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    Charleston County, SC Office Properties & Spaces for Lease

    89 results
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    Showroom and Office Space
    $30 SF/Yr
    1,000 SF

    Showroom and Office Space

    3436 Maybank Hwy, Johns Island, SC 29455

    1,000 SF showroom/office space on Maybank Highway for rent.

    • High visibility location on Maybank Highway
    • 1,000 SF showroom and office space
    • Updated and bright in‑line space
    • Prominent exterior monument signage
    • Ample on‑site parking
    View details
    Turn Key Medical Office Space
    $29 SF/Yr
    2,587 SF

    Turn Key Medical Office Space

    897 Von Kolnitz Rd, Mount Pleasant, SC 29464

    Move-in ready medical office space near East Cooper Hospital.

    • Turn‑key medical office space ready for immediate move‑in.
    • Prime location directly across from East Cooper Hospital.
    • Centrally located in Mount Pleasant, SC, with easy access to I‑526 and downtown Charleston.
    • Ideal for medical businesses due to proximity to other healthcare providers and potential referral opportunities.
    • Well‑designed layout including a private waiting room, reception area, exam rooms, offices, nurse station with kitchenette, and storage.
    View details
    Class A Medical Office Building
    $28 SF/Yr
    14,084 SF

    Class A Medical Office Building

    Renovated medical/office building in Mt. Pleasant, ample parking.

    1200 Innovation Way, Mount Pleasant, SC 29466
    View details
    Johns Island Office Suite
    $30 SF/Yr
    550 SF

    Johns Island Office Suite

    550 SF office suite in the heart of Johns Island.

    3546 Maybank Hwy, Johns Island, SC 29455
    View details
    Move-in Ready Office Space
    $25 SF/Yr
    1,885 SF

    Move-in Ready Office Space

    Move-in ready office space in Live Oak Square.

    1814 Crowne Cmns Way, Johns Island, SC
    View details
    Mt. Pleasant Office/Medical Space
    $12 SF/Yr
    6,185 SF

    Mt. Pleasant Office/Medical Space

    Office and medical suites available in Mt. Pleasant location.

    900 Bowman Rd, Mt Pleasant, SC 29464
    View details
    Functional Office Suite For Rent
    $700 / Mo
    178 SF

    Functional Office Suite For Rent

    Office suite with functional layout in desirable location.

    1233 Ben Sawyer Blvd, Mount Pleasant, SC 29464
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    Mount Pleasant Office Space Available
    $28 SF/Yr
    352 SF

    Mount Pleasant Office Space Available

    Office space in a well-maintained park with included utilities.

    503 Wando Park Blvd, Mount Pleasant, SC 29464
    View details
    New Office Building in Mount Pleasant
    $37 SF/Yr
    9,849 SF

    New Office Building in Mount Pleasant

    Newly constructed office building in desirable Mount Pleasant location.

    1681 Belle Isle Ave, Mount Pleasant, SC 29464
    View details
    Mount Pleasant Office Space Available
    $1,065,000
    3,762 SF

    Mount Pleasant Office Space Available

    Professional office suites available in Mount Pleasant sub-market of Charleston.

    421 Wando Park Blvd, Mount Pleasant, SC 29464
    View details
    Mount Pleasant Office Condo For Lease
    Contact for pricing
    2,880 SF

    Mount Pleasant Office Condo For Lease

    Well-appointed office condo with efficient layout and ample parking.

    852-856 Lowcountry Blvd, Mt Pleasant, SC 29464
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    Mixed-Use Development on Highway 41
    $28 SF/Yr
    16,000 SF

    Mixed-Use Development on Highway 41

    Multi-building development ideal for retail and office space.

    1031 Highway 41, Mount Pleasant, SC 29466
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    Mount Pleasant Office Condo For Lease
    Contact for pricing
    2,880 SF

    Mount Pleasant Office Condo For Lease

    Well-appointed office condo in central Mount Pleasant location.

    856 Lowcountry Blvd, Mount Pleasant, SC 29464
    View details
    Versatile Flex Space in Hollywood
    Contact for pricing
    2,000 SF

    Versatile Flex Space in Hollywood

    2000 SF flex space available for rent in Hollywood, SC.

    Highway 165, Hollywood, SC 29449
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    Mount Pleasant Office Space Available
    Contact for pricing
    1,600 SF

    Mount Pleasant Office Space Available

    Office space featuring private offices, conference area, and kitchen.

    1041 Johnnie Dodds Blvd, Mount Pleasant, SC 29464
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    Mount Pleasant Office Space Available
    Contact for pricing
    3,400 SF

    Mount Pleasant Office Space Available

    3,400 SF office space with ample parking and signage.

    790 Johnnie Dodds Blvd, Mount Pleasant, SC 29464
    View details
    Class A Office Space Available
    Contact for pricing
    3,700 SF

    Class A Office Space Available

    Class A office space for rent in Mount Pleasant.

    Bridgeside Blvd, Mount Pleasant, SC 29464
    View details
    Move-in Ready Office Space
    Contact for pricing
    2,494 SF

    Move-in Ready Office Space

    Office space in a desirable location near shopping and dining.

    496 Bramson Ct, Mount Pleasant, SC 29464
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    Mount Pleasant Office Space Available
    Contact for pricing
    4,564 SF

    Mount Pleasant Office Space Available

    Office space featuring private offices, break rooms, and conference room.

    1156 Bowman Rd, Mount Pleasant, SC 29464
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    Medical/Professional Office Space Available
    Contact for pricing
    4,211 SF

    Medical/Professional Office Space Available

    Single-story office space ready for upfits near new developments.

    2947 Maybank Hwy, Johns Island, SC 29455
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    Renovated Office Space Available
    Contact for pricing
    960 SF

    Renovated Office Space Available

    960 SF office space with excellent visibility.

    900 Main Rd, Johns Island, SC 29455
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    Modern Office Space in Mount Pleasant
    Contact for pricing
    17,374 SF

    Modern Office Space in Mount Pleasant

    Plug-and-play workspace in a prime Mount Pleasant location.

    11 Ewall St, Mount Pleasant, SC 29464
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    Mount Pleasant Office Space Available
    Contact for pricing
    2,281 SF

    Mount Pleasant Office Space Available

    Office suite with deck space and creek views for rent.

    410 Mill St, Mount Pleasant, SC 29464
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    Single-Story Office in Wando Commons
    Contact for pricing
    2,263 SF

    Single-Story Office in Wando Commons

    Single-story office space with convenient access to major routes.

    498 Wando Park Blvd, Mount Pleasant, SC 29464
    View details

    Charleston County, SC Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in Charleston County, SC with 119 listings featured on our commercial real estate exchange. The current inventory includes 59,812,715,160 square feet of properties with an estimated lease value of $1,622 /Mo.

    Estimated lease rates for Office Properties & Spaces in Charleston County, SC begin at $1.64 SF/Yr, with an average of $27 SF/Yr and extend to $84 SF/Yr.
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    Office Properties & Spaces by market

    Browse Office Properties & Spaces for Lease Near Charleston, SC

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