Daly City, CA Commercial real estate for Rent & Lease

Updated: Nov 22, 2025

Class A Lab/Office Space

2001 Junipero Serra Boulevard, Daly City, CA 94014

$6.25 SF/Yr

47,139 sqft

Class A laboratory and office building
Large, open floor plates ideal for modern lab design
Located right off I‑280
Premier visibility
Convenient access throughout the Bay Area

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Updated: Apr 20

Class A Laboratory Office Building

2001 Junipero Serra Blvd, Daly City, CA 94014

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12,118 sqft

GENESIS – Station is a nine‑story Class A laboratory and office building in Daly City, CA.
Retrofit multi‑tenant building with large, open floor plates and suites from about 19,800 to 48,000 RSF.
Robust laboratory infrastructure systems designed for lab‑and‑office use.
Convenient access: within walking distance to Daly City BART station for commuting from North, South, and East Bay.
Located along the I‑280 corridor with visibility, and surrounded by nearby retail shops and restaurants.

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Daly City Office Space Available

323 89th Street, Daly City, CA 94015

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6,189 sqft

Full floor office space with potential for multiple tenants.

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Retail Space in Active Location

6513-6543 Mission St, Daly City, CA

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2,663 sqft 1.38 AC lot

Corner lot retail space with high visibility and accessibility.

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Daly City Office Space

1655 Southgate Ave, #1st Floor, Daly City, CA 94015

$45 SF/Yr

Office space available for rent in Daly City, CA.

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Daly City Office Space Available

950 John Daly Boulevard, Daly City, CA 94015

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4,249 sqft

Office space for rent, walking distance to retail amenities.

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Multiple Office Suites For Lease

151 87th St, Daly City, CA 94015

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Four office suites are available, ranging from 180 to 600 square feet.

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Daly City Office Space Available

333 Gellert Blvd, Daly City, CA 94015

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Office suites available near Highway 280, BART, and SamTrans.

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Mixed-Use Space at Signalized Corner

2665 Geneva Ave, Daly City, CA 94014

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466 sqft

Restaurant space within a residential and retail project, with potential for office, medical, service, or other retail uses.

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Daly City Shopping Center Space

5-95 Southgate Ave, Daly City, CA

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2,606 sqft 0.86 AC lot

Retail space available in a large Daly City shopping center.

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Daly City Shopping Center Space

186-220 Southgate Ave, Daly City, CA

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1,275 sqft 1.72 AC lot

Retail space available in a 685,000 SF shopping center.

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High-Traffic Shopping Center Location

3 Serramonte Center, Daly City, CA 94015

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Conveniently located shopping center at I-280 and HWY 1.

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Based on your search, we've compiled 30 Potential Opportunities for your consideration. Besides 12 Active listings in Daly City, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 14 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Retail Suites at Manzanita Square

1557-1600 Holloway Ave, San Francisco, CA 94132

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1,172 sqft

Five retail suites occupy the first two floors of a 170-apartment student housing development.

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Warehouse Distribution Facility

6000 Midway Ave, Sacramento, CA 95828

$6.60 SF/Yr

Warehouse and distribution facility available for rent at 6000 Midway Ave in Sacramento.

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Retail Space on Geneva Avenue

974 Geneva Ave, San Francisco, CA

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972 sqft 0.06 AC lot

972 SF retail space with excellent visibility for rent.

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Warehouse with Yard and Office

1455-1475 Mission Rd, South San Francisco, CA

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4,000 sqft 0.47 AC lot

Warehouse with office, yard space, and auto zoning near transit.

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Similar Spaces for Sale in Daly City, CA

Consider Similar Space for Sale. We found 14 Spaces matching your search parameters.

Restaurant Space with Full Bar

6057 Mission Street, Daly City, CA 94014

$1,199,000

1,865 sqft 0.04 AC lot

Street-level premises include a commercial kitchen, two restrooms, and flexible storage or office areas.

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Mixed-Use Restaurant Property

65846582 Mission Street, Daly City, CA 94014

$895,000

2,554 sqft

Restaurant improvements, basement utility space, and two studio units support both owner occupancy and diversified income.

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Cafe Condo Near BART

137 D St, Daly City, CA 94014

$488,000

535 sqft 0.01 AC lot

Commercial condominium with an existing cafe and guest parking near the Colma BART Station.

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Daly City Industrial Space

3275 Geneva Avenue, Daly City, CA 94014

$3,452,380

14,200 sqft

14,200 SqFt industrial property available in Daly City, CA.

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Freestanding Retail Building Opportunity

6379 Mission St, Daly City, CA 94014

$850,000

Freestanding retail building with prominent Mission Street frontage and efficient layout on a 2,243 SF parcel.

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Specialty Commercial Property For Sale

29 Yacht Lane, Daly City, CA 94014

$459,000

1,760 sqft

Specialty-use commercial property offered for sale in Daly City, with access via Yacht Lane.

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Office Building with Post Office Tenant

6025 Mission Street, Daly City, CA 94014

$998,000

C-1 Light Commercial zoning and ADA-compliant restrooms support the building’s current commercial configuration.

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Vacant Land with High Visibility

2321 Geneva Avenue, Daly City, CA 94014

$8,000,000

0.44 AC lot

19,300 SF vacant land with mixed-use zoning.

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Mixed-Use Restaurant Property

6584-6582 Mission ST, Daly City, CA 94014

$895,000

Ground-floor restaurant space, basement support areas, and two studio units create a flexible owner-user or income-producing configuration.

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Distribution Center For Sale

6027 Mission Street, Daly City, CA 94014

$652,000

For-sale distribution center in San Mateo County with a listed size of 1,750.

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Gated Commercial Land

1110 Hillside Blvd, Daly City, CA 94014

$800,000

The paved, enclosed site has commercial zoning and residential use permit approval.

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Operating Equestrian Destination Property

2152 Olympic Way, Daly City, CA

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Fee parcel with hospitality pods, horse spaces, residence, retail, food and beverage, and equestrian programming.

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