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San Diego County, CA Office Spaces for Sale

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Freestanding Office Building
Updated: Jun 25
Freestanding Office Building

5050 Federal Boulevard, San Diego, CA 92102

$3,300,000
9,930 sqft 0.58 AC lot
±9,930 SF freestanding building on a ±0.58 AC lot
Renovated in 2019 with reception area, ±12 rooms, storage closets, and multiple restrooms
CC‑2‑3 zoning and Opportunity Zone designation
Six‑car garage plus rear gated parking and front/rear ingress and egress
Adjoined one‑bedroom apartment with kitchenette and central AC/heat
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5050 Federal Boulevard, San Diego, CA 92102

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Two-Unit Office Building
Updated: Aug 25
Two-Unit Office Building

651-53 E. Valley Packway, Escondido, CA 92025

$725,000
0.07 AC lot
Two office units within one commercial building
0.0671‑acre parcel at 651‑53 E. Valley Packway
Parking located behind the building
Near new condominiums, retail shops, and restaurants
Slab flooring with forced‑air, natural‑gas, and central heating
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Corner-Lot Mixed-Use Property
Corner-Lot Mixed-Use Property

3275 Euclid, San Diego, CA 92105

$900,000
0.11 AC lot

Versatile storefront property with separate business and private-access entrances in a transit-oriented commercial setting.

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Five-Suite Mixed-Use Property
Five-Suite Mixed-Use Property

2344 Highway 67, Ramona, CA 92065

$1,295,000
0.70 AC lot

The property has commercial zoning, on-site parking, and five suites.

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Fenced-Yard Flex Space
Fenced-Yard Flex Space

9220 Jamacha Road, Spring Valley, CA 91977

$2,200,000
3,600 sqft 0.30 AC lot

M54 zoning supports industrial use, with office and warehouse areas plus utility connections already in place.

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Live-Work Office Flex Space
Live-Work Office Flex Space

2487 Kettner Blvd, San Diego, CA 92101

$1,149,000
1,610 sqft 0.02 AC lot

Two office suites plus a flex garage space, upgraded full bath and two kitchens; no HOA.

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Mixed-Use Office and Retail Units
Mixed-Use Office and Retail Units

825-829 Washington St., San Diego, CA 92103

$1,189,000
1,778 sqft 0.03 AC lot

Three remodeled office and retail units at 825-829 Washington St. offer extensive exterior and systems upgrades.

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Mixed-Use Property with Courtyard
Mixed-Use Property with Courtyard

110 Maple St, San Diego, CA 92103

$4,890,000
0.13 AC lot

A corner commercial asset combines a leased office component with remodeled residences and a landscaped shared outdoor area.

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Two-Structure Flex Property
Two-Structure Flex Property

3946 La Salle St, San Diego, CA 92110

$1,650,000

Street-facing retail or office space is paired with an open shop area for flexible commercial use.

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Freestanding Office Building with Parking
Freestanding Office Building with Parking

6334 University Avenue, San Diego, CA 92115

$950,000

Freestanding office building operating as a mortuary, with chapel/viewing space and rear access plus on-site parking.

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Freestanding Office Building
Freestanding Office Building

6334 University Ave, San Diego, CA 92115

$950,000
2,273 sqft

Functional office configuration with reception areas, private rooms, monument signage, rear access, and on-site parking.

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Operational Office Unit with Security Business
Operational Office Unit with Security Business

911 S Andreasen, Escondido, CA 92029

$799,999

Leased office space supports an established security and patrol operation serving residential and commercial accounts.

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Flex Space with Loading Dock
Flex Space with Loading Dock

3065 Beyer Boulevard, San Diego, CA 92154

$1,990,000

Flexible industrial space includes office reception, central air, and rear loading access.

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Flex Property with Secured Yard
Flex Property with Secured Yard

1338 D St., Ramona, CA 92065

$1,150,000
2,968 sqft

Two-level layout combines professional offices, an automotive shop, and secured outdoor yard space.

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Renovated Coworking Space
Renovated Coworking Space

4526-38 CASS STREET, San Diego, CA 92109

Contact for pricing
0.17 AC lot

Flexible private and semi-private offices include shared business amenities with month-to-month availability.

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Commercial Mixed-Use Property
Commercial Mixed-Use Property

2617 C St, Julian, CA 92036

$725,000
0.23 AC lot

A granted commercial variance covers office, retail, and industrial uses.

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Ground-Floor Office Condo Suite
Ground-Floor Office Condo Suite

3740 Park Boulevard Cu1, San Diego, CA 92103

$2,100,000
2,360 sqft

Modern ground-floor office condo built in 2007 with private offices, reception, open work areas, and multiple entrances.

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Remodeled Corner Office Unit
Remodeled Corner Office Unit

3400 Piazza de Oro Suite 160, Oceanside, CA 92056

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Open-plan workspace with a private office, kitchen, reserved parking, and access to shared community amenities.

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Single-Tenant Office Building with Billboard
Single-Tenant Office Building with Billboard

8167-69 Center Street, La Mesa, CA 91942

$1,700,000
5,236 sqft

The property combines full occupancy with rooftop billboard space and M Zone industrial zoning near the (8) Freeway.

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Retail Space in Old Barn Building
Retail Space in Old Barn Building

780 Main Street Ste B, Ramona, CA 92065

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Suite B includes heat-pump climate control and access to a private, illuminated parking area behind the building.

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Three-Story Mixed-Use Building
Three-Story Mixed-Use Building

2368 2nd Ave, San Diego, CA 92101

$2,669,000
3,800 sqft

Three-story mixed-use building features independently accessible floors with private in- and egress and onsite parking.

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Updated Office Suite
Updated Office Suite

301 Enterprise St, Suite 3, Escondido, CA 92029

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Flexible workspace with multiple private offices, a client reception area, natural light, and an in-suite restroom.

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Freestanding Office Building
Freestanding Office Building

845 Otay Lakes Road, Chula Vista, CA 91913

$1,600,000
3,200 sqft

Eastern Chula Vista property across from Southwestern College with on-site parking and R-1 zoning.

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Renovated Office Units
Renovated Office Units

9633 Grossmont Summit Dr., La Mesa, CA 91941

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Updated second-level office space with flexible configuration, air conditioning, private bathroom, and included parking.

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San Diego County, CA Office Spaces Market Trends and Statistics

Explore 466 office spaces for sale in San Diego County, CA, showcased through 466 active listings on our real estate platform. These investment opportunities span a total of 4,090,306 square feet of properties for sale, with an estimated market value of $148,646,662.

Sale prices for office spaces in San Diego County, CA start at $328,000, averaging $2,093,614, and reaching up to $31,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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