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    Florence, SC Specialty Properties for Sale

    10 results
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    Commercial Property on S Cashua Drive
    $638,800
    13,801 SF

    Commercial Property on S Cashua Drive

    818 Delmae Dr, Florence, SC 29501

    Three buildings on three lots near Walmart in Florence, SC.

    • Three combined lots on S Cashua Drive, near Walmart.
    • Includes three buildings: two houses, a large garage, and a renovated tobacco barn. One building currently operates as a day care center.
    • Three separate tax map ID numbers.
    • Includes "Bathroom 1" and "Bathroom 2".
    • One house built in 1962.
    Updated: Dec 17, 2025
    View details
    McLeod Physician Associates For Sale
    Contact for pricing
    2,666 SF

    McLeod Physician Associates For Sale

    1540 American Dr, Florence, SC 29505

    2,666 SF medical office in Florence, SC for sale.

    • Secure Investment
    • Triple Net (NNN) Lease – Landlord Has Limited Responsibilities
    • Tenant Recently Extended Lease For an Additional 5 Years, showing long‑term commitment to the site
    • Located at 1540 American Drive in Florence, SC
    • 2,666 SF McLeod Physician Associates
    View details
    Florence Retail Investment Opportunity
    $400,000
    3,375 SF

    Florence Retail Investment Opportunity

    High-traffic location, 3 buildings, .82 acres

    710 Barringer St, Florence, SC 29501
    View details
    Florence Retail Investment Opportunity
    $200,000
    1,520 SF

    Florence Retail Investment Opportunity

    1,520 SF Commercial Building, $200,000

    702 Barringer St, Florence, SC 29501
    View details
    Florence Retail Investment Opportunity
    $200,000
    1,350 SF

    Florence Retail Investment Opportunity

    1,350 SF Retail Building, High Traffic Area

    726 Barringer St, Florence, SC 29501
    View details
    Florence Commercial Land Opportunity
    $520,000
    3,900 SF

    Florence Commercial Land Opportunity

    Prime 3,900 SF lot, $520,000

    181 Palmetto St, Florence, SC 29506
    View details
    Prime Florence SC Acreage
    $200,000
    12.00 Acres

    Prime Florence SC Acreage

    12 Acres, Hwy 301 & 76 Frontage

    301 And 76, Florence, SC 29501
    View details
    Prime Florence Commercial Land
    $50,000
    0.18 Acres

    Prime Florence Commercial Land

    0.18-Acre Lot, Zoned R-5A

    0 Tbd National Cemetery Rd, Florence, SC 29506
    View details
    Florence Commercial Building
    $262,500
    0.26 Acres

    Florence Commercial Building

    Versatile Office Building, High Traffic Area

    603 Palmetto St, Florence, SC 29501-4301
    View details
    Florence Commercial Corner Lot
    $125,000
    0.10 Acres

    Florence Commercial Corner Lot

    High-traffic location, prime development.

    360 Dargan St, Florence, SC 29501
    View details
    Based on your search, we've compiled 53 Potential Opportunities for your consideration. Besides 10 Active listings in Florence, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 38 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Versatile Land Tract in Hartsville
    $222,900
    27.54 Acres

    Versatile Land Tract in Hartsville

    27.54-acre tract with timber, open field, and pecan orchard.

    East Carolina Ave, Hartsville, SC 29550
    View details
    Hartsville Commercial Property for Sale
    $160,000
    3,300 SF

    Hartsville Commercial Property for Sale

    Commercial property in Hartsville, SC, offering 3,300 square feet.

    620 Pool St, Hartsville, SC 29550
    View details
    Dillon, SC Commercial Property
    $600,000
    4,500 SF

    Dillon, SC Commercial Property

    Turn-key Dry Cleaners, High-Traffic Location

    100 Calhoun St, Dillon, SC 29536
    View details
    Commercial Property in Historic District
    $35,000
    4,200 SF

    Commercial Property in Historic District

    Commercial property for sale in Dillon's historic district.

