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    San Diego, CA Mixed-use Properties for Sale

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    Coronado, CA National City, CA Chula Vista, CA
    32 results
    Bankers Hill Mixed-Use Opportunity
    $2,849,000
    3,800 SF

    Bankers Hill Mixed-Use Opportunity

    2368 2nd AVE, San Diego, CA 92101

    Three-story mixed-use building in Bankers Hill with flexible zoning.

    • Prime location at the intersection of Bankers Hill, Balboa Park, and the Airport.
    • Flexible Mixed‑Use zoning allows for a wide range of possibilities.
    • Historic designation adds unique appeal and potential benefits.
    • Onsite parking is available.
    • Independently accessible floors with private entrances/exits enable simultaneous leasing, operation, and occupancy for multiple income streams.
    Updated: Feb 26
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    San Ysidro Mixed-Use Investment Opportunity
    $4,099,000
    7,989 SF

    San Ysidro Mixed-Use Investment Opportunity

    165 W San Ysidro Blvd, San Ysidro, CA 92173

    New 7-unit mixed-use property near U.S.-Mexico border.

    • Prime location: Just 1.5 miles from the world's busiest land border crossing.
    • New construction (2021) offers 7 units with 7,989 SF of rentable space.
    • Mixed‑use zoning (CC‑3‑4) provides flexible options for restaurants, medical offices, or professional services.
    • Benefit from 20 on‑site parking spaces.
    • Equipped with grease interceptors and elevator service.
    Updated: Apr 4
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    Mixed-Use Property Near Downtown
    $850,000

    Mixed-Use Property Near Downtown

    Mixed-use investment property near Downtown San Diego and Petco Park.

    2557-59 Imperial Ave, San Diego, CA 92102
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    Remodeled Mixed-Use Property in Hillcrest
    $1,189,000
    1,778 SF

    Remodeled Mixed-Use Property in Hillcrest

    Remodeled office and retail space in dynamic Hillcrest neighborhood.

    825-829 Washington St., San Diego, CA 92103
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    Versatile Mixed-Use Commercial Property
    $1,149,000
    1,610 SF

    Versatile Mixed-Use Commercial Property

    Mixed-use property with office spaces and potential live/work loft.

    2487 Kettner Blvd, San Diego, CA 92101
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    Mixed-Use Development Opportunity, San Diego
    $1,890,000
    4,569 SF

    Mixed-Use Development Opportunity, San Diego

    Mixed-use development site with income potential in up-and-coming Encanto.

    6365 Imperial Avenue, San Diego, CA 92114
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    Landmark Multifamily Investment Opportunity
    $4,995,000
    5,506 SF

    Landmark Multifamily Investment Opportunity

    Signature income property in prime San Diego location.

    3574 4th Ave. (-80), San Diego, CA 92103
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    Downtown San Diego Mixed-Use Building
    $7,900,000
    29,096 SF

    Downtown San Diego Mixed-Use Building

    Mixed-use building in downtown San Diego with redevelopment potential.

    640 Broadway, San Diego, CA 92101
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    Downtown San Diego Corner Unit
    $1,149,900

    Downtown San Diego Corner Unit

    Versatile corner unit in vibrant East Village, San Diego.

    875 G St, San Diego, CA 92101
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    Rebuilt Mixed-Use Investment Property
    $4,495,000
    3,360 SF

    Rebuilt Mixed-Use Investment Property

    Rebuilt 2025 mixed-use property in North Park's Adams Corridor.

    2611 Adams Ave, San Diego, CA 92116
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    Bankers Hill Mixed-Use Opportunity
    $2,849,000
    3,800 SF

    Bankers Hill Mixed-Use Opportunity

    Three-story mixed-use property in Bankers Hill near Balboa Park.

    2368 2nd AVE, San Diego, CA 92101
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    Mixed-Use Property on El Cajon
    $3,500,000

    Mixed-Use Property on El Cajon

    Mixed-use property in growing North Park area.

