Edwardsville, IL Office Properties & Spaces for Rent & Lease

$6,580 / Mo

3,290 SF

Edwardsville Office Building For Lease

4 Sunset Hills Professional Ctr, Edwardsville, IL 62025

3,290 SF office building in Sunset Hills Professional Centre.

3,290 SF standalone office building
Located in the well‑established Sunset Hills Professional Centre
Prime location off IL‑157 in Edwardsville’s office/medical corridor
Main level features 7 private offices, conference room, and open bullpen
Finished break room and two restrooms in the lower level

Updated: Oct 16, 2025

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$500 / Mo

Office Suite in Edwardsville, IL

340 S Fillmore St, Edwardsville, IL 62025

Single office suite for lease with utilities included.

All utilities included in $500/month rent.
Located near downtown Edwardsville.
Access to MCT Bike Trail.
Ample parking available.
Shared conference room, kitchen, and bath.

Updated: Nov 26, 2025

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$2,300 / Mo

Class A Office Space

Prime office space in Edwardsville, IL for lease.

3 Club Centre Ct, Edwardsville, IL 62025

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Edwardsville Mixed-Use Retail/Office Space

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1,932 SF

Edwardsville Mixed-Use Retail/Office Space

New construction mixed-use building with retail, office, and restaurant spaces.

400 N Main St, Edwardsville, IL 62025

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7,266 SF

Edwardsville Office Suites for Lease

Office suites available in campus-like Mark Twain Plaza.

103 W Vandalia St, Edwardsville, IL 62025

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$24 SF/Yr

43,531 SF

Edwardsville Executive Office Suites

Prestigious Class A office space, IL.

101 Vandalia St, Edwardsville, IL 62025

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$12 SF/Yr

11,800 SF

Edwardsville Office Space Available

Prime Edwardsville Office Suites, 1,650-5,650 SF

1 Sunset Hills Professional Ctr, Edwardsville, IL 62025

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$24 SF/Yr

45,587 SF

Mark Twain Plaza II Office Space

Edwardsville, IL: Modern Office Suites Available

103 Vandalia St, Edwardsville, IL 62025

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$24 SF/Yr

38,574 SF

Mark Twain Plaza III Office Suites

Class A Executive Office Space Available

105 Vandalia St, Edwardsville, IL 62025

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$25 SF/Yr

12,104 SF

Edwardsville Office/Retail Space

Prime Downtown Edwardsville location, 2,520 SF available.

228 Main St, Edwardsville, IL 62025

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$24 SF/Yr

7,611 SF

Edwardsville Executive Office Suite

Downtown Edwardsville, 1207 SF Available

120 Main St, Edwardsville, IL 62025

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$9 SF/Yr

6,249 SF

Edwardsville Office Space Available

Flexible Offices, Coworking & More

101 Vandalia St, Edwardsville, IL 62025

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$20 SF/Yr

24,576 SF

Edwardsville Executive Office Space

Prime Office Suites, 455-6,329 SF Available

1012 Plummer Dr, Edwardsville, IL 62025

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$25 SF/Yr

15,030 SF

Edwardsville Office Space For Lease

Prime Downtown Location, 1,000 SF Available

100 Main St, Edwardsville, IL 62025

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$20 SF/Yr

2,166 SF

Edwardsville Executive Office Space

Newly renovated, 2166 sq ft office.

60 Edwardsville Professional Park, Edwardsville, IL 62025

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$30 SF/Yr

78,079 SF

Edwardsville Office Space - Downtown

Modern Executive Suites, Retail & More

400 Main St, Edwardsville, IL 62025

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$18 SF/Yr

12,137 SF

Edwardsville Executive Office Suites

Prime Edwardsville Office Space Available

201 Hillsboro Ave, Edwardsville, IL 62025

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$24 SF/Yr

78,720 SF

University Pointe Office Space

Edwardsville, IL Office Suites Available

1041 Century Dr, Edwardsville, IL 62025

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$12 SF/Yr

3,300 SF

Edwardsville Office Building For Lease

Historic Downtown Edwardsville Office Space

1310 Main St, Edwardsville, IL 62025

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Downtown Edwardsville Office/Retail Space

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1,000 SF

Downtown Edwardsville Office/Retail Space

Premier office/retail space in downtown Edwardsville at lighted intersection.