    224 E Main St, Dillon, SC 29536
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Florence Commercial Lot For Sale
    $1,500,000
    4.02 Acres

    Florence Commercial Lot For Sale

    4.02 acre mixed-use lot with high visibility in Florence, SC.

    1714 2Nd Loop Rd, Florence, SC 29501
    View details

    Explore Off-Market Properties in Florence, SC

    Consider similar Off-Market properties in Florence, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    720 Coit St

    720 Coit St

    Land • 3,000 SF
    Value Estimation by Request
    720 Coit St, Florence, SC 29501
    View details
    2421 Vance Dr

    2421 Vance Dr

    DAY CARE, PRE-SCHOOL • 5,220 SF
    Value Estimation by Request
    2421 Vance Dr, Florence, SC 29505-6161
    View details
    181 Palmetto St

    181 Palmetto St

    DAY CARE, PRE-SCHOOL • 3,900 SF
    Value Estimation by Request
    181 Palmetto St, Florence, SC 29506-2580
    View details
    1310 Cashua Dr

    1310 Cashua Dr

    VETERINARY, ANIMAL HOSPITAL • 8,227 SF
    Value Estimation by Request
    1310 Cashua Dr, Florence, SC 29501-6321
    View details
    107 Laurel St

    107 Laurel St

    DAY CARE, PRE-SCHOOL • 1,470 SF
    Value Estimation by Request
    107 Laurel St, Florence, SC 29501-5216
    View details
    2230 Jody Rd

    2230 Jody Rd

    VETERINARY, ANIMAL HOSPITAL • 4,160 SF
    Value Estimation by Request
    2230 Jody Rd, Florence, SC 29501-2046
    View details
    1617 2nd Loop Rd

    1617 2nd Loop Rd

    DAY CARE, PRE-SCHOOL • 5,872 SF
    Value Estimation by Request
    1617 2nd Loop Rd, Florence, SC 29505-2805
    View details
    3501 Pne Needles Rd

    3501 Pne Needles Rd

    DAY CARE, PRE-SCHOOL • 5,000 SF
    Value Estimation by Request
    3501 Pne Needles Rd, Florence, SC 29501-8534
    View details
    930 Sumter St

    930 Sumter St

    FUNERAL HOME • 2,800 SF
    Value Estimation by Request
    930 Sumter St, Florence, SC 29501-2154
    View details
    1100 Palmetto St

    1100 Palmetto St

    DAY CARE, PRE-SCHOOL • 1,956 SF
    Value Estimation by Request
    1100 Palmetto St, Florence, SC 29506-2944
    View details
    Tbd National Cemetery Rd

    Tbd National Cemetery Rd

    Land • 0.18 Acres
    Value Estimation by Request
    0 Tbd National Cemetery Rd, Florence, SC 29506
    View details
    400 Dargan St

    400 Dargan St

    FUNERAL HOME • 11,900 SF
    Value Estimation by Request
    400 Dargan St, Florence, SC 29506-2540
    View details
    815 2nd Loop Rd

    815 2nd Loop Rd

    VETERINARY, ANIMAL HOSPITAL • 2,325 SF
    Value Estimation by Request
    815 2nd Loop Rd, Florence, SC 29505-2826
    View details
    Enterprise Dr

    Enterprise Dr

    DAY CARE, PRE-SCHOOL • 4,178 SF
    Value Estimation by Request
    Enterprise Dr, Florence, SC 29501
    View details

    Florence, SC Specialty Properties Investment Opportunities Market Analysis

    Explore 48 specialty properties for sale in Florence, SC, showcased through 10 active listings on our real estate platform. These investment opportunities span a total of 1,279,387 square feet of properties for sale, with an estimated market value of $10,031,300.

    Sale prices for properties in Florence, SC start at $50,000, averaging $385,819, and reaching up to $890,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Specialty properties for Sale Near Florence, SC

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    Most Searched ZIP Codes in Florence, SC

    • 29501
    • 29506
    • 29505

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