Mixed-Use

San Diego, CA Mixed-use Properties for Lease

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Coronado, CA National City, CA Chula Vista, CA Lemon Grove, CA La Mesa, CA Spring Valley, CA Bonita, CA Vista, CA
Renovated Live-Work Space
Updated: Sep 7
Renovated Live-Work Space

4741 Point Loma, San Diego, CA 92106

$12,000/Mo
1,626 SF of ground‑floor commercial space in two connected areas
1,750 square foot residence with four bedrooms, two baths, ocean views, and a private deck
613 square feet of finished storefront plus a 263 square foot covered breezeway
750 square feet of open flex space with a roll‑up door for alley loading
Built 2016 with ADA‑compliant features and dedicated on‑site parking
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San Diego Commercial Space Available
Updated: Mar 26
San Diego Commercial Space Available

9360-9420 Activity Rd., San Diego, CA 92126

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8,472 sqft
For Lease
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San Diego Commercial Space For Lease
San Diego Commercial Space For Lease

17066 Goldentop Rd., San Diego, CA 92127

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Mixed-use, retail, office, and industrial spaces available for lease.

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Gaslamp City Square Retail Space
Gaslamp City Square Retail Space

425-445 Island Ave, San Diego, CA

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3,333 sqft 0.83 AC lot

Mixed-use property in the heart of San Diego's Gaslamp Quarter.

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Based on your search, we've compiled 48 Potential Opportunities for your consideration. Besides 4 Active listings in San Diego, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 40 Properties for Sales.

Mixed-use properties for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Mixed-Use Property with Office Space
Mixed-Use Property with Office Space

25275 Jefferson, Murrieta, CA 92562

$9,500/Mo
3,031 sqft 4.00 AC lot

Leasable commercial property combining remodeled offices with warehouse, shed, and additional living space.

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Mixed-Use Suites with Buildout Options
Mixed-Use Suites with Buildout Options

1931 E Florida Ave, Hemet, CA 92544

$2,331/Mo

Leasing opportunities include office, retail, and studio suites with customizable interior buildouts.

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Shopping Center Retail Suites
Shopping Center Retail Suites

1927 E florida, Hemet, CA 92544

$2,331/Mo

Office, studio, and storefront configurations are offered with buildout options for businesses seeking dedicated commercial space.

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Ground-Floor Retail Suites with Patio
Ground-Floor Retail Suites with Patio

24610 Washington Ave, Murrieta, CA 92562

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13,571 sqft

New mixed-use retail suites offer flexible sizes for food, service, and street-oriented businesses with potential patio use.

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Similar Spaces for Sale in San Diego, CA

Consider Similar Space for Sale. We found 40 Spaces matching your search parameters.

Mixed-Use Property with Commercial Building
Mixed-Use Property with Commercial Building

2971 Imperial Ave, San Diego, CA 92102

$1,080,000
1,775 sqft 0.13 AC lot

A remodeled residence and a separate business space occupy a gated site with alley access and on-site parking.

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Updated Mixed-Use Office-Retail Building
Updated Mixed-Use Office-Retail Building

3675 Voltaire St, San Diego, CA 92106

$4,500,000
11,060 sqft

Retail space at grade is paired with offices above in a flexible commercial layout.

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Three-Story Mixed-Use Building
Three-Story Mixed-Use Building

2368 2nd AVE, San Diego, CA 92101

$2,669,000
3,800 sqft 0.13 AC lot

Flexible mixed-use property with separately accessible levels, on-site parking, and a Mills Act designation.

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Four-Story Mixed-Use Building
Four-Story Mixed-Use Building

920 Kline Street, La Jolla, CA 92037

$5,800,000
20,000 sqft 1.50 AC lot

Mixed retail and office occupancy is supported by an updated elevator and private baths in many suites.

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Bankers Hill Mixed-Use Opportunity
Bankers Hill Mixed-Use Opportunity

2368 2nd Ave, San Diego, CA 92101

$2,669,000
3,800 sqft

Three-story mixed-use property in Bankers Hill near Balboa Park.

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Mixed-Use Property with Alley Access
Mixed-Use Property with Alley Access

1434-44 Garnet Ave, San Diego, CA 92109

$1,995,000
1,622 sqft 0.14 AC lot

Retail/office space includes a detached studio and rear open area.

