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    San Diego, CA Office Spaces for Lease

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    Found 558 office space listings for lease in San Diego, CA, averaging $21/SF/YR. Use lease type data to compare options faster.
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    Waterfront Office Space in Little Italy
    Waterfront Office Space in Little Italy

    1495 Pacific Hwy, San Diego, CA

    Modified gross Little Italy
    Contact for pricing
    7–12 people  1 space  1,895 sqft  0.23 acres

    Office space with unobstructed harbor views in Little Italy.

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    Office Space with 24/7 Access
    Office Space with 24/7 Access

    4901 Morena Blvd, San Diego, CA 92117

    Full service Bay Ho
    Contact for pricing
    3–5 people  841 sqft
    Highway access

    Office space featuring 24-hour access with a security gate and secured parking, with fiber internet connections available.

    On-Site Fitness Room  Basketball Court  Deli  Multiple Outside Picnic & Social Areas
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    Downtown San Diego Office/Retail Space
    Downtown San Diego Office/Retail Space

    737 Union St, San Diego, CA

    Modified gross Horton Plaza
    Contact for pricing
    4–7 people  3 spaces  1,121 sqft  1.37 acres

    Ground floor office/retail space in the heart of Downtown San Diego.

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    Office Space For Rent
    Office Space For Rent

    9640 Granite Ridge Drive, San Diego, CA 92123

    Serra Mesa
    Contact for pricing

    Office space available for rent in San Diego, CA.

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    Office Space For Rent
    Office Space For Rent

    9660 Granite Ridge Drive, San Diego, CA 92123

    Serra Mesa
    Contact for pricing

    Office space available for rent at Granite Ridge Drive.

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    Executive Office Suite
    Executive Office Suite

    3356-3368 2nd Ave, San Diego, CA 92103

    Park West
    Contact for pricing
    1 person  250 sqft

    Small private executive office with air conditioning and a private patio.

    Air conditioning  Private patio
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    Office Building with 24-Hour Gated Access
    Office Building with 24-Hour Gated Access

    4901 Morena Blvd, San Diego, CA 92117

    Full service Bay Ho
    Contact for pricing
    2–3 people  579 sqft
    Public transit  Highway access

    Office building with secured parking and 24-hour access through a security gate, plus on-site fitness and basketball amenities.

    On-Site Fitness Room  Basketball Court  Deli  Multiple Outside Picnic & Social Areas
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    Sublease Office Building
    Sublease Office Building

    5887 Copley Dr, San Diego, CA 92111

    Kearny Mesa
    Contact for pricing
    152–254 people  38,244 sqft

    Sublease office building offers suites ranging from 11,498 to 38,244 square feet.

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    Shell Office Space
    Shell Office Space

    600 B St, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    60–101 people  15,209 sqft

    Office space delivered in shell condition with NESW views.

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    Modern Office Campus For Rent
    Modern Office Campus For Rent

    13480 Evening Creek Dr N, San Diego, CA 92128

    Sabre Springs
    Contact for pricing
    63–105 people  15,850 sqft

    Re-imagined work campus with modern amenities and outdoor spaces.

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    Rancho Bernardo Office/Medical Space
    Rancho Bernardo Office/Medical Space

    16440-16516 Bernardo Center Dr, San Diego, CA

    Rancho Bernardo
    Contact for pricing
    6–10 people  2 spaces  1,516 sqft  4.59 acres

    Office and medical spaces in Town Center Rancho Bernardo.

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    Office Suite with Seven Offices
    Office Suite with Seven Offices

    8885 Rio San Diego Dr, San Diego, CA 92108

    Mission Valley East
    Contact for pricing
    10–17 people  1 space  2,595 sqft

    Office suite includes a reception area, seven private offices, a break room, and storage.

    Reception  Break room  Storage
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    Office Units With Secured Parking
    Office Units With Secured Parking

    4901 Morena Blvd, San Diego, CA 92117

    Full service Bay Ho
    Contact for pricing
    2–3 people  583 sqft
    Public transit  Highway access

    Office units with 24-hour access, a security gate, and excellent secured parking, plus on-site fitness and recreation amenities.

