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    San Diego, CA Office Spaces for Lease

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    Found 558 office space listings for lease in San Diego, CA, averaging $21/SF/YR. Use lease type data to compare options faster.
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    Office Space Available For Rent
    Office Space Available For Rent

    9560 Candida St, San Diego, CA

    Mira Mesa
    Contact for pricing
    1 person  7 spaces  120 sqft  0.63 acres

    Office space available for rent with 120 square feet.

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    San Diego Office Space Available
    San Diego Office Space Available

    4025 Camino Del Rio S, San Diego, CA

    Grantville
    Contact for pricing
    6–11 people  1,681 sqft  1.34 acres

    Office space available for rent in San Diego, CA.

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    Office Space Available For Rent
    Office Space Available For Rent

    16409 West Bernardo Drive, San Diego, CA 92127

    Rancho Bernardo
    Contact for pricing
    211–352 people  52,800 sqft

    52,800 sqft office space available for lease.

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    San Diego Office Space Available
    San Diego Office Space Available

    12235 El Camino Real, San Diego, CA 92130

    Torrey Preserve
    Contact for pricing
    223–372 people  55,900 sqft  Built 2026

    Office space available for rent in San Diego, CA.

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    Office Suites with Courtyard Access
    Office Suites with Courtyard Access

    12625 High Bluff Dr, San Diego, CA 92130

    Full service Carmel Valley
    Contact for pricing
    7–12 people  1 space  1,912 sqft  Spanish Colonial

    Office suites in a Spanish Colonial-style building include card-key security, separate metering, and access to a landscaped courtyard.

    High-tech security system  Open-air courtyard with garden and water feature  Walking trail with direct access to One Paseo  Spa-quality shower and locker rooms
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    Convenient Office Space Near I-15
    Convenient Office Space Near I-15

    3655 Ruffin Rd., San Diego, CA 92123

    Serra Mesa
    Contact for pricing

    Office space with easy access to I-15 and amenities.

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    Office Suite with Reception and Conference
    Office Suite with Reception and Conference

    404 Camino del Rio S, San Diego, CA 92108

    Mission Valley West
    Contact for pricing
    37–62 people  1 space  9,412 sqft
    9 private offices  1 meeting room  Highway access

    Office suite with prominent reception, large conference room, private offices, and flexible open work areas.

    On-site coffee cart
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    Class A Medical Office Suites
    Class A Medical Office Suites

    8010 Frost St, San Diego, CA 92123

    Birdland
    Contact for pricing
    Multi-tenant  1,418 sqft
    Highway access

    Class A suites within a three-building medical campus, offering structured and surface parking with on-site management.

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    Class A Office Building
    Class A Office Building

    13520 Evening Creek Dr N, San Diego, CA 92128

    Class A Sabre Springs
    Contact for pricing
    7–11 people  1,771 sqft

    For lease Class A offices with on-site management, security, and EV charging, plus outdoor meeting areas with WiFi.

    Adjacent to regional transportation hub  Fitness center with shower and locker facilities  Access to 56 bike path and MTS Station  On-site management and security
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    Office Suites with Enhanced Amenities
    Office Suites with Enhanced Amenities

    550 W C St, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    27–45 people  6,781 sqft
    Public transit

    Office suites with enhanced lobby, gym, conference room, and EV-ready parking, just steps from transit and downtown destinations.

    2.0/1,000 SF parking  Enhanced lobby  Dining  Outdoor amenities
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    Office Building with Conference Room
    Office Building with Conference Room

    550 W C St, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    19–32 people  4,828 sqft

    Office building with an on-site, fully equipped conference room and enhanced lobby, dining, and outdoor amenities.

    Enhanced lobby  Dining  Outdoor amenities  EV charging stations
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    Office Space in San Diego
    Office Space in San Diego

    7084 Miramar Rd, San Diego, CA

    Miramar
    Contact for pricing
    32–54 people  1 space  8,237 sqft  0.66 acres

    8,237 SF office space available for rent.

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    Mission Valley Creative Office Space
    Mission Valley Creative Office Space

    404 Camino del Rio S, San Diego, CA

    Mission Valley West
    Contact for pricing
    23–39 people  6 spaces  5,937 sqft  5.03 acres

    Corner suite with views, potential expansion, and high-end finishes.

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    Renovated Office Space in Old Town
    Renovated Office Space in Old Town

    2251 San Diego Ave, San Diego, CA

    Old Town
    Contact for pricing
    5–8 people  11 spaces  1,293 sqft  5.1 acres

    Modern Spanish-style office with convenient access to transportation and amenities.

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    Office Suite with Floor-to-Ceiling Windows
    Office Suite with Floor-to-Ceiling Windows

    404 Camino del Rio S, San Diego, CA 92108

    Class A Mission Valley West
    Contact for pricing
    10–17 people  1 space  2,569 sqft
    Highway access

    Office space in Mission Valley with floor-to-ceiling windows, flexible suite sizes, and on-site coffee cart service.

    On-site coffee cart
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    Class A Medical Office Space
    Class A Medical Office Space

    8010 Frost St, San Diego, CA 92123

    Birdland
    Contact for pricing
    3,136 sqft
    Highway access

    Class A medical office space within a three-building campus adjacent to major hospitals and with surface and reserve parking.

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    Class A Medical Office Suite
    Class A Medical Office Suite

    8010 Frost St, San Diego, CA 92123

    Birdland
    Contact for pricing
    Multi-tenant  2,997 sqft
    Highway access

    Class A medical office space is available within a three-building campus with professional on-site management and parking.

    On-site professional property management
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    Ground Floor Office Suite with Exterior Entrance
    Ground Floor Office Suite with Exterior Entrance

    6363 Greenwich Dr, San Diego, CA 92122

    Class A University City
    Contact for pricing
    18–31 people  4,713 sqft  Ground Floor
    Highway access

    Ground floor office suite with a dedicated exterior entrance and immediate access to Interstate 805.

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    Retail and Office Space Available
    Retail and Office Space Available

    10066-10068 Pacific Heights Boulevard, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing

    Retail and office spaces for rent in a vibrant shopping center.

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    La Jolla Office Space Available
    La Jolla Office Space Available

    San Diego, CA

    Little Italy
    Contact for pricing
    11–18 people  3 spaces  2,843 sqft  0.32 acres

    2,843 SF office space for lease in La Jolla.

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    Miramar Road Mixed-Use Center
    Miramar Road Mixed-Use Center

    7030-7090 Miramar Road, San Diego, CA 92121

    Miramar
    Contact for pricing

    Mixed-use center with high street exposure on Miramar Road.

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    Point Loma Office/Retail Space
    Point Loma Office/Retail Space

    2810 Canon St, San Diego, CA

    Triple net (NNN) La Playa
    Contact for pricing
    4–8 people  2 spaces  1,200 sqft  0.41 acres

    Renovated office/retail space in the heart of Point Loma.

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    Warehouse and Office Flex Space
    Warehouse and Office Flex Space

    10110 Sorrento Valley Road, San Diego, CA 92121

    Triple net (NNN) Sorrento Valley
    Contact for pricing
    18,552 sqft

    Flex building offering a warehouse component alongside dedicated office space totaling 18,552 SF.

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    Flex Space Suite with Grade Level Door
    Flex Space Suite with Grade Level Door

    8515 Arjons Dr, San Diego, CA 92126

    Triple net (NNN) Miramar
    Contact for pricing
    2,506 sqft  1 drive-in

    Move-in-ready flex suite with reception, private offices, restrooms, and warehouse space served by a grade level loading door.

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    • 92121
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