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    San Diego, CA Medical Office Space for Lease

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    22 properties
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    Medical Office Space Available
    Updated: Nov 24, 2025
    Medical Office Space Available

    5555 Reservoir Dr, San Diego, CA

    $28.56 SF/Yr
    600 sqft
    Next door to Alvarado Hospital and on‑site emergency services.
    Full service gross lease, including electricity, janitorial, and medical waste pickup.
    Green Line bus and trolley stop across the street.
    Free unreserved parking.
    Reserved parking lot for doctors.
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    Class A Office/Medical Building
    Updated: Apr 15
    Class A Office/Medical Building

    15373 Innovation Dr, San Diego, CA 92128

    Contact for pricing
    2,541 sqft
    Class A Office/Medical Building
    Available square footage 2,541 - 12,373 SF
    Convenient access to I‑15
    Building signage opportunity
    Covered parking available
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    Class A Medical Office Space
    Class A Medical Office Space

    8008 Frost Street, San Diego, CA 92123

    Contact for pricing
    9,266 sqft

    Medical office space available in a three-building campus.

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    Medical Office Space for Rent
    Medical Office Space for Rent

    9834 Genesee Ave, La Jolla, CA

    $53.40 SF/Yr
    1,961 sqft

    Medical office space near Scripps Memorial Hospital in La Jolla.

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    Medical Office Space Available
    Medical Office Space Available

    12395 El Camino Real, San Diego, CA

    $58.20 SF/Yr
    1,384 sqft

    Medical office space for lease with ample parking.

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    UTC Office Space For Rent
    UTC Office Space For Rent

    9333 Genesee Ave, San Diego, CA

    Contact for pricing
    7,541 sqft

    Office space in UTC, near hospitals and transportation.

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    Class A Office and Medical
    Class A Office and Medical

    4510- 4520 Executive Drive, San Diego, CA 92121

    Contact for pricing
    13,761 sqft

    Two-building Class A office and medical project for lease.

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    Kearny Mesa Office Space Available
    Kearny Mesa Office Space Available

    3760 Convoy St, San Diego, CA

    Contact for pricing
    1,265 sqft

    Dental build-out in a convenient location with excellent freeway access.

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    Medical Office Space Available
    Medical Office Space Available

    8901 Activity Rd, San Diego, CA 92126

    $28.20 SF/Yr
    2,764 sqft

    Medical office suites available in thriving San Diego medical corridor.

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    Medical Office Suite Available
    Medical Office Suite Available

    4076 Third Avenue |, San Diego, CA 92103

    Contact for pricing
    10,000 sqft

    4,466 SF medical office suite for rent.

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    Office Space in Mercy Medical Bldg
    Office Space in Mercy Medical Bldg

    4060 4th Ave, San Diego, CA

    Contact for pricing
    1,994 sqft

    Office space available for lease in San Diego, California.

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    Carmel Valley Medical Office Space
    Carmel Valley Medical Office Space

    4765 Carmel Mountain Rd, San Diego, CA

    Contact for pricing
    1,329 sqft

    Class-A medical office space in Carmel Valley for rent.

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    Class A Office/Medical Space
    Class A Office/Medical Space

    4510 Executive Dr, San Diego, CA

    Contact for pricing
    2,168 sqft

    Office and medical space with subterranean parking and amenities.

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    La Jolla Research Center Space
    La Jolla Research Center Space

    San Diego, CA

    Contact for pricing
    21,315 sqft

    Research center space for rent in La Jolla, CA.

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    Medical Office Space Available
    Medical Office Space Available

    6719 Alvarado Rd, San Diego, CA

    Contact for pricing
    1,306 sqft

    Medical office space for rent with tenant signage available.

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    La Jolla Medical Office Space
    La Jolla Medical Office Space

    5726 La Jolla Blvd, La Jolla, CA

    Contact for pricing
    1,500 sqft

    Turn-key medical office in La Jolla's Bird Rock community.

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    First Floor Office For Lease
    First Floor Office For Lease

    3863 - 3896 Clairemont Drive |, San Diego, CA 92117

    Contact for pricing

    Office space available for lease, suitable for medical or office use.

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    Kearny Mesa Medical Office Space
    Kearny Mesa Medical Office Space

    3750 Convoy St, San Diego, CA

    Contact for pricing
    2,452 sqft

    Medical office space in a convenient Kearny Mesa location.

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    UTC Medical/Office Space Available
    UTC Medical/Office Space Available

    9339 Genesee Ave, San Diego, CA

    Contact for pricing
    3,505 sqft

    Dental buildout, central UTC location, close to hospitals.

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    Rancho Bernardo Office/Medical Space
    Rancho Bernardo Office/Medical Space

    16440-16516 Bernardo Center Dr, San Diego, CA

    Contact for pricing
    1,516 sqft

    Office and medical spaces in Town Center Rancho Bernardo.

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    Medical Office Space Available
    Medical Office Space Available

    6699 Alvarado Rd, San Diego, CA

    Contact for pricing
    2,223 sqft

    Medical office space for rent near Alvarado Hospital.

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    Renovated Medical Building Suites Available
    Renovated Medical Building Suites Available

    3434 Midway Dr, San Diego, CA 92110

    $25.80 SF/Yr
    6,838 sqft

    Newly renovated medical building with suites available for lease.

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    Based on your search, we've compiled 37 Potential Opportunities for your consideration. Besides 22 Active listings in San Diego, CA, we suggest exploring alternatives. Similar 15 Properties for Sales.

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    San Ysidro Mixed-Use Investment Opportunity
    San Ysidro Mixed-Use Investment Opportunity

    165 W San Ysidro Blvd, San Ysidro, CA 92173

    $4,099,000
    7,989 sqft 0.32 AC lot

    New 7-unit mixed-use property near U.S.-Mexico border.

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    Mixed-Use Property in Opportunity Zone
    Mixed-Use Property in Opportunity Zone

    4170 Fairmount Ave, San Diego, CA 92105

    $999,000
    1,404 sqft

    Mixed-use property with high foot traffic in City Heights.

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    San Diego, CA Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in San Diego, CA with 22 listings featured on our commercial real estate exchange. The current inventory includes 13,547 square feet of properties with an estimated lease value of $194.16 SF/Yr.

    Estimated lease rates for Medical Office Space in San Diego, CA begin at $25.80 SF/Yr, with an average of $38.83 SF/Yr and extend to $58.20 SF/Yr.
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    Most Searched ZIP Codes in San Diego, CA

    • 92103
    • 92110
    • 92117
    • 92121
    • 92123
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