    Fitness room  Basketball court  Deli  Outside picnic areas
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    Mission Valley Leased Office Property
    Mission Valley Leased Office Property

    2555 Camino Del Rio South, San Diego, CA 92108

    Mission Valley East
    Contact for pricing
    0.91 acres

    Value-add, fully leased office building in central Mission Valley.

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    Corner Office Units
    Corner Office Units

    1431 Pacific Hwy, San Diego, CA 92101

    Modified gross Little Italy
    Contact for pricing
    8–14 people  1 space  2,114 sqft
    Public transit

    Office space with covered parking and potential signage or furniture availability.

    Covered parking  Building signage
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    Office Suite in Historic Campus
    Office Suite in Historic Campus

    1775 Hancock St, San Diego, CA 92110

    Midtown
    Contact for pricing
    22–38 people  5,704 sqft  Multi-tenant
    Highway access

    Office suites in a multi-building campus with underground parking, EV charging, and freeway visibility off I-5.

    Underground parking  EV car charging stations  On-site trolley access  Sky lights
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    Bright Office Space with Views
    Bright Office Space with Views

    303 A St, San Diego, CA

    Full service Core-Columbia
    Contact for pricing
    5–8 people  1 space  1,272 sqft  0.23 acres

    Corner office space featuring floor-to-ceiling glass and downtown views.

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    Urban Office Space with Patio
    Urban Office Space with Patio

    3043 4th Ave, San Diego, CA

    Park West
    Contact for pricing
    69–115 people  17,300 sqft  0.35 acres

    Office space featuring indoor/outdoor connectivity and covered parking.

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    Office Campus with Underground Parking
    Office Campus with Underground Parking

    2150 W Washington St, San Diego, CA 92110

    Midtown
    Contact for pricing
    7–12 people  1,863 sqft

    Four-building office campus offers scalable suite sizes plus underground parking and on-site EV charging.

    Underground parking  EV car charging stations  On-site ownership and property management
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    Office Space Available for Lease
    Office Space Available for Lease

    8690 Balboa Ave., San Diego, CA 92123

    Kearny Mesa
    Contact for pricing
    Built 2026

    Office property available for lease in San Diego, CA.

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    Office Space Available for Lease
    Office Space Available for Lease

    1775 Hancock St., San Diego, CA 92110

    Midtown
    Contact for pricing
    1 space  Built 2026

    Office property available for lease in San Diego, CA.

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    Office Building with Conferencing Facility
    Office Building with Conferencing Facility

    7676 Hazard Center Dr, San Diego, CA 92108

    Full service Mission Valley East
    Contact for pricing
    38–64 people  1 space  9,685 sqft
    Public transit

    Office building with 24-hour access, signage, and an on-site property manager, plus conferencing and building amenities.

    24 Hour Access  Conferencing Facility  Convenience Store  Dry Cleaner
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    Historic Office Campus with Trolley Access
    Historic Office Campus with Trolley Access

    1775 Hancock St, San Diego, CA 92110

    Midtown
    Contact for pricing
    5–8 people  1,310 sqft

    Historic four-building office campus offers underground parking, EV charging, and suite sizes from 900 to 10,000 SF.

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    Historic Office Campus with Trolley Access
    Historic Office Campus with Trolley Access

    1775 Hancock St, San Diego, CA 92110

    Midtown
    Contact for pricing
    9–15 people  2 spaces  2,321 sqft
    Highway access

    Four-building office campus with underground parking, EV charging, and on-site trolley access near I-5.

    EV Car Charging Stations  On-site trolley access  Freeway visible signage  Monument signage
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    Most Searched ZIP Codes in San Diego, CA

    • 92121
    • 92101
    • 92123
    • 92130
    • 92108
    • 92128
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    • 92127
    • 92131
    • 92110
    • 92111
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