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Florence, SC Retail Space for Sale

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Prime Retail Investment Opportunity
$550,000
2,304 SF

Prime Retail Investment Opportunity

225 W Lucas St, Florence, SC 29501

Two-unit property with high visibility and income potential in Florence.

  • Prime commercial investment opportunity on the high‑traffic US‑52/Lucas Street Corridor (24,700 vehicles daily).
  • Versatile two‑unit property with dual revenue stream potential (convenience/restaurant + potential liquor store).
  • Front unit equipped for restaurant conversion: natural gas, commercial hood vent, take‑out window, seating area.
  • Rear unit has permit application underway for liquor store operations.
  • Located in Florence City Council’s targeted redevelopment zone for the US‑52 Corridor.
Last Update: Jul 24
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Prime Commercial Investment Opportunity
$550,000
2,304 SF

Prime Commercial Investment Opportunity

225 W Lucas St, Florence, SC 29501

Two-unit property with high visibility and income potential.

  • Prime commercial investment opportunity in a high‑traffic location (24,700 vehicles daily) along the US‑52/Lucas Street Corridor.
  • Versatile two‑unit property with dual revenue stream potential; rear unit has permit application underway for liquor store operations.
  • Front unit (225 W Lucas St) is equipped for restaurant conversion with natural gas access, commercial hood vent, and take‑out window.
  • Located in Florence City Council’s targeted redevelopment zone for the US‑52 Corridor, with planned infrastructure improvements.
  • Outstanding visibility and accessibility, located minutes from I‑95 and surrounded by over 5,000 hotel rooms.
Last Update: Jul 24
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Florence, SC Medical Facility
$4,092,000
17,174 SF

Florence, SC Medical Facility

Corporate-leased medical building, high NOI.
1933 2Nd Loop Rd, Florence, SC 29501
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Retail Property in Prime Location
$1,389,000
4,160 SF

Retail Property in Prime Location

Single-tenant net-leased The Vitamin Shoppe in Florence, SC.
2590 David H Mcleod Blvd, Florence, SC 29501
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Based on your search, we've compiled 158 Potential Opportunities for your consideration. Besides 4 Active listings in Florence, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 150 Off-Market properties to explore as potential leads

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Downtown Marion Retail Opportunity
$250,000
2,662 SF

Downtown Marion Retail Opportunity

Commercial retail space in downtown Marion with income potential.
516 N Main St, Marion, SC 29571
View details
Downtown Marion Retail/Office Opportunity
$275,000
4,000 SF

Downtown Marion Retail/Office Opportunity

Former bank building in revitalized downtown Marion historic district.
507 N Main St, Marion, SC 29571
View details
Strip Retail Space on Main
$125,000
2,580 SF

Strip Retail Space on Main

Three-unit retail space with accessible parking and nearby amenities.
245 E Main St, Kingstree, SC 29556
View details
New
Kingstree Retail Building For Sale
$349,000
10,043 SF

Kingstree Retail Building For Sale

10,043 SF retail building in growing downtown Kingstree, SC.
134 Hampton Ave, Kingstree, SC 29556
View details

Explore Off-Market Properties in Florence, SC

Consider similar Off-Market properties in Florence, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

130 Dargan St

130 Dargan St

Individual retail properties • 6,520 SF
Value Estimation by Request
130 Dargan St, Florence, SC 29506
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1933 2Nd Loop Rd

1933 2Nd Loop Rd

Individual retail properties • 17,174 SF
Value Estimation by Request
1933 2Nd Loop Rd, Florence, SC 29501
View details
101 Evans St

101 Evans St

RETAIL STORES (PERSONAL SERVICES) • 22,242 SF
Value Estimation by Request
101 Evans St, Florence, SC 29501-3425
View details
167 Dargan St

167 Dargan St

RETAIL STORES (PERSONAL SERVICES) • 1,722 SF
Value Estimation by Request
167 Dargan St, Florence, SC 29506-2501
View details
155 Dargan St