100 N Main St, Edwardsville, IL 62025

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3,300 SF

Edwardsville Office Building For Lease

3,300 SF office building in downtown Edwardsville for lease.

1310 N Main St, Edwardsville, IL 62025

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2,520 SF

Downtown Edwardsville Office Space

2,520 SF office space for lease in downtown Edwardsville.

228 N Main St, Edwardsville, IL 62025

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8,000 SF

Historic Office Space in Edwardsville

Unique creative office space in historic downtown Edwardsville, Illinois.

201 Hillsboro Ave, Edwardsville, IL 62025

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4,000 SF

Edwardsville Office Space For Rent

Office suite available in Sunset Hills Professional Center.

1 Sunset Hills Professional Ctr, Edwardsville, IL 62025

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Edwardsville, IL Office Properties & Spaces Leasing Opportunities Market Analysis

Explore Office Properties & Spaces leasing options in Edwardsville, IL with 35 listings featured on our commercial real estate exchange. The current inventory includes 18,894,672,720 square feet of properties with an estimated lease value of $654 /Mo.

Estimated lease rates for Office Properties & Spaces in Edwardsville, IL begin at $9 SF/Yr, with an average of $21 SF/Yr and extend to $30 SF/Yr.

Edwardsville, IL Office Properties & Spaces for Lease

Edwardsville Office Building For Lease

3,290 SF office building in Sunset Hills Professional Centre.

Office Suite in Edwardsville, IL

Single office suite for lease with utilities included.

Class A Office Space

Edwardsville Mixed-Use Retail/Office Space

Edwardsville Office Suites for Lease

Edwardsville Executive Office Suites

Edwardsville Office Space Available

Mark Twain Plaza II Office Space

Mark Twain Plaza III Office Suites

Edwardsville Office/Retail Space

Edwardsville Executive Office Suite

Edwardsville Office Space Available

Edwardsville Executive Office Space

Edwardsville Office Space For Lease

Edwardsville Executive Office Space

Edwardsville Office Space - Downtown

Edwardsville Executive Office Suites

University Pointe Office Space

Edwardsville Office Building For Lease

Downtown Edwardsville Office/Retail Space

Edwardsville Office Building For Lease

Downtown Edwardsville Office Space

Historic Office Space in Edwardsville

Edwardsville Office Space For Rent

Edwardsville, IL Office Properties & Spaces Leasing Opportunities Market Analysis

Browse Office Properties & Spaces for Lease Near Edwardsville, IL

Popular Searches in Edwardsville, IL

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Edwardsville, IL Office Properties & Spaces for Lease

Edwardsville Office Building For Lease

3,290 SF office building in Sunset Hills Professional Centre.

Office Suite in Edwardsville, IL

Single office suite for lease with utilities included.

Class A Office Space

Edwardsville Mixed-Use Retail/Office Space

Edwardsville Office Suites for Lease

Edwardsville Executive Office Suites

Edwardsville Office Space Available

Mark Twain Plaza II Office Space

Mark Twain Plaza III Office Suites

Edwardsville Office/Retail Space

Edwardsville Executive Office Suite

Edwardsville Office Space Available

Edwardsville Executive Office Space

Edwardsville Office Space For Lease

Edwardsville Executive Office Space

Edwardsville Office Space - Downtown

Edwardsville Executive Office Suites

University Pointe Office Space

Edwardsville Office Building For Lease

Downtown Edwardsville Office/Retail Space

Edwardsville Office Building For Lease

Downtown Edwardsville Office Space

Historic Office Space in Edwardsville

Edwardsville Office Space For Rent

Edwardsville, IL Office Properties & Spaces Leasing Opportunities Market Analysis

Browse Office Properties & Spaces for Lease Near Edwardsville, IL

Popular Searches in Edwardsville, IL

Most Searched ZIP Codes in Edwardsville, IL

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