Office

La Mesa, CA Office Spaces for Lease

Notify Me
List
Map
San Diego, CA Lemon Grove, CA Spring Valley, CA El Cajon, CA Santee, CA National City, CA Lakeside, CA Bonita, CA
17 properties
Sort:
Renovated Office Space in La Mesa
Updated: Mar 10
Renovated Office Space in La Mesa

9633 Grossmont Summit Dr., La Mesa, CA 91941

$1,000/Mo
2,000 sqft
Excellent freeway access and visibility from I‑8.
Move‑in ready, beautifully renovated office space.
Flexible workspace: approximately 1,300 - 2,000 divisible square feet.
Located in a central, professional area near Mt. Helix in La Mesa.
Includes air conditioning and a private bathroom.
View details
Boutique Medical Office Space
Updated: Nov 25, 2025
Boutique Medical Office Space

5200 Lake Murray Blvd, La Mesa, CA

$6.02 SF/Yr
900 sqft
Prime location at a signalized intersection with I‑8 Freeway on‑ramp access.
Close proximity to major hospitals: Sharp Grossmont and UC San Diego Health East Campus Medical Center.
Turnkey medical office space with pristine finishes and high‑end aesthetics.
Newly renovated with fresh paint, new LED lighting, and new tile flooring.
Boutique medical office setting.
View details
La Mesa Office/Retail Building
La Mesa Office/Retail Building

8415 La Mesa Blvd, La Mesa, CA

$23.04 SF/Yr
5,942 sqft

Office/retail building available for sale in La Mesa, CA.

View details
Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
Plug-and-Play Office Suite
Plug-and-Play Office Suite

9019 Park Plaza Dr, La Mesa, CA 91942

Contact for pricing
462 sqft

Modern office suite with a private office, open workspace, and an in-suite restroom for immediate occupancy.

View details
La Mesa Office Space Available
La Mesa Office Space Available

8911 La Mesa Blvd, La Mesa, CA

Contact for pricing
1,100 sqft

Office space available for rent in La Mesa, California.

View details
La Mesa Office Space Available
La Mesa Office Space Available

7373 University Ave, La Mesa, CA

Contact for pricing
2,058 sqft

Office space for rent in La Mesa, California.

View details
Furnished Private Office Suite
Furnished Private Office Suite

4752 Palm Avenue, La Mesa, CA 91942

Contact for pricing

Move-in-ready furnished office with a private entrance, suited for small professional teams needing space for up to three desks.

View details
La Mesa Office Property
La Mesa Office Property

5400 Connecticut Ave, La Mesa, CA

$5.46 SF/Yr

Fully leased office property in La Mesa, California.

View details
La Mesa Office Space Available
La Mesa Office Space Available

5565 Grossmont Center Dr, La Mesa, CA

Contact for pricing
2,524 sqft

Office space for rent near Sharp Grossmont Hospital.

View details
La Mesa Multi-Tenant Office
La Mesa Multi-Tenant Office

7484 University Ave, La Mesa, CA

Contact for pricing
873 sqft

Multi-tenant office building in La Mesa with ample parking.

View details
La Mesa Retail/Office Space
La Mesa Retail/Office Space

5555 Jackson Dr, La Mesa, CA 91942

$27 SF/Yr

Retail and office spaces available for lease in La Mesa.

View details
Medical Suite for Lease
Medical Suite for Lease

8860 Center Dr, La Mesa, CA

Contact for pricing
3,343 sqft

Medical suite available for lease in La Mesa, California.

View details
La Mesa Retail/Office Building
La Mesa Retail/Office Building

4730 3rd St, La Mesa, CA 91941

Contact for pricing
6,862 sqft

Two-story retail/office building in the heart of La Mesa.

View details
La Mesa Office Space Available
La Mesa Office Space Available

5575 Lake Park Way, La Mesa, CA 91942

$26.40 SF/Yr

Office units for rent in La Mesa, California.

View details
Office Space for Lease
Office Space for Lease

5360 Jackson Dr, La Mesa, CA 91942

Contact for pricing

Office space available for lease in La Mesa, California.

View details
Office Space Available For Lease
Office Space Available For Lease

7853 El Cajon Blvd, La Mesa, CA 91941

$19.80 SF/Yr

Office property available for lease.

View details
Office Space Available For Lease
Office Space Available For Lease

5480 Baltimore Dr, La Mesa, CA 91942

Contact for pricing

Office space for lease at 5480 Baltimore Dr, La Mesa.

View details
Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 17 Active listings in La Mesa, CA, we suggest exploring alternatives. Similar 3 Properties for Sales.

Similar Spaces for Sale in La Mesa, CA

Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

Landmark Office Building in La Mesa
Landmark Office Building in La Mesa

7578 El Cajon Blvd, La Mesa, CA 91942

Contact for pricing
22,500 sqft 0.84 AC lot

Three-story office building on a highly visible corner lot.

View details
Renovated Second-Level Office Suite
Renovated Second-Level Office Suite

9633 Grossmont Summit Dr., La Mesa, CA 91941

Contact for pricing
2,000 sqft

Move-in-ready office suite with air conditioning, private bathroom, and parking included, with strong I-8 visibility.

View details
Freeway-Visible Medical Building For Sale
Freeway-Visible Medical Building For Sale

7051 Alvarado Rd, La Mesa, CA 91942

$6,950,000
10,000 sqft

Two-story, 10,000 SF medical building with freeway visibility.

View details

La Mesa, CA Office Spaces Market Trends and Statistics

Explore Office Spaces leasing options in La Mesa, CA with 17 listings featured on our commercial real estate exchange. The current inventory includes 11,773 square feet of properties with an estimated lease value of $38.31 SF/Yr.

Estimated lease rates for Office Spaces in La Mesa, CA begin at $1.15 SF/Yr, with an average of $7.66 SF/Yr and extend to $23.04 SF/Yr.
List
Map