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    Florence, SC Office Properties & Spaces for Sale

    8 results
    Notify Me
    Florence Office Building For Sale
    $1,500,000
    7,517 SF

    Florence Office Building For Sale

    1706 2Nd Loop Rd, Florence, SC 29501

    Office building with 7,517 square feet of space in Florence.

    • Handicap access: accessible approach with ramp.
    • Features office(s) and reception area.
    • Kitchen facility available.
    • Private restrooms.
    • Central heating and central air.
    Last Update: Oct 24
    View details
    Pamplico Highway Commercial Opportunity
    $229,900
    0.80 Acres

    Pamplico Highway Commercial Opportunity

    1424 Pamplico Hwy, Florence, SC 29505

    Commercial lot on heavily traveled Pamplico Highway with multiple driveways.

    • High‑traffic location on Pamplico Highway
    • Four driveways providing easy access
    • Suitable for retail or commercial development
    • Existing house usable as an office
    • Road frontage
    Last Update: Aug 14
    View details
    Historic Downtown Florence Medical Office
    $1,350,000
    12,411 SF

    Historic Downtown Florence Medical Office

    12,411 SF Medical Office Building, $1.35M
    329 Irby St, Florence, SC 29501
    View details
    Florence Office Building - $285K
    $285,000
    1,829 SF

    Florence Office Building - $285K

    1,829 SF Office, High Traffic Area
    2400 2Nd Loop Rd, Florence, SC 29501
    View details
    Medical Office Building Near MUSC
    $2,200,000
    7,950 SF

    Medical Office Building Near MUSC

    Medical office building near MUSC campus with ample parking.
    1929 Mountain Laurel Ct, Florence, SC 29505
    View details
    Historic Mixed-Use Building in Florence
    $3,000,000
    13 SF

    Historic Mixed-Use Building in Florence

    16,000 sq ft historic building in Downtown Florence for sale.
    248 W Evans St Florence, Florence, SC 29501
    View details
    Downtown Florence Business Technology Center
    $12,000,000
    119,567 SF

    Downtown Florence Business Technology Center

    Office building in downtown Florence with investment and value-add potential.
    187 E Evans St, Florence, SC 29506
    View details
    McLeod Physician Associates For Sale
    $1,384,320
    2,666 SF

    McLeod Physician Associates For Sale

    2,666 SF medical office in Florence, SC for sale.
    1540 American Dr, Florence, SC 29505
    View details
    Based on your search, we've compiled 461 Potential Opportunities for your consideration. Besides 8 Active listings in Florence, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 446 Off-Market properties to explore as potential leads, plus 3 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Veterinary Facility on Highway 76
    $440,000
    13,000 SF

    Veterinary Facility on Highway 76

    Spacious veterinary facility with medical office and boarding kennel.
    2608 Highway 76 E, Marion, SC 29571
    View details
    Marion Commercial Property with Garages
    $449,000
    Pending

    Marion Commercial Property with Garages

    Versatile commercial property with office, garages, and fenced yard.
    2152 Senator Gasque Hwy, Marion, SC 29571
    View details
    Hartsville Commercial Office For Sale
    $265,000
    3,258 SF

    Hartsville Commercial Office For Sale

    Commercial office space available in Hartsville, South Carolina.
    640 S 4Th St, Hartsville, SC 29550
    View details
    Hartsville Office Building For Sale
    $1,200,000
    5,000 SF

    Hartsville Office Building For Sale

    Prime Hartsville location, 5,000 sq ft office.
    146 Cargill Way, Hartsville, SC 29550
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Florence Commercial Land For Sale
    $49,900
    0.17 Acres

    Florence Commercial Land For Sale

    Versatile B-6 zoned property with commercial and redevelopment potential.
    720 S Barringer St, Florence, SC 29506
    View details
    Florence Commercial Lot For Sale
    $1,500,000
    4.02 Acres

    Florence Commercial Lot For Sale

    4.02 acre mixed-use lot with high visibility in Florence, SC.
    1714 2Nd Loop Rd, Florence, SC 29501
    View details
    Commercial Lot on Darlington Street
    $31,000
    0.19 Acres

