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San Diego, CA Office Spaces for Lease

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Found 558 office space listings for lease in San Diego, CA, averaging $21/SF/YR. Use lease type data to compare options faster.
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San Diego Office Campus
San Diego Office Campus

3530, 3550, & 3570 Camino del Rio N, San Diego, CA 92108

Qualcomm
Contact for pricing
Built 1981  4.2 acres

Three-building office campus in central San Diego with modern renovations.

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Office Space Available For Lease
Office Space Available For Lease

1094 Cudahy Place, San Diego, CA 92110

Morena
Contact for pricing
Built 1972

Office space for lease at 1094 Cudahy Place, San Diego.

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Office Space For Rent
Office Space For Rent

3211 Holiday Ct, San Diego, CA

Little Italy
Contact for pricing
1 person  200 sqft  1.51 acres

Second floor office space available for rent.

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Leased Office Building
Leased Office Building

12220 El Camino Real, San Diego, CA 92130

Torrey Preserve
Contact for pricing
100%

Office building is currently 100% leased with no space available at this time.

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558 active listings match your search: Office for lease in San Diego, CA. Based on your search, we've also compiled 107 Potential Opportunities for your consideration: 4 spaces in nearby cities and 103 properties for sale.

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Space Near Hospital
Medical Office Space Near Hospital

230 Prospect Pl, Coronado, CA 92118

Contact for pricing
1,115 sqft

Available for lease beside Sharp Coronado Hospital, this space is suited to a medical-office use.

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Boutique Medical Office Space
Boutique Medical Office Space

5200 Lake Murray Blvd, La Mesa, CA

Contact for pricing
900 sqft  0.14 acres

Medical office space with pristine finishes and high-end aesthetics.

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Coronado Office Space Available
Coronado Office Space Available

1199 Orange Avenue, Coronado, CA 92118

Contact for pricing

Office space for rent at 1199 Orange Avenue, Coronado.

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Remodeled Second-Floor Office Suite
Remodeled Second-Floor Office Suite

7171 Alvarado Rd, La Mesa, CA 91942

Modified gross
Contact for pricing
3–5 people  3 spaces  800 sqft

Second-floor office suite with four offices, reception, and a waiting area, recently remodeled with fresh paint and new carpet.

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Similar Spaces for Sale in San Diego, CA

Consider Similar Space for Sale. We found 103 Spaces matching your search parameters.

Two-Story Medical Office Building
Two-Story Medical Office Building

4710 Ruffner St, San Diego, CA 92111

$3,250,000
10,000 sqft 0.35 AC lot

Four first-floor suites include two vacant spaces, with each unit separately metered.

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Medical Office Building with Historic Details
Medical Office Building with Historic Details

106 Thorn St, San Diego, CA 92103

$2,500,000
2,385 sqft 0.08 AC lot

The property is identified for office, retail, creative, live/work, multifamily, and single-family use paths.

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Penthouse Office Suite
Penthouse Office Suite

1350 Columbia St, San Diego, CA 92101

$3,875,000
6,678 sqft

The ninth-floor workspace includes collaborative seating, a glass-enclosed conference room, phone pods, and a hospitality bar.

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Freestanding Office Building
Freestanding Office Building

4394 30th, San Diego, CA 92104

$1,649,000
1,735 sqft 0.07 AC lot

Five private offices, a conference room, reception area, kitchen, and two restrooms support a functional workplace layout.

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Office Building with Kitchen
Office Building with Kitchen

3569 Fifth Avenue, San Diego, CA 92103

$5,550,000
10,870 sqft 0.11 AC lot

The property is expected to be vacant at delivery and contains five restrooms.

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Freestanding Office Building
Freestanding Office Building

5050 Federal Boulevard, San Diego, CA 92102

$3,300,000
9,930 sqft 0.58 AC lot

Renovated commercial office property with flexible rooms, accessible facilities, gated parking, and an adjoining apartment.

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Freestanding Office Building
Freestanding Office Building

6334 University Ave, San Diego, CA 92115

$950,000
2,273 sqft

Functional office configuration with reception areas, private rooms, monument signage, rear access, and on-site parking.

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Four-Story Mixed-Use Building
Four-Story Mixed-Use Building

920 Kline Street, La Jolla, CA 92037

$5,800,000
20,000 sqft 1.50 AC lot

Mixed retail and office occupancy is supported by an updated elevator and private baths in many suites.

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Freestanding Office Building
Freestanding Office Building

1501 5th Ave, San Diego, CA 92101

$8,500,000
43,670 sqft

Freestanding office asset offering immediate occupancy, customization flexibility, and access to downtown amenities and public transportation.

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Mixed-Use Building with Live-Work Layout
Mixed-Use Building with Live-Work Layout

3236 National Ave, San Diego, CA 92113

$979,000
1,730 sqft

Commercial space occupies the lower level, with shopkeeper quarters above.

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Ground-Floor Office Condo Suite
Ground-Floor Office Condo Suite

3740 Park Boulevard Cu1, San Diego, CA 92103

$2,100,000
2,360 sqft

Modern ground-floor office condo built in 2007 with private offices, reception, open work areas, and multiple entrances.

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Office Building with Covered Patio
Office Building with Covered Patio

2419 El Cajon, San Diego, CA 92104

$2,500,000
0.16 AC lot

An open-plan interior pairs gallery and work areas with a glass conference room and sheltered outdoor space.

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Kearny Mesa Multi-Tenant Office Building
Kearny Mesa Multi-Tenant Office Building

4565 Ruffner St, San Diego, CA 92111

$4,750,000
15,974 sqft

Two-story office building near Convoy Street, fully occupied by 27 tenants.

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Office Building for Sale
Office Building for Sale

1541 8th Ave, San Diego, CA 92101

$5,250,000
11,400 sqft

For-sale office property located at 1541 8th Avenue in San Diego, CA.

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Four-Story Medical Office Building
Four-Story Medical Office Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

Contact for pricing
4,266 sqft 3.05 AC lot

Four-story medical office building on 3.05 acres with elevators, central courtyard, and ample surface and covered parking.

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Flex Building with Roll-Up Doors
Flex Building with Roll-Up Doors

9173 Sky Park Court, San Diego, CA 92123

Contact for pricing
26,036 sqft 1.83 AC lot

Climate-controlled space includes three-phase electrical service and glass-enclosed roll-up door positions.

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Corner-Lot Mixed-Use Building
Corner-Lot Mixed-Use Building

2754 Imperial Avenue, San Diego, CA 92102

Contact for pricing
4,272 sqft 0.13 AC lot

Private offices, four restrooms, a kitchenette, and on-site parking accommodate flexible commercial occupancy.

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Mixed-Use Property with Residence
Mixed-Use Property with Residence

4741 Point Loma Ave, San Diego, CA 92106

Contact for pricing
3,376 sqft

Three-part configuration combines commercial suites with a two-level upper residence.

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Commercial Office Property
Commercial Office Property

8430 Juniper Creek Ln, San Diego, CA 92126

Contact for pricing
8,571 sqft

CO-1-1 zoning supports employment uses with limited complementary retail and medium- to high-density residential development.

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Flex Facility with Laboratory Space
Flex Facility with Laboratory Space

9292 Chesapeake Drive, San Diego, CA 92123

Contact for pricing
6,500 sqft 0.50 AC lot

A single site combines administrative, research, and garage functions in one building.

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