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    South Carolina Office Units for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    Showing 24 of 1,028 listings
    Prime Showroom/Office/Automotive Space Available
    $8,700,000 SF/Yr
    24,000 SF
    Prime Showroom/Office/Automotive Space Available

    Rare opportunity on US Hwy 17 corridor in West Ashley.

    2137 Savannah Highway, Charleston, SC 29414

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    Highway 170 Retail/Office/Medical Space
    $36 SF/Yr
    3,970 SF
    Highway 170 Retail/Office/Medical Space

    Retail, office, or medical space for sale on Highway 170.

    Bluffton, SC 29909

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    Class A Mixed-Use Redevelopment
    $28 SF/Yr
    3,190 SF
    Class A Mixed-Use Redevelopment

    Located in Greenville’s Historic Westend, easily accessible to major routes.

    400 Augusta Street, Greenville, SC 29601

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    Daniel Island Office Space Available
    $32 SF/Yr
    3,975 SF
    Daniel Island Office Space Available

    Second-floor office suite in Daniel Island's Town Center.

    115 Riverlanding Dr, Charleston, SC

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    Flex Space Near Interstate I-26
    $15 SF/Yr
    2,520 SF
    Flex Space Near Interstate I-26

    Professional flex and light manufacturing space with easy interstate access.

    104 Corporate Boulevard, West Columbia, SC 29169

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    Flex Space Near Interstate Access
    $15 SF/Yr
    1,575 SF
    Flex Space Near Interstate Access

    Professional flex and light manufacturing space with convenient interstate access.

    101 Corporate Boulevard, West Columbia, SC 29169

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    Rock Hill Office Suite Available
    $19 SF/Yr
    1,919 SF
    Rock Hill Office Suite Available

    Professional office suite with reception, offices, conference room, and breakroom.

    1674 Cranium Dr, Suite 102, Rock Hill, SC 29732

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    Functional Space in Sea Island
    $12 SF/Yr
    2,710 SF
    Functional Space in Sea Island

    2,710 SF warehouse and office space for lease.

    3609 River Road, Johns Island, SC 29455

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    Loft Retail and Office Space
    $20 SF/Yr
    20,000 SF
    Loft Retail and Office Space

    Retail and office spaces in historic Woodside Mill district.

    1 E Main Street, Greenville, SC 29611

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    Prime Office Space on Devine
    $23 SF/Yr
    12,200 SF
    Prime Office Space on Devine

    Office space for lease in the Devine Street District.

    2422 Devine Street, Columbia, SC 29205

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    Myrtle Beach Office Space
    $3,250/Mo
    2,400 SF
    Myrtle Beach Office Space

    Office space available for rent in Myrtle Beach, SC.

    1455 Commerce Pl., Myrtle Beach, SC 29577

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    Spartanburg Storefront Retail/Office Space
    $15 SF/Yr
    2,046 SF
    Spartanburg Storefront Retail/Office Space

    Renovated 2,046 SF retail/office space in downtown Spartanburg.

    512 E Main St, Spartanburg, SC 29302

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    Mount Pleasant Office Space Available
    $895/Mo
    Mount Pleasant Office Space Available

    Office space for rent with parking, Wi-Fi, and conference room.

    845 Lowcountry Blvd, Mount Pleasant, SC 29464

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    Class A Office Space Available
    $24 SF/Yr
    3,607 SF
    Class A Office Space Available

    Office space for lease in Myrtle Beach, available November 2025.

    2050 Corporate Center Dr., Myrtle Beach, SC 29577

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    Class A Office Suite
    $1,000/Mo
    Class A Office Suite

    Brand-new second-floor office suite with kitchenette access, common restrooms, dedicated fiber, and on-site parking.

    101 Lady'S Island Commons, Beaufort, SC 29907

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    Warehouse with Secured Yard
    $12 SF/Yr
    5,000 SF
    Warehouse with Secured Yard

    5,000 SF warehouse with office and secured yard.

    125 North Shorecrest Drive, Columbia, SC 29209

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    Flex Space Near I-26
    $10 SF/Yr
    3,000 SF
    Flex Space Near I-26

    3,000 SF flex space with office, warehouse, and laydown yard.

    7120 Broad River Road, Irmo, SC 29063

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    Class A Second-Floor Office Suite
    $800/Mo
    Class A Second-Floor Office Suite

    Brand-new Class A suite with shared kitchenette, common restrooms, fiber internet, and ample parking at Lady's Island Commons.

    101 Lady'S Island Commons, Beaufort, SC 29907

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    Office Space Near Government Buildings
    $2,000/Mo
    1,244 SF
    Office Space Near Government Buildings

    Office space with high visibility and convenient highway access.

    3844 Leeds Ave, North Charleston, SC 29405

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    Office Suite with Direct Elevator
    $42 SF/Yr
    2,625 SF
    Office Suite with Direct Elevator

    Third-floor office suite with open workspace and outdoor patio.

    121 Calhoun St, Charleston, SC 29401

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    Office Space with Open Floorplan
    $2,100/Mo
    1,150 SF
    Office Space with Open Floorplan

    Office unit featuring open floorplan and private offices for rent.

    A-8 Celadon Dr, Beaufort, SC 29907

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    First-Floor Office Suite
    $1,200/Mo
    First-Floor Office Suite

    New Class A office suite with kitchenette, ADA restroom access, and dedicated fiber internet in a parking-rich setting.

    101 Lady'S Island Commons, Beaufort, SC 29907

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    Flex Warehouse with Private Offices
    $1,995/Mo
    Flex Warehouse with Private Offices

    Lower-level flex space with a large open area, private offices, and rear truck-friendly access.

    65 Congress St N, York, SC 29745

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    Devine Street Office Space Available
    $18 SF/Yr
    10,500 SF
    Devine Street Office Space Available

    Office space for lease on highly trafficked Devine Street.

    2442 Devine St., Columbia, SC 29205

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