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    San Diego, CA Medical Office Space for Sale

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    Coronado, CA National City, CA Lemon Grove, CA Chula Vista, CA La Mesa, CA Spring Valley, CA Imperial Beach, CA Bonita, CA
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    San Ysidro Mixed-Use Investment Opportunity
    Updated: Apr 4
    San Ysidro Mixed-Use Investment Opportunity

    165 W San Ysidro Blvd, San Ysidro, CA 92173

    $4,099,000
    7,989 sqft 0.32 AC lot
    Prime location: Just 1.5 miles from the world's busiest land border crossing.
    New construction (2021) offers 7 units with 7,989 SF of rentable space.
    Mixed‑use zoning (CC‑3‑4) provides flexible options for restaurants, medical offices, or professional services.
    Benefit from 20 on‑site parking spaces.
    Equipped with grease interceptors and elevator service.
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    This listing looks promising.

    Here's a quick look at some key insights for

    165 W San Ysidro Blvd, San Ysidro, CA 92173

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    • Est. Cap Rate

      4.7%
      NOI ÷ price

    • Est. NOI

      $193K
      Annual

    • Mortgage

      $2.4M
      Apr 2025

    • Last Sold

      Nov 2012
      $950K

    • Property Type

      Retail Stores
      Built 2021
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    Mixed-Use Corner Commercial Property
    Updated: Jul 6
    Mixed-Use Corner Commercial Property

    3275 Euclid, San Diego, CA 92105

    $900,000
    0.11 AC lot
    Zoned CUPD‑CU‑1‑1 within San Diego’s Central Urbanized Planned District for a mixed‑use concept
    1,380 SF property on a 4,802 SF corner lot along a high‑traffic transit corridor
    Dual‑address identity: 3275 Euclid Ave & 4769 Thorn St, with separate entrances for business operations and residential/private access
    Located in the protected Islenair Historic District (buyer to verify historic guidelines with the City of San Diego)
    Commercial storefront on the property with street visibility for storefront signage
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    Mixed-Use Property in Opportunity Zone
    Mixed-Use Property in Opportunity Zone

    4170 Fairmount Ave, San Diego, CA 92105

    $999,000
    1,404 sqft

    Mixed-use property with high foot traffic in City Heights.

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    Ground-Floor Office/Medical Condo
    Ground-Floor Office/Medical Condo

    3740 Park Boulevard Unit CU1, San Diego, CA 92103

    $2,100,000
    2,360 sqft

    Ground-floor condo in the DECA building offers private offices, reception space, and multiple entrances with eight dedicated parking spaces.

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    Ground-Floor Office Condo Suite
    Ground-Floor Office Condo Suite

    3740 Park Boulevard Cu1, San Diego, CA 92103

    $2,100,000
    2,360 sqft

    Modern ground-floor office condo built in 2007 with private offices, reception, open work areas, and multiple entrances.

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    Medical Office Condominium Building
    Medical Office Condominium Building

    11770 Bernardo Plaza Ct, San Diego, CA 92128

    $1,469,182
    2,366 sqft 3.05 AC lot

    Well-maintained four-story medical office building with upgraded interiors and common areas, positioned for healthcare operators.

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    Second-Floor Office Condominium Suite
    Second-Floor Office Condominium Suite

    8947 Complex Dr, San Diego, CA 92123

    $550,000
    1,393 sqft

    Vacant second-floor office suite with new floors, dual balconies, reception, four offices, and kitchenette area.

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    Office/Medical Condominium Project in San Diego
    Office/Medical Condominium Project in San Diego

    5080-90 Shoreham Pl, San Diego, CA 92122

    Contact for pricing
    6,549 sqft

    Two-story office/medical condominium project in Governor Park, San Diego.

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    Medical Office Suites For Sale
    Medical Office Suites For Sale

    11717 Bernardo Plaza Ct, San Diego, CA 92128

    Contact for pricing
    7,200 sqft

    Modern, renovated medical office suites in Rancho Bernardo.

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    La Jolla Multifamily/Medical Building
    La Jolla Multifamily/Medical Building

    6628 La Jolla Blvd., San Diego, CA 92037

    $2,800,000

    Multifamily property with RM-7 zoning, suitable for medical building.

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    Medical/Office Building For Sale
    Medical/Office Building For Sale

    8933 Activity Rd, San Diego, CA

    Contact for pricing
    36,731 sqft 1.84 AC lot

    Mixed-use building suitable for owner-user or multiple tenants.

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    Chiropractic Medical Office Business
    Chiropractic Medical Office Business

    4223 Genesee Ave # 110, San Diego, CA 92117

    $489,000

    Profitable, fully staffed chiropractic business under a national franchise, offered as one or two locations with NDA.

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    Mixed-Use Office and Retail Building
    Mixed-Use Office and Retail Building

    4116 W Point Loma Blvd, San Diego, CA 92110

    $2,800,000

    In-place office and retail property with a medical lease set to expire in January 2027.

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    San Diego Medical/Office Condo
    San Diego Medical/Office Condo

    5330 Carroll Canyon Rd, San Diego, CA 92121

    Contact for pricing
    4,314 sqft

    Spacious condo ideal for medical or office use.

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    Fully Leased Medical Office Building
    Fully Leased Medical Office Building

    306-16 25th Street, San Diego, CA 92102

    Contact for pricing

    Two tenant units include a long-term medical clinic and a hair salon, with a 9-space parking lot.

