San Diego, CA Commercial real estate for sale

Updated: Sep 25

Mixed-Use Property with Residence

2971 Imperial Avenue, San Diego, CA 92102

$1,080,000

1,775 sqft 0.13 AC lot

Remodeled detached residence with 3 bedrooms and 2.5 bathrooms
Separate commercial building faces Imperial Avenue
Approximately 5,600‑square‑foot lot zoned CN‑1‑3
Complete Communities Housing Solutions Tier 3 area; qualifying projects may offer up to 6.5 FAR
Covered patio and gated driveway with alley access

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Updated: Sep 10

Multifamily Property With Detached Units

4159 38th St, San Diego, CA 92105

$999,000

1,386 sqft 0.08 AC lot

Three detached living spaces on a 0.0804‑acre lot
1,386 square feet with 3 bedrooms, 1.5 bathrooms, and in‑unit laundry in the primary residence
Additional dwellings include 1 bedroom and 1 bathroom each
RM‑2‑5 zoning
Built in 1926 with a composition roof

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26-Unit Apartment Building

4017 42nd St, San Diego, CA 92105

$8,995,000

9,112 sqft

A master NNN lease with a nonprofit operator is in place.

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Scored against comparables nationwide. These are worth a look.

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Office Building with Covered Patio

2419 El Cajon, San Diego, CA 92104

$2,500,000

5,000 sqft 0.16 AC lot

An existing architectural office pairs open work areas and a glass-walled conference room with outdoor space beneath a pergola.

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Office Building with Covered Patio

2419 El Cajon, San Diego, CA 92104

$2,500,000

0.16 AC lot

An open-plan interior pairs gallery and work areas with a glass conference room and sheltered outdoor space.

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Mixed-Use Building with Retail Space

3580 Adams Ave, San Diego, CA 92116

$2,600,000

3,690 sqft 0.15 AC lot

Retail space and five apartments share the property, with alley access and on-site parking.

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Mixed-Use Storefront Property

3275 Euclid, San Diego, CA 92105

$900,000

0.11 AC lot

Corner-lot commercial property with storefront space and separate entrances.

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Penthouse Office Suite

1350 Columbia St, San Diego, CA 92101

$3,875,000

6,678 sqft

The ninth-floor workspace includes collaborative seating, a glass-enclosed conference room, phone pods, and a hospitality bar.

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Upgraded Mixed-Use Property

110 Maple, San Diego, CA 92103

$4,810,000

3,750 sqft 0.13 AC lot

Five-unit corner asset combines professional office space with remodeled residential units and shared landscaped courtyard.

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Remodeled 4-Unit Quadplex

6979-85 Lisbon St, San Diego, CA 92114

$1,450,000

0.09 AC lot

All four residences are occupied and professionally managed, with remodeled interiors and central heating and air conditioning.

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Mixed-Use Property with Residence

2971 Imperial Ave, San Diego, CA 92102

$1,080,000

700 sqft 0.13 AC lot

A detached home and separate Imperial Ave commercial building occupy a gated site with alley access.

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Live-Work Space with Two Offices

2487 Kettner Blvd, San Diego, CA 92101

$1,149,000

1,610 sqft 0.02 AC lot

Commercially zoned property with two kitchens, an upgraded full bath, and mixed-use flexibility for office or residential use.

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Commercial Infill Land Parcel

47th St, San Diego, CA 92102

$450,000

0.14 AC lot

Vacant commercial-zoned parcel with existing curbs and access to surrounding neighborhoods, businesses, and major roadways.

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Auto Repair Shop with Equipment

301 16th St, San Diego, CA 92101

$1,492,000

1,926 sqft 0.10 AC lot

The existing automotive service setup includes repair equipment, three-phase power, and on-site parking.

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Freestanding Office Building with Parking

6334 University Avenue, San Diego, CA 92115

$950,000

Freestanding office building operating as a mortuary, with chapel/viewing space and rear access plus on-site parking.

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Dry-Cleaning Storefront Business

1031 Market Street, San Diego, CA 92101

$250,000

Operating dry-cleaning business with established customers, transferable permits, and leased locations.

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Freestanding Office Building

4394 30th, San Diego, CA 92104

$1,649,000

1,735 sqft 0.07 AC lot

Five private offices, a conference room, reception area, kitchen, and two restrooms support a functional workplace layout.

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Flex Space with Loading Dock

3065 Beyer Boulevard, San Diego, CA 92154

$1,990,000

Flexible industrial space includes office reception, central air, and rear loading access.

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Mixed-Use Building with Storefront

4741 Point Loma, San Diego, CA 92107

$2,295,000

3,376 sqft

Two commercial spaces occupy the lower level, with a four-bedroom residence above.

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Two-Structure Flex Property

3946 La Salle St, San Diego, CA 92110

$1,500,000

Street-facing retail or office space is paired with an open shop area for flexible commercial use.

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Freestanding Office Building

5050 Federal Boulevard, San Diego, CA 92102

$3,300,000

9,930 sqft 0.58 AC lot

Renovated commercial office property with flexible rooms, accessible facilities, gated parking, and an adjoining apartment.

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Second-Floor Office Units

7060 Miramar Rd, San Diego, CA 92121

Contact for pricing

Two updated suites provide flexible layouts within a shopping center with shared restrooms, monument signage, and on-site parking.

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Freestanding Office Building

6334 University Ave, San Diego, CA 92115

$950,000

2,273 sqft

Functional office configuration with reception areas, private rooms, monument signage, rear access, and on-site parking.

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Retail Showroom Suite

7050 Miramar, San Diego, CA 92121

Contact for pricing

Front-facing retail space with showroom presentation, monument signage, and parking at Miramar Crossings.

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San Diego, CA Commercial Real Estate Market Trends and Statistics

Explore 330 commercial real estate for sale in San Diego, CA, showcased through 330 active listings on our real estate platform. These investment opportunities span a total of 3,041,729 square feet of properties for sale, with an estimated market value of $411,799,174.

Sale prices for business properties in San Diego, CA start at $75,000, averaging $3,431,659, and reaching up to $42,220,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

San Diego, CA CRE market trends — vacancy, lease rates and price per SF, updated monthly

Neighborhood	Average Price
Vista - 92084	$850K
National City - 91950	$1.9M
La Jolla - 92037	$2.5M
San Diego - 92101	$2.8M
San Ysidro - 92173	$7.6M

Neighborhood

Average Price

Vista - 92084

$850K

National City - 91950

$1.9M

La Jolla - 92037

$2.5M

San Diego - 92101

$2.8M

San Ysidro - 92173

$7.6M