Sign Up Successful!
You now have access to more from Realmo!
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Office
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search
    List
    Map

    Beaufort County, SC Office Properties & Spaces for Lease

    43 results
    Notify Me
    New
    Beaufort Flex Space For Rent
    $17 SF/Yr
    54,450 SF

    Beaufort Flex Space For Rent

    2712 Bull St,Unit C, Beaufort, SC 29902

    1,000 SF flex space near Downtown Beaufort.

    • Prime Location: Just off the Spanish Moss Trail and minutes from Downtown Beaufort.
    • Versatile Space: Wide open layout suitable for offices, fitness centers, studios, and other creative uses.
    • Flexible Zoning: Zoned T4‑NA, allowing for a variety of business types.
    • ADA Compliant: Includes one ADA compliant bathroom.
    • First Floor Unit: Convenient access on the first floor.
    Last Update: Dec 9
    View details
    New
    Port Royal Office Spaces Available
    $750 /Mo
    44,431 SF

    Port Royal Office Spaces Available

    1319 Ladys Island Dr,Unit 1-5, Port Royal, SC 29935

    New office building with individual offices for rent.

    • Centrally located in Port Royal, SC, offering convenient access.
    • Brand new office building with modern amenities.
    • Multiple office sizes available (85‑210 sq ft) to suit various needs.
    • Shared conference room for professional meetings.
    • Ample parking in a large parking lot.
    Last Update: Dec 9
    View details
    New
    Versatile Commercial Space in Beaufort
    $4,500 /Mo
    1,307 SF

    Versatile Commercial Space in Beaufort

    Two-level commercial building suitable for various business types.
    8 Celadon Dr, Beaufort, SC 29907
    View details
    Downtown Beaufort Office Suite
    $525 /Mo

    Downtown Beaufort Office Suite

    Professional office suite in historic downtown Beaufort, South Carolina.
    711 Bladen Street Ln, Beaufort, SC 29902
    View details
    Port Royal Office/Creative Space
    $1,250 /Mo
    871 SF

    Port Royal Office/Creative Space

    Renovated 750 SF office/creative space in iconic Arts Building.
    1404 Paris Ave, Port Royal, SC 29935
    View details
    Office Suite in Beaufort, SC
    $600 /Mo

    Office Suite in Beaufort, SC

    Conveniently located office suite near downtown Beaufort.
    2201 Boundary St, Beaufort, SC 29902
    View details
    Commercial Space on Lady's Island
    $575 /Mo

    Commercial Space on Lady's Island

    Multi-tenant commercial building near downtown Beaufort and Beaufort High School.
    9a Rue Du Bois, Ladys Island, SC 29907
    View details
    Downtown Beaufort Office Space
    $1,100 /Mo
    436 SF

    Downtown Beaufort Office Space

    Charming office space in downtown Beaufort with waterfront views.
    1011 Bay St, Beaufort, SC 29902
    View details
    Lady's Island Multi-Use Space
    $750 /Mo

    Lady's Island Multi-Use Space

    Multi-use commercial space available on Lady's Island, SC.
    9 Rue Du Bois, Ladys Island, SC 29907
    View details
    Prime Beaufort Office Space Available
    $800 /Mo
    6,970 SF

    Prime Beaufort Office Space Available

    100 SF office space in a prime, central Beaufort location.
    205 Ribaut Rd, Beaufort, SC 29902
    View details
    Beaufort Office Space For Rent
    $800 /Mo
    6,970 SF

    Beaufort Office Space For Rent

    Office space in a prime, central Beaufort location.
    205 Ribaut Rd, Beaufort, SC 29902
    View details
    Beaufort Office Space For Rent
    $1,300 /Mo
    6,970 SF

    Beaufort Office Space For Rent

    240 SF office space in a prime, central Beaufort location.
    205 Ribaut Rd, Beaufort, SC 29902
    View details
    Renovated Retail/Office Space in Beaufort
    $1,833 /Mo
    3,485 SF

    Renovated Retail/Office Space in Beaufort

    Historic Beaufort location ideal for retail, office, or service businesses.
    609 Carteret St, Beaufort, SC 29902
    View details
    Commercial Space in Beaufort, SC
    $30 SF/Yr

    Commercial Space in Beaufort, SC

    New construction commercial space available for rent in Beaufort.
    960 Ribaut Rd, Beaufort, SC 29902
    View details
    Salon Suite in Port Royal
    $625 /Mo

    Salon Suite in Port Royal

    80 sq ft salon suite available for rent.
    2206 Mossy Oaks Rd, Port Royal, SC 29935
    View details
    New Custom-Built Office Suites
    $1,500 /Mo
    3,049 SF

    New Custom-Built Office Suites

    Pre-leasing custom office suites with private entrances, available Q2 2026.
    101 Ladys Is Cmns, Ladys Island, SC 29907
    View details
    Renovated Office Space Available
    $1,900 /Mo
    436 SF

    Renovated Office Space Available

    Newly renovated 650 SF office space in Lady's Island.
    1 Merchants Ln, Ladys Island, SC 29907
    View details
    Office/Storage Space with Land
    $1,000 /Mo
    1,307 SF

    Office/Storage Space with Land

    Commercial office/storage space with ample land in Beaufort, SC.
    40 Shanklin Rd, Beaufort, SC 29906
    View details
    Renovated Retail/Office Space in Beaufort
    $2,736 /Mo

    Renovated Retail/Office Space in Beaufort

    Historic Beaufort location, renovated space, ideal for retail or office.
    609 Carteret St, Beaufort, SC 29902
    View details
    Hilton Head Medical Office Suites
    $22 SF/Yr
    4,299 SF

    Hilton Head Medical Office Suites

    Prime Medical Space, North End Lease
    100 Exchange St, Hilton Head Island, SC 29926
    View details
    Hilton Head Island Office Space
    $17 SF/Yr
    1,546 SF

    Hilton Head Island Office Space

    1,546 sq ft, Prime Location, Water Views
    23B Shelter Cove Ln, Hilton Head Island, SC 29928
    View details
    Bluffton Office Space for Lease
    $27 SF/Yr
    2,378 SF

    Bluffton Office Space for Lease

    Class A Office, 2378 sq ft, Bluffton SC
    12 Arley Way, Bluffton, SC 29910
    View details
    Bluffton Medical Office Space for Lease
    $43 SF/Yr
    13,200 SF

    Bluffton Medical Office Space for Lease

    Modern Health & Wellness Center Suites Available
    Wy New Riverside Village Way, Bluffton, SC 29910
    View details
    Prime Boundary Street Office Space
    $19 SF/Yr
    5,000 SF

    Prime Boundary Street Office Space

    Versatile Office Suites, High Visibility
    1810 Boundary St, Beaufort, SC 29902
    View details

    Beaufort County, SC Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in Beaufort County, SC with 92 listings featured on our commercial real estate exchange. The current inventory includes 9,276,616,026 square feet of properties with an estimated lease value of $9,785 /Mo.

    Estimated lease rates for Office Properties & Spaces in Beaufort County, SC begin at $8 SF/Yr, with an average of $296 SF/Yr and extend to $1,900 /Mo.
    List
    Map

    Office Properties & Spaces by market

    Browse Office Properties & Spaces for Lease Near Beaufort, SC

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Create New Password
    • At least 8 characters
    • Contains both letters and numbers
    • Contains uppercase and lowercase letters
    • At most 32 characters
    • Password required
    • Password reset link has expired. Please request a new one.