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    Florence, SC Office Properties & Spaces for Sale

    9 results
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    Versatile Commercial Property Near Downtown
    $550,000
    67,518 SF

    Versatile Commercial Property Near Downtown

    121 Lawson St, Florence, SC 29501

    Office, showroom, and warehouse space near downtown Florence, SC.

    • Versatile commercial space with office, showroom, and warehouse areas under one roof.
    • Located less than one mile from Downtown Florence, SC.
    • Approximately 7,500 sq ft of heated and cooled office and showroom space with 9 offices and 3 showroom suites.
    • Zoned Light Industrial, allowing a wide range of permitted uses.
    • Multiple loading docks, delivery doors, and drive‑in doors for warehouse accessibility.
    Updated: Feb 16
    View details
    Industrial Buildings with Power & Access
    $199,000
    40,000 SF

    Industrial Buildings with Power & Access

    120 N Guerry St, Florence, SC 29501

    Two industrial buildings ideal for fabrication, automotive, or storage.

    • Two standalone industrial buildings offer flexibility for various uses.
    • Light Industrial zoning supports a wide range of commercial and industrial operations.
    • Brick building features approximately 20‑foot ceilings, three‑phase power, and three roll‑up doors.
    • Concrete block building includes 5,000 SF of interior space plus 2,000 SF of covered area and interior office space.
    • Ideal for fabrication, automotive uses, contractor operations, or storage.
    Updated: Feb 28
    View details
    Florence Commercial Building on Evans
    $79,000
    1,200 SF

    Florence Commercial Building on Evans

    Standalone building on Evans Street with redevelopment potential.

    617 W Evans St, Florence, SC 29501
    View details
    Florence Office Building For Sale
    $1,500,000
    7,517 SF

    Florence Office Building For Sale

    Office building with 7,517 square feet of space in Florence.

    1706 2Nd Loop Rd, Florence, SC 29501
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    McLeod Physician Associates For Sale
    Contact for pricing
    2,666 SF

    McLeod Physician Associates For Sale

    2,666 SF medical office in Florence, SC for sale.

    1540 American Dr, Florence, SC 29505
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    Medical Office Building Near MUSC
    Contact for pricing
    7,950 SF

    Medical Office Building Near MUSC

    Medical office building near MUSC campus with ample parking.

    1929 Mountain Laurel Ct, Florence, SC 29505
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    Downtown Florence Business Technology Center
    Contact for pricing
    119,567 SF

    Downtown Florence Business Technology Center

    Office building in downtown Florence with investment and value-add potential.

    187 E Evans St, Florence, SC 29506
    View details
    Historic Downtown Florence Medical Office
    $1,350,000
    12,411 SF

    Historic Downtown Florence Medical Office

    12,411 SF Medical Office Building, $1.35M

    329 Irby St, Florence, SC 29501
    View details
    Florence Office Building - $285K
    $285,000
    1,829 SF

    Florence Office Building - $285K

    1,829 SF Office, High Traffic Area

    2400 2Nd Loop Rd, Florence, SC 29501
    View details
    Based on your search, we've compiled 463 Potential Opportunities for your consideration. Besides 9 Active listings in Florence, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 446 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Hartsville Commercial Property with Warehouse
    $480,000
    4,800 SF

    Hartsville Commercial Property with Warehouse

    Commercial property featuring office space and a warehouse in Hartsville.

    756 S 4Th St, Hartsville, SC 29550
    View details
    Hartsville Commercial Office For Sale
    $265,000
    3,258 SF

    Hartsville Commercial Office For Sale

    Commercial office space available for purchase in Hartsville, South Carolina.

    640 S 4Th St, Hartsville, SC 29550
    View details
    Stand-Alone Office Building For Sale
    $250,000
    1,722 SF

    Stand-Alone Office Building For Sale

    Stand-alone office building with immediate occupancy in Lake City, SC.

    215 John St, Lake City, SC 29560
    View details
    Updated Commercial Building with Showroom
    $1,600,000

    Updated Commercial Building with Showroom

    Updated 15,600 SF commercial building with showroom and loading docks.

    209 N Church St, Lake City, SC 29560
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Florence Commercial Land For Sale
    $49,900
    0.17 Acres

    Florence Commercial Land For Sale

    B-6 zoned property with commercial and redevelopment options.