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Upgraded Mixed-Use Property
Upgraded Mixed-Use Property

110 Maple, San Diego, CA 92103

$4,890,000
3,750 sqft 0.13 AC lot

Five-unit corner asset combines professional office space with remodeled residential units and shared landscaped courtyard.

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Two-Unit Duplex with Parking Pad
Two-Unit Duplex with Parking Pad

3314 E St, San Diego, CA 92102

$849,900
1,354 sqft

Mixed-use zoning accompanies two separately addressed one-bedroom residences.

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Mixed-Use Storefront Property
Mixed-Use Storefront Property

3275 Euclid, San Diego, CA 92105

$900,000
0.11 AC lot

Corner-lot commercial property with storefront space and separate entrances.

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Corner-Lot Mixed-Use Building
Corner-Lot Mixed-Use Building

2754 Imperial Avenue, San Diego, CA 92102

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4,272 sqft 0.13 AC lot

Private offices, four restrooms, a kitchenette, and on-site parking accommodate flexible commercial occupancy.

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Mixed-Use Property with Residence
Mixed-Use Property with Residence

4741 Point Loma Ave, San Diego, CA 92106

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3,376 sqft

Three-part configuration combines commercial suites with a two-level upper residence.

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Signalized Corner Mixed-Use Property
Signalized Corner Mixed-Use Property

1075 ROSECRANS ST SAN DIEGO CA 92106-3044, San Diego, CA 92106

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4,209 sqft 0.22 AC lot

CC 4-2 zoning supports retail, office, residential, and hospitality applications.

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Single-Tenant Mixed-Use Building
Single-Tenant Mixed-Use Building

2317 Hotel Circle South, San Diego, CA 92108

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9,240 sqft 1.86 AC lot

Two-story retail and office asset with CO-2-2 zoning and on-site parking.

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Mixed-Use Property with Rear Access
Mixed-Use Property with Rear Access

3590 5th Ave, San Diego, CA 92103

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2,649 sqft

Flexible commercial space combines office and retail functionality with private-lot delivery access and exposure along 5th Ave.

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Live-Work Space with Two Offices
Live-Work Space with Two Offices

2487 Kettner Blvd, San Diego, CA 92101

$1,149,000
1,610 sqft 0.02 AC lot

Commercially zoned property with two kitchens, an upgraded full bath, and mixed-use flexibility for office or residential use.

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Freestanding Mixed-Use Lab Building
Freestanding Mixed-Use Lab Building

9955 Mesa Rim Rd, San Diego, CA 92121

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15,853 sqft 5.45 AC lot

Renovation plans include facade and landscaping upgrades, with warehouse and laboratory infrastructure already in place.

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Renovated Mixed-Use Portfolio
Renovated Mixed-Use Portfolio

3131-57 Adams Avenue, San Diego, CA 92116

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7,520 sqft 0.35 AC lot

Two adjacent properties combine apartments, retail suites, and updated residential interiors.

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Mixed-Use Building with Residential Units
Mixed-Use Building with Residential Units

4702-4714 University Ave, San Diego, CA 92105

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11,517 sqft 0.45 AC lot

Mixed-use improvements include four vacant one-bedroom, one-bath residential units.

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Mixed-Use Investment in La Playa
Mixed-Use Investment in La Playa

1051-65 Rosecrans Street, San Diego, CA 92106

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7,600 sqft

Mixed-use property in Point Loma with retail and residential units.

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Mixed-Use Development Opportunity
Mixed-Use Development Opportunity

2135 University Avenue, San Diego, CA 92104

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880 sqft

Current automotive repair shop in San Diego’s Transit Priority Zone, with plans outlined for retail below and multifamily above.

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San Diego, CA Mixed-use properties Lease Rates & Market Statistics

Explore 4 Mixed-use properties for lease in San Diego, CA on Realmo, a commercial real estate exchange covering the San Diego area. The current inventory totals 11,805 square feet of properties.

Mixed-use properties lease rates in San Diego range from $12,000/Mo at the entry level to $12,000/Mo at the top of the market, averaging $12,000/Mo. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings.

San Diego accounts for 40% of the 10 mixed-use properties currently available across San Diego County, where nearby markets include Carlsbad and Chula Vista.

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