For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Retail
1
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
  • Hospitality
  • Sports & Entertainment
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

Florence, SC Retail Properties & Spaces for Lease

18 results
List
Map
Versatile Commercial Space in Florence
$5,000 / Mo
11,390 SF

Versatile Commercial Space in Florence

374 Darlington St, Florence, SC 29501

Commercial property with bay doors, ideal for automotive or warehouse.

  • Prime Downtown Florence, SC location
  • Multiple bay doors for easy access and operations
  • Versatile space suitable for automotive, warehouse, or service‑related businesses
  • Abundant open space for vehicles, equipment, or flexible use
  • Dedicated office space for administrative functions
Updated: Oct 11, 2025
View details
Restaurant Space Near I-95
$7,680 / Mo
4,190 SF

Restaurant Space Near I-95

3751 W Palmetto St, Florence, SC 29501

Restaurant space for lease with high visibility and traffic.

  • High traffic location with 36,300 vehicles daily on I‑95 and 17,800 vehicles daily on US‑76.
  • Excellent visibility and accessibility with copious road frontage, two driveway entrances, and ample parking.
  • Located off I‑95 Exit 157.
  • Surrounded by established national brands (McDonald’s, Waffle House, etc.).
  • 4,190 SF restaurant space available for lease.
Updated: Sep 2, 2025
View details
Restaurant Space Near I-95
$7,680 / Mo
4,190 SF

Restaurant Space Near I-95

Restaurant space for lease with high visibility and traffic.

3751 W Palmetto St, Florence, SC 29501
View details
Retail Space in Florence, SC
Contact for pricing

Retail Space in Florence, SC

Located at a busy intersection with high visibility and access.

S Ebenezer Rd, Florence, SC 29501
View details
Retail Space in Regional Destination
Contact for pricing
14,800 SF

Retail Space in Regional Destination

Retail space available in premier shopping center, built in 2015.

112-120 Woody Jones Blvd, Florence, SC 29501
View details
Retail Space in Florence, SC
Contact for pricing
8,000 SF

Retail Space in Florence, SC

8,000 SF retail space available for lease.

2600 David H Mcleod Blvd, Florence, SC 29501
View details
Retail Space in Regional Destination
Contact for pricing
2,400 SF

Retail Space in Regional Destination

Retail spaces available in premier shopping destination, built in 2015.

104 Woody Jones Blvd, Florence, SC 29501
View details
Florence Warehouse in West End
Contact for pricing

Florence Warehouse in West End

Warehouse in Florence's West End District, near major retailers.

2295 Hoffmeyer Rd, Florence, SC 29501
View details
Renovated Retail Space on US-52
Contact for pricing

Renovated Retail Space on US-52

Anchor suite in renovated shopping center with high visibility.

1611 S Irby St, Florence, SC 29505
View details
Downtown Florence Mixed-Use Space
Contact for pricing

Downtown Florence Mixed-Use Space

Prime mixed-use space in Downtown Florence Historic District.

127 W Evans St, Florence, SC 29501
View details
Retail Space at Claussen Shops
Contact for pricing

Retail Space at Claussen Shops

Grocery-anchored retail space for lease with ample parking.

2332 Pamplico Hwy, Florence, SC 29505
View details
Retail Space in Regional Destination
Contact for pricing
4,475 SF

Retail Space in Regional Destination

Retail spaces available in premier shopping destination near major highways.

110 Woody Jones Blvd, Florence, SC 29501
View details
Retail Space in Five Points
Contact for pricing

Retail Space in Five Points

End-cap retail space in a high-traffic area for lease.

1939 Hoffmeyer Rd, Florence, SC 29501
View details
Retail Outparcel in High-Traffic Area
Contact for pricing

Retail Outparcel in High-Traffic Area

Outparcel for ground lease or build-to-suit in Florence, SC.

500 2Nd Loop Rd, Florence, SC 29505
View details
Established Commercial Complex on Second Loop
Contact for pricing

Established Commercial Complex on Second Loop

Multi-tenant commercial complex with high visibility and convenient access.

1800 2Nd Loop Rd, Florence, SC 29501
View details
Prime Outparcel Opportunities in Florence
Contact for pricing

Prime Outparcel Opportunities in Florence

Outparcels available at I-95 interchange, ideal for hotels, restaurants.

2939 N Williston Rd, Florence, SC 29506
View details
Retail Space in Florence Mall
Contact for pricing

Retail Space in Florence Mall

Prime retail space in regional shopping center, Florence, South Carolina.

1945 W Palmetto St, Florence, SC 29501
View details
Based on your search, we've compiled 51 Potential Opportunities for your consideration. Besides 18 Active listings in Florence, SC, we suggest exploring alternatives. Similar 33 Properties for Sales.

Explore Similar Spaces for Sale in Florence, SC

Consider Similar Space for Sale. We found 7 Spaces in Nearby Locations matching your search parameters.

Industrial Building in Florence, SC
$550,000
67,518 SF

Industrial Building in Florence, SC

Standalone industrial building suitable for various commercial and industrial uses.

121 Lawson St, Florence, SC 29501
View details
Historic Downtown Florence Commercial Building
$2,700,000
16,304 SF

Historic Downtown Florence Commercial Building

16,000 SF historic building in thriving downtown Florence.

248-260 W Evans St, Florence, SC 29501
View details
Established Auto Body Business For Sale
$1,305,000
4,125 SF

Established Auto Body Business For Sale

Turn-key auto body business with equipment, client roster, and real estate.

803 Ranch Rd, Florence, SC 29506
View details
Industrial Buildings with Power & Access
$199,000
40,000 SF

Industrial Buildings with Power & Access

Two industrial buildings ideal for fabrication, automotive, or storage.

120 N Guerry St, Florence, SC 29501
View details
Florence Commercial Building on Evans
$79,000
1,200 SF

Florence Commercial Building on Evans

Standalone building on Evans Street with redevelopment potential.

617 W Evans St, Florence, SC 29501
View details
Turnkey Fish Market Opportunity
$250,900
2,499 SF

Turnkey Fish Market Opportunity

Profitable, equipped fish market for sale in Florence, SC.

1401 W Darlington St, Florence, SC 29501
View details
Versatile Commercial Building on Acreage
$500,000

Versatile Commercial Building on Acreage

Single-tenant building with showroom, warehouse, and fenced yard.

511 Irby St, Florence, SC 29501
View details

Florence, SC Retail properties & Spaces Leasing Opportunities Market Analysis

Explore Retail properties & Spaces leasing options in Florence, SC with 18 listings featured on our commercial real estate exchange. The current inventory includes 5,295,066,480 square feet of properties with an estimated lease value of $198 SF/Yr.

Estimated lease rates for Retail properties & Spaces in Florence, SC begin at $5 SF/Yr, with an average of $28 SF/Yr and extend to $90 SF/Yr.
List
Map