    720 S Barringer St, Florence, SC 29506
    View details
    Commercial Lot on Darlington Street
    $31,000
    0.19 Acres

    Commercial Lot on Darlington Street

    Commercial lot with frontage on East Darlington Street, Florence, SC.

    East Darlington St, Florence, SC 29506
    View details
    Florence Commercial Lot For Sale
    $1,500,000
    4.02 Acres

    Florence Commercial Lot For Sale

    4.02 acre mixed-use lot with high visibility in Florence, SC.

    1714 2Nd Loop Rd, Florence, SC 29501
    View details
    Prime Commercial Development Site
    $980,000
    4.76 Acres

    Prime Commercial Development Site

    4.76-acre commercial land with high traffic exposure in Florence, SC.

    917 S Cashua Dr, Florence, SC 29501
    View details

    Explore Off-Market Properties in Florence, SC

    Consider similar Off-Market properties in Florence, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2601 Tv Rd

    2601 Tv Rd

    OFFICE BUILDING • 2,800 SF
    Value Estimation by Request
    2601 Tv Rd, Florence, SC 29501-0703
    View details
    255 Warley St

    255 Warley St

    OFFICE BUILDING • 3,590 SF
    Value Estimation by Request
    255 Warley St, Florence, SC 29501-4444
    View details
    531 Evans St

    531 Evans St

    OFFICE BUILDING • 1,948 SF
    Value Estimation by Request
    531 Evans St, Florence, SC 29501-3407
    View details
    Florence, SC 29505

    Florence, SC 29505

    OFFICE BUILDING • 1,130 SF
    Value Estimation by Request
    Florence, SC 29505
    View details
    Hwy 76th 301

    Hwy 76th 301

    OFFICE BUILDING • 2,128 SF
    Value Estimation by Request
    Hwy 76th 301, Florence, SC 29506
    View details
    Florence, SC 29501

    Florence, SC 29501

    OFFICE BUILDING • 22,400 SF
    Value Estimation
    $2,240,000
    Florence, SC 29501
    View details
    1825 Palmetto St

    1825 Palmetto St

    MEDICAL BUILDING • 11,322 SF
    Value Estimation by Request
    1825 Palmetto St, Florence, SC 29501-4137
    View details
    1250 Celebration Blvd

    1250 Celebration Blvd

    OFFICE BUILDING • 1,524 SF
    Value Estimation by Request
    1250 Celebration Blvd, Florence, SC 29501-5498
    View details
    204 Cheves St

    204 Cheves St

    MEDICAL BUILDING • 11,545 SF
    Value Estimation by Request
    204 Cheves St, Florence, SC 29506-2604
    View details
    187 Evans St

    187 Evans St

    OFFICE BUILDING • 64,416 SF
    Value Estimation
    $4,345,000
    187 Evans St, Florence, SC 29506-2511
    View details
    121 Cedar St

    121 Cedar St

    DENTAL BUILDING • 196,724 SF
    Value Estimation
    $1,890,000
    121 Cedar St, Florence, SC 29506-2576
    View details
    780 Woody Jones Blvd

    780 Woody Jones Blvd

    OFFICE BUILDING • 7,860 SF
    Value Estimation
    $1,020,000
    780 Woody Jones Blvd, Florence, SC 29501-7433
    View details
    1949 Darlington St

    1949 Darlington St

    Land • 2.63 Acres
    Value Estimation by Request
    1949 Darlington St, Florence, SC 29501
    View details
    1835 Fairfield Cir

    1835 Fairfield Cir

    OFFICE BUILDING • 624 SF
    Value Estimation by Request
    1835 Fairfield Cir, Florence, SC 29501-6943
    View details
    2325 Irby St

    2325 Irby St

    OFFICE BUILDING • 2,442 SF
    Value Estimation by Request
    2325 Irby St, Florence, SC 29505-3426
    View details

    Florence, SC Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 455 office properties & spaces for sale in Florence, SC, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 14,552,564 square feet of properties for sale, with an estimated market value of $127,808,000.

    Sale prices for office spaces in Florence, SC start at $50,000, averaging $652,081, and reaching up to $15,640,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Most Searched ZIP Codes in Florence, SC

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