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    San Diego, CA Mixed-use Properties for Sale

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    Mixed-Use Property with Commercial Building
    Updated: Sep 25
    Mixed-Use Property with Commercial Building

    2971 Imperial Ave, San Diego, CA 92102

    $1,080,000
    1,775 sqft 0.13 AC lot
    Detached residence: approximately 1,050 square feet, 3 bedrooms and 2.5 bathrooms
    Separate commercial building of approximately 700 square feet facing Imperial Ave
    Approximately 5,600‑square‑foot lot zoned CN‑1‑3
    Tier 3 area with potential for up to 6.5 FAR for qualifying projects
    Gated driveway with alley access and parking for 6+ vehicles
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    Three-Story Mixed-Use Building
    Updated: Mar 11
    Three-Story Mixed-Use Building

    2368 2nd AVE, San Diego, CA 92101

    $2,669,000
    3,800 sqft 0.13 AC lot
    3‑story mixed‑use building with approximately 3,800 square feet
    0.1251‑acre parcel at 2368 2nd AVE, San Diego, CA 92101
    Independent access to each floor supports separate occupancy or leasing
    Mixed‑use zoning accommodates commercial and residential configurations
    Mills Act property with tax benefits for qualified owners
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    Upgraded Mixed-Use Property
    Upgraded Mixed-Use Property

    110 Maple, San Diego, CA 92103

    $4,890,000
    3,750 sqft 0.13 AC lot

    Five-unit corner asset combines professional office space with remodeled residential units and shared landscaped courtyard.

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    See hot listings in San Diego

    Scored against comparables nationwide. These are worth a look.

    Scored against comparables nationwide. These are worth a look.

    Cap Rate available after sign in
    Est. NOI available after sign in
    Local Demand available after sign in
    Updated Mixed-Use Office-Retail Building
    Updated Mixed-Use Office-Retail Building

    3675 Voltaire St, San Diego, CA 92106

    $4,500,000
    11,060 sqft

    Retail space at grade is paired with offices above in a flexible commercial layout.

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    Mixed-Use Storefront Property
    Mixed-Use Storefront Property

    3275 Euclid, San Diego, CA 92105

    $900,000
    0.11 AC lot

    Corner-lot commercial property with storefront space and separate entrances.

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    Live-Work Space with Two Offices
    Live-Work Space with Two Offices

    2487 Kettner Blvd, San Diego, CA 92101

    $1,149,000
    1,610 sqft 0.02 AC lot

    Commercially zoned property with two kitchens, an upgraded full bath, and mixed-use flexibility for office or residential use.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Four-Story Mixed-Use Building
    Four-Story Mixed-Use Building

    920 Kline Street, La Jolla, CA 92037

    $5,800,000
    20,000 sqft 1.50 AC lot

    Mixed retail and office occupancy is supported by an updated elevator and private baths in many suites.

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    Mixed-Use Property with Alley Access
    Mixed-Use Property with Alley Access

    1434-44 Garnet Ave, San Diego, CA 92109

    $1,850,000
    1,622 sqft 0.14 AC lot

    Retail/office space includes a detached studio and rear open area.

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    Bankers Hill Mixed-Use Opportunity
    Bankers Hill Mixed-Use Opportunity

    2368 2nd Ave, San Diego, CA 92101

    $2,669,000
    3,800 sqft

    Three-story mixed-use property in Bankers Hill near Balboa Park.

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    Corner-Lot Mixed-Use Building
    Corner-Lot Mixed-Use Building

    2754 Imperial Avenue, San Diego, CA 92102

    Contact for pricing
    4,272 sqft 0.13 AC lot

    Private offices, four restrooms, a kitchenette, and on-site parking accommodate flexible commercial occupancy.

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    Mixed-Use Property with Residence
    Mixed-Use Property with Residence

    4741 Point Loma Ave, San Diego, CA 92106

    Contact for pricing
    3,376 sqft

    Three-part configuration combines commercial suites with a two-level upper residence.

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    Signalized Corner Mixed-Use Property
    Signalized Corner Mixed-Use Property

    1075 ROSECRANS ST SAN DIEGO CA 92106-3044, San Diego, CA 92106

    Contact for pricing
    4,209 sqft 0.22 AC lot

    CC 4-2 zoning supports retail, office, residential, and hospitality applications.

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    Single-Tenant Mixed-Use Building
    Single-Tenant Mixed-Use Building

    2317 Hotel Circle South, San Diego, CA 92108

    Contact for pricing
    9,240 sqft 1.86 AC lot

    Two-story retail and office asset with CO-2-2 zoning and on-site parking.