    2144 El Cajon Blvd, San Diego, CA 92104
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    La Jolla Multifamily Redevelopment Opportunity
    $2,500,000

    La Jolla Multifamily Redevelopment Opportunity

    Multifamily property redevelopment site in prime La Jolla location.

    7421 La Jolla Blvd., San Diego, CA 92037
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    Mixed-Use Property in Downtown San Diego
    $2,500,000

    Mixed-Use Property in Downtown San Diego

    Fully occupied mixed-use property with residential and commercial units.

    1041 6th Ave, San Diego, CA 92101
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    Mixed-Use Investment Golden Hill Location
    $1,750,000

    Mixed-Use Investment Golden Hill Location

    Mixed-use property in Golden Hill with residential and retail income.

    1232 30th St, San Diego, CA 92102
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    North Park Mixed-Use Investment Property
    $4,495,000
    3,360 SF

    North Park Mixed-Use Investment Property

    Rebuilt mixed-use property with restaurant and luxury boutique suites.

    2611 Adams Ave, San Diego, CA 92116
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    Bankers Hill Mixed-Use Opportunity
    $2,849,000
    3,800 SF

    Bankers Hill Mixed-Use Opportunity

    Three-story mixed-use building in Bankers Hill with flexible zoning.

    2368 2nd Ave, San Diego, CA 92101
    View details
    San Diego Mixed-Use Development Site
    Contact for pricing
    31,000 SF

    San Diego Mixed-Use Development Site

    1.26-acre property suitable for mixed commercial/residential uses.

    1895 Hancock St, San Diego, CA
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    Mixed-Use Property in Downtown San Diego
    $2,500,000
    10,866 SF

    Mixed-Use Property in Downtown San Diego

    Fully occupied mixed-use property with residential and commercial units.

    1041 Sixth Ave, San Diego, CA 92101
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    Mixed-Use Property in San Diego
    Contact for pricing

    Mixed-Use Property in San Diego

    Mixed-use property available for sale in San Diego, California.

    3730 5th Ave., San Diego, CA 92103
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    Mixed-Use Golden Hill Investment
    $1,900,000
    4,276 SF

    Mixed-Use Golden Hill Investment

    Mixed-use property in Golden Hill with residential and retail income.

    1232-36 30th St, San Diego, CA 92102
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    Barrio Logan Redevelopment Opportunity
    $2,300,000
    6,742 SF

    Barrio Logan Redevelopment Opportunity

    Mixed-use redevelopment opportunity in the heart of Barrio Logan.

    2186-90 National Ave, San Diego, CA 92113
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    High Traffic Corner Location
    $649,000
    0.15 Acres

    High Traffic Corner Location

    Corner lot with live-work space and yard.

    3665 Imperial Ave, San Diego, CA 92113
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    Remodeled Mixed-Use Property in Hillcrest
    $1,189,000
    1,778 SF

    Remodeled Mixed-Use Property in Hillcrest

    Remodeled office and retail space in dynamic Hillcrest neighborhood.

    825-829 Washington St., San Diego, CA 92103
    View details

    San Diego, CA Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 42 mixed-use properties for sale in San Diego, CA, showcased through 32 active listings on our real estate platform. These investment opportunities span a total of 143,702 square feet of properties for sale, with an estimated market value of $81,761,000.

    Sale prices for multi use buildings in San Diego, CA start at $1,189,000, averaging $4,303,210, and reaching up to $11,800,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Live-work space 13

    Property Size Breakdown

    The majority of commercial real estate listings in San Diego fall within the 100,000+ square foot range.

    Demographics Overview

    Population 1.38M
    Population Growth (5Y) -2.1%
    Median Household Income $109,172
    College Educated 31.4%

    High-Yield Neighborhoods for Strategic Investment

    Identify San Diego submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    La Jolla $2.5M
    San Diego $3.7M

    Taxes & Financing

    Tax Rate (average for all types) 1.17%
    Property Tax per SF $13.93 per sq ft
    Tax Rate vs County Average 0.03 pp below county avg
    Average Loan-to-Value 65.0%

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