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Florence, SC Retail Properties for Sale

18 results
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Established Auto Body Business For Sale
$1,305,000
4,125 SF

Established Auto Body Business For Sale

803 Ranch Rd, Florence, SC 29506

Turn-key auto body business with real estate in Florence, SC.

  • Established auto body business operating for over 30 years.
  • Sale includes all equipment, signage, business name, phone number, and client roster.
  • Turn‑key operation ideal for investor or owner‑operator.
  • High‑visibility location with long‑standing customer base.
  • Includes real estate and profitable business value.
Updated: Aug 3, 2025
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Pamplico Highway Commercial Opportunity
$229,900
0.80 Acres

Pamplico Highway Commercial Opportunity

1424 Pamplico Hwy, Florence, SC 29505

Commercial lot on heavily traveled Pamplico Highway with multiple driveways.

  • High‑traffic location on Pamplico Highway
  • Four driveways providing easy access
  • Suitable for retail or commercial development
  • Existing house usable as an office
  • Road frontage
Updated: Aug 14, 2025
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Walgreens Investment Opportunity
$4,750,000
14,500 SF

Walgreens Investment Opportunity

NNN Leased Walgreens in Florence, SC

2498 2nd Loop Rd, Florence, SC 29501
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Florence Retail Investment Opportunity
$400,000
3,375 SF

Florence Retail Investment Opportunity

High-traffic location, 3 buildings, .82 acres

710 Barringer St, Florence, SC 29501
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Florence Mixed-Use Investment Opportunity
$500,000
1.38 Acres

Florence Mixed-Use Investment Opportunity

High-traffic SC-327 Retail & Restaurant Space

0 Sc-327, Florence, SC 29506
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Florence, SC Medical Facility
$4,092,000
17,174 SF

Florence, SC Medical Facility

Corporate-leased medical building, high NOI.

1933 2Nd Loop Rd, Florence, SC 29501
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Downtown Florence Restaurant - Prime Location
$3,400,000
6,000 SF

Downtown Florence Restaurant - Prime Location

Thriving Restaurant & Income Property

135 Palmetto St, Florence, SC 29506
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Florence Restaurant - Prime Location
$739,000
4,682 SF

Florence Restaurant - Prime Location

Established Restaurant, 4,682 SF, 1.48 Acres

1513 Pamplico Hwy, Florence, SC 29505
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Florence Retail Investment Opportunity
$200,000
1,520 SF

Florence Retail Investment Opportunity

1,520 SF Commercial Building, $200,000

702 Barringer St, Florence, SC 29501
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Florence, SC Hwy 76 Commercial Land
$1,750,000
10.55 Acres

Florence, SC Hwy 76 Commercial Land

10.55 Acres, Mixed-Use Development Potential

0 Us-76, Florence, SC 29506
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Florence Retail Investment Opportunity
$200,000
1,350 SF

Florence Retail Investment Opportunity

1,350 SF Retail Building, High Traffic Area

726 Barringer St, Florence, SC 29501
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Hwy 327 Mixed-Use Investment Opportunity
$500,000
1.38 Acres

Hwy 327 Mixed-Use Investment Opportunity

High-traffic Florence, SC retail center. Excellent visibility.

0 Sc-327, Florence, SC 29506
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Wendy's Restaurant For Sale
Contact for pricing
2,058 SF

Wendy's Restaurant For Sale

Wendy’s in Florence, South Carolina, leased for 20 years.

4010 E Palmetto St, Florence, SC 29501
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Wendy’s Restaurant in Florence, SC
Contact for pricing
2,202 SF

Wendy’s Restaurant in Florence, SC

Wendy’s restaurant for sale on high-traffic retail corridor.

624 S Irby St, Florence, SC 29501
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Historic Mixed-Use Building in Florence
$3,000,000
13 SF

Historic Mixed-Use Building in Florence

16,000 sq ft historic building in Downtown Florence for sale.

248 W Evans St Florence, Florence, SC 29501
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Retail Property in Prime Location
$1,389,000
4,160 SF

Retail Property in Prime Location

Single-tenant net-leased The Vitamin Shoppe in Florence, SC.

2590 David H Mcleod Blvd, Florence, SC 29501
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Retail Property Near Major Intersections
Contact for pricing
38,000 SF

Retail Property Near Major Intersections

Retail property with high visibility and easy access.

2640 W Palmetto St, Florence, SC 29501
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Former Convenience Store Investment Property
$125,000
2,400 SF

Former Convenience Store Investment Property

Fixer-upper retail property with 150' frontage, great investment potential.

1134 E Howe Springs Rd, Florence, SC 29505
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Based on your search, we've compiled Potential Opportunities for your consideration. Besides 18 Active Listings in Florence, SC, we suggest to view alternatives - similar 984 Off-Market properties to explore as potential leads.

Explore Off-Market Properties in Florence, SC

Consider similar Off-Market properties in Florence, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

Sc-327

Sc-327

Individual retail properties • 1.38 Acres
Value Estimation by Request
0 Sc-327, Florence, SC 29506
View details
130 Dargan St

130 Dargan St

Individual retail properties • 6,520 SF
Value Estimation by Request
130 Dargan St, Florence, SC 29506
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Us-76

Us-76

Lifestyle centers • 10.55 Acres
Value Estimation by Request
0 Us-76, Florence, SC 29506
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2298 Irby St

2298 Irby St

Restaurants • 3,040 SF
Value Estimation by Request
2298 Irby St, Florence, SC 29505
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Sc-327

Sc-327

Lifestyle centers • 1.38 Acres
Value Estimation by Request
0 Sc-327, Florence, SC 29506
View details
1933 2Nd Loop Rd

1933 2Nd Loop Rd

Individual retail properties • 17,174 SF
Value Estimation by Request
1933 2Nd Loop Rd, Florence, SC 29501
View details

Florence, SC Retail Properties Investment Opportunities Market Analysis

Explore 999 retail properties for sale in Florence, SC, showcased through 18 active listings on our real estate platform. These investment opportunities span a total of 62,005,802 square feet of properties for sale, with an estimated market value of $279,875,900.

Prices for stores in Florence, SC start at $50,000, averaging $689,349, and reaching up to $13,230,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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