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    San Bruno, CA
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    San Bruno, CA Commercial Real Estate for Lease

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    South San Francisco, CA Belmont, CA Millbrae, CA
    15 results
    CA, South San Francisco - Spaces Oyster Point
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    Spaces Clocktower
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    Professional Medical Office Building
    $45 SF/Yr
    32,658 SF

    Professional Medical Office Building

    1001 Sneath Lane, San Bruno, CA 94066

    Professional medical office building in a prime location with ample parking.

    • Prime location in San Bruno, San Mateo County with easy access to HWY 101, 280, and 380.
    • Professional medical office building suitable for private medical practices.
    • High‑end medical buildout already in place.
    • Abundant on‑site parking available.
    • Large reception and waiting area.
    Updated: Jan 27
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    Industrial Flex Space Near Transit
    $2 SF/Yr
    9,542 SF

    Industrial Flex Space Near Transit

    925 San Mateo Avenue, San Bruno, CA 94066

    Four-building industrial flex space near Caltrain and BART stations.

    • Excellent transportation access: Just 0.1 miles from Caltrain and 0.5 miles from BART San Bruno Station.
    • Substantial ±46,479 SF parcel.
    • Features 4 standalone buildings totaling ±9,542 SF.
    • Building 1 includes ±3,172 SF.
    • Building 4 includes ±2,442 SF.
    Updated: Nov 22, 2025
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    San Bruno Office Suites Available
    Contact for pricing
    3,141 SF

    San Bruno Office Suites Available

    Medical or general office suites available for rent.

    931 San Bruno Avenue West, San Bruno, CA 94066
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    Class A Office Space Available
    $4 SF/Yr
    1,512 SF

    Class A Office Space Available

    Improved Class A office space near SFO and public transit.

    801 Traeger Ave, San Bruno, CA
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    Retail Space in San Bruno
    Contact for pricing

    Retail Space in San Bruno

    Established shopping center anchored by Mollie Stone’s in San Bruno.

    851 Cherry Avenue, San Bruno, CA 94066
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    San Bruno Commercial Space Available
    Contact for pricing
    5,135 SF

    San Bruno Commercial Space Available

    Commercial space available for rent in San Bruno, CA.

    1142-1178 Cherry Ave, San Bruno, CA 94066
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    Prime Location Retail/Office Space
    $5,900/Mo
    2,000 SF

    Prime Location Retail/Office Space

    2000 SF retail/office space with ample parking.

    El Camino Real, San Bruno, CA 94066
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    San Bruno Office Space Available
    Contact for pricing

    San Bruno Office Space Available

    Office space for rent with shuttle to transit stations.

    801-851 Traeger Avenue, San Bruno, CA 94066
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    Retail Space Near Tech Hub
    Contact for pricing
    4,003 SF

    Retail Space Near Tech Hub

    Retail space available near YouTube, Google, and Walmart Labs.

    899 Cherry Ave, San Bruno, CA
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    San Bruno Office Space Available
    Contact for pricing
    10,102 SF

    San Bruno Office Space Available

    Office space available for lease in San Bruno, California.

    851 Traeger Avenue, San Bruno, CA 94066
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    San Bruno Flex Space Available
    $2 SF/Yr
    3,600 SF

    San Bruno Flex Space Available

    Flex space featuring 1,000 SF office and grade-level loading.

    1051-1099 Sneath Ln, San Bruno, CA
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    San Bruno Retail Space Available
    Contact for pricing
    9,590 SF

    San Bruno Retail Space Available

    9,590 SF retail space for rent in San Bruno.

    855-875 El Camino Real, San Bruno, CA
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    Commercial Space Near Tech Hub
    Contact for pricing

    Commercial Space Near Tech Hub

    Commercial space near YouTube, Google, and @WalmartLabs offices.

    851 Cherry Ave, San Bruno, CA 94066
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    Based on your search, we've compiled 30 Potential Opportunities for your consideration. Besides 15 Active listings in San Bruno, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 11 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    First-Floor Office Suite
    $1,700/Mo

    First-Floor Office Suite

    First-floor office suite with strong visibility and foot traffic in a convenient, transit-friendly location.

    1641 El Camino Real, Millbrae, 94030
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    Two-Story Office Space Available
    Contact for pricing
    1,310 SF

    Two-Story Office Space Available

    Office space for rent in Belmont with flexible lease terms.

    1625 El Camino Real, Millbrae, CA
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    South San Francisco Warehouse Space
    Contact for pricing
    25,141 SF

    South San Francisco Warehouse Space

    Industrial warehouse space available for lease in South San Francisco.

    340 Shaw Rd, South San Francisco, CA
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    Industrial Space Near Caltrain, SFO
    $1.50 SF/Yr
    6,644 SF

    Industrial Space Near Caltrain, SFO

    Industrial space near Caltrain and SFO with one roll-up door.

    1098 San Mateo Ave, South San Francisco, CA
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    Similar Spaces for Sale in San Bruno, CA

    Consider Similar Space for Sale. We found 11 Spaces matching your search parameters.

    San Bruno Commercial Building For Sale
    $998,000

    San Bruno Commercial Building For Sale

    Commercial building in the heart of the Central Business District.

    508 San Mateo Ave, San Bruno, CA 94066
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    Turnkey Restaurant in San Bruno
    $395,000
    2,000 SF

    Turnkey Restaurant in San Bruno

    Fully equipped Korean BBQ restaurant ready to operate.

    Address not disclosed, San Bruno, 94066
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    Mixed-Use Property in San Bruno
    $1,195,000
    3,877 SF

    Mixed-Use Property in San Bruno

    Three-unit mixed-use property with residential flat and retail spaces.

    521 San Mateo Avenue, San Bruno, CA 94066
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    Industrial Building Near Transportation Hub
    $995,000
    2,500 SF

    Industrial Building Near Transportation Hub

    2,500 SF industrial building, available April 2026, near highways.

    1125 San Mateo Ave, San Bruno, CA 94066
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    San Bruno Industrial Warehouse Opportunity
    $1,250,000
    2,500 SF

    San Bruno Industrial Warehouse Opportunity

    2,500 sq ft San Bruno warehouse for sale.

    1141 San Mateo Avenue, San Bruno, CA 94066
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    San Bruno Retail Opportunity
    $9,500,000
    12,350 SF

    San Bruno Retail Opportunity

    85% leased retail property with strong national tenants.

    1050 Admiral Ct, San Bruno, CA
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    San Bruno Commercial Property For Sale
    $395,000
    2,000 SF

    San Bruno Commercial Property For Sale

    Commercial property available in San Mateo County.

    1610 El Camino Real, San Bruno, CA 94066
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    Transit-Oriented Corner Lot For Sale
    $3,995,000
    4,036 SF

    Transit-Oriented Corner Lot For Sale

    Commercial land for sale near San Bruno Caltrain Station.

    265 San Bruno Ave E, San Bruno, CA
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    Established 7-Eleven Franchise Opportunity
    $75,000
    2,000 SF

    Established 7-Eleven Franchise Opportunity

    Thriving 7-Eleven franchise in high-traffic San Bruno location.

    2020 Rollingwood Drive, San Bruno, CA 94066
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    San Bruno, CA Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in San Bruno, CA with 15 listings featured on our commercial real estate exchange. The current inventory includes 49,312 square feet of properties with an estimated lease value of $89 SF/Yr.

    Estimated lease rates for Commercial real estate in San Bruno, CA begin at $2 SF/Yr, with an average of $17 SF/Yr and extend to $45 SF/Yr.
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    Most Searched ZIP Codes in San Bruno, CA

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