San Bruno, CA Commercial Real Estate for Lease

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Professional Medical Office Building
Updated: Jan 27
Professional Medical Office Building

1001 Sneath Lane, San Bruno, CA 94066

$45 SF/Yr
32,658 sqft
Prime location in San Bruno, San Mateo County with easy access to HWY 101, 280, and 380.
Professional medical office building suitable for private medical practices.
High‑end medical buildout already in place.
Abundant on‑site parking available.
Large reception and waiting area.
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Divisible Medical Office Suites
Updated: Jun 8
Divisible Medical Office Suites

931 San Bruno Ave W, San Bruno, CA 94066

Contact for pricing
1,782 sqft
Two office suites totaling 3,141 SF, divisible into 1,359 SF and 1,782 SF suites
Build‑to‑suit dental office improvements available
Suite layout includes open area, private offices, kitchen, and restroom
2 large monument signs on San Bruno Ave
Parking available: off‑street and on‑street neighborhood parking
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San Bruno Commercial Space Available
San Bruno Commercial Space Available

1142-1178 Cherry Ave, San Bruno, CA 94066

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5,135 sqft

Commercial space available for rent in San Bruno, CA.

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Retail Space Near Tech Hub
Retail Space Near Tech Hub

899 Cherry Ave, San Bruno, CA

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4,003 sqft

Retail space available near YouTube, Google, and Walmart Labs.

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Industrial Flex Space Near Transit
Industrial Flex Space Near Transit

925 San Mateo Avenue, San Bruno, CA 94066

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9,542 sqft

Four-building industrial flex space near Caltrain and BART stations.

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San Bruno Flex Space Available
San Bruno Flex Space Available

1051-1099 Sneath Ln, San Bruno, CA

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3,600 sqft

Flex space featuring 1,000 SF office and grade-level loading.

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San Bruno Office Space Available
San Bruno Office Space Available

851 Traeger Avenue, San Bruno, CA 94066

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10,102 sqft

Office space available for lease in San Bruno, California.

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Retail Space in San Bruno
Retail Space in San Bruno

851 Cherry Avenue, San Bruno, CA 94066

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Established shopping center anchored by Mollie Stone’s in San Bruno.

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Class A Office Space Available
Class A Office Space Available

801 Traeger Ave, San Bruno, CA

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1,512 sqft

Improved Class A office space near SFO and public transit.

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San Bruno Retail Space Available
San Bruno Retail Space Available

855-875 El Camino Real, San Bruno, CA

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9,590 sqft

9,590 SF retail space for rent in San Bruno.

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San Bruno Office Space Available
San Bruno Office Space Available

801-851 Traeger Avenue, San Bruno, CA 94066

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Office space for rent with shuttle to transit stations.

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Commercial Space Near Tech Hub
Commercial Space Near Tech Hub

851 Cherry Ave, San Bruno, CA 94066

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Commercial space near YouTube, Google, and @WalmartLabs offices.

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Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 12 Active listings in San Bruno, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 8 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Retail Storefront with Major Frontage
Retail Storefront with Major Frontage

249 Kenwood Way, South San Francisco, CA 94080

Contact for pricing
1,628 sqft

Ground-level retail space in a neighborhood center with El Camino Real frontage and established anchors.

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South San Francisco Warehouse Space
South San Francisco Warehouse Space

1477 Huntington Avenue, South San Francisco, CA 94080

$35,000 SF/Yr
87,120 sqft

87,120 sqft warehouse available for lease in South San Francisco.

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Retail Space in South San Francisco
Retail Space in South San Francisco

128 Brentwood Dr, South San Francisco, CA

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1,628 sqft

Retail space in well-located neighborhood center with highway access.

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Industrial Space Near Caltrain, SFO
Industrial Space Near Caltrain, SFO

1098 San Mateo Ave, South San Francisco, CA

Contact for pricing
6,644 sqft

Industrial space near Caltrain and SFO with one roll-up door.

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Similar Spaces for Sale in San Bruno, CA

Consider Similar Space for Sale. We found 8 Spaces matching your search parameters.

Turnkey Korean BBQ Restaurant
Turnkey Korean BBQ Restaurant

Address not disclosed, San Bruno, CA 94066

$395,000
0.16 AC lot

Turnkey Korean BBQ restaurant with equipped kitchen, dining capacity up to 77, and beer and wine license.

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San Bruno Industrial Warehouse Opportunity
San Bruno Industrial Warehouse Opportunity

1141 San Mateo Avenue, San Bruno, CA 94066

$1,250,000
2,500 sqft

2,500 sq ft San Bruno warehouse for sale.

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Industrial Building Near Transportation Hub
Industrial Building Near Transportation Hub

1125 San Mateo Ave, San Bruno, CA 94066

$995,000
2,500 sqft 0.06 AC lot

2,500 SF industrial building, available April 2026, near highways.

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San Bruno Commercial Property For Sale
San Bruno Commercial Property For Sale

1610 El Camino Real, San Bruno, CA 94066

$395,000
2,000 sqft

Commercial property available in San Mateo County.

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San Bruno Retail Opportunity
San Bruno Retail Opportunity

1050 Admiral Ct, San Bruno, CA

$9,500,000
12,350 sqft 1.02 AC lot

85% leased retail property with strong national tenants.

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Transit-Oriented Corner Lot For Sale
Transit-Oriented Corner Lot For Sale

265 San Bruno Ave E, San Bruno, CA

$3,995,000
4,036 sqft 0.17 AC lot

Commercial land for sale near San Bruno Caltrain Station.

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San Bruno Commercial Buildings ForSale
San Bruno Commercial Buildings ForSale

820 San Mateo Ave, San Bruno, CA

$3,995,000
6,520 sqft 0.26 AC lot

Commercial buildings with development potential near San Bruno Caltrain Station.

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Established 7-Eleven Franchise Opportunity
Established 7-Eleven Franchise Opportunity

2020 Rollingwood Dr, San Bruno, CA 94066

$75,000
2,030 sqft

Thriving 7-Eleven franchise in high-traffic San Bruno location.

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San Bruno, CA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in San Bruno, CA with 12 listings featured on our commercial real estate exchange. The current inventory includes 43,712 square feet of properties with an estimated lease value of $52.15 SF/Yr.

Estimated lease rates for Commercial real estate in San Bruno, CA begin at $2.50 SF/Yr, with an average of $17.38 SF/Yr and extend to $45 SF/Yr.
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