtown Charleston near King Street.

    51 George Street, Charleston, SC 29401
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    Charleston Historic District Office Space
    $22 SF/Yr
    16,816 SF

    Charleston Historic District Office Space

    Renovated office suites with harbor views in Charleston's historic district.

    2 Cumberland St, Charleston, SC 29401
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    Retail Space in James Island
    $38 SF/Yr
    90,993 SF

    Retail Space in James Island

    Retail space for lease in a high-traffic shopping center.

    1739 Maybank Highway, Charleston, SC 29412
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    Renovated Office Space on King
    $23 SF/Yr
    2,631 SF

    Renovated Office Space on King

    Renovated office space in Charleston's 'Dine & Design' district.

    579 King Street, Charleston, SC 29403
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    Wentworth Street Retail/Fitness Opportunity
    $32 SF/Yr
    9,677 SF

    Wentworth Street Retail/Fitness Opportunity

    Retail or fitness space available in Charleston's shopping district.

    69 Wentworth Street, Charleston, SC
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    Office and Medical Suites Available
    $650/Mo
    309 SF

    Office and Medical Suites Available

    Two-story building with executive and medical suites for lease.

    3618 Ashley Phosphate Road, Charleston, SC 29418
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    Class A Office Space Available
    $22 SF/Yr
    20,028 SF

    Class A Office Space Available

    Class A office suite for lease in growing Daniel Island/Cainhoy.

    1951 Clements Ferry, Charleston, SC 29492
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    Historic Mixed-Use Building on King
    $35 SF/Yr
    10,673 SF

    Historic Mixed-Use Building on King

    Renovated mixed-use building in Charleston's Upper King Street corridor.

    438 King St, Charleston, SC 29403
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    Office Complex Near Citadel Mall
    $24 SF/Yr
    9,275 SF

    Office Complex Near Citadel Mall

    Three-building office complex on 10.82 acres with ample parking.

    1 South Park Circle, Charleston, SC 29407
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    Move-in Ready Office/Retail Space
    $44 SF/Yr

    Move-in Ready Office/Retail Space

    Office or retail space with on-site parking on Shem Creek.

    103 Church Street, Charleston, SC 29464
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    Daniel Island, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Daniel Island, SC with 231 listings featured on our commercial real estate exchange. The current inventory includes 1,085,170 square feet of properties with an estimated lease value of $8,780,804.

    Estimated lease rates for Commercial real estate in Daniel Island, SC begin at $2 SF/Yr, with an average of $72,568 and extend to $8,700,000.
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