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    Rancho Santa Margarita, CA
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    Rancho Santa Margarita, CA Office Properties & Spaces for Lease

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    Los Angeles, CA San Diego, CA San Francisco, CA
    11 results
    Office Building with Mountain Views
    $2 SF/Yr
    18,538 SF

    Office Building with Mountain Views

    22362 Gilberto, Rancho Santa Margarita, CA 92688

    Two-story office building in South Orange County available for rent.

    • Prime South Orange County location
    • Spectacular panoramic Saddleback Mountain views
    • Easy access to the 241 Foothill Transportation Corridor
    • Elevator served office building
    • Corporate headquarters building with formal entry lobby
    Updated: Nov 26, 2025
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    Rancho Santa Margarita Retail Center
    Contact for pricing
    8,500 SF

    Rancho Santa Margarita Retail Center

    29821-29941 Aventura, Rancho Santa Margarita, CA 92688

    Multi-tenant center near 241 Toll Road in Rancho Santa Margarita.

    • Strongest income demographics in Orange County
    • Strategically located off the 241 Toll Road
    • United States Postal Service is the driver of the center
    • Excellent daytime population from adjacent business parks
    • Excellent center to gain a foothold in this high demand trade area
    Updated: Mar 25
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    Medical Office Condo For Rent
    $2 SF/Yr
    2,360 SF

    Medical Office Condo For Rent

    Medical office condo featuring private offices, conference room, and balcony.

    30212 Tomas, Rancho Santa Margarita, CA
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    Medical Office Space For Rent
    Contact for pricing
    18,400 SF

    Medical Office Space For Rent

    Medical office space in Rancho Santa Margarita available for lease.

    29472 Avenida de las Banderas, Rancho Santa Margarita, CA 92688
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    Office Space Available For Lease
    Contact for pricing

    Office Space Available For Lease

    Office property available for lease in Rancho Santa Margarita, CA.

    30212 Tomas, Rancho Santa Margarita, CA 92688
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    Medical Office Sublease Opportunity
    Contact for pricing
    2,835 SF

    Medical Office Sublease Opportunity

    Medical office space available for sublease in Rancho Santa Margarita.

    22032 El Paseo, Rancho Santa Margarita, CA 92688
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    Rancho Santa Margarita Office Space
    $22 SF/Yr

    Rancho Santa Margarita Office Space

    Furnished office spaces with mountain views and convenient access.

    30211 Avenida de las Banderas Suite 200, Rancho Santa Margarita, CA 92688
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    Rancho Santa Margarita Office Building
    Contact for pricing
    8,309 SF

    Rancho Santa Margarita Office Building

    Office building available, early education/school permitted.

    28672 Deerpath, Rancho Santa Margarita, CA
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    Modern Flex Space Available
    Contact for pricing

    Modern Flex Space Available

    Flex project in prime location with modern units.

    22521 Avenida Empresa, Rancho Santa Margarita, CA 92688
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    Rancho Santa Margarita Retail Space
    Contact for pricing
    2,317 SF

    Rancho Santa Margarita Retail Space

    Retail spaces available in Rancho Santa Margarita, ranging from 1,610-2,317

    29821-29941 Aventura, Rancho Santa Margarita, CA 92688
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    Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 11 Active listings in Rancho Santa Margarita, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Office properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Class A Office Space Available
    $2 SF/Yr
    3,013 SF

    Class A Office Space Available

    High-image office space with excellent amenities and convenient parking.

    27442 Portola Parkway, Lake Forest, CA 92610
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    Class A Office Space Available
    $2 SF/Yr
    58,560 SF

    Class A Office Space Available

    High-image office campus with excellent amenities and access.

    27422 Portola Parkway, Lake Forest, CA 92610
    View details
    Prime Office Space in Mission Viejo
    Contact for pricing

    Prime Office Space in Mission Viejo

    Exceptional leasing opportunity in a vibrant Mission Viejo location.

    Mission Viejo, CA 92692
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    Mission Viejo Retail Spaces Available
    Contact for pricing
    3,406 SF

    Mission Viejo Retail Spaces Available

    Retail and office spaces available in Mission Viejo, California.

    27001 La Paz Rd, Mission Viejo, CA 92691
    View details

    Similar Spaces for Sale in Rancho Santa Margarita, CA

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    Rancho Santa Margarita Retail Unit
    Contact for pricing
    1,600 SF

    Rancho Santa Margarita Retail Unit

    1,600 SF retail unit with rear roll-up door.

    29851 Aventura, Rancho Santa Margarita, CA 92688
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    Upgraded Office in Prime Location
    $6,950,000
    21,810 SF

    Upgraded Office in Prime Location

    Highly upgraded office building with potential warehouse conversion.

    30242 Esperanza, Rancho Santa Margarita, CA 92688
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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Fontana Commercial Land Lease
    $0.01 SF/Yr
    1,565 SF

    Prime Fontana Commercial Land Lease

    4.33-acre commercial land for ground lease in Fontana, CA.

    16203 Foothill Boulevard, Fontana, CA 92335
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    Prime Commercial Land for Lease
    Contact for pricing
    75,000 SF

    Prime Commercial Land for Lease

    Highly visible 3.59-acre commercial land in San Luis Obispo.

    2040 Prado Road, San Luis Obispo, CA 93401
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    High Visibility Land For Lease
    Contact for pricing

    High Visibility Land For Lease

    1.41 acres at signalized intersection available for ground lease.

    1400 Willow Pass Rd, Concord, CA 94520
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    Chico Commercial Land For Lease
    $5,000/Mo
    9,000 SF

    Chico Commercial Land For Lease

    Prime corner lot in Chico for build to suit.

    996 E 1st Avenue, Chico, CA 95926
    View details

    Rancho Santa Margarita, CA Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Rancho Santa Margarita, CA with 11 listings featured on our commercial real estate exchange. The current inventory includes 20,898 square feet of properties with an estimated lease value of $4 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Rancho Santa Margarita, CA begin at $2 SF/Yr, with an average of $2 SF/Yr and extend to $2 SF/Yr.
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    Most Searched ZIP Codes in Rancho Santa Margarita, CA

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