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San Bruno, CA Commercial Real Estate for Lease

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12 results
Professional Medical Office Building
$45 SF/Yr
32,658 SF

Professional Medical Office Building

1001 Sneath Lane, San Bruno, CA 94066

Professional medical office building in a prime location with ample parking.

  • Prime location in San Bruno, San Mateo County with easy access to HWY 101, 280, and 380.
  • Professional medical office building suitable for private medical practices.
  • High‑end medical buildout already in place.
  • Abundant on‑site parking available.
  • Large reception and waiting area.
Updated: Jan 27
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San Bruno Office Suites Available
Contact for pricing
3,141 SF

San Bruno Office Suites Available

931 San Bruno Avenue West, San Bruno, CA 94066

Medical or general office suites available for rent.

  • Two Medical or General Office Suites totaling 3,141 SF
  • Divisible to 1,359 and 1,782 SF
  • Build to Suit Dental Office Improvements Available
  • Layout consists of open area, private offices, kitchen, restroom
  • 2 Large Monument signs on San Bruno Ave
Updated: Apr 15
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San Bruno Office Space Available
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San Bruno Office Space Available

Office space for rent with shuttle to transit stations.

801-851 Traeger Avenue, San Bruno, CA 94066
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Retail Space in San Bruno
Contact for pricing

Retail Space in San Bruno

Established shopping center anchored by Mollie Stone’s in San Bruno.

851 Cherry Avenue, San Bruno, CA 94066
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Class A Office Space Available
$4 SF/Yr
1,512 SF

Class A Office Space Available

Improved Class A office space near SFO and public transit.

801 Traeger Ave, San Bruno, CA
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San Bruno Commercial Space Available
Contact for pricing
5,135 SF

San Bruno Commercial Space Available

Commercial space available for rent in San Bruno, CA.

1142-1178 Cherry Ave, San Bruno, CA 94066
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Prime Location Retail/Office Space
$5,900 /Mo
2,000 SF

Prime Location Retail/Office Space

2000 SF retail/office space with ample parking.

El Camino Real, San Bruno, CA 94066
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Retail Space Near Tech Hub
Contact for pricing
4,003 SF

Retail Space Near Tech Hub

Retail space available near YouTube, Google, and Walmart Labs.

899 Cherry Ave, San Bruno, CA
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San Bruno Warehouse Space Available
$2 SF/Yr
5,135 SF

San Bruno Warehouse Space Available

Industrial warehouse space for lease in San Bruno, California.

1142-1178 Cherry Ave, San Bruno, CA
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San Bruno Flex Space Available
$2 SF/Yr
3,600 SF

San Bruno Flex Space Available

Flex space featuring 1,000 SF office and grade-level loading.

1051-1099 Sneath Ln, San Bruno, CA
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San Bruno Retail Space Available
Contact for pricing
9,590 SF

San Bruno Retail Space Available

9,590 SF retail space for rent in San Bruno.

855-875 El Camino Real, San Bruno, CA
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Commercial Space Near Tech Hub
Contact for pricing

Commercial Space Near Tech Hub

Commercial space near YouTube, Google, and @WalmartLabs offices.

851 Cherry Ave, San Bruno, CA 94066
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Based on your search, we've compiled 25 Potential Opportunities for your consideration. Besides 12 Active listings in San Bruno, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 9 Properties for Sales.

Explore Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Retail Space in Millbrae, CA
$1,700 /Mo
9,040 SF

Retail Space in Millbrae, CA

Retail space available for lease in Millbrae, California.

1641 El Camino Real, Millbrae, CA 94030
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Two-Story Office Space Available
Contact for pricing
1,310 SF

Two-Story Office Space Available

Office space for rent in Belmont with flexible lease terms.

1625 El Camino Real, Millbrae, CA
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Retail Space in South San Francisco
Contact for pricing
1,628 SF

Retail Space in South San Francisco

Retail space in well-located neighborhood center with highway access.

128 Brentwood Dr, South San Francisco, CA
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Industrial Space Near Caltrain, SFO
$1.50 SF/Yr
6,644 SF

Industrial Space Near Caltrain, SFO

Industrial space near Caltrain and SFO with one roll-up door.

1098 San Mateo Ave, South San Francisco, CA
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Explore Similar Spaces for Sale in San Bruno, CA

Consider Similar Space for Sale. We found 9 Spaces matching your search parameters.

Turnkey Restaurant in San Bruno
$395,000
2,000 SF

Turnkey Restaurant in San Bruno

Fully equipped Korean BBQ restaurant ready for operation.

Address not disclosed, San Bruno, CA 94066
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Mixed-Use Property in San Bruno
$1,195,000
3,877 SF

Mixed-Use Property in San Bruno

Three-unit mixed-use property with residential flat and retail spaces.

521 San Mateo Avenue, San Bruno, CA 94066
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San Bruno Industrial Warehouse Opportunity
$1,250,000
2,500 SF

San Bruno Industrial Warehouse Opportunity

2,500 sq ft San Bruno warehouse for sale.

1141 San Mateo Avenue, San Bruno, CA 94066
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Industrial Building Near Transportation Hub
$995,000
2,500 SF

Industrial Building Near Transportation Hub

2,500 SF industrial building, available April 2026, near highways.

1125 San Mateo Ave, San Bruno, CA 94066
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San Bruno Retail Opportunity
$9,500,000
12,350 SF

San Bruno Retail Opportunity

85% leased retail property with strong national tenants.

1050 Admiral Ct, San Bruno, CA
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Established 7-Eleven Franchise Opportunity
$75,000
2,000 SF

Established 7-Eleven Franchise Opportunity

Thriving 7-Eleven franchise in high-traffic San Bruno location.

2020 Rollingwood Drive, San Bruno, CA 94066
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Transit-Oriented Corner Lot For Sale
$3,995,000
4,036 SF

Transit-Oriented Corner Lot For Sale

Commercial land for sale near San Bruno Caltrain Station.

265 San Bruno Ave E, San Bruno, CA
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San Bruno Commercial Buildings ForSale
$3,995,000
6,520 SF

San Bruno Commercial Buildings ForSale

Commercial buildings with development potential near San Bruno Caltrain Station.

820 San Mateo Ave, San Bruno, CA
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Established 7-Eleven Franchise Opportunity
$75,000
2,030 SF

Established 7-Eleven Franchise Opportunity

Thriving 7-Eleven franchise in high-traffic San Bruno location.

2020 Rollingwood Dr, San Bruno, CA 94066
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San Bruno, CA Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in San Bruno, CA with 12 listings featured on our commercial real estate exchange. The current inventory includes 376,663,320 square feet of properties with an estimated lease value of $42 SF/Yr.

Estimated lease rates for Commercial real estate in San Bruno, CA begin at $2 SF/Yr, with an average of $14 SF/Yr and extend to $35 SF/Yr.
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