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    Freestanding Mixed-Use Lab Building
    Freestanding Mixed-Use Lab Building

    9955 Mesa Rim Rd, San Diego, CA 92121

    Contact for pricing
    15,853 sqft 5.45 AC lot

    Renovation plans include facade and landscaping upgrades, with warehouse and laboratory infrastructure already in place.

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    Renovated Mixed-Use Portfolio
    Renovated Mixed-Use Portfolio

    3131-57 Adams Avenue, San Diego, CA 92116

    Contact for pricing
    7,520 sqft 0.35 AC lot

    Two adjacent properties combine apartments, retail suites, and updated residential interiors.

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    Mixed-Use Building with Residential Units
    Mixed-Use Building with Residential Units

    4702-4714 University Ave, San Diego, CA 92105

    Contact for pricing
    11,517 sqft 0.45 AC lot

    Mixed-use improvements include four vacant one-bedroom, one-bath residential units.

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    Mixed-Use Investment in La Playa
    Mixed-Use Investment in La Playa

    1051-65 Rosecrans Street, San Diego, CA 92106

    Contact for pricing
    7,600 sqft

    Mixed-use property in Point Loma with retail and residential units.

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    Mixed-Use Development Opportunity
    Mixed-Use Development Opportunity

    2135 University Avenue, San Diego, CA 92104

    Contact for pricing
    880 sqft

    Current automotive repair shop in San Diego’s Transit Priority Zone, with plans outlined for retail below and multifamily above.

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    Three-Building Mixed-Use Property
    Three-Building Mixed-Use Property

    2329 India Street, San Diego, CA 92101

    Contact for pricing
    4,274 sqft

    Mixed-use offering with three separate buildings and on-site parking stalls for operational flexibility.

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    Corner Lot with Development Potential
    Corner Lot with Development Potential

    3665 Imperial Ave, San Diego, CA 92113

    $624,000
    0.14 AC lot

    High-traffic corner lot suitable for commercial or residential development.

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    Mixed-Use Building with Loft
    Mixed-Use Building with Loft

    1733-37 Adams Ave, San Diego, CA 92116

    $1,200,000

    Existing café space includes a grease trap and an upper-level loft.

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    Downtown San Diego Mixed-Use Building
    Downtown San Diego Mixed-Use Building

    640 Broadway, San Diego, CA 92101

    Contact for pricing
    29,096 sqft 0.23 AC lot

    Mixed-use building in downtown San Diego with redevelopment potential.

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    Remodeled Mixed-Use Property
    Remodeled Mixed-Use Property

    110 Maple, San Diego, CA 92103

    $4,890,000
    3,750 sqft

    Corner asset combining professional office space with four updated residential units and a shared landscaped courtyard.

    View details
    Mixed-Use Property with Development Plans
    Mixed-Use Property with Development Plans

    3659 Adams Ave, San Diego, CA 92116

    $1,900,000

    An existing commercial space and planned residential units create a mixed-use configuration on Adams Avenue.

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    San Diego, CA Mixed-Use Properties Market Trends and Statistics

    Explore 49 mixed-use properties for sale in San Diego, CA, showcased through 39 active listings on our real estate platform. These investment opportunities span a total of 245,121 square feet of properties for sale, with an estimated market value of $51,665,000.

    Sale prices for multi use buildings in San Diego, CA start at $624,000, averaging $2,870,277, and reaching up to $5,800,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Live-work space 11

    Demographics Overview

    Population 1.38M
    Population Growth (5Y) -2.1%
    Median Household Income $109,172
    College Educated 31.4%

    High-Yield Neighborhoods for Investment

    Identify San Diego submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    92113 $1.1M
    92105 $1.8M
    92114 $1.9M
    92101 $2.4M
    92103 $4.2M

    Taxes & Financing

    Tax Rate (average for all types) 1.17%
    Property Tax per SF $13.93 per SF
    Tax Rate vs County Average 0.03 pp below county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in San Diego County

    New Delisted

    Total CRE Inventory on Market (SF)

    Property Size Breakdown

    The majority of commercial real estate listings in San Diego fall within the 100,000+ square foot range.

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    Browse Mixed-use properties for Sale Near San Diego, CA

    Popular Searches in San Diego, CA

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    Most Searched ZIP Codes in San Diego, CA

    • 92101
    • 92103
    • 92106
    • 92037
    • 92102
    • 92105
    • 92116
    • 92107
    • 92109
    • 33713
    • 92104
    • 92108

    Featured San Diego Real Estate Agencies

    Realmo connects you with licensed San Diego CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Century 21 Horizon
    4134 Adams Ave., #101 San Diego, CA 92116
    Phone: 16192805888
    www.century21horizon.com
    Hacienda Realty
    4683 Pt. Loma Ave. San Diego, CA 92107
    Phone: 16194174493
    www.haciendasd.com

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