    Commercial Lot on Darlington Street

    Commercial lot with frontage on East Darlington Street, Florence, SC.
    East Darlington St, Florence, SC 29506
    View details

    Explore Off-Market Properties in Florence, SC

    Consider similar Off-Market properties in Florence, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1092 Church St

    1092 Church St

    Flex space
    Value Estimation by Request
    1092 Church St, Florence, SC 29506
    View details
    650 Pamplico Hwy

    650 Pamplico Hwy

    Medical offices • 2,500 SF
    Value Estimation by Request
    650 Pamplico Hwy, Florence, SC 29505
    View details
    211 Pamplico Hwy

    211 Pamplico Hwy

    Office Properties & Spaces • 9,600 SF
    Value Estimation by Request
    211 Pamplico Hwy, Florence, SC 29505
    View details
    102 Sebrell St

    102 Sebrell St

    Office Properties & Spaces • 1,000 SF
    Value Estimation by Request
    102 Sebrell St, Florence, SC 29505
    View details
    1947 Hoffmeyer Rd

    1947 Hoffmeyer Rd

    Medical offices
    Value Estimation by Request
    1947 Hoffmeyer Rd, Florence, SC 29501
    View details
    400 Evans St

    400 Evans St

    Office Properties & Spaces • 2,400 SF
    Value Estimation by Request
    400 Evans St, Florence, SC 29501
    View details
    1800 2Nd Loop Rd

    1800 2Nd Loop Rd

    Office Properties & Spaces • 7,900 SF
    Value Estimation by Request
    1800 2Nd Loop Rd, Florence, SC 29501
    View details
    609 2Nd Loop Rd

    609 2Nd Loop Rd

    Medical offices • 3,600 SF
    Value Estimation by Request
    609 2Nd Loop Rd, Florence, SC 29505
    View details
    1224 Broughton Blvd

    1224 Broughton Blvd

    Flex space • 1,250 SF
    Value Estimation by Request
    1224 Broughton Blvd, Florence, SC 29501
    View details
    215 3rd Loop Rd

    215 3rd Loop Rd

    OFFICE BUILDING • 10,709 SF
    Value Estimation by Request
    215 3rd Loop Rd, Florence, SC 29505-4717
    View details
    151 Evans St

    151 Evans St

    OFFICE BUILDING • 14,829 SF
    Value Estimation by Request
    151 Evans St, Florence, SC 29501-3425
    View details
    1714 Gregg Ave

    1714 Gregg Ave

    MEDICAL BUILDING • 4,969 SF
    Value Estimation by Request
    1714 Gregg Ave, Florence, SC 29501-4120
    View details
    2200 Irby St

    2200 Irby St

    MEDICAL BUILDING • 5,996 SF
    Value Estimation
    $3,130,000
    2200 Irby St, Florence, SC 29505-3423
    View details
    142 Dargan St

    142 Dargan St

    OFFICE BUILDING • 6,255 SF
    Value Estimation by Request
    142 Dargan St, Florence, SC 29506-2500
    View details
    255 Warley St

    255 Warley St

    OFFICE BUILDING • 3,590 SF
    Value Estimation by Request
    255 Warley St, Florence, SC 29501-4444
    View details
    520 Palmetto St

    520 Palmetto St

    OFFICE BUILDING • 1,897 SF
    Value Estimation
    $275,000
    520 Palmetto St, Florence, SC 29501-4428
    View details

    Florence, SC Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 453 office properties & spaces for sale in Florence, SC, showcased through 8 active listings on our real estate platform. These investment opportunities span a total of 14,475,028 square feet of properties for sale, with an estimated market value of $127,209,900.

    Prices for office spaces in Florence, SC start at $50,000, averaging $655,721, and reaching up to $15,640,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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    Browse Office Properties & Spaces for Sale Near Florence, SC

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    Most Searched ZIP Codes in Florence, SC

    • 29501
    • 29505
    • 29506

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