155 Dargan St

RETAIL STORES (PERSONAL SERVICES) • 3,920 SF
Value Estimation by Request
155 Dargan St, Florence, SC 29506-2578
View details
1508th N Cashua Dr

1508th N Cashua Dr

RETAIL STORES (PERSONAL SERVICES) • 11,000 SF
Value Estimation by Request
1508th N Cashua Dr, Florence, SC 29501-6970
View details
1359 Irby St

1359 Irby St

RETAIL STORES (PERSONAL SERVICES) • 2,080 SF
Value Estimation by Request
1359 Irby St, Florence, SC 29505-2757
View details
3376 Palmetto St

3376 Palmetto St

RETAIL STORES (PERSONAL SERVICES) • 7,416 SF
Value Estimation
$680,000
3376 Palmetto St, Florence, SC 29501-5942
View details
1933 Hoffmeyer Rd

1933 Hoffmeyer Rd

RETAIL STORES (PERSONAL SERVICES) • 11,700 SF
Value Estimation
$480,000
1933 Hoffmeyer Rd, Florence, SC 29501-4011
View details
631 Irby St

631 Irby St

RETAIL STORES (PERSONAL SERVICES) • 1,110 SF
Value Estimation by Request
631 Irby St, Florence, SC 29501-5211
View details
1551 2nd Loop Rd

1551 2nd Loop Rd

RETAIL STORES (PERSONAL SERVICES) • 15,400 SF
Value Estimation by Request
1551 2nd Loop Rd, Florence, SC 29505-2803
View details
1227 Cashua Dr

1227 Cashua Dr

RETAIL STORES (PERSONAL SERVICES) • 1,800 SF
Value Estimation by Request
1227 Cashua Dr, Florence, SC 29501-6937
View details
1901 Palmetto St

1901 Palmetto St

RETAIL STORES (PERSONAL SERVICES) • 3,060 SF
Value Estimation by Request
1901 Palmetto St, Florence, SC 29501-3916
View details
1125 Evans St

1125 Evans St

RETAIL STORES (PERSONAL SERVICES) • 23,232 SF
Value Estimation by Request
1125 Evans St, Florence, SC 29501-3319
View details
3979 Palmetto St

3979 Palmetto St

RETAIL STORES (PERSONAL SERVICES) • 3,560 SF
Value Estimation by Request
3979 Palmetto St, Florence, SC 29501-8105
View details
2618 2nd Loop Rd

2618 2nd Loop Rd

RETAIL STORES (PERSONAL SERVICES) • 2,400 SF
Value Estimation
$205,000
2618 2nd Loop Rd, Florence, SC 29501-5431
View details
345 Ebenezer Rd

345 Ebenezer Rd

RETAIL STORES (PERSONAL SERVICES) • 1,200 SF
Value Estimation
$355,000
345 Ebenezer Rd, Florence, SC 29501-7906
View details
120 Sebrell St

120 Sebrell St

RETAIL STORES (PERSONAL SERVICES) • 12,500 SF
Value Estimation by Request
120 Sebrell St, Florence, SC 29505-2769
View details
960 Pamplico Hwy

960 Pamplico Hwy

RETAIL STORES (PERSONAL SERVICES) • 22,265 SF
Value Estimation by Request
960 Pamplico Hwy, Florence, SC 29505-6244
View details
2210 Irby St

2210 Irby St

RETAIL STORES (PERSONAL SERVICES) • 6,895 SF
Value Estimation by Request
2210 Irby St, Florence, SC 29505-3423
View details

Florence, SC Retail Space Investment Opportunities Market Analysis

Explore 152 retail space for sale in Florence, SC, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 4,573,610 square feet of properties for sale, with an estimated market value of $73,147,000.

Prices for retail space in Florence, SC start at $60,000, averaging $988,472, and reaching up to $13,230,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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