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La Mesa, CA Office Properties & Spaces for Lease

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18 results
Boutique Medical Office Space
$6 SF/Yr
900 SF

Boutique Medical Office Space

5200 Lake Murray Blvd, La Mesa, CA

Medical office space with pristine finishes and high-end aesthetics.

  • Prime location at a signalized intersection with I‑8 Freeway on‑ramp access.
  • Close proximity to major hospitals: Sharp Grossmont and UC San Diego Health East Campus Medical Center.
  • Turnkey medical office space with pristine finishes and high‑end aesthetics.
  • Newly renovated with fresh paint, new LED lighting, and new tile flooring.
  • Boutique medical office setting.
Updated: Nov 25, 2025
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Turn-Key Office Suites Available
$2 SF/Yr

Turn-Key Office Suites Available

3855 Avocado Blvd, La Mesa, CA

Turn-key office suites with shared reception and waiting area.

  • Turn‑key office suites ready for immediate occupancy.
  • Short term leases available, offering flexibility.
  • Shared reception and waiting area.
  • Executive suites available.
  • $500/month rental price.
Updated: Nov 24, 2025
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La Mesa Office/Retail Building
$23 SF/Yr
5,942 SF

La Mesa Office/Retail Building

Office/retail building available for sale in La Mesa, CA.

8415 La Mesa Blvd, La Mesa, CA
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Private Office in Historic Building
$54 SF/Yr

Private Office in Historic Building

Private office space available for rent in historic building.

8200 Allison Avenue, La Mesa, CA 91942
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La Mesa Office Space Available
$1.75 SF/Yr
1,100 SF

La Mesa Office Space Available

Office space available for rent in La Mesa, California.

8911 La Mesa Blvd, La Mesa, CA
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La Mesa Office Property
Contact for pricing

La Mesa Office Property

Fully leased office property in La Mesa, California.

5400 Connecticut Ave, La Mesa, CA
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La Mesa Multi-Tenant Office
$1.15 SF/Yr
873 SF

La Mesa Multi-Tenant Office

Multi-tenant office building in La Mesa with ample parking.

7484 University Ave, La Mesa, CA
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La Mesa Office Space Available
$2 SF/Yr
2,058 SF

La Mesa Office Space Available

Office space for rent in La Mesa, California.

7373 University Ave, La Mesa, CA
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La Mesa Office Space Available
Contact for pricing
2,524 SF

La Mesa Office Space Available

Office space for rent near Sharp Grossmont Hospital.

5565 Grossmont Center Dr, La Mesa, CA
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La Mesa Office Space Available
$2 SF/Yr
831 SF

La Mesa Office Space Available

831 square feet office space for rent in La Mesa.

7777 Alvarado Rd, La Mesa, CA
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Office Space Available For Lease
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Office Space Available For Lease

Office space for lease at 7171 Alvarado Rd, La Mesa.

7171 Alvarado Rd, La Mesa, CA 91942
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La Mesa Retail/Office Space
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La Mesa Retail/Office Space

Retail and office spaces available for lease in La Mesa.

5555 Jackson Dr, La Mesa, CA 91942
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Medical Suite for Lease
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3,343 SF

Medical Suite for Lease

Medical suite available for lease in La Mesa, California.

8860 Center Dr, La Mesa, CA
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La Mesa Retail/Office Building
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6,862 SF

La Mesa Retail/Office Building

Two-story retail/office building in the heart of La Mesa.

4730 3rd St, La Mesa, CA 91941
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Office Space for Lease
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Office Space for Lease

Office space available for lease in La Mesa, California.

5360 Jackson Dr, La Mesa, CA 91942
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La Mesa Office Space Available
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La Mesa Office Space Available

Office units for rent in La Mesa, California.

5575 Lake Park Way, La Mesa, CA 91942
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Office Space Available For Lease
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Office Space Available For Lease

Office property available for lease.

7853 El Cajon Blvd, La Mesa, CA 91941
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Office Space Available For Lease
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Office Space Available For Lease

Office space for lease at 5480 Baltimore Dr, La Mesa.

5480 Baltimore Dr, La Mesa, CA 91942
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Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 18 Active listings in La Mesa, CA, we suggest exploring alternatives. Similar 3 Properties for Sales.

Explore Similar Spaces for Sale in La Mesa, CA

Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

Renovated Office Space in La Mesa
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Renovated Office Space in La Mesa

Move-in ready office space with freeway access and parking.

9633 Grossmont Summit Dr., La Mesa, CA 91941
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La Mesa Village Twin-Home
$1,650,000
2,600 SF

La Mesa Village Twin-Home

Craftsman twin-home zoned for residential and commercial use.

8318 Allison, La Mesa, CA 91942
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Freeway-Visible Medical Building For Sale
$6,950,000
10,000 SF

Freeway-Visible Medical Building For Sale

Two-story, 10,000 SF medical building with freeway visibility.

7051 Alvarado Rd, La Mesa, CA 91942
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La Mesa, CA Office properties & Spaces Leasing Opportunities Market Analysis

Explore Office properties & Spaces leasing options in La Mesa, CA with 18 listings featured on our commercial real estate exchange. The current inventory includes 537,835,320 square feet of properties with an estimated lease value of $0.00 SF/Yr.

Estimated lease rates for Office properties & Spaces in La Mesa, CA begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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