    View details
    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 15 Active listings in San Diego, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 57 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Medical Office Corner Suite
    Medical Office Corner Suite

    15525 Pomerado Road, Suite C-5, Poway, CA 92064

    $500,000
    861 sqft

    Second-floor corner suite with natural lighting and elevator service, adjacent to imaging and surgery center space.

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    Renovated Medical/Professional Building For Sale
    Renovated Medical/Professional Building For Sale

    15644 Pomerado Rd, Poway, CA 92064

    $855,000
    1,368 sqft

    Renovated medical/professional building near Pomerado Hospital with high visibility.

    View details
    Atrium-Style Office Building
    Atrium-Style Office Building

    7484 University Ave, La Mesa, CA 91942

    $3,600,000

    Office suites feature private restrooms and a circular layout centered on an atrium with floor-to-ceiling glass.

    View details
    Freeway-Visible Medical Building For Sale
    Freeway-Visible Medical Building For Sale

    7051 Alvarado Rd, La Mesa, CA 91942

    $6,950,000
    10,000 sqft

    Two-story, 10,000 SF medical building with freeway visibility.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Development Land Parcel
    Commercial Development Land Parcel

    42079 Roick, Temecula, CA 92590

    $1,249,000
    1.23 AC lot

    1.23-acre commercial-zoned land with plans for significant development in Temecula.

    View details
    Murrieta Land Near Medical Center
    Murrieta Land Near Medical Center

    28330 Joan Dunn Lane, Murrieta, CA 92563

    $1,690,700
    1,952 sqft 2.65 AC lot

    2.65-acre vacant land parcel near Loma Linda University Medical Center.

    View details
    High-Frontage General Commercial Land
    High-Frontage General Commercial Land

    70265 Hwy 111, Rancho Mirage, CA 92270

    $3,600,000

    Finished highway frontage along a major corridor offers flexible options under C-G zoning for a variety of commercial uses.

    View details
    General Commercial Highway Frontage Land
    General Commercial Highway Frontage Land

    70265 Hwy 111, Rancho Mirage, CA 92270

    $3,600,000
    4.72 AC lot

    Commercial land zoned C-G with frontage on Highway 111 in Rancho Mirage, CA.

    View details

    Off-Market Properties in San Diego, CA

    Consider similar Off-Market properties in San Diego, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    3703 4th Ave, Unit 11
    MEDICAL BUILDING

    3703 4th Ave, San Diego, CA 92103-4202

    Unit 11
    Value Estimation by Request
    1,704 sqft 0.10 AC lot
    View details
    4150 Regents Park Row
    MEDICAL BUILDING

    4150 Regents Park Row, San Diego, CA 92137

    $14,215,000
    Estimated value
    80,595 sqft 2.64 AC lot
    View details
    4120 La Jolla Vlg Dr, Unit 30
    MEDICAL BUILDING

    4120 La Jolla Vlg Dr, La Jolla, CA 92037-1406

    Unit 30
    $16,870,000
    Estimated value
    56,422 sqft 1.85 AC lot
    View details
    3630 Enterprise St
    MEDICAL BUILDING

    3630 Enterprise St, San Diego, CA 92110-3212

    Value Estimation by Request
    3,334 sqft 0.35 AC lot
    View details
    9999 Mira Mesa Blvd Ste, Unit 103
    MEDICAL BUILDING

    9999 Mira Mesa Blvd Ste, San Diego, CA 92131-1006

    Unit 103
    Value Estimation by Request
    8,181 sqft 0.66 AC lot
    View details
    3664 4th Ave
    MEDICAL BUILDING

    3664 4th Ave, San Diego, CA 92103-4106

    $3,105,000
    Estimated value
    0.15 AC lot
    View details
    3921 Goldfinch St
    MEDICAL BUILDING

    3921 Goldfinch St, San Diego, CA 92103-2926

    Value Estimation by Request
    1,521 sqft 0.12 AC lot
    View details
    3802 Clairemont Mesa Blvd
    MEDICAL BUILDING

    3802 Clairemont Mesa Blvd, San Diego, CA 92117-2712

    $1,830,000
    Estimated value
    6,768 sqft 0.51 AC lot
    View details
    6331 University Ave
    MEDICAL BUILDING

    6331 University Ave, San Diego, CA 92115-5814

    $2,885,000
    Estimated value
    18,346 sqft 0.66 AC lot
    View details

    San Diego, CA Medical Office Space Market Trends and Statistics

    Explore 72 medical office space for sale in San Diego, CA, showcased through 15 active listings on our real estate platform. These investment opportunities span a total of 72,666 square feet of properties for sale, with an estimated market value of $18,306,182.

    Sale prices for medical spaces in San Diego, CA start at $489,000, averaging $1,830,618, and reaching up to $4,099,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 402
    Office buildings 136
    Medical Office Space 47
    Coworking space 32
    Creative space 25

    Demographics Overview

    Population 1.38M
    Population Growth (5Y) -2.1%
    Median Household Income $109,172
    College Educated 31.4%

    High-Yield Neighborhoods for Investment

    Identify San Diego submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    San Diego $2.1M
    La Jolla $2.8M

    Taxes & Financing

    Tax Rate (average for all types) 1.17%
    Property Tax per SF $13.93 per SF
    Tax Rate vs County Average 0.03 pp below county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in San Diego County

    New Delisted

    Total CRE Inventory on Market (SF)

    Property Size Breakdown

    The majority of commercial real estate listings in San Diego fall within the 100,000+ square foot range.

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    Most Searched ZIP Codes in San Diego, CA

    • 92103
    • 92105
    • 92128
    • 92037
    • 92102
    • 92110
    • 92117
    • 92121
    • 92122
    • 92123
    